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7541“…The present functional magnetic resonance imaging study investigated the specialization and integration of dorsal and ventral streams using tasks of object recognition and location detection. …”
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7542“…The HIV-1 integrase enzyme is responsible for one of the key stages of retroviral replication; it acts as a catalyst for the integration of viral cDNA into the cell’s genome. Inhibitors of HIV-1 integration have been under development for over 10 years; yet, only one integration inhibitor, raltegravir, has been approved for clinical use so far. …”
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7543por Gulyás-Kovács, Attila“…This study introduces an integrative framework that improves the accuracy of such predictions, relative to previous approaches, by combining multiple coevolution detectors and incorporating structural contact information. …”
Publicado 2012
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7544por Freund, Patrick, Wheeler-Kingshott, Claudia A, Nagy, Zoltan, Gorgoraptis, Nikos, Weiskopf, Nikolaus, Friston, Karl, Thompson, Alan J, Hutton, Chloe“…The authors used diffusion tensor imaging to assess white matter integrity in the CST, T1-weighted imaging to measure cross-sectional spinal cord area and functional MRI to compare motor task-related brain activations. …”
Publicado 2012
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7545“…RESULTS: Here, we derive a robust statistical approach for QTL mapping that accommodates a certain degree of misspecification of the true model by incorporating integrated square errors into the genetic mapping framework. …”
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7547por Scicluna, Helen A, Grimm, Michael C, O’Sullivan, Anthony J, Harris, Peter, Pilotto, Louis S, Jones, Philip D, McNeil, H Patrick“…BACKGROUND: The University of New South Wales (UNSW) Faculty of Medicine replaced its old content-based curriculum with an innovative new 6-year undergraduate entry outcomes-based integrated program in 2004. This paper is an initial evaluation of the perceived and assessed clinical capabilities of recent graduates of the new outcomes-based integrated medical program compared to benchmarks from traditional content-based or process-based programs. …”
Publicado 2012
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7548“…Another possible strategy is to integrate information of individual cells by cell-to-cell interaction such as quorum sensing. …”
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7549“…The cell wall integrity (CWI) signal transduction pathway, which has been well-studied in the yeast Saccharomyces cerevisiae, plays an important role in the regulation of cell wall biogenesis. …”
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7550“…We suggest that this shows that the word-trained dogs interpret pointing as a spatial directive, which they integrate into the fetching game, presumably assuming that pointing is relevant to finding the requested object.…”
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7551por Phillips, Brian S., Measor, Philip, Zhao, Yue, Schmidt, Holger, Hawkins, Aaron R.“…Optofluidic platforms used for biomolecular detection require spectral filtering for distinguishing analyte signals from unwanted background. Towards a fully integrated platform, an on-chip filter is required. …”
Publicado 2010
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7553“…While fusion is computationally attractive, it poses a significant challenge, requiring the integration of quantitatively different signals. We used functional magnetic resonance imaging (fMRI) to provide evidence that dorsal visual area V3B/KO meets this challenge. …”
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7554“…Although agonist binding and channel gating have long been considered to be separate processes in the activation of ligand-gated ion channels, this correlation implies that the catch-and-hold conformational changes are energetically linked and together comprise an integrated process having a common structural basis. …”
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7555“…While this so-called graded release property has been known for some time, its functional importance to the integrated behavior of the cardiac ventricular myocyte has not been fully appreciated. …”
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7556“…Word pairs may be integrative (i.e., combination of two concepts into one meaningful entity; e.g., fruit—cake), thematically related (i.e., connected in time and place; e.g., party—cake), and/or taxonomically related (i.e., shared features and category co-members; e.g., muffin—cake). …”
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7558
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7559“…These three synaptic systems use distinct mechanisms in order to generate Ca(2+) signals that are specialized for specific modes of neurotransmitter release and post-synaptic signal integration. In this review, we first describe the repertoire of Ca(2+) regulatory mechanisms that generate and regulate the amplitude and timing of Ca(2+) fluxes during synaptic transmission and then explore how these mechanisms interact to generate the unique functional properties of each of the Purkinje neuron synapses.…”
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7560por Webb-Robertson, Bobbie-Jo, Kreuzer, Helen, Hart, Garret, Ehleringer, James, West, Jason, Gill, Gary, Duckworth, Douglas“…In addition, we show graphically the strengths and weaknesses of each dataset in respect to class prediction and how the integration of these datasets strengthens the overall model.…”
Publicado 2012
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