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1701por Taylor, Emma L., Thompson, Paul A., Manktelow, Nicholas, Flynn, Samantha, Gillespie, David, Bradshaw, Jill, Gore, Nick, Liew, Ashley, Lovell, Mark, Sutton, Kate, Richards, Caroline, Petrou, Stavros, Langdon, Peter E., Grant, Gemma, Cooper, Vivien, Seers, Kate, Hastings, Richard P.“…BACKGROUND: One in five children with an intellectual disability in the UK display behaviours that challenge. …”
Publicado 2023
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1702“…Since the first of its core patents expired in March, 2005, we are in a position to view the entire lifespan of the patent, examining how the intellectual property rights have impacted its use in the biomedical community. …”
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1703por Kajantie, E, Räikkönen, K, Henriksson, M, Forsén, T, Heinonen, K, Pesonen, A K, Leskinen, J T, Laaksonen, I, Paile-Hyvärinen, M, Osmond, C, Barker, D J P, Eriksson, J G“…BACKGROUND: People who score poorly in intellectual ability tests have shorter life expectancy. …”
Publicado 2009
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1704por Pagan, Cecile, Botros, Hany Goubran, Poirier, Karine, Dumaine, Anne, Jamain, Stéphane, Moreno, Sarah, de Brouwer, Arjan, Van Esch, Hilde, Delorme, Richard, Launay, Jean-Marie, Tzschach, Andreas, Kalscheuer, Vera, Lacombe, Didier, Briault, Sylvain, Laumonnier, Frédéric, Raynaud, Martine, van Bon, Bregje W, Willemsen, Marjolein H, Leboyer, Marion, Chelly, Jamel, Bourgeron, Thomas“…BACKGROUND: Intellectual disability (ID) is frequently associated with sleep disorders. …”
Publicado 2011
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1705por Mazumdar, Maitreyi, Bellinger, David C, Gregas, Matthew, Abanilla, Kathleen, Bacic, Janine, Needleman, Herbert L“…OBJECTIVES: We sought to assess the relationship between early life environmental lead exposure and intellectual function in adulthood. We also attempted to identify which time period blood-lead concentrations are most predictive of adult outcome. …”
Publicado 2011
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1706
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1707“…OBJECTIVE: To investigate parents' experiences of follow-up by general practitioners (GPs) of children with intellectual disabilities (ID) and comorbid behavioural and/or psychological problems. …”
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1708por Bassani, Silvia, Cingolani, Lorenzo A., Valnegri, Pamela, Folci, Alessandra, Zapata, Jonathan, Gianfelice, Antonella, Sala, Carlo, Goda, Yukiko, Passafaro, Maria“…Mutations in TSPAN7—a member of the tetraspanin protein superfamily—are implicated in some forms of X-linked intellectual disability. Here we show that TSPAN7 overexpression promotes the formation of filopodia and dendritic spines in cultured hippocampal neurons from embryonic rats, whereas TSPAN7 silencing reduces head size and stability of spines and AMPA receptor currents. …”
Publicado 2012
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1709por Gong, Xiaohong, Jiang, Yu-wu, Zhang, Xin, An, Yu, Zhang, Jun, Wu, Ye, Wang, Jingmin, Sun, Yangfei, Liu, Yanyan, Gao, Xuewu, Shen, Yiping, Wu, Xiru, Qiu, Zilong, Jin, Li, Wu, Bai-Lin, Wang, Hongyan“…Intellectual disability (ID) is a heterogeneous disorder caused by chromosomal abnormalities, monogenic factors and environmental factors. 22q13 deletion syndrome is a genetic disorder characterized by severe ID. …”
Publicado 2012
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1711por Halgren, C, Kjaergaard, S, Bak, M, Hansen, C, El-Schich, Z, Anderson, CM, Henriksen, KF, Hjalgrim, H, Kirchhoff, M, Bijlsma, EK, Nielsen, M, den Hollander, NS, Ruivenkamp, CAL, Isidor, B, Le Caignec, C, Zannolli, R, Mucciolo, M, Renieri, A, Mari, F, Anderlid, B-M, Andrieux, J, Dieux, A, Tommerup, N, Bache, I“…Corpus callosum abnormalities are common brain malformations with a wide clinical spectrum ranging from severe intellectual disability to normal cognitive function. …”
Publicado 2012
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1712por Lennox, Nicholas, Ware, Robert, Carrington, Suzanne, O’Callaghan, Michael, Williams, Gail, McPherson, Lyn, Bain, Chris“…BACKGROUND: Adolescents with intellectual disability often have poor health and healthcare. …”
Publicado 2012
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1713por Siew, Wei-Hong, Tan, Kai-Leng, Babaei, Maryam Abbaspour, Cheah, Pike-See, Ling, King-Hwa“…Intellectual disability (ID) is one of the many features manifested in various genetic syndromes leading to deficits in cognitive function among affected individuals. …”
Publicado 2013
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1714por Lakhan, Ram“…The prevalence of psychiatric disorders was statistically higher in severely intellectually disabled children (IQ ≤ 49) than mildly intellectually disabled children (IQ ≥ 50). …”
Publicado 2013
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1715“…A human deletion mutation lacking the fourth DM14 and the adjacent C2 domain results in Non Syndromic Intellectual Disability (NSID) also referred to as Non Syndromic Mental Retardation (NSMR). …”
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1716por Ali, Afia, Scior, Katrina, Ratti, Victoria, Strydom, Andre, King, Michael, Hassiotis, Angela“…BACKGROUND: People with intellectual disability have a higher prevalence of physical health problems but often experience disparities in accessing health care. …”
Publicado 2013
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1717por Yang, Lin, Zhan, Guo-dong, Ding, Jun-jie, Wang, Hui-jun, Ma, Duan, Huang, Guo-ying, Zhou, Wen-hao“…BACKGROUND AND OBJECTIVES: Several studies have suggested a difference in clinical features of intellectual ability and psychiatric illness in the Prader–Willi syndrome (PWS) with the 15q11-q13 paternal deletion and maternal uniparental disomy (mUPD). …”
Publicado 2013
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1718por Qiao, Ying, Badduke, Chansonette, Mercier, Eloi, Lewis, Suzanne ME, Pavlidis, Paul, Rajcan-Separovic, Evica“…It has been recently shown that genomic copy number variations (CNVs) can cause aberrant expression of integral miRNAs and their target genes, and contribute to intellectual disability (ID). RESULTS: To better understand the CNV-miRNA relationship in ID, we investigated the prevalence and function of miRNAs and miRNA target genes in five groups of CNVs. …”
Publicado 2013
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1719“…The aim of this study is to analyse the differences in muscle activity between subjects who have intellectual disability and healthy subjects when they make the transition from sitting to standing positions. …”
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1720por Woodson, James C.“…METHODS: This theoretical review article identifies three factors: 1) good intentions with regard to the argument from immutability; 2) false dichotomies limiting intellectual progress by oversimplification of theory and thus hypothesis, and most dangerously, interpretation and; 3) Tradition: a historical separation of the disciplines of biology and psychology, which, to this day, interferes with the effective translation of well-conducted science into good public understanding and policy. …”
Publicado 2012
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