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  1. 18781
    “…This treatment was compared with the Italian standard therapy, consisting in the oral administration of 329.7 mg of ferrous sulfate once a day (corresponding to 105 mg of elemental iron). …”
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    Efficacy of Lactoferrin Oral Administration in the Treatment of Anemia and Anemia of Inflammation in Pregnant and Non-pregnant Women: An Interventional Study
  2. 18782
    “…O96:H19 strain 52.1 carries three plasmids, the invasion plasmid (pINV) contains all type 3 secretion system (TTSS) and TTSS effectors genes previously described for Shigella and EIEC O96:H19 CFSAN029787 Italian strain. Non-TTSS virulence genes were also identified, including: long polar fimbrial gene (IpfA), enterotoxin (senB), and antibiotic resistance genes. …”
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    1127. Genomic Analysis of Biofilm-Forming Enteroinvasive E. coli Emergent Pathogen
  3. 18783
    “…METHODS: A total of 4284 patients affected by T1DM followed-up at 76 diabetes centers participating to the Italian Association of Clinical Diabetologists (Associazione Medici Diabetologi, AMD) initiative constitutes the study population. …”
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    Association of kidney disease measures with risk of renal function worsening in patients with type 1 diabetes
  4. 18784
    “…RESULTS: We first estimated that our study had 92% power at p < 0.05 to detect a genetic effect size of 2.05 in the RT tears (93 individuals) and healthy population (206 individuals) cohorts, assuming a minor allele frequency for col5a1 variant rs12722 of 0.5707 in the Italian population (gnomAD frequency). No significant difference in allele and genotype frequencies was observed between RT tears patients and healthy controls. …”
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    Genetics of rotator cuff tears: no association of col5a1 gene in a case-control study
  5. 18785
    “…METHODS: This study was a cross-sectional analysis of the baseline questionnaire, applied from 2005 to 2016, of the Italian NINFEA (Nascita e Infanzia: gli Effetti dell’Ambiente) birth cohort. …”
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    Questionnaire Breakoff and Item Nonresponse in Web-Based Questionnaires: Multilevel Analysis of Person-Level and Item Design Factors in a Birth Cohort
  6. 18786
    “…Identification codes of patients were entered in the Italian National Health System Lumbardy database, that contains life status, causes of death, as well as exemptions, prescriptions, and hospital admissions (proxies of diseases) from visit 1 to June 2018. …”
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    A 23-year study of mortality and development of co-morbidities in patients with obesity undergoing bariatric surgery (laparoscopic gastric banding) in comparison with medical treatment of obesity
  7. 18787
    “…In this study, a sub-cohort consisting in 212 subjects (pre-frail and non-frail) from the Italian and Polish centers were selected for untargeted serum metabolomics at T0 (baseline) and T1 (follow-up). …”
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    Identification of Pre-frailty Sub-Phenotypes in Elderly Using Metabolomics
  8. 18788
    “…BACKGROUND AND AIMS: We investigated the conditioning roles of viral tropism and other variables on plasma HIV RNA levels after 6 months of combination antiretroviral therapy (cART) in an HIV-infected Italian naïve population using regression tree, random forest regression, and path analysis (PA). …”
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    Role of pretreatment variables on plasma HIV RNA value at the sixth month of antiretroviral therapy including all first line drugs in HIV naïve patients: A path analysis approach
  9. 18789
    “…This possibility is reserved for individual farmers or co-operatives, registered in the company register according to Article 8 of the Law 29th December 1993 No. 580 (Italian Republic, 1993); who may sell directly inside and outside farm, products coming mainly from the respective farms, observing the current regulations regarding health and hygiene. …”
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    Farm products’ direct sale in accordance with national and EC Regulations
  10. 18790
    por Vitale, Antonio, Cavalli, Giulio, Colafrancesco, Serena, Priori, Roberta, Valesini, Guido, Argolini, Lorenza Maria, Baldissera, Elena, Bartoloni, Elena, Cammelli, Daniele, Canestrari, Giovanni, Sota, Jurgen, Cavallaro, Elena, Massaro, Maria Grazia, Ruscitti, Piero, Cipriani, Paola, De Marchi, Ginevra, De Vita, Salvatore, Emmi, Giacomo, Ferraccioli, Gianfranco, Frassi, Micol, Gerli, Roberto, Gremese, Elisa, Iannone, Florenzo, Lapadula, Giovanni, Lopalco, Giuseppe, Manna, Raffaele, Mathieu, Alessandro, Montecucco, Carlomaurizio, Mosca, Marta, Piazza, Ilaria, Piga, Matteo, Pontikaki, Irene, Romano, Micol, Rossi, Silvia, Rossini, Maurizio, Silvestri, Elena, Stagnaro, Chiara, Talarico, Rosaria, Tincani, Angela, Viapiana, Ombretta, Vitiello, Gianfranco, Galozzi, Paola, Sfriso, Paolo, Gaggiano, Carla, Rigante, Donato, Dagna, Lorenzo, Giacomelli, Roberto, Cantarini, Luca
    Publicado 2019
    “…Methods: AOSD patients classified according with Yamaguchi criteria and treated with ANA were retrospectively enrolled in 18 Italian tertiary Centers. Demographic, laboratory, clinical and therapeutic data related to the start of ANA (baseline), the 3-month assessment and the last follow-up visit while on ANA treatment were retrospectively collected and statistically analyzed. …”
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    Long-Term Retention Rate of Anakinra in Adult Onset Still’s Disease and Predictive Factors for Treatment Response
  11. 18791
    “…Purpose: To investigate the implications of the introduction of two hormonal therapies, abiraterone acetate + prednisone (AA+P) and enzalutamide (ENZA), for the treatment of naïve patients with metastatic castration-resistant prostate cancer (mCRPC) in the Italian setting. Methods: In 2017–2018, a Health Technology Assessment was conducted in Italy, considering the National Healthcare Service (NHS) perspective. …”
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    HTA and innovative treatments evaluation: the case of metastatic castration-resistant prostate cancer
  12. 18792
    “…The phylogenetic trees revealed relatedness between the VP7 and VP4 genes of the G3P[8] RVA Italian strain (namely PG2) and those belonging to recent G3P[8] RVAs detected worldwide. …”
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    First detection of a reassortant G3P[8] rotavirus A strain in Italy: a case report in an 8-year-old child
  13. 18793
    “…Two other HCRTR2 gene variants, rs2653342 and rs2653349, have been reported to be linked to cluster headache in an Italian study. METHODS: We genotyped a total of 517 patients diagnosed with cluster headache and 581 controls, representing a general Swedish population, for rs3122156, rs2653342, and rs2653349 using quantitative real‐time PCR. …”
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    Analysis of HCRTR2 Gene Variants and Cluster Headache in Sweden
  14. 18794
    “…Previous studies of Swiss Gruyère and selected Italian hard cheeses, mostly based on amplicon metagenomics, concurred that three species generally pre-dominate: Streptococcus thermophilus, Lactobacillus helveticus and Lactobacillus delbrueckii. …”
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    Long-read based de novo assembly of low-complexity metagenome samples results in finished genomes and reveals insights into strain diversity and an active phage system
  15. 18795
    “…I281T (Chinese and Greek), A310G (Brazilian and African American), and R385* (Italian and North African) were reported across different ethnicities. …”
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    Genotypic and phenotypic spectra of hemojuvelin mutations in primary hemochromatosis patients: a systematic review
  16. 18796
    “…The survey was again conducted in 2016 in 28 delivery wards in Piedmont and the Aosta Valley in order to evaluate organizational improvements introduced after ministerial indications and recommendations by the Italian Society of Neonatology were published in 2014, in light of new findings regarding the phenomenon. …”
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    Skin-to-skin contact and delivery room practices: a longitudinal survey conducted in Piedmont and the Aosta Valley
  17. 18797
    “…METHODS: According to the Italian ministerial guidelines for direct-acting-antivirals treatment, 1022 consecutive HCV patients treated with direct-acting-antivirals were enrolled. …”
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    Incidence and risk factors of early HCC occurrence in HCV patients treated with direct acting antivirals: a prospective multicentre study
  18. 18798
    por Solari, Alessandra, Giovannetti, Ambra Mara, Giordano, Andrea, Tortorella, Carla, Torri Clerici, Valentina, Brichetto, Giampaolo, Granella, Franco, Lugaresi, Alessandra, Patti, Francesco, Salvetti, Marco, Pesci, Ilaria, Pucci, Eugenio, Centonze, Diego, Danni, Maura Chiara, Bonavita, Simona, Ferraro, Diana, Gallo, Antonio, Gajofatto, Alberto, Nociti, Viviana, Grimaldi, Luigi, Grobberio, Monica, Lanzillo, Roberta, Di Giovanni, Rachele, Gregori, Silvia, Manni, Alessia, Pietrolongo, Erika, Bertagnoli, Sarah, Ronzoni, Marco, Compagnucci, Laura, Fantozzi, Roberta, Allegri, Beatrice, Arena, Sebastiano, Buscarinu, Maria Chiara, Sabattini, Loredana, Quartuccio, Maria Esmeralda, Tsantes, Elena, Confaloneri, Paolo, Tacchino, Andrea, Schiffmann, Insa, Rahn, Anne Christin, Kleiter, Ingo, Messmer Uccelli, Michele, Barabasch, Anna, Heesen, Christoph, the ManTra Project
    Publicado 2019
    “…All pre-specified needs were scored a lot or extremely important, and two prioritized needs were shared by Italian and German patients: “physiotherapy” and “active patient care involvement.” …”
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    Conversion to Secondary Progressive Multiple Sclerosis: Patient Awareness and Needs. Results From an Online Survey in Italy and Germany
  19. 18799
    “…Patients and Methods: This is a multicenter study reviewing retrospectively the medical records from 61 patients with sJIA and 76 with AOSD, all treated with ANA in 25 Italian tertiary referral centers. Results: The cumulative retention rate of ANA at 12-, 24-, 48-, and 60-month of follow-up was 74.3%, 62.9%, 49.4%, and 49.4%, respectively, without any significant differences between sJIA and AOSD patients (p = 0.164), and between patients treated in monotherapy compared with the subgroup coadministered with conventional disease-modifying antirheumatic drugs (cDMARDs) (p = 0.473). …”
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    Anakinra Drug Retention Rate and Predictive Factors of Long-Term Response in Systemic Juvenile Idiopathic Arthritis and Adult Onset Still Disease
  20. 18800
    “…The use of biosimilar or originator ESA was not a predictor of hyporesponsiveness in an outpatient setting from two large Italian areas. A better knowledge of the predictors of ESA response would allow a better anemia management to improve patients’ quality of life.…”
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    In search of potential predictors of erythropoiesis-stimulating agents (ESAs) hyporesponsiveness: a population-based study
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