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  1. 18821
    “…When compared with European populations, the highest divergence was observed with Italian population. In conclusion, we identified 4 variants in genes encoding proteases (FURIN, PLG and PRSS1) and 6 in genes involved in the innate immunity (MBL2 and OAS1) that might be relevant for the host response to SARS-CoV-2 infection.…”
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    Functional prediction and comparative population analysis of variants in genes for proteases and innate immunity related to SARS-CoV-2 infection
  2. 18822
    “…MATERIALS AND METHODS: In this multicentre retrospective cohort study conducted in 14 Italian centres of the Gruppo Italiano Mammella, consecutive patients undergoing first-line trastuzumab or lapatinib-based therapy were included. …”
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    Clinical outcomes of patients with breast cancer relapsing after (neo)adjuvant trastuzumab and receiving trastuzumab rechallenge or lapatinib-based therapy: a multicentre retrospective cohort study
  3. 18823
    “…METHODS: Consecutive patients with apparent early-stage USC surgically treated at six Italian referral cancer centers were analyzed. A comparison was made between patients who underwent retroperitoneal staging including at least pelvic lymphadenectomy “LND” vs. those who underwent hysterectomy alone “NO-LND”. …”
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    Survival implication of lymphadenectomy in patients surgically treated for apparent early-stage uterine serous carcinoma
  4. 18824
    “…Limited real-world data on its effectiveness and safety are available from an Italian population. RESEARCH DESIGN AND METHODS: We evaluated long-term clinical data from the single-arm PERsistent Sitagliptin Treatment & Outcomes (PERS&O) study, which collected information on 440 patients with TD2 (275 men, 165 women; mean age 64.1 years; disease median duration: 12 years) treated with sitagliptin ‘add-on’. …”
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    PERsistent Sitagliptin treatment & Outcomes (PERS&O 2.0) study, long-term results: a real-world observation on DPP4-inhibitor effectiveness
  5. 18825
    “…CONCLUSIONS: Identification of the peculiar SARS-CoV-2 GZ69 strain in the late Italian epidemic highlights the need to better characterize viral variants circulating among asymptomatic or paucisymptomatic individuals. …”
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    A persistently replicating SARS-CoV-2 variant derived from an asymptomatic individual
  6. 18826
    “…Our aim was to evaluate the prognostic and/or predictive capacity of the MII in the randomized ITACa (Italian Trial in Advanced Colorectal Cancer) study on patients with metastatic colorectal cancer undergoing first-line chemotherapy. …”
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    Prognostic role of a new index (multi inflammatory index) in patients with metastatic colorectal cancer: results from the randomized ITACa trial
  7. 18827
    “…Two hundred fifty-two patients, median age 45.1 years (1.6–73.4), were enrolled from 34 Italian transplant centers. The underlying disease was acute myeloid leukemia in 180 cases (71%). …”
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    Donor Lymphocyte Infusions After Allogeneic Stem Cell Transplantation in Acute Leukemia: A Survey From the Gruppo Italiano Trapianto Midollo Osseo (GITMO)
  8. 18828
    “…The minimum spanning tree using 1,121 global MLST profiles showed specific Italian clusters and a clear separation between pig and wild boar profiles. …”
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    Genotyping and Antibiotic Resistance Traits in Campylobacter jejuni and coli From Pigs and Wild Boars in Italy
  9. 18829
    “…Hydraulic niche descriptors of final instar larvae of nine Drusus species (Trichoptera) were studied in small, spring-fed, first-order headwaters located in the Mühlviertel (Upper Austria), Koralpe (Carinthia, Austria), and in the Austrian and Italian Alps. The species investigated covered all three clades of Drusinae: the shredder clade (Drusus franzi, D. alpinus), the grazer clade (D. biguttatus, D. chauvinianus, D. dudor, D. monticola), and the filtering carnivore clade (D. chrysotus, D. katagelastos, D. muelleri). …”
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    Hydraulic niche utilization by larvae of the three Drusinae clades (Insecta: Trichoptera)
  10. 18830
    “…Here we assessed calcium metabolism in an Italian population of sarcoidosis patients, which included a group with stage IV fibrotic disease, and compared the results with those of idiopathic pulmonary fibrosis (IPF) and chronic hypersensitivity pneumonitis (cHP) patients. …”
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    Hypercalciuria in Sarcoidosis: A Specific Biomarker With Clinical Utility
  11. 18831
    “…The authors recently encountered a case of a 60-year old Italian man presenting with confusion, language disturbances and Parkinson-like syndrome 3 weeks after complete remission from severe Plasmodium falciparum cerebral malaria. …”
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    Clinical presentation and immunological features of Post-Malaria Neurologic Syndrome: a case report and review of literature
  12. 18832
    “…CareToy, already used with pre-terms without brain injury, has been adapted for high-risk infants in a project funded by the Italian Ministry of Health, and the CareToy-Revised (CareToy-R) has been realized (Trial registration: NCT03211533 and NCT03234959). …”
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    Feasibility Analysis of CareToy-Revised Early Intervention in Infants at High Risk for Cerebral Palsy
  13. 18833
    “…The Martina Franca donkey (MFd) is one of the largest Italian donkey breeds, considered as endangered breed. …”
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    Reference Ranges for Hematological and Biochemical Profile of Martina Franca Donkeys
  14. 18834
    “…The clinical trial was also registered as a post-market study at the Italian Ministry of Health.…”
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    User-centred assistive SystEm for arm Functions in neUromuscuLar subjects (USEFUL): a randomized controlled study
  15. 18835
    “…In Italy, there has been a focus of E. multilocularis since 1997 in the northern Italian Alps, later confirmed in red foxes collected from 2001 to 2005. …”
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    Echinococcus multilocularis and other cestodes in red foxes (Vulpes vulpes) of northeast Italy, 2012–2018
  16. 18836
    por Pighin, Stefania, Tentori, Katya
    Publicado 2021
    “…SETTING: Italy during the April 2020 lockdown. PARTICIPANTS: 566 Italian residents. MAIN OUTCOME MEASURES: Participants’ estimates of the SARS-CoV-2 prevalence; the predictive and diagnostic accuracy of the test; the behavioural impact of (positive vs negative) test results; the perceived usefulness of a short-term repetition of the test following positive or negative results; and rankings of causes for false positives and false negatives. …”
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    Public’s understanding of swab test results for SARS-CoV-2: an online behavioural experiment during the April 2020 lockdown
  17. 18837
    “…The high frequency of this mutation observed in Italian Ae. albopictus populations should serve as a warning bell, advocating for increased monitoring and management of a phenomenon which risks neutralizing the only weapon today available to counteract (risks of) arbovirus outbreaks.…”
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    A Novel Allele Specific Polymerase Chain Reaction (AS-PCR) Assay to Detect the V1016G Knockdown Resistance Mutation Confirms Its Widespread Presence in Aedes albopictus Populations from Italy
  18. 18838
    “…K10 cross-validation (90% training: 10% testing) protocol on an Italian cohort of 100 CoP and 30 NCoP patients was used for performance evaluation and bispectrum analysis for CT lung characterisation. …”
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    Six artificial intelligence paradigms for tissue characterisation and classification of non-COVID-19 pneumonia against COVID-19 pneumonia in computed tomography lungs
  19. 18839
    “…Data from the following assessments have been retrieved from patient charts: one-dimensional Raven test (RCPM), to evaluate cognitive development (IQ); ALS Severity Score (ALSSS) to evaluate speech disturbances; Brown Bellugy modified for Italian standards (TCGB) to evaluate language comprehension; and Children’s Hospital of Philadelphia Infant Test of Neuromuscular Disorders (CHOP-INTEND) to assess motor functioning. …”
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    Intellectual abilities, language comprehension, speech, and motor function in children with spinal muscular atrophy type 1
  20. 18840
    “…The study will involve 12 Italian intensive care units and 356 patients will be enrolled. …”
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    Adjunctive IgM-enriched immunoglobulin therapy with a personalised dose based on serum IgM-titres versus standard dose in the treatment of septic shock: a randomised controlled trial (IgM-fat trial)
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