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  1. 18841
    “…Data from the following assessments have been retrieved from patient charts: one-dimensional Raven test (RCPM), to evaluate cognitive development (IQ); ALS Severity Score (ALSSS) to evaluate speech disturbances; Brown Bellugy modified for Italian standards (TCGB) to evaluate language comprehension; and Children’s Hospital of Philadelphia Infant Test of Neuromuscular Disorders (CHOP-INTEND) to assess motor functioning. …”
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    Intellectual abilities, language comprehension, speech, and motor function in children with spinal muscular atrophy type 1
  2. 18842
    “…The study will involve 12 Italian intensive care units and 356 patients will be enrolled. …”
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    Adjunctive IgM-enriched immunoglobulin therapy with a personalised dose based on serum IgM-titres versus standard dose in the treatment of septic shock: a randomised controlled trial (IgM-fat trial)
  3. 18843
    “…CASE PRESENTATION: 17-years Italian Saddle Horse with respiratory distress and fever was admitted to the Veterinary Teaching Hospital of the Department of Veterinary Medical Sciences, University of Bologna. …”
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    First isolation of Klebsiella variicola from a horse pleural effusion
  4. 18844
    “…OBJECTIVES: To evaluate in a multicentric Italian cohort of patients with psoriatic arthritis (PsA) on secukinumab followed for 24 months: (1) the long-term effectiveness and safety of secukinumab, (2) the drug retention rate and minimal disease activity (MDA), (3) differences in the outcomes according to the biological treatment line: biologic-naïve patients (group A) versus multifailure (group B) patients. …”
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    Effectiveness and safety of secukinumab in 608 patients with psoriatic arthritis in real life: a 24-month prospective, multicentre study
  5. 18845
    “…Two SNPs (g.7539G>C and g.14067A>G) were genotyped in 747 Italian buffaloes, and major alleles had a relative frequency of 0.83 and 0.51, respectively. …”
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    Complete CSN1S2 Characterization, Novel Allele Identification and Association With Milk Fatty Acid Composition in River Buffalo
  6. 18846
    “…SETTING: Monocentric, Italian, third-level university hospital. PARTICIPANTS: All the employees of the hospital on a voluntary base, for a total of 4055 participants among 4572 HCWs (88.7%). …”
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    Seroprevalence of anti-SARS-CoV-2 IgG among healthcare workers of a large university hospital in Milan, Lombardy, Italy: a cross-sectional study
  7. 18847
    por D’Amato, Daphne, De Vincentis, Antonio, Malinverno, Federica, Viganò, Mauro, Alvaro, Domenico, Pompili, Maurizio, Picciotto, Antonino, Palitti, Valeria Pace, Russello, Maurizio, Storato, Silvia, Pigozzi, Marie Graciella, Calvaruso, Vincenza, De Gasperi, Elisabetta, Lleo, Ana, Castellaneta, Antonino, Pellicelli, Adriano, Cazzagon, Nora, Floreani, Annarosa, Muratori, Luigi, Fagiuoli, Stefano, Niro, Grazia Anna, Feletti, Valentina, Cozzolongo, Raffaele, Terreni, Natalia, Marzioni, Marco, Pellicano, Rinaldo, Pozzoni, Pietro, Baiocchi, Leonardo, Chessa, Luchino, Rosina, Floriano, Bertino, Gaetano, Vinci, Maria, Morgando, Anna, Vanni, Ester, Scifo, Gaetano, Sacco, Rodolfo, D’Antò, Maria, Bellia, Valentina, Boldizzoni, Roberto, Casella, Silvia, Omazzi, Barbara, Poggi, Guido, Cristoferi, Laura, Gerussi, Alessio, Ronca, Vincenzo, Venere, Rosanna, Ponziani, Francesca, Cannavò, Maria, Mussetto, Alessandro, Fontana, Rosanna, Losito, Francesco, Frazzetto, Evelise, Distefano, Marco, Colapietro, Francesca, Labanca, Sara, Marconi, Giulia, Grassi, Giuseppe, Galati, Giovanni, O’Donnell, Sarah Elizabeth, Mancuso, Clara, Mulinacci, Giacomo, Palermo, Andrea, Claar, Ernesto, Izzi, Antonio, Picardi, Antonio, Invernizzi, Pietro, Carbone, Marco, Vespasiani-Gentilucci, Umberto
    Publicado 2021
    “…METHODS: Patients were recruited into the Italian PBC Registry, a multicentre, observational cohort study that monitors patients with PBC at national level. …”
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    Real-world experience with obeticholic acid in patients with primary biliary cholangitis
  8. 18848
    “…Participants also completed a newly developed COVID-19 Student Stress Scale, based on transactional models of stress, and the Coping Orientation to Problems Experienced—New Italian Version (COPE-NIV) to assess coping orientation. …”
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    Further to the Left: Stress-Induced Increase of Spatial Pseudoneglect During the COVID-19 Lockdown
  9. 18849
    “…We used a multidisciplinary approach to investigate the death due to avian malaria, occurred between 2015 and 2019, in eight African penguins (Spheniscus demersus) kept in two Italian zoos located in central Italy, and situated about 30 km apart. …”
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    Plasmodium matutinum Transmitted by Culex pipiens as a Cause of Avian Malaria in Captive African Penguins (Spheniscus demersus) in Italy
  10. 18850
    “…BACKGROUND: This paper describes the clinical practice and performance of cell-free DNA sequencing-based non-invasive prenatal testing (NIPT) as a screening method for fetal trisomy 21, 18, and 13 (T21, T18, and T13) and sex chromosome aneuploidies (SCA) in a general Italian pregnancy population. METHODS: The AMES-accredited laboratory offers NIPT in maternal blood as a screening test for fetal T21, T18, T13 and SCA. …”
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    Performance of cell-free DNA sequencing-based non-invasive prenatal testing: experience on 36,456 singleton and multiple pregnancies
  11. 18851
    “…METHODS: Retrospective, multicentre, national cohort study conducted between February 24 and June 14, 2020, in 24 Italian Intensive Care Units (ICU) on adult patients needing invasive mechanical ventilation for respiratory failure caused by COVID-19. …”
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    Prone position in intubated, mechanically ventilated patients with COVID-19: a multi-centric study of more than 1000 patients
  12. 18852
    “…The prevalence of idiopathic oligozoospermia has been esteemed as high as 75%. An Italian survey has reported bilateral testicular hypotrophy in 14% of final-year high school students. …”
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    Testicular Growth and Pubertal Onset in GH-Deficient Children Treated With Growth Hormone: A Retrospective Study
  13. 18853
    “…The approach consisted in: (1) estimating the total number of asthma patients in Italy (using 2016–2017 Italian-adapted Global Initiative for Asthma -GINA- guidelines); (2) estimating the number of severe asthma patients with poorly controlled or uncontrolled disease (using the findings of two recent administrative claim analyses conducted in Italy); (3) stratifying the severe uncontrolled population by biomarker levels (EOS, FeNO and IgE) according to the outcomes of the QUEST trial (a clinical study assessing the efficacy of dupilumab in patients with uncontrolled moderate-to-severe asthma; NCT02414854); (4) identifying the sub-populations of severe uncontrolled asthma patients characterised by raised blood EOS and/or FeNO level (thus indicated to receive dupilumab). …”
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    Defining type 2 asthma and patients eligible for dupilumab in Italy: a biomarker-based analysis
  14. 18854
    “…All HCWs were asked to be vaccinated by the Italian national vaccine campaign at the beginning of 2021. 260 vaccinated HCWs were enrolled in the study. …”
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    Initial observations on age, gender, BMI and hypertension in antibody responses to SARS-CoV-2 BNT162b2 vaccine
  15. 18855
    “…METHODS: The study includes a discovery stage based on the analysis of whole exome data from 26 dominant late onset PD families, a validation analysis performed on 1542 independent PD patients and 706 controls from different cohorts and the assessment of polygenic variants load in the Italian cohort (394 unrelated patients and 203 controls). …”
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    Identification of sixteen novel candidate genes for late onset Parkinson’s disease
  16. 18856
    “…METHODS: 287 eligible patients were retrospectively collected from 16 Italian referral centers adhering to the MeetUro association. …”
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    Impact of Previous Nephrectomy on Clinical Outcome of Metastatic Renal Carcinoma Treated With Immune-Oncology: A Real-World Study on Behalf of Meet-URO Group (MeetUro-7b)
  17. 18857
    “…METHODS: It was conducted a retrospective analysis of all the judgments issued by the Public Prosecutor’s Office at a Court of a Metropolitan Italian city regarding sexual and domestic violence, from January 1(st) 2011 to 31st December 31(st) 2015. …”
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    Sexual assault and abuse committed against family members: An analysis of 1342 legal outcomes and their motivations
  18. 18858
    “…METHODS: This was a multicentre retrospective cohort study of adult patients with acute severe ulcerative colitis admitted to Italian inflammatory bowel disease referral centres from 2005 to 2017. …”
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    Long‐term outcomes of acute severe ulcerative colitis in the rescue therapy era: A multicentre cohort study
  19. 18859
    “…RESULTS: PA patterns differed between the European countries investigated, with Swedish children being most active and Italian children least active. Moderate intensity physical activity was associated with lower insulin resistance (R(2) = 2.8%), while vigorous intensity physical activity was associated with lower body mass index (R(2) = 3.6%), MetS score (R(2) = 3.1%) and higher high-density lipoprotein cholesterol (R(2) = 2.3%). …”
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    High-intensity activity is more strongly associated with metabolic health in children compared to sedentary time: a cross-sectional study of the I.Family cohort
  20. 18860
    “…METHODS: Data were retrospectively collected from clinical records of mUC patients whose disease progressed to anti-programmed death 1 (PD-1)or programmed death ligand 1 (PD-L1) therapy at 14 Italian centers. Patients were grouped according to ICI therapy setting into SALVAGE (ie, ICI delivered ⩾ second-line therapy after platinum-based chemotherapy) and NAÏVE (ie, first-line therapy) groups. …”
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    Clinical Outcomes of Patients With Metastatic Urothelial Carcinoma After Progression to Immune Checkpoint Inhibitors: A Retrospective Analysis by the Meet-Uro Group (Meet-URO 1 Study)
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