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381“…In addition, miR-26b was found to suppress cell migration and invasion via mediating JAG1 expression, which impact is partially reversed by JAG1. …”
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382“…The glume opening phenotype cosegregated with SNP (Chr1:1522703), which was located at the start codon of one transcript of OsJAG, resulting in partial loss of OsJAG function. cDNA analysis revealed that OsJAG encodes two transcript variants. …”
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383por Liebler, Sven S., Feldner, Anja, Adam, M. Gordian, Korff, Thomas, Augustin, Hellmut G., Fischer, Andreas“…There is evidence that also Notch ligands (DLL1, DLL4, JAG1, JAG2) are processed upon receptor binding to influence transcription in the ligand-expressing cell. …”
Publicado 2012
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384por Chen, Fengjiao, Yang, Ying, Chen, Jianling, Tang, Zihua, Peng, Qian, Wang, Jinfu, Ding, Jie“…Subsequently, pAJ-U6-shRNA-CMV-Puro/GFP recombinant lentiviral vectors encoding short hairpin RNAs were used to silence JAG-1, JAG-2, and DLL-1, according to the temporal expression pattern of Notch ligands. …”
Publicado 2021
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385por Tsai, Ellen A., Gilbert, Melissa A., Grochowski, Christopher M., Underkoffler, Lara A., Meng, He, Zhang, Xiaojie, Wang, Michael M., Shitaye, Hailu, Hankenson, Kurt D., Piccoli, David, Lin, Henry, Kamath, Binita M., Devoto, Marcella, Spinner, Nancy B., Loomes, Kathleen M.“…BACKGROUND & AIMS: Alagille syndrome is an autosomal-dominant, multisystem disorder caused primarily by mutations in JAG1, resulting in bile duct paucity, cholestasis, cardiac disease, and other features. …”
Publicado 2016
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386por Yang, Rong-Hua, Qi, Shao-Hai, Shu, Bin, Ruan, Shu-Bin, Lin, Ze-Peng, Lin, Yan, Shen, Rui, Zhang, Feng-Gang, Chen, Xiao-Dong, Xie, Ju-Lin“…In addition, we observed that Jag1 was high expressed in ESCs. Overexpression of Jag1 promotes ESCs migration, whereas knockdown Jag1 resulted in a significant reduction in ESCs migration in vitro. …”
Publicado 2016
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387por Murata, Akihiko, Yoshino, Miya, Hikosaka, Mari, Okuyama, Kazuki, Zhou, Lan, Sakano, Seiji, Yagita, Hideo, Hayashi, Shin-Ichi“…We here investigated whether this adhesion function was conserved in the diversified mammalian Notch ligands consisted of two families, Delta-like (Dll1, Dll3 and Dll4) and Jagged (Jag1 and Jag2). The forced expression of mouse Dll1, Dll4, Jag1, and Jag2, but not Dll3, on stromal cells induced the rapid and enhanced adhesion of cultured mast cells (MCs). …”
Publicado 2014
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388por McPhillie, Martin J., Zhou, Ying, Hickman, Mark R., Gordon, James A., Weber, Christopher R., Li, Qigui, Lee, Patty J., Amporndanai, Kangsa, Johnson, Rachel M., Darby, Heather, Woods, Stuart, Li, Zhu-hong, Priestley, Richard S., Ristroph, Kurt D., Biering, Scott B., El Bissati, Kamal, Hwang, Seungmin, Hakim, Farida Esaa, Dovgin, Sarah M., Lykins, Joseph D., Roberts, Lucy, Hargrave, Kerrie, Cong, Hua, Sinai, Anthony P., Muench, Stephen P., Dubey, Jitender P., Prud'homme, Robert K., Lorenzi, Hernan A., Biagini, Giancarlo A., Moreno, Silvia N., Roberts, Craig W., Antonyuk, Svetlana V., Fishwick, Colin W. G., McLeod, Rima“…Moreover, JAG21 treatment leads to 100% survival. Further, JAG21 is efficacious against drug-resistant Plasmodium falciparum in vitro. …”
Publicado 2020
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389por González-Reig, Santiago, Ripoll, Juan José, Vera, Antonio, Yanofsky, Martin F., Martínez-Laborda, Antonio“…The Arabidopsis fruit mainly consists of a mature ovary that shows three well defined territories that are pattern elements along the mediolateral axis: the replum, located at the medial plane of the flower, and the valve and the valve margin, both of lateral nature. JAG/FIL activity, which includes the combined functions of JAGGED (JAG), FILAMENTOUS FLOWER (FIL), and YABBY3 (YAB3), contributes to the formation of the two lateral pattern elements, whereas the cooperating genes BREVIPEDICELLUS (BP) and REPLUMLESS (RPL) promote replum development. …”
Publicado 2012
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390por Yang, Gangqiang, Ishimaru, Yasuhiro, Hoshino, Shunji, Muraoka, Yuki, Uozumi, Nobuyuki, Ueda, Minoru“…Recently, 12-hydroxyjasmonic acid glucoside (JAG) was identified as an endogenous chemical factor causing leaf-folding of S. saman. …”
Publicado 2022
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391por Hankeova, Simona, Van Hul, Noemi, Laznovsky, Jakub, Verboven, Elisabeth, Mangold, Katrin, Hensens, Naomi, Adori, Csaba, Verhoef, Elvira, Zikmund, Tomas, Dawit, Feven, Kavkova, Michaela, Salplachta, Jakub, Sjöqvist, Marika, Johansson, Bengt R, Hassan, Mohamed G, Fredriksson, Linda, Baumgärtel, Karsten, Bryja, Vitezslav, Lendahl, Urban, Jheon, Andrew, Alten, Florian, Fahnehjelm, Kristina Teär, Fischler, Björn, Kaiser, Jozef, Andersson, Emma R“…Spontaneous bleeds are a leading cause of death in the pediatric JAG1‐related liver disease Alagille syndrome (ALGS). …”
Publicado 2022
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392“…BACKGROUND: Alagille syndrome is a developmental disorder caused predominantly by mutations in the Jagged1 (JAG1) gene, which encodes a ligand for Notch family receptors. …”
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393por Matoba, Keiichiro, Kawanami, Daiji, Nagai, Yosuke, Takeda, Yusuke, Akamine, Tomoyo, Ishizawa, Sho, Kanazawa, Yasushi, Yokota, Tamotsu, Utsunomiya, Kazunori“…Mechanistically, Rho-kinase regulated Jag1 induction via the extracellular signal-regulated kinase (ERK) 1/2 and c-Jun N-terminal kinase (JNK) but not Smad pathways. …”
Publicado 2017
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395por Tanaka, Tomonari, Zhou, Yiting, Tamoto, Chihiro, Kurebayashi, Yuuki, Takahashi, Tadanobu, Suzuki, TakashiEnlace del recurso
Publicado 2017
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398“…The apoptotic rate was measured with flow cytometry and Jag2/Notch2/hes1 mRNA, and the protein expression was measured for 1, 3 and 7 days. …”
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399por Sayama, Takashi, Tanabata, Takanari, Saruta, Masayasu, Yamada, Testsuya, Anai, Toyoaki, Kaga, Akito, Ishimoto, Masao“…However, whether Gm-JAG1 is responsible for those traits in soybean is not yet known. …”
Publicado 2017
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