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Mostrando 41 - 60 Resultados de 1,374 Para Buscar '"JAG"', tiempo de consulta: 0.21s Limitar resultados
  1. 41
    por Portolan, Lisa, McAlister, Jodi
    Publicado 2021
    “…We propose that participants use of dating apps in this period was characterised by ‘jagged love’, which we have theorised in relation to Zygmunt Bauman’s notion of ‘liquid love’. …”
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    Jagged Love: Narratives of Romance on Dating Apps during COVID-19
  2. 42
    “…OBJECTIVE: Portal mesenchymal cells induce the epithelial differentiation of the bile ducts in the developing liver via one of the Delta-Notch signaling components, JAGGED1. Although this differential induction is crucial for normal liver physiology as its genetic disorder (Alagille syndrome) causes jaundice, the molecular mechanism behind JAGGED1 expression remains unknown. …”
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    Identifying potential regulators of JAGGED1 expression in portal mesenchymal cells
  3. 43
    por Jag Mohan
    Publicado 2003
    Libro
    Organic analytical chemistry : theory and practice /
  4. 44
    “…Pathogenic variants in JAG1 are known to cause Alagille syndrome (ALGS), a disorder that primarily affects the liver, lung, kidney, and skeleton. …”
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    Isolated aneurysmal disease as an underestimated finding in individuals with JAG1 pathogenic variants
  5. 45
    “…RESULTS: We determined the (1)H-NMR solution structure of the polypeptide encoded by exon 6 of JAG1 and spanning the C-terminal region of EGF1 and the entire EGF2. …”
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    Exon 6 of human JAG1 encodes a conserved structural unit
  6. 46
    “…Importantly, CD4(+) T cells from CD46-deficient patients and patients with hypomorphic Jagged1 mutations (Alagille Syndrome) fail to mount appropriate T(H)1 responses in vitro and in vivo suggesting that CD46-Jagged1 crosstalk is responsible for the recurrent infections in subpopulations of these patients.…”
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    The CD46 and Jagged1 interaction is critical for human T helper 1 immunity
  7. 47
    “…We provide evidence that Notch-specific ligand Jagged1 is a new Notch3 signaling target gene. This essential event justifies an aberrant Notch3/Jagged1 cis-expression inside the same cell. …”
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    Notch3/Jagged1 Circuitry Reinforces Notch Signaling and Sustains T-ALL()()
  8. 48
    “…JAG assigns SNPs to genes and incorporates self-contained and/or competitive tests for gene-set analysis. …”
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    JAG: A Computational Tool to Evaluate the Role of Gene-Sets in Complex Traits
  9. 49
    “…Jagged-2-RNA interference experiments suggested that Jagged-2-siRNA2 suppresses Jagged-2 expression during chondrogenic differentiation and in IFN-γ pretreated AMSCs. …”
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    Jagged-2 enhances immunomodulatory activity in adipose derived mesenchymal stem cells
  10. 50
    “…JAG1 is a Notch ligand that plays a critical role in multiple signaling pathways. …”
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    JAG1 Is Associated with Poor Survival through Inducing Metastasis in Lung Cancer
  11. 51
    “…We used mice with EC-specific deletion of the gene encoding jagged-2 (Jag2) to demonstrate that while EC-derived jagged-2 was dispensable for maintaining the capacity of HSPCs to repopulate under steady-state conditions, by activating Notch2 it did contribute to the recovery of HSPCs in response to myelosuppressive conditions. …”
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    Endothelial jagged-2 sustains hematopoietic stem and progenitor reconstitution after myelosuppression
  12. 52
    “…We found that intestinal-specific Jag1 deletion or antibody targeting Jag1 prevents tumor initiation in mice. …”
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    Manic Fringe deficiency imposes Jagged1 addiction to intestinal tumor cells
  13. 53
    “…Jagged1, the essential ligand of the Notch signalling pathway, is highly expressed in metastatic prostate cancer, and its high expression in breast cancer is linked to poor survival rates. …”
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    Role of Jagged1/STAT3 signalling in platinum‐resistant ovarian cancer
  14. 54
    “…OBJECTIVES: JAG2 is one of Notch ligands, which recently appear to exert various carcinogenesis. …”
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    Overexpression of JAG2 is related to poor outcomes in oral squamous cell carcinoma
  15. 55
    “…In pancreatic cancer patients, JAG1 expression is higher in cancerous tissue, and high JAG1 is associated with poor overall survival. …”
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    Loss of Jag1 cooperates with oncogenic Kras to induce pancreatic cystic neoplasms
  16. 56
    “…In this study, two key ligand genes of the Notch signaling pathway, delta (dl) and jagged (jag), were selected and their lethal effects and functional analysis were systematically evaluated using a stable short-winged population (Brachypterous strain) and a long-winged population (Macropterous strain) of BPHs. …”
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    Delta and jagged are candidate target genes of RNAi biopesticides for the control of Nilaparvata lugens
  17. 57
    Publicado 2009
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    Studenti Maltin qed imorru jag'mlu rierka fil-laboratorji ta-CERN
  18. 58
    “…JAG1 may be a marker for resistance of immunotherapy. …”
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    JAG1 is correlated to suppressive immune microenvironment and predicts immunotherapy resistance in lung adenocarcinoma
  19. 59
    “…Finally, Jagged 1 silencing inhibited the xenografted tumors in vivo. …”
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    Jagged 1 Regulates The Proliferation and Metastasis of Human MDA-T68 Thyroid Cancer Cells
  20. 60
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    JAG1 and THBS2 Mutations in a Child Presenting With Incomplete Alagille Syndrome
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