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  1. 1201
    por Hopfer, O, Zwahlen, D, Fey, M F, Aebi, S
    Publicado 2005
    “…The proliferation and colony formation of A2780 cells were measured after stable transfection with activated Notch 1 (intracellular domain). Jagged 2, Delta-like-1, Manic Fringe, and TSL1 were expressed more frequently in adenocarcinomas whereas Deltex, Mastermind, and Radical Fringe were more frequent in adenomas. …”
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    The Notch pathway in ovarian carcinomas and adenomas
  2. 1202
    “…RESULTS: We searched for 22 components of the Notch pathway in 35 different species that represent 8 major clades of eukaryotes, performed phylogenetic analyses and compared the domain compositions of the two fundamental molecules: the receptor Notch and its ligands Delta/Jagged. We confirm that a Notch pathway, with true receptors and ligands is specific to the Metazoa. …”
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    Origin and evolution of the Notch signalling pathway: an overview from eukaryotic genomes
  3. 1203
    “…Moreover, the alteration of chemokine (CC-motif) ligand 5, chemokine (CC-motif) ligand 20, and Jagged 1 genes, which are involved in the inflammation and enterocyte proliferation, suggested that these genes might be involved in the radiation enteropathy. …”
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    Online Artículo Texto
    Comprehensive Assessment of Host Responses to Ionizing Radiation by Nuclear Factor-κB Bioluminescence Imaging-Guided Transcriptomic Analysis
  4. 1204
    “…RESULTS: We found that Notch signaling was activated after LPS stimulation. The expression of Jagged 1, a Notch ligand, induced by LPS occurred in a JNK-dependent manner. …”
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    Lipopolysaccharide-induced Notch signaling activation through JNK-dependent pathway regulates inflammatory response
  5. 1205
    “…RESULTS: The micrographs used in this study, based on LM and SEM observations, highlight the following important identifying characters of D. gallinae: the prominent shoulders of the dorsal shield and the jagged edges of the shield reticulations, the position of setae j1, s1 and the epigynal pores, and the presence on tibia IV pl of one seta. …”
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    Online Artículo Texto
    A gallery of the key characters to ease identification of Dermanyssus gallinae (Acari: Gamasida: Dermanyssidae) and allow differentiation from Ornithonyssus sylviarum (Acari: Gamasida: Macronyssidae)
  6. 1206
    “…The T-cell subsets, mRNA expression of Delta-like1, Delta-like4, Jagged1, and Notch2 genes in the thymus were investigated. …”
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    T Cells Development Is Different between Thymus from Normal and Intrauterine Growth Restricted Pig Fetus at Different Gestational Stage
  7. 1207
    “…Compared to TGF-β and RLX co-culture alone, TGF-β + RLX + Notch inhibitor increased cell mobility and the EndMT, but decreased the levels of Notch-1, HES-1, and Jagged-1 proteins. CONCLUSION: RLX may inhibit the cardiac fibrosis via EndMT by Notch-mediated signaling.…”
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    Online Artículo Texto
    Relaxin inhibits cardiac fibrosis and endothelial–mesenchymal transition via the Notch pathway
  8. 1208
    “…At physiological E(2) concentrations the surfaces became increasingly jagged as detected by an increase in membrane height. …”
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    Variations in Cell Surfaces of Estrogen Treated Breast Cancer Cells Detected by A Combined Instrument for Far-Field and Near-Field Microscopy
  9. 1209
    “…As compared to hBM-MSCs, hBM-MSCs* showed higher level of Notch1, Jagged1 as well as the main Notch target gene HES1. …”
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    Notch signalling drives bone marrow stromal cell-mediated chemoresistance in acute myeloid leukemia
  10. 1210
    “…We constructed a three-molecule score based on the expression of Notch pathway molecules: Jagged1, intracellular Notch1 (ICN1) and Hes1 (JIH score). …”
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    Online Artículo Texto
    A three-molecule score based on Notch pathway predicts poor prognosis in non-metastasis clear cell renal cell carcinoma
  11. 1211
    “…The LRS and MRS powders are characterized by distinct, highly inhomogeneous morphologies and sizes, where LRS powder particles are highly irregular and jagged and MRS powder particles are rough, but primarily rounded. …”
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    Online Artículo Texto
    Robust and Elastic Lunar and Martian Structures from 3D-Printed Regolith Inks
  12. 1212
    “…The expressions of the Notch 1 receptor and its ligands Jagged 1 and 2 were downregulated by tangeretin. Our findings support the possible use of tangeretin for treating allergic asthma.…”
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    Tangeretin has anti-asthmatic effects via regulating PI3K and Notch signaling and modulating Th1/Th2/Th17 cytokine balance in neonatal asthmatic mice
  13. 1213
    “…RESULTS: In high-glucose (HG) conditions, miR-34a overexpression inhibited the expression of Notch 1, Jagged 1, NICD, Hes 1, and Hey 1 proteins. Further, cleaved caspase-3, Bax, and phosphorylation of p53 (p-p53) were reduced significantly. …”
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    Regulation of podocyte lesions in diabetic nephropathy via miR-34a in the Notch signaling pathway
  14. 1214
    “…The data revealed low expression levels of Notch1 receptor and its endogenous ligand Jagged1 in normal adult rat hearts. However, significantly higher expression of Notch1 was observed in the border zone compared with the infarcted area and the remote zone following myocardial IR. …”
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    Online Artículo Texto
    Simulated microgravity hampers Notch signaling in the fight against myocardial ischemia-reperfusion injury
  15. 1215
    “…A novel sintered cutting stainless steel fiber felt with internal channels (SCSSFFC) composed of a stainless-steel fiber skeleton, three-dimensional interconnected porous structure and multiple circular microchannels is developed. SCSSFFC has a jagged and rough surface morphology and possesses a high specific surface area, which is approximately 2.4 times larger than that of the sintered bundle-drawing stainless steel fiber felt with internal channels (SBDSSFFC) and is expected to enhance adhesive strength. …”
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    Fabrication and Characteristics of Sintered Cutting Stainless Steel Fiber Felt with Internal Channels and an Al(2)O(3) Coating
  16. 1216
    “…We found that the mesenchymal niche in neonatal BM, compared to adult BM, was characterized by a higher frequency of primitive subsets of mesenchymal stroma expressing both platelet-derived growth factor receptor and Sca-1, and higher expression levels of the niche cross-talk molecules, Jagged-1 and CXCL-12. Accordingly, normal HSCs transplanted into neonatal mice exhibited higher levels of regeneration in BM, with no difference in homing efficiency or splenic engraftment compared to adult BM. …”
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    Online Artículo Texto
    Age-related differences in the bone marrow stem cell niche generate specialized microenvironments for the distinct regulation of normal hematopoietic and leukemia stem cells
  17. 1217
    “…HBV cccDNA levels and relative gene expression were evaluated in HBV-replicating cells treated with Jagged1 shRNA and a γ-secretase inhibitor. The effects of these factors in surgically resected clinical samples were also assessed. …”
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    Notch signaling facilitates hepatitis B virus covalently closed circular DNA transcription via cAMP response element-binding protein with E3 ubiquitin ligase-modulation
  18. 1218
    “…A comparative transcriptomic analysis performed in cold‐sensitive and cold‐resistant strains confirms the downregulation of classical neuronal markers during aging but also shows the upregulation of putative regulators of neurotransmission and neurogenesis such as AHR, FGFR, FoxJ3, Fral2, Jagged, Meis1, Notch, Otx1, and TCF15. The switch of Fral2 expression from neurons to germ cells suggests that in aging animals, the neurogenic program active in ISCs is re‐routed to germ cells, preventing de novo neurogenesis and impacting animal survival.…”
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    Loss of Neurogenesis in Aging Hydra
  19. 1219
    “…The mRNA levels of the Notch ligands JAGGED1 and DELTA1 also increased gradually during development. …”
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    Online Artículo Texto
    The Notch system during pubertal development of the bovine mammary gland
  20. 1220
    “…This R package relies upon Just Another Gibbs Sampler (JAGS) to conduct Bayesian NMA using a generalized linear model. …”
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    Online Artículo Texto
    BUGSnet: an R package to facilitate the conduct and reporting of Bayesian network Meta-analyses
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