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  1. 1301
    “…The tendons of the diabetic group showed great irregularity in fiber bundles, including modified grain direction and jagged junctions and deformities in the form of collagen fibrils bulges. …”
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    Experimental Diabetes Alters the Morphology and Nano-Structure of the Achilles Tendon
  2. 1302
    “…Next, a generalized additive mixed model is used to help define the relationship of each remaining variable with the response variable. Using jags and rjags for the analysis of Bayesian hierarchical models using Markov Chain Monte Carlo simulation, we then developed a movement model to generate parameter estimates for each of the variables of interest. …”
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    An analytical approach to sparse telemetry data
  3. 1303
    “…Moreover, cIPC can reveal the expression peak of Jagged1, Notch1, NICD, and Hes1 protein, thereby indicating that cIPC can preactivate Notch signaling. …”
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    Neuroprotective Effects of Cerebral Ischemic Preconditioning in a Rat Middle Cerebral Artery Occlusion Model: The Role of the Notch Signaling Pathway
  4. 1304
    “…VA increased the protein expressions of Jagged-1, Notch1, NICD and HES1, and the mRNA expressions of Hes1 and Hey2, while some of the effects could be suppressed by DAPT. …”
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    Velvet Antler Mobilizes Endothelial Progenitor Cells to Promote Angiogenesis and Repair Vascular Endothelial Injury in Rats Following Myocardial Infarction
  5. 1305
    “…Genetic analysis in 206 revealed JAGGED1 mutations in 91% and NOTCH2 mutations in 4%. …”
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    Outcomes of Childhood Cholestasis in Alagille Syndrome: Results of a Multicenter Observational Study
  6. 1306
    “…The clinical outcomes including renal function indices (Scr, BUN, 24-hour urinary protein quantity) and Indicators of RIF (TGF-β1, Notch1, Jagged-1). The risk of bias included in the RCTs will be evaluated by the bias risk assessment tool provided in the Cochrane System Evaluation Manual 5.1.0. …”
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    The efficacy of taking traditional Chinese medicine orally in renal interstitial fibrosis: A protocol for a systematic review and meta-analysis
  7. 1307
    “…Furthermore, we verified that Thbs-2 can promote Notch pathway activation by directly binding to Jagged and Notch. Through in vitro experiments, we found that the expression of synaptic proteins and the number of synaptic bodies were increased in neurons in the NVU, which was constructed using astrocytes pretreated with miRNA-9-5p inhibitor. …”
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    (Downregulation of microRNA-9-5p promotes synaptic remodeling in the chronic phase after traumatic brain injury)
  8. 1308
    “…We implement these models in R using JAGS and we compare our approach to the one-stage dose–response meta-analysis model in a simulation study. …”
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    A Bayesian dose–response meta-analysis model: A simulations study and application
  9. 1309
    “…Furthermore, the Notch pathway activator Jagged-1/FC reversed the effects of palbociclib on cell proliferation, apoptosis, senescence and cell cycle progression. …”
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    Palbociclib induces cell senescence and apoptosis of gastric cancer cells by inhibiting the Notch pathway
  10. 1310
    “…Moreover, gene and protein expression of key elements of the Notch signaling pathway (Notch1, Delta-like canonical Notch ligand 4 (DLL4), Hairy Enhancer of Split-1 (Hes1), Hey1, Jagged-1), gene expression of angiogenic marker (vascular endothelial growth factor and stromal cell-derived factor 1) and epidermal stem cells (EPSCs) related gene (ß1 Integrin) were assessed. …”
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    Adipose mesenchymal stem cells combined with platelet-rich plasma accelerate diabetic wound healing by modulating the Notch pathway
  11. 1311
    por Li, Mingchen, Li, Kai, Ren, Yuan
    Publicado 2021
    “…The protein levels of MAPK signaling members (p-JNK1/2, p-ERK1/2, and p-p38) and Notch1 signaling members (Notch1, Hes 1, and Jagged 1) were detected by Western blot. RESULTS: CoCl(2) significantly promoted cell apoptosis, increased LDH leakage, MDA concentration, and decreased cell viability, SOD activity, GSH production, and CAT activity. …”
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    Nesfatin-1 protects H9c2 cardiomyocytes against cobalt chloride-induced hypoxic injury by modulating the MAPK and Notch1 signaling pathways
  12. 1312
    “…Furthermore, combination therapy increased the epidermal growth factor and Ki67‐positive cells and upregulated beta‐catenin (β‐catenin), cellular‐myelocytomatosis (c‐Myc), wingless‐type MMTV integration site family member 1 (Wnt1), Jagged 1, neurogenic locus notch homolog protein 1 (Notch 1) and hairy and enhancer of split 1 (Hes 1) protein levels of the Wnt and Notch signalling pathways. …”
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    Combination of an engineered Lactococcus lactis expressing CXCL12 with light‐emitting diode yellow light as a treatment for scalded skin in mice
  13. 1313
    “…METHODS: We conducted a subjective and objective study to compare commonly used blister packs with newly designed ones that have a jagged notch designed to hold a pill temporarily and a perforated line that enables the pack to be held easily in one hand. …”
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    Evaluation of Newly Designed Blister Packs for Easier Handling to Prevent Pill Dropping
  14. 1314
    “…We observed that pcDNA3.1(+)-CYP2J2 promoted CYP2J2 and Jagged1 expression, while Dll4 was down-regulated in hypoxia-stimulated HRVECs. …”
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    Cytochrome P450 2J2 inhibits the proliferation and angiogenesis of retinal vascular endothelial cells by regulating the Notch signaling pathway in a hypoxia-induced retinopathy model
  15. 1315
    “…Then, a pairwise meta-analysis was conducted using Stata version 13, and network meta-analysis within the Bayesian framework was conducted using R software version 3.5.3 with the package “gemtc 0.8–2” recalling JAGS (version 4.3.0). Results: Overall, 34 randomized controlled trials were included in this study. …”
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    Renal adverse reactions of tyrosine kinase inhibitors in the treatment of tumours: A Bayesian network meta-analysis
  16. 1316
    “…Reciprocally, YAP transcriptionally upregulated the Notch ligand Jagged1 gene expression and was essential for Notch1-mediated macrophage polarization. …”
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    Targeting Notch1-YAP Circuit Reprograms Macrophage Polarization and Alleviates Acute Liver Injury in Mice
  17. 1317
    “…Co-culture of ADAS cells with fibroblasts that stably expressed the Notch ligand Jagged 1 or overexpression of the Notch intracellular domain (NICD) did not alter ADAS cell growth, morphology, or cellular marker expression. …”
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    The Neuro-Glial Properties of Adipose-Derived Adult Stromal (ADAS) Cells Are Not Regulated by Notch 1 and Are Not Derived from Neural Crest Lineage
  18. 1318
    “…Results Genes more highly expressed in BRCA1-associated tumors included stathmin, osteopontin, TGFβ2 and Jagged 1 in addition to genes previously identified as characteristic of basal-like breast cancers. …”
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    Expression profiling of familial breast cancers demonstrates higher expression of FGFR2 in BRCA2-associated tumors
  19. 1319
    “…RESULTS: Microarray comparisons of human RB tumors with normal retinal tissue detected upregulation of a number of genes involved in embryonic development that were also present in Y79 cells, including Oct3/4, Nanog, Musashi-1 and Musashi-2, prominin-1 (CD133), Jagged-2, Reelin, Thy-1, nestin, Meis-1,NCAM, Patched, and Notch4. …”
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    Human embryonic and neuronal stem cell markers in retinoblastoma
  20. 1320
    por Rauner, Gat, Barash, Itamar
    Publicado 2012
    “…Of note was the high expression of Stat5a in the puPgt cells, and of Notch1, Delta1, Jagged1 and Hey1 in the puStm and Basal populations. …”
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    Cell Hierarchy and Lineage Commitment in the Bovine Mammary Gland
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