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  1. 45121
    “…PATIENTS AND METHODS: Hemodialysis patients with intractable pruritus from institutions in Japan who received oral nalfurafine hydrochloride between January 2010 and December 2013 were enrolled in the surveillance. …”
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    Post-marketing surveillance study of the safety and efficacy of nalfurafine hydrochloride (Remitch(®) capsules 2.5 μg) in 3,762 hemodialysis patients with intractable pruritus
  2. 45122
    “…RESULTS: Data from 27 published/unpublished studies from 19 countries/administrative regions – Australia, Canada, China, Finland, France, Germany, Hong Kong SAR, India, Iran, Italy, Japan, Netherlands, New Zealand, Norway, Reunion Island, Singapore, United Kingdom, United States, and Vietnam – were eligible for inclusion. …”
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    Estimating age‐specific cumulative incidence for the 2009 influenza pandemic: a meta‐analysis of A(H1N1)pdm09 serological studies from 19 countries
  3. 45123
    “…Here, we conducted a GWAS to identify common genetic variations that affected coffee consumption in a Japanese population of 11,261 participants recruited as a part of the Japan Multi-Institutional Collaborative Cohort (J-MICC) study. …”
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    A genome-wide association study in the Japanese population identifies the 12q24 locus for habitual coffee consumption: The J-MICC Study
  4. 45124
    “…FINDINGS: All patients admitted to a medical ICU at a college affiliated with the Japan Society of Intensive Care Medicine between January 2008 and December 2014 were surveyed prospectively for the development of CRBSIs. …”
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    An educational program for decreasing catheter-related bloodstream infections in intensive care units: a pre- and post-intervention observational study
  5. 45125
    “…It has a good antibacterial effect on the Gram‐negative bacteria E. coli and Salmonellae, which are difficult to control with other natural preservatives. ɛ‐Polylysine has already been used generally as a food additive in Japan, Korea and other part of world. In the United States, FDA has recognized the polylysine as a GRAS material. …”
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    Antimicrobial packaging based on ɛ‐polylysine bioactive film for the control of mycotoxigenic fungi in vitro and in bread
  6. 45126
    “…METHODS: This double‐blind clinical trial (ONO‐7643‐04) enrolled 174 patients with unresectable stage III/IV non–small cell lung cancer (NSCLC) and cachexia in Japan. Patients were randomized to daily oral anamorelin (100 mg) or a placebo for 12 weeks. …”
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    Anamorelin (ONO‐7643) for the treatment of patients with non–small cell lung cancer and cachexia: Results from a randomized, double‐blind, placebo‐controlled, multicenter study of Japanese patients (ONO‐7643‐04)
  7. 45127
    “…METHODS: This study was conducted across three medical centers in Japan. We retrospectively reviewed all patients who commenced nivolumab treatment at these centers between December 17, 2015 and July 31, 2016. …”
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    Metastatic site as a predictor of nivolumab efficacy in patients with advanced non-small cell lung cancer: A retrospective multicenter trial
  8. 45128
    “…METHODS: In this interim analysis of a phase III, open-label, multicenter extension study in Japan, South Korea, and Taiwan [ClinicalTrials.gov identifier: NCT02082249/JapiCTI-142482], the mean change from baseline to final visit in ‘off’ time, as reported in the PD symptom diary, was normalized to a 16-h waking day. …”
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    Safety and efficacy of levodopa-carbidopa intestinal gel: results from an open-label extension study in Japanese, Korean and Taiwanese patients with advanced Parkinson’s disease
  9. 45129
    “…Background: Dialysis guidelines in Japan recommend more frequent measurement of mineral metabolism markers than the Kidney Disease: Improving Global Outcomes guidelines. …”
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    Frequent monitoring of mineral metabolism in hemodialysis patients with secondary hyperparathyroidism: associations with achievement of treatment goals and with adjustments in therapy
  10. 45130
    “…OBJECTIVE: There have been no reports evaluating the physical growth in early childhood in Fukushima Prefecture after the Great East Japan Earthquake. We retrospectively investigated the health examination data in early childhood (aged 0–3 years). …”
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    Effect of the Fukushima earthquake on weight in early childhood: a retrospective analysis
  11. 45131
    “…BACKGROUND: The North-East Japan Study Group (NEJ) 005/Tokyo Cooperative Oncology Group (TCOG) 0902 study has reported that first-line concurrent and sequential alternating combination therapies of an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (gefitinib) plus platinum-based doublet chemotherapy (carboplatin/pemetrexed) offer promising efficacy with predictable toxicities for patients with EGFR-mutant non-small cell lung cancer. …”
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    Updated survival outcomes of NEJ005/TCOG0902: a randomised phase II study of concurrent versus sequential alternating gefitinib and chemotherapy in previously untreated non-small cell lung cancer with sensitive EGFR mutations
  12. 45132
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    The identification of celiac disease in asymptomatic children: the Generation R Study
  13. 45133
    “…We examined the relationship between neighborhood social capital and sleep duration by gender in adults living in a rural community in Japan. METHOD: We conducted a cross-sectional survey of 12,321 residents aged ≥20 years in a town in Mie Prefecture in January–March 2013. …”
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    Neighborhood social capital and sleep duration: a population based cross-sectional study in a rural Japanese town
  14. 45134
    “…METHOD: Participants were 357 1st year medical students from 2008 to 2011 at one medical school in Japan. Students completed self-report questionnaires comprising three validated instruments measuring EI: Trait Emotional Intelligence Questionnaire-Short Form (TEIQue-SF), empathy: Jefferson Scale of Physician Empathy- student version (JSPE) and personality: NEO-Five-Factor Inventory (NEO-FFI), which explores 5 dimensions of personality Neuroticism (N), Extraversion (E), Openness to experience (O), Agreeableness (A), and Conscientiousness (C). …”
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    Associations between emotional intelligence, empathy and personality in Japanese medical students
  15. 45135
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    Associations between clinical data and computed tomography features in patients with epidermal growth factor receptor mutations in lung adenocarcinoma
  16. 45136
    “…Therefore, fNIRS has been used as an aid for differential diagnosis of depressive symptoms as a clinical application in Japan. However, the fNIRS diagnosis system is not considered gender, age, and task performance which could be associated with brain activity. …”
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    S144. THE ASSOCIATION BETWEEN BRAIN ACTIVITY IN THE PREFRONTAL CORTEX AND DEMOGRAPHIC VARIABLES: A LARGE-SAMPLE FUNCTIONAL NEAR-INFRARED SPECTROSCOPY STUDY
  17. 45137
    “…The study proposal was reviewed and approved by NCCD, Japan and Bangladesh Medical Research Council (BMRC), Bangladesh. …”
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    Mobile-health tool to improve maternal and neonatal health care in Bangladesh: a cluster randomized controlled trial
  18. 45138
    “…PURPOSE: Due to the burden of COPD in Japan, new pharmacologic treatments are needed to meet patient requirements. …”
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    Randomized, double-blind, placebo-controlled trial to assess the efficacy and safety of three doses of co-suspension delivery technology glycopyrronium MDI in Japanese patients with moderate-to-severe COPD
  19. 45139
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    Factors influencing health-related quality of life after gastrectomy for cancer
  20. 45140
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    Multicenter phase II study of trastuzumab plus S-1 alone in elderly patients with HER2-positive advanced gastric cancer (JACCRO GC-06)
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