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45481por Huang, Daniel Q., Yeo, Yee Hui, Tan, Eunice, Takahashi, Hirokazu, Yasuda, Satoshi, Saruwatari, Junji, Tanaka, Kenichi, Oniki, Kentaro, Kam, Leslie Y., Muthiah, Mark D., Hyogo, Hideyuki, Ono, Masafumi, Barnett, Scott D., Li, Jie, Zou, Biyao, Fung, James, Lee, Teng‐Yu, Wong, Vincent Wai‐Sun, Yuen, Man‐Fung, Dan, Yock Young, Lim, Seng Gee, Cheung, Ramsey, Toyoda, Hidenori, Eguchi, Yuichiro, Nguyen, Mindie H.“…We validated our study level data with individual patient level data in 6,058 individuals from five study centers in Japan. Consistent with our study‐level data, we found that the ALT upper threshold in our individual patient data analysis was indeed higher in overweight versus normal‐weight individuals (39 vs. 32) and in diabetics versus nondiabetics (42 vs. 33). …”
Publicado 2020
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45482por Hirotsu, Yosuke, Maejima, Makoto, Shibusawa, Masahiro, Nagakubo, Yuki, Hosaka, Kazuhiro, Amemiya, Kenji, Sueki, Hitomi, Hayakawa, Miyoko, Mochizuki, Hitoshi, Tsutsui, Toshiharu, Kakizaki, Yumiko, Miyashita, Yoshihiro, Omata, Masao“…Serial dilution analysis showed a limit of detection of around 10–100 viral genome copies according to the protocol of the National Institute of Infectious Diseases, Japan. Spike-in experiments demonstrated that RT-qPCR detected positive signals in pooled samples with SARS-CoV-2-negative and -positive patients at 5-, 10-, 20-fold dilutions. …”
Publicado 2020
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45483por Raschi, Emanuel, Fusaroli, Michele, Ardizzoni, Andrea, Poluzzi, Elisabetta, De Ponti, Fabrizio“…Higher-than-expected reporting emerged for palbociclib (1.38; 1.07–1.77) and ribociclib (2.39; 1.34–3.92) only when removing Japan reports. ILD occurred at recommended daily doses, with median latency ranging from 50 (abemaciclib) to 253 (ribociclib) days. …”
Publicado 2020
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45484por Toyoshima, Akira, Nishizawa, Toshihiro, Sunami, Eiji, Akai, Ryuji, Amano, Takahiro, Yamashita, Akiyoshi, Sasaki, Shin, Endo, Takeshi, Moriya, Yoshihiro, Toyoshima, Osamu“…METHODS: This study was conducted at Department of Colorectal Surgery, Japanese Red Cross Medical Center, Tokyo, Japan, with a total of 117 patients. We enrolled 117 patients with extremely low rectal cancer who underwent laparotomic and laparoscopic ISRs at our hospital. …”
Publicado 2020
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45485por Komatsu, Katsuya, Takagi, Yasushi, Ishii, Akira, Kikuchi, Takayuki, Yamao, Yukihiro, Yoshida, Kazumichi, Miyamoto, Susumu“…The purpose of the current retrospective study was to confirm how AVM treatment in Japan has changed and to assess the safety of treatment for hemorrhagic and nonhemorrhagic AVMs. …”
Publicado 2020
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45486por Morii, Yasuhiro, Furuta, Seiichi, Ishikawa, Tomoki, Fujiwara, Kensuke, Yamashina, Hiroko, Ogasawara, Katsuhiko“…BACKGROUND: Pharmacists play an important role in promoting people’s health in Japan, which has an aging population. Hence, it is necessary that the distribution of pharmacists meets the population’s needs in each region. …”
Publicado 2020
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45487por Ikemoto, Tatsunori, Shiro, Yukiko, Ikemoto, Kayo, Hayashi, Kazuhiro, Arai, Young-Chang, Deie, Masataka, Beeston, Lee, Wood, Bradley, Nicholas, Michael“…(Pain 154(6):824–835, 2013) in Australia would be effective for elderly people with chronic pain in Japan. METHODS: Twenty-seven community-dwelling elderly people with chronic pain were enrolled to confirm changes (effect size d = 0.5) in pain disability, which were previously reported by Nicholas et al. …”
Publicado 2020
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45488por Kee, A. R., Yip , V. C. H., Tay, E. L. T., Lim, C. W., Cheng, J., Teo, H. Y., Chua, C. H., Yip , L. W. L.“…METHODS: A cross-sectional observational study was performed on healthy and glaucoma subjects, on whom two sets of OCTA images of optic disc and macula were acquired using both AngioVue (Optovue, USA) and Swept Source (Topcon, Japan) OCTA devices during one visit. A novel in-house software was used to calculate the vessel densities. …”
Publicado 2020
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45489por Li, Na, Zhou, Junming, Wang, Huan, Mu, Changkao, Shi, Ce, Liu, Lei, Wang, Chunlin“…BACKGROUND: Scylla paramamosain is one of the commercially crucial marine crustaceans belonging to the genus Scylla, which is commonly distributed along the coasts of China, Vietnam, and Japan. Genomic and transcriptomic data are scarce for the mud crab. …”
Publicado 2020
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45490“…SETTING: The target facility was a nursing home located in Japan. The researcher, a physical therapist, worked at the nursing home once a week from April 2016 to March 2017. …”
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45491“…The highest reproductive number was reported for the Diamond Princess Cruise Ship in Japan (14.8). In the country-level, the higher reproductive number was reported for France (R, 6.32, 95% CI, 5.72–6.99) following Germany (R, 6.07, 95% CI, 5.51–6.69) and Spain (R, 3.56, 95% CI, 1.62–7.82). …”
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45492por Furuhata, Ryogo, Matsumura, Noboru, Yoshiyama, Akira, Kamata, Yusaku, Takahashi, Masaaki, Morioka, Hideo“…The results of this study indicated that the onset of calcium resorption occurs most frequently in the summer in Japan; however, the reasons for seasonal variation remain unclear, and further studies will be needed. …”
Publicado 2020
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45493por Sun, Hui-Chuan, Zhu, Xiao-Dong, Zhou, Jian, Gao, Qiang, Shi, Ying-Hong, Ding, Zhen-Bing, Huang, Cheng, Qiu, Shuang-Jian, Ren, Ning, Shi, Guo-Ming, Sun, Jian, Ye, Qing-Hai, Huang, Xiao-Wu, Yang, Xin-Rong, Fan, Jia“…According to the Liver Cancer Study Group of Japan classification of PVTT, there were 7, 11, and 12 participants with Vp1, Vp2, and Vp3, respectively. …”
Publicado 2020
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45494por Kaneko, Hidehiro, Itoh, Hidetaka, Kiriyama, Hiroyuki, Kamon, Tatsuya, Fujiu, Katsuhito, Morita, Kojiro, Michihata, Nobuaki, Jo, Taisuke, Takeda, Norifumi, Morita, Hiroyuki, Yasunaga, Hideo, Komuro, Issei“…Medical records of 1,980,476 individuals with neither prior history of CVD nor sleep disorders were extracted from the Japan Medical Data Center. Restfulness from sleep was subjectively assessed using information from the questionnaires at initial health check-ups. …”
Publicado 2020
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45495por Zhao, Weijie“…[Image: see text] George Church Professor of Genetics at Harvard Medical School and Professor of Health Sciences and Technology at Harvard and MIT, USA [Image: see text] Paul Freemont Professor of Structural Biology in the Department of Infectious Disease at Imperial College and a member of the Science Advisory Board of Tierra Biosciences, UK [Image: see text] Akihiko Kondo Professor in School of Science, Technology and Innovation, and Department of Chemical Science and Engineering at Kobe University, Japan [Image: see text] Christina Smolke Professor of Bioengineering and of Chemical Engineering at Stanford University and CEO of Antheia Inc., USA [Image: see text] Xian-En Zhang Professor at the Institute of Biophysics, Chinese Academy of Sciences, China [Image: see text] Chenli Liu (Chair) Professor and Director of Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, China [Image: see text] Jim Collins Termeer Professor of Medical Engineering & Science and Professor of Biological Engineering at MIT, USA [Image: see text] Jay Keasling Professor of Chemical Engineering and Bioengineering at the University of California, Berkeley, USA [Image: see text] Sang Yup Lee Dean of KAIST Institutes and Distinguished Professor in the Department of Chemical and Biomolecular Engineering at Korea Advanced Institute of Science and Technology (KAIST), South Korea [Image: see text] Claudia Vickers Director of the Future Science Platform in Synthetic Biology at Commonwealth Science and Industry Research Organization (CSIRO), Australia [Image: see text] Guoping Zhao Professor at the Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, China…”
Publicado 2020
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45496“…INTRODUCTION: There is a need for evidence-based measures to examine the risk factors for lifestyle-related diseases. In Japan, a 2-hour interval between dinner and sleep is recommended as a healthy practice. …”
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45497por Kakiuchi, Toshihiko, Hashiguchi, Kazutoshi, Imamura, Ichiro, Nakayama, Aiko, Takamori, Ayako, Okuda, Masumi, Matsuo, Muneaki“…BACKGROUND: The resistance rate of Helicobacter pylori to clarithromycin (CAM) is high among infected children in Japan. Therefore, a new method for detecting CAM-resistant H. pylori using a minimally invasive technique is strongly desired. …”
Publicado 2020
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45498“…Esaxerenone is a novel selective mineralocorticoid receptor (MR) blocker that was recently approved in Japan to treat hypertension. In phase II and III studies, esaxerenone plus a renin–angiotensin system inhibitor markedly reduced the urinary albumin-to-creatinine ratio (UACR) in hypertensive patients with diabetic nephropathy. …”
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45499por Tokumitsu, Keita, Yasui-Furukori, Norio, Adachi, Naoto, Kubota, Yukihisa, Watanabe, Yoichiro, Miki, Kazuhira, Azekawa, Takaharu, Edagawa, Koji, Katsumoto, Eiichi, Hongo, Seiji, Goto, Eiichiro, Ueda, Hitoshi, Kato, Masaki, Yoshimura, Reiji, Nakagawa, Atsuo, Kikuchi, Toshiaki, Tsuboi, Takashi, Shimoda, Kazutaka, Watanabe, Koichiro“…CONCLUSIONS: Approximately 40% of patients in Japan with a diagnosis of bipolar disorder have received antidepressants. …”
Publicado 2020
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45500por Wang, Yeming, Zhong, Wu, Salam, Alex, Tarning, Joel, Zhan, Qingyuan, Huang, Jian-an, Weng, Heng, Bai, Changqing, Ren, Yanhong, Yamada, Koichi, Wang, Dayan, Guo, Qiang, Fang, Qiongqiong, Tsutomu, Sakurai, Zou, Xiaohui, Li, Haibo, Gillesen, Annelies, Castle, Lyndsey, Chen, Cheng, Li, Hongyan, Zhen, Jing, Lu, Binghuai, Duan, Jun, Guo, Liping, Jiang, Jinfang, Cao, Ruiyuan, Fan, Guohui, Li, Jintong, Hayden, Frederick G., Wang, Chen, Horby, Peter, Cao, Bin“…Participants received one of two dosing regimens; Japan licensed dose (1600 mg BID on day 1 and 600 mg BID on the following days) and the higher dose (1800 mg/800 mg BID) trialed in uncomplicated influenza. …”
Publicado 2020
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