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  1. 45881
    “…This cross-sectional study in Japan included 1836 older adults in the 70- and 80-year-old groups. …”
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    The Association Between Longevity-Associated FOXO3 Allele and Heart Disease in Septuagenarians and Octogenarians: The SONIC Study
  2. 45882
    “…At this time, the virus was found to have spread to South Korea, Japan, and other countries. A high case fatality rate is reported for SFTS, ranging from 12–50% within various sources. …”
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    Serum proteomics of severe fever with thrombocytopenia syndrome patients
  3. 45883
    “…SETTING: A prospective, multicentre observational registry of collaborating hospitals in Osaka, Japan. PARTICIPANTS: We enrolled 659 patients with HFpEF hospitalised for acute decompensated heart failure (men/women: 296/363). …”
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    Time-sensitive prognostic performance of an afterload-integrated diastolic index in heart failure with preserved ejection fraction: a prospective multicentre observational study
  4. 45884
    “…We aimed to investigate the association of ERBB2 amplification and gene coalterations with response and resistance to trastuzumab-combined chemotherapy. METHODS: The SCRUM-Japan GI-SCREEN was a comprehensive genomic profiling project of GI cancer tissues using Oncomine Cancer Research Panel and Oncomine Comprehensive Assay. …”
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    Association of ERBB2 Copy Number and Gene Coalterations With Trastuzumab Efficacy and Resistance in Human Epidermal Growth Factor Receptor 2–Positive Esophagogastric and Gastric Cancer
  5. 45885
    “…CONCLUSION: Internet use was associated with sufficient physical activity, and this association may differ depending on the social isolation among community-dwelling older adults in Japan.…”
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    Internet use and physical activity of older adults during the COVID-19 pandemic: a cross-sectional study in a northern Japanese City
  6. 45886
    “…METHODS: Images captured on a desktop fundus camera (Topcon TRC-50DX, Japan) for a previous study with 135 consecutive patients (233 eyes) with established diabetes mellitus, with or without DR were analysed by the AI algorithm. …”
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    Towards a Device Agnostic AI for Diabetic Retinopathy Screening: An External Validation Study
  7. 45887
    “…METHODS: Survey participants were caregivers working at 284 nursing homes in Ibaraki prefecture, Japan. The survey period was from September 2020 to March 2021. …”
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    Mental Health of Caregivers Working in Nursing Homes during the COVID-19 Pandemic
  8. 45888
    “…METHODS: This retrospective, longitudinal cohort study included 82 001 participants who visited a primary care centre in Japan. Participants were categorized into CKD risk groups and sleep duration categories according to their self-reported average nightly sleep duration. …”
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    Longitudinal relationship between long sleep duration and future kidney function decline
  9. 45889
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    Establishing a robotic-assisted PCI program: experiences at a large tertiary referral center
  10. 45890
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    Selection of an impedance- or magnetic field-based electro-anatomical mapping platform does not affect outcomes of outflow tract premature ventricular complex manual ablation
  11. 45891
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    Gender difference in heart failure with preserved ejection fraction: clinical profiles, examinations, and prognosis
  12. 45892
    “…OBJECTIVE: We aimed to examine the effectiveness of a digital self-monitoring device on glucose levels and activity of workers with diabetes in Japan. The primary outcomes were changes in blood glucose levels, and the secondary outcomes were changes in weight and BMI. …”
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    Effects of Feedback From Self-Monitoring Devices on Lifestyle Changes in Workers with Diabetes: 3-Month Randomized Controlled Pilot Trial
  13. 45893
    “…CLINICAL TRIAL REGISTRY: Japan Registry of Clinical Trials registration number: jRCTs031190092 SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s12325-022-02243-w.…”
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    Effects of Elobixibat in Patients with Diabetes and Concomitant Chronic Constipation: an 8-week, Prospective, Single-center, Single-arm Study
  14. 45894
    “…This study aimed to identify the types of cognitive biases experienced by physicians in emergency rooms in Japan. METHODS: We conducted a questionnaire survey using Nikkei Medical Online (Internet) from January 21 to January 31, 2019. …”
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    Cognitive biases encountered by physicians in the emergency room
  15. 45895
    “…METHODS: We investigated wrong-patient medication errors in incident reports voluntarily reported by medical staff using a web-based incident reporting system from 2015 to 2016 at a university hospital in Japan. Incident report content was separately evaluated by four evaluators using investigational methods for clinical incidents from the Clinical Risk Unit and the Association of Litigation and Risk Management. …”
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    Describing and Quantifying Wrong-Patient Medication Errors Through a Study of Incident Reports
  16. 45896
    “…PATIENTS AND METHODS: We conducted a retrospective cohort study of women who visited the general internal medicine outpatient department of a university hospital in Japan between 2016 and 2022. Women who were prescribed iron supplements were included in the study. …”
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    The Clinical and Biological Manifestations in Women with Iron Deficiency Without Anemia Compared to Iron Deficiency Anemia in a General Internal Medicine Setting: A Retrospective Cohort Study
  17. 45897
    “…METHOD: The CLOT-COVID study was a retrospective multicenter cohort study enrolling 2894 consecutive hospitalized patients with COVID-19 between April 2021 and September 2021 among 16 centers in Japan. The present study consisted of 2690 patients aged over 18 years with available body mass index (BMI), who were divided into an obesity group (BMI ≥30) (N = 457) and a non-obesity group (BMI <30) (N = 2233). …”
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    Influence of obesity on incidence of thrombosis and disease severity in patients with COVID-19: From the CLOT-COVID study
  18. 45898
    “…BACKGROUND: Imeglimin is a first-in-class novel oral antidiabetic marketed in Japan as TWYMEEG(®) to treat type 2 diabetes mellitus. …”
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    Pharmacokinetics of Imeglimin in Caucasian and Japanese Healthy Subjects
  19. 45899
    “…METHODS: This study is a subanalysis of an historical registry study from 71 centers in Japan. We included patients taking vitamin K antagonists for NVAF and excluded those with mechanical heart valves or a history of pulmonary thrombosis or deep vein thrombosis. …”
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    Association between Acid-Suppressive Drugs and Clinical Outcomes in Patients with Nonvalvular Atrial Fibrillation
  20. 45900
    “…Edaravone (Radicava(®)) (Mitsubishi Tanabe Pharma Corporation, Tokyo, Japan), approved in the United States (US) for ALS in adults in 2017, was shown in a clinical trial to slow the rate of physical functional decline in ALS and is administered intravenously. …”
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    Analysis of the US Safety Data for Edaravone (Radicava(®)) From the Third Year After Launch
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