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45921por Nakamura, Yuzuki, Kubota, Jo, Nishimura, Yukiko, Nagata, Kento, Nishimura, Mayumi, Daino, Kazuhiro, Ishikawa, Atsuko, Kaneko, Takehito, Mashimo, Tomoji, Kokubo, Toshiaki, Takabatake, Masaru, Inoue, Kazumasa, Fukushi, Masahiro, Arai, Masami, Saito, Mitsue, Shimada, Yoshiya, Kakinuma, Shizuko, Imaoka, Tatsuhiko“…Herein, we report the creation and characterization of a novel Brca1 mutant rat model harboring the germline L63X mutation, which mimics a founder mutation in Japan, through CRISPR‐Cas9–based genome editing. …”
Publicado 2022
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45922por Yonemori, Kan, Yunokawa, Mayu, Ushijima, Kimio, Sakata, Jun, Shikama, Ayumi, Minobe, Shinichiro, Usami, Tomoka, Enomoto, Takayuki, Takehara, Kazuhiro, Hasegawa, Kosei, Yamagami, Wataru, Yamamoto, Keiko, Han, Shirong, Dutta, Lea, Orlowski, Robert, Miura, Takuma, Makker, Vicky, Fujiwara, Keiichi“…One hundred four patients were randomized in Japan (data cutoff, October 26, 2020; median follow‐up, 11.8 [range, 1.1–26.9] months). …”
Publicado 2022
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45923por Takahashi, Yuki, Maki, Ryunosuke, Tsuruta, Kodai, Tada, Makoto, Arai, Wataru, Shindo, Yuma, Nakamura, Yasuyuki, Miyajima, Masahiro, Watanabe, Atsushi“…BACKGROUND: Soft coagulation using the VIO soft coagulation system is used to treat minor lung air leaks during pulmonary resection in Japan. We previously reported that it has a similar effect as the air leak treatment with fibrin glue. …”
Publicado 2022
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45924por Morita, Masaya, Ando, Shuntaro, Kiyono, Tomoki, Morishima, Ryo, Yagi, Tomoko, Kanata, Sho, Fujikawa, Shinya, Yamasaki, Syudo, Nishida, Atsushi, Kasai, Kiyoto“…This longitudinal cohort study used data from the Tokyo Teen Cohort study in Tokyo, Japan, for two years between October 2012 and January 2015. …”
Publicado 2021
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45925“…Moreover, in both the prepandemic and postpandemic years, the FTITAs to North America, Japan/South Korea, Europe, and Southeast Asia are significantly higher than those to Oceania, Middle East, South America, and Africa. …”
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45926por Ito, Miyuki, Maeda, Daichi, Matsue, Yuya, Shiraishi, Yasuyuki, Dotare, Taishi, Sunayama, Tsutomu, Nogi, Kazutaka, Takei, Makoto, Ueda, Tomoya, Nogi, Maki, Ishihara, Satomi, Nakada, Yasuki, Kawakami, Rika, Kagiyama, Nobuyuki, Kitai, Takeshi, Oishi, Shogo, Akiyama, Eiichi, Suzuki, Satoshi, Yamamoto, Masayoshi, Kida, Keisuke, Okumura, Takahiro, Nagatomo, Yuji, Kohno, Takashi, Nakano, Shintaro, Kohsaka, Shun, Yoshikawa, Tsutomu, Saito, Yoshihiko, Minamino, Tohru“…We retrospectively analyzed a combined dataset from three large-scale registries of hospitalized patients with HF in Japan (NARA-HF, WET-HF, and REALITY-AHF) and patients diagnosed with HF with reduced or mildly reduced left ventricular ejection fraction (HFr/mrEF) before admission. …”
Publicado 2022
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45927por Katsuno, Yuta, Ueki, Yoshino, Ito, Keiichi, Murakami, Satona, Aoyama, Kiminori, Oishi, Naoya, Kan, Hirohito, Matsukawa, Noriyuki, Nagao, Katashi, Tatsumi, Hiroshi“…Patients with post-stroke aphasia in Japan are increasing due to population aging and the advancement of medical treatment. …”
Publicado 2022
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45928por Lashkarbolouk, Narges, Mazandarani, Mahdi, Pourghazi, Farzad, Eslami, Maysa, Khonsari, Nami Mohammadian, Ghonbalani, Zahra Nouri, Ejtahed, Hanieh-Sadat, Qorbani, Mostafa“…For example, all the studies done in Japan showed an increase in the consumption of snacks and sweets, leading to weight gain in the patients. …”
Publicado 2022
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45929por Iwatate, Mineo, Hirata, Daizen, Francisco, Carlos Paolo D., Co, Jonard Tan, Byeon, Jeong‐Sik, Joshi, Neeraj, Banerjee, Rupa, Quach, Duc Trong, Aye, Than Than, Chiu, Han‐Mo, Lau, Louis H. S., Ng, Siew C., Ang, Tiing Leong, Khomvilai, Supakij, Li, Xiao‐Bo, Ho, Shiaw‐Hooi, Sano, Wataru, Hattori, Santa, Fujita, Mikio, Murakami, Yoshitaka, Shimatani, Masaaki, Kodama, Yuzo, Sano, YasushiEnlace del recurso
Publicado 2022
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45930por Fukushima, Hidetada, Nishioka, Yuichi, Kasahara, Kei, Asai, Hideki, Sonobe, Shota, Imamura, Tomoaki, Muro, Shigeo, Nishio, Kenji“…We conducted this population-based retrospective study in Nara Prefecture, Japan. The Nara Prefectural Government implemented a screening protocol for COVID-19 comprising the following symptom criteria (fever, cough, sore throat, headache, malaise, dysgeusia, or anosmia) and epidemiological criteria (contact history with confirmed COVID-19 cases or people with upper respiratory symptoms, or travel to areas with high infection rate). …”
Publicado 2022
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45931por Kissel, Theresa, Hafkenscheid, Lise, Wesemael, Tineke J., Tamai, Mami, Kawashiri, Shin‐ya, Kawakami, Atsushi, El‐Gabalawy, Hani S., van Schaardenburg, Dirkjan, Rantapää‐Dahlqvist, Solbritt, Wuhrer, Manfred, van der Helm‐van Mil, Annette H. M., Allaart, Cornelia F., van der Woude, Diane, Scherer, Hans U., Toes, Rene E. M., Huizinga, Tom W. J.“…METHODS: Using liquid chromatography, we analyzed IgG ACPA VDG profiles in 7 different cohorts from Japan, Canada, The Netherlands, and Sweden. We assessed 106 healthy individuals, 228 individuals with presymptomatic RA, 277 individuals with arthralgia, 307 patients with new‐onset/early RA, and 117 RA patients after prespecified treatment regimens. …”
Publicado 2022
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45932por Uhara, Hisashi, Tsuchida, Tetsuya, Kiyohara, Yoshio, Akamatsu, Ayumi, Sakamoto, Takahiko, Yamazaki, Naoya“…Nivolumab, a monoclonal antibody against human programmed death 1, was approved for the treatment of melanoma in July 2014 in Japan. Because the Japanese phase II studies (ONO‐4538‐02, ONO‐4538‐08) enrolled small numbers of melanoma patients, post‐marketing surveillance (PMS; JapicCTI‐163 272) was conducted to collect safety data in a larger patient population. …”
Publicado 2022
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45933por Nakao, Masahiro, Nanba, Yukiko, Okumura, Asumi, Hasegawa, Junichi, Toyokawa, Satoshi, Ichizuka, Kiyotake, Kanayama, Naohiro, Satoh, Shoji, Tamiya, Nanako, Nakai, Akihito, Fujimori, Keiya, Maeda, Tsugio, Suzuki, Hideaki, Iwashita, Mitsutoshi, Oka, Akira, Ikeda, Tomoaki“…SETTING: Database of the Recurrence Prevention Committee, Japan Obstetric Compensation System for Cerebral Palsy. …”
Publicado 2022
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45934por Pantaleón Sánchez, Miguel, Gimeno Garcia, Antonio‐Z, Bernad Cabredo, Belen, García‐Rodríguez, Ana, Frago, Santiago, Nogales, Oscar, Diez Redondo, Pilar, Puig, Ignasi, Romero Mascarell, Cristina, Romero Sánchez‐Miguel, Ivan, Caballero, Noemí, Ibañez, Ines, Hernandez Negrín, Domingo, Bujedo Sadornill, Gema, Pérez Oltra, Alicia, Pérez Berbegal, Rocio, Casals, Gemma, Seoane Urgorri, Agustín, Riu Pons, Faust, Amorós, Jaume, Alvarez‐Gonzalez, Marco AntonioEnlace del recurso
Publicado 2022
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45935por Aoki, Rei, Saito, Takeo, Ninomiya, Kohei, Shimasaki, Ayu, Ashizawa, Takuma, Ito, Kenta, Ikeda, Masashi, Iwata, Nakao“…Nonpsychiatric data (20 binary traits [mainly nonpsychiatric complex disorders] and 34 quantitative traits [mainly laboratory examinations and physical characteristics]) were obtained from Biobank Japan and UK Biobank for EAS and EUR samples, respectively. …”
Publicado 2022
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45936por Takahashi, Miwako, Akamatsu, Go, Iwao, Yuma, Tashima, Hideaki, Yoshida, Eiji, Yamaya, Taiga“…CONCLUSIONS: This was the first time that the raphe nuclei, anterior nuclei, and dorsomedial nuclei were successfully visualised using the first hemispherical brain PET. TRIAL REGISTRATION : Japan Registry of Clinical Trials, jRCTs032210086, Registered 13 May 2021, https://jrct.niph.go.jp/latest-detail/jRCTs032210086.…”
Publicado 2022
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45937por Seto, Hiroe, Oyama, Asuka, Kitora, Shuji, Toki, Hiroshi, Yamamoto, Ryohei, Kotoku, Jun’ichi, Haga, Akihiro, Shinzawa, Maki, Yamakawa, Miyae, Fukui, Sakiko, Moriyama, Toshiki“…To this end, we compared the reliability of gradient boosting decision tree (GBDT) and logistic regression (LR) models using data obtained from the Kokuho-database of the Osaka prefecture, Japan. To develop the models, we focused on 16 predictors from health checkup data from April 2013 to December 2014. …”
Publicado 2022
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45938por Takahashi, Masaki, Wada, Takeshi, Nakae, Ryuta, Fujiki, Yu, Kanaya, Takahiro, Takayama, Yasuhiro, Suzuki, Go, Naoe, Yasutaka, Yokobori, Shoji“…This study aimed to investigate the relationship between AT activity levels and long-term outcomes in patients with TBI; this was a sub-analysis of a prior study that collected blood samples of trauma patients prospectively in a tertiary care center in Kawaguchi City, Japan. We included patients with isolated TBI (iTBI) aged ≥16 years admitted directly to our hospital within 1 h after injury between April 2018 and March 2021. …”
Publicado 2022
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45939por Kido, Ai, Miyake, Masahiro, Tamura, Hiroshi, Hiragi, Shusuke, Kimura, Takeshi, Yoshida, Satomi, Takeuchi, Masato, Ohtera, Shosuke, Takahashi, Ayako, Ooto, Sotaro, Kawakami, Koji, Kuroda, Tomohiro, Tsujikawa, Akitaka“…DESIGN: A population-based cohort study conducted using the National Database of Health Insurance Claims and Specific Health Checkups of Japan (NDB), a national claims database managed by the Japanese Ministry of Health, Labour, and Welfare (MHLW). …”
Publicado 2022
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45940por Kanno, Atsuhiro, Kimura, Ryo, Ooyama, Chika, Ueda, Juri, Miyazawa, Isabelle, Fujikawa, Yuko, Sato, Shigeru, Koinuma, Nobuo, Ohara, Takahiro, Sumitomo, Kazuhiro, Furukawa, Katsutoshi“…OBJECTIVE: Pneumonia is a disease with high morbidity and mortality among older individuals in Japan. In practice, most older patients with pneumonia are not required ventilatory management and are not necessarily in critical respiratory condition. …”
Publicado 2022
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