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46181“…Furthermore, we revealed a threefold independent allopolyploid origin of this hybrid species in Japan, China, and Kamchatka. CONCLUSIONS: Unglaciated parts of the Eastern Austrian Alps and arctic Eurasia, including Beringia, served as major glacial refugia of the Eurasian A. lyrata lineage, whereas A. halleri and its various subspecies probably survived in refuges in Central Europe and Eastern Asia with a large distribution gap in between. …”
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46182por Nagai, Hideaki, Ikematsu, Hideyuki, Tenjinbaru, Kazuyoshi, Maeda, Atsushi, Dramé, Mamadou, Roman, François P“…METHODS: This open-label, single-group study was conducted at two centres in Japan in healthy Japanese males and females aged 20-64 years (n = 100). …”
Publicado 2010
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46183por Takahashi, Ryoji, Dubouzet, Joseph G, Matsumura, Hisakazu, Yasuda, Kentaro, Iwashina, Tsukasa“…RESULTS: B09121, an accession with light purple flowers, was discovered in southern Japan. Genetic analysis revealed that the gene responsible for the light purple flowers was allelic to the W1 locus encoding flavonoid 3'5'-hydroxylase (F3'5'H). …”
Publicado 2010
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46184por Watanabe, Naoto, Satoh, Youichi, Fujita, Tatsuo, Ohta, Takeshi, Kose, Hiroyuki, Muramatsu, Youji, Yamamoto, Takuji, Yamada, Takahisa“…BACKGROUND: Marbling defined by the amount and distribution of intramuscular fat, so-called Shimofuri, is an economically important trait of beef cattle in Japan. Our previous study detected 3 single nucleotide polymorphisms (SNPs), g.231054C > T, g.3109537C > T and c.*188G > A, respectively, in the 5' flanking region of the titin (TTN), the 5' flanking region of the ribosomal protein L27a (RPL27A) and the 3' untranslated region of the akirin 2 genes (AKIRIN2), which have been considered as positional functional candidates for the genes responsible for marbling, and showed association of these SNPs with marbling in Japanese Black beef cattle. …”
Publicado 2011
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46185por Fujii, Hitoshi, Matsuyama, Akifumi, Komoda, Hiroshi, Sasai, Masao, Suzuki, Minoru, Asano, Tomoyuki, Doki, Yuichiro, Kirihata, Mitsunori, Ono, Koji, Tabata, Yasuhiko, Kaneda, Yasufumi, Sawa, Yoshiki, Lee, Chun Man“…Hemagglutinating Virus of Japan Envelope (HVJ-E) is used as a vehicle for gene delivery because of its high ability to fuse with cells. …”
Publicado 2011
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46186“…Three species occur in China: Selenops bursarius Karsch 1879, also known from Japan, Korea and Taiwan, Selenops ollarius Zhu, Sha, & Chen 1990, and Selenops radiatus Latreille 1819, the type of the genus and most widespread selenopid. …”
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46187“…Body mass index (BMI), percentages of body fat (PBFs), basal metabolic rate (BMR), and intra-abdominal visceral fat (IVF) were measured using an Omron body fat analyzer (Omron Corporation, Tokyo, Japan). Fat mass (FM), fat free mass (FFM), waist–hip ratio (WHR), and sum of four skinfolds (SF4) were also taken into consideration. …”
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46188por Boffetta, Paolo, McLerran, Dale, Chen, Yu, Inoue, Manami, Sinha, Rashmi, He, Jiang, Gupta, Prakash Chandra, Tsugane, Shoichiro, Irie, Fujiko, Tamakoshi, Akiko, Gao, Yu-Tang, Shu, Xiao-Ou, Wang, Renwei, Tsuji, Ichiro, Kuriyama, Shinichi, Matsuo, Keitaro, Satoh, Hiroshi, Chen, Chien-Jen, Yuan, Jian-Min, Yoo, Keun-Young, Ahsan, Habibul, Pan, Wen-Harn, Gu, Dongfeng, Pednekar, Mangesh Suryakant, Sasazuki, Shizuka, Sairenchi, Toshimi, Yang, Gong, Xiang, Yong-Bing, Nagai, Masato, Tanaka, Hideo, Nishino, Yoshikazu, You, San-Lin, Koh, Woon-Puay, Park, Sue K., Shen, Chen-Yang, Thornquist, Mark, Kang, Daehee, Rolland, Betsy, Feng, Ziding, Zheng, Wei, Potter, John D.“…METHODS AND FINDINGS: A pooled cross-sectional analysis was conducted to evaluate the association between baseline body mass index (BMI, measured as weight in kg divided by the square of height in m) and self-reported diabetes status in over 900,000 individuals recruited in 18 cohorts from Bangladesh, China, India, Japan, Korea, Singapore and Taiwan. Logistic regression models were fitted to calculate cohort-specific odds ratios (OR) of diabetes for categories of increasing BMI, after adjustment for potential confounding factors. …”
Publicado 2011
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46189“…Currently there are two NAI drugs which are licensed worldwide: oseltamivir (Tamiflu(®)) and zanamivir (Relenza(®)); and two drugs which have received recent approval in Japan: peramivir and laninamivir. Until recently, the prevalence of antiviral resistance has been relatively low. …”
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46190por Sakata, Satoko, Yoshihara, Tatsuya, Arima, Hisatomi, Shiraishi, Fumie, Oniki, Hideyuki, Takahashi-Yanaga, Fumi, Matsumura, Kiyoshi, Sasaguri, Toshiyuki“…DESIGN: A randomised, open-label, crossover trial with 117 healthy Japanese (20–39 years) whose genotypes were determined (*1/*1, n=47; *1/*2, n=48; *2/*2, n=22) was performed at Kyushu University Hospital, Fukuoka, Japan. Participants were randomly assigned to treatment: sublingual spray of GTN (0.3 mg) or ISDN (1.25 mg). …”
Publicado 2011
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46191por Sato, Ryosuke, Watanabe, Hiroshi, Shirai, Kenji, Ohki, Shigeru, Genma, Rieko, Morita, Hiroshi, Inoue, Eisuke, Takeuchi, Masahiro, Maekawa, Masato, Nakamura, Hirotoshi“…SETTING: A general hospital in Hamamatsu, Japan. PARTICIPANTS: 111 young adults (42 men and 69 women; aged 19–30 years) born with VLBW between 1980 and 1990. …”
Publicado 2012
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46192“…METHODS: One hundred and five elderly predialysis CKD patients who had never been treated for osteoporosis and had never used calcium supplements, vitamin D supplements, or phosphate binders were enrolled in this cross-sectional study in Tokyo, Japan. We investigated the prevalence of vertebral fracture and measured serum calcium, phosphate, 1,25(OH)(2) vitamin D [1,25(OH)(2)D], intact PTH, FGF23, alkaline phosphatase, and urinary N-terminal telopeptide levels. …”
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46193por Adachi, Misa, Yamaoka, Kazue, Watanabe, Mariko, Nishikawa, Masako, Kobayashi, Itsuro, Hida, Eisuke, Tango, Toshiro“…Twenty general practitioners in 20 clinics in Kanagawa prefecture, Japan, were involved. 193 adults (51% men, mean age 61.3 years) with type 2 diabetes and HbA(1c) ≥6.5% who received treatment in medical clinics were the participants. …”
Publicado 2013
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46194por Kubota, Hiroshi, Miyata, Hiroaki, Motomura, Noboru, Ono, Minoru, Takamoto, Shinichi, Harii, Kiyonori, Oura, Norihiko, Hirabayashi, Shinichi, Kyo, Shunei“…METHODS: We reviewed 73,700 cases registered in the Japan Adult Cardiovascular Surgery Database (JACVSD) during the period from 2004 to 2009 and divided them into five groups: 26,597 of isolated coronary artery bypass graft (CABG) cases, 23,136 valvular surgery cases, 17,441 thoracic aortic surgery cases, 4,726 valvular surgery plus CABG cases, and 1,800 thoracic aortic surgery plus CABG cases. …”
Publicado 2013
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46195por Iwakiri, Takashi, Fujimoto, Shouichi, Kitagawa, Kiyoki, Furuichi, Kengo, Yamahana, Junya, Matsuura, Yunosuke, Yamashita, Atsushi, Uezono, Shigehiro, Shimao, Yoshiya, Hisanaga, Shuichi, Tokura, Takeshi, Wada, Takashi, Kitamura, Kazuo, Asada, Yujiro“…METHODS: We enrolled 122 patients with ANCA-associated glomerulonephritis diagnosed at several institutions in Japan between January 2000 and March 2010. Twenty patients were excluded because of observation durations of <1 year, and/or because their biopsy specimens contained <10 glomeruli. …”
Publicado 2013
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46196por Ma, Wen-Jie, Hashii, Minako, Munesue, Toshio, Hayashi, Kenshi, Yagi, Kunimasa, Yamagishi, Masakazu, Higashida, Haruhiro, Yokoyama, Shigeru“…METHODS: Variations in the OXTR gene were analyzed in 132 ASD patients at Kanazawa University Hospital in Japan and 248 unrelated healthy Japanese volunteers by re-sequencing and real-time polymerase chain reaction-based genotyping. …”
Publicado 2013
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46197por Chaudhry, M. Ahmad, Omaruddin, Romaica A., Brumbaugh, Christopher D., Tariq, Muhammad A., Pourmand, NaderEnlace del recurso
Publicado 2013
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46198por Atsukawa, Masanori, Tsubota, Akihito, Shimada, Noritomo, Kondo, Chisa, Itokawa, Norio, Nakagawa, Ai, Hashimoto, Satomi, Fukuda, Takeshi, Matsushita, Yoko, Kidokoro, Hideko, Narahara, Yoshiyuki, Nakatsuka, Katsuhisa, Iwakiri, Katsuhiko, Kawamoto, Chiaki, Sakamoto, Choitsu“…Patients with chronic hepatitis C (CHC) in Japan are older on average than those in Western countries. …”
Publicado 2013
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46199por Hosoya, Tatsuo, Kimura, Kenjiro, Itoh, Sadayoshi, Inaba, Masaaki, Uchida, Shunya, Tomino, Yasuhiko, Makino, Hirofumi, Matsuo, Seiichi, Yamamoto, Tetsuya, Ohno, Iwao, Shibagaki, Yugo, Iimuro, Satoshi, Imai, Naohiko, Kuwabara, Masanari, Hayakawa, Hiroshi“…The present study will enroll, at 64 medical institutions in Japan, 400 Japanese patients aged 20 years or older who have hyperuricemia without gouty arthritis, who present CKD stage 3, and whose SUA concentration is 7.1-10.0 mg/dL. …”
Publicado 2014
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