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  1. 46361
    “…Children with FRNS/SDNS are usually treated with immunosuppressive agents such as cyclosporine, cyclophosphamide, or mizoribine in Japan. However, 10–20% of children receiving immunosuppressive agents still show frequent relapse and/or steroid dependence during or after treatment, which is defined as complicated FRNS/SDNS. …”
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    Study protocol: mycophenolate mofetil as maintenance therapy after rituximab treatment for childhood-onset, complicated, frequently-relapsing nephrotic syndrome or steroid-dependent nephrotic syndrome: a multicenter double-blind, randomized, placebo-controlled trial (JSKDC07)
  2. 46362
    “…METHODS: An anonymous self-administered questionnaire survey was conducted in October 2015 in 988 households in areas affected by the Great East Japan Earthquake and Tsunami. The data collected on sociodemographic and socioenvironmental characteristics included the presence of pre-disaster acquaintances in the neighborhood and social support for child-rearing. …”
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    Factors associated with social support in child-rearing among mothers in post-disaster communities
  3. 46363
    “…All patients were evaluated for with or without sarcopenia based on the sarcopenia diagnostic criteria of the Japan Society of Hepatology. Then, patient’s characteristics and laboratory parameters were divided into two groups with or without sarcopenia and compared. …”
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    Relationship Between Sarcopenia and Both Physical Activity and Lifestyle in Patients With Chronic Liver Disease
  4. 46364
    “…METHODS: Male HIV patients who visited the outpatient clinic of Teikyo University Hospital, Tokyo, Japan in 2015 and had been treated with anti-retroviral therapy for more than six months were enrolled. …”
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    2255. Fibroblast Growth Factor 23, a Potential Risk Factor for Cardiovascular Diseases Is Associated with Abacavir/Lamivudine Use in HIV Patients
  5. 46365
    “…BACKGROUND: In 2010, a multispecies outbreak of IMP type carbapenemase-producing Enterobacteriaceae (IMP-CPE) occurred at a large acute care hospital in Japan. The outbreak continued for years involving more than 100 patients mainly in surgical wards. …”
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    1201. A Prolonged Multispecies Outbreak of Carbapenemase-Producing Enterobacteriaceae Due to Transmissible Plasmid With Carbapenemase Gene
  6. 46366
    “…METHODS: The search strategy consists of three Methods. academic literature review, Google search, and questionnaire to the Embassies of Japan in target countries. The target countries were 59 high and 79 upper-middle income countries defined by country income classification for the World Bank. …”
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    2184. Surveillance System of Healthcare-Associated Infection in High and Upper-Middle Income Countries: A Scoping Review
  7. 46367
    “…RESULTS: Seven studies conducted in children in the United States, Japan, Finland, Germany, thr UK, and Canada were identified including four TNCC studies, one cohort study and one RCT (Figure 1). …”
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    1973. A Meta-Analysis of the Effectiveness of LAIV4 and IIV against Influenza A/H3N2 Strains in Children 2–18 Years of Age During the 2016–2017 Season
  8. 46368
    “…METHODS: We analyzed 1,406 cases tested by indirect immunoperoxidase assay (IP) using seven rickettsial antigens—one R. japonica and six O. tsutsugamushi serotypes (Kato, Karp, Gilliam, Irie/Kawasaki, Hirano/Kuroki, and Shimokoshi)—between 2003 and 2016 at two reference centers in Japan. Patient sera were 2-fold diluted from 1:40 to 1:40,960, and the titer was expressed as the reciprocal values. …”
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    435. Serological Cross-Reactivity Between Rickettsia japonica and Orientia tsutsugamushi, and Among Orientia tsutsugamushi Serotypes
  9. 46369
    “…METHODS: Subjects were PeV-A3-infected infants less than 4 months in Niigata, Japan during 2013–2014, and follow-up serum samples were obtained longitudinally from the patients at 3, 6 months, 1 and 3 years after the infection. …”
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    2349. Long-Term Neurological Outcome and Neutralizing Antibody Titers Against Paraechovirus-A3 (PeV-A3) in Children who Developed PeV-A3-Related Diseases in Neonatal and Infantile Periods
  10. 46370
    “…Improvement in oral intake was defined as no TPN for more than 7 days, and improvement in ascites was defined as a decrease in ascites of more than one grade defined by the Japan Clinical Oncology Study Group trial (JCOG0106). …”
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    Modified FOLFOX6 as a first-line treatment for patients with advanced gastric cancer with massive ascites or inadequate oral intake
  11. 46371
    “…SETTINGS: Community-based medical checkups, called specific health checkups started in Japan since 2008. This checkup includes standard medical examinations as well as a specific questionnaire related to lifestyle habits. …”
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    Associations between questionnaires on lifestyle and atherosclerotic cardiovascular disease in a Japanese general population: A cross-sectional study
  12. 46372
    por André, Marcos Rogério
    Publicado 2018
    “…While Ehrlichia sp. closely related to E. canis has been reported in wild felids from Brazil and Japan, Anaplasma sp. closely related to A. phagocytophilum has been detected in wild felids from Brazil and Africa. …”
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    Diversity of Anaplasma and Ehrlichia/Neoehrlichia Agents in Terrestrial Wild Carnivores Worldwide: Implications for Human and Domestic Animal Health and Wildlife Conservation
  13. 46373
    “…RESULTS: Overall, 251 patients were randomized (208 from China; 43 from Japan); 141 (56.2%) completed the 28‐week treatment period. …”
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    Adjunctive levetiracetam in the treatment of Chinese and Japanese adults with generalized tonic–clonic seizures: A double‐blind, randomized, placebo‐controlled trial
  14. 46374
    “…However, there are only few data on HIV prevalence in MSM in Japan. The objective of this study was to explore the HIV prevalence in MSM at Shinjuku 2-chome, a well known gay quarter in Tokyo. …”
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    Assessment of HIV prevalence among MSM in Tokyo using self-collected dried blood spots delivered through the postal service
  15. 46375
    “…METHODS: We conducted a two-stage genomewide association study and candidate single-nucleotide polymorphisms (SNP) association study on leisure-time exercise behavior using 13,980 discovery samples from the Japan Multi-Institutional Collaborative Cohort (J-MICC) study, and 2036 replication samples from the Hospital-based Epidemiologic Research Program at Aichi Cancer Center-2 study. …”
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    Genomewide Association Study of Leisure-Time Exercise Behavior in Japanese Adults
  16. 46376
    “…Here, we isolated a bla(IMP-6) carbapenemase-gene positive but imipenem- and meropenem-susceptible Escherichia coli (ISMS-E) strain A56-1S (imipenem and meropenem minimum inhibitory concentration, ≤ 0.125 mg/L), from a human urine specimen in Japan. A56-1S was carbapenemase negative by the Carba NP test, suggesting that IMP-6 production was low or undetectable. …”
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    The plasmid-encoded transcription factor ArdK contributes to the repression of the IMP-6 metallo-β-lactamase gene bla(IMP-6), leading to a carbapenem-susceptible phenotype in the bla(IMP-6)-positive Escherichia coli strain A56-1S
  17. 46377
    “…Level A referred to reliable sites (providing information complying with the clinical practice guidelines for various types of cancer), Level B included sites not falling under either Level A or Level C, and Level C comprised dangerous or harmful sites (providing information on treatment not approved by the regulatory authority in Japan and bombastic advertisements without any relevant clinical evidence). …”
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    Reliability of Cancer Treatment Information on the Internet: Observational Study
  18. 46378
    “…Orlistat may be useful to reduce excessive visceral fat accumulation when used in combination with diet and exercise. TRIAL REGISTRATION: Japan Pharmaceutical Information Center identifier, JapicCTI-184005. …”
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    Efficacy and Safety of Lipase Inhibitor Orlistat in Japanese with Excessive Visceral Fat Accumulation: 24-Week, Double-Blind, Randomized, Placebo-Controlled Study
  19. 46379
    “…BACKGROUND: Lychnis kiusiana Makino is an endangered perennial herb native to wetland areas in Korea and Japan. Despite its conservational and evolutionary significance, population genetic resources are lacking for this species. …”
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    Transcriptome-wide mining, characterization, and development of microsatellite markers in Lychnis kiusiana (Caryophyllaceae)
  20. 46380
    por Hisatomi, Yuko, Kugino, Kenji
    Publicado 2019
    “…Cross-sectional images of all vertebrae were obtained from radiographic computed tomography and were analyzed by using Latheta software ver. 3.0 (Hitachi-Aloka Medical, Nagasaki, Japan). The region of interest that was misrecognized in each cross-sectional image was made consistent with the anatomical structure by carrying out corrections manually and by identifying the cortical bone areas and cancellous bone areas. …”
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    Changes in bone density and bone quality caused by single fasting for 96 hours in rats
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