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46481por Yamamoto, Takamichi, Lim, Sung Chul, Ninomiya, Hirotomo, Kubota, Yuichi, Shin, Won Chul, Kim, Dong Wook, Shin, Dong Jin, Hoshida, Tohru, Iida, Koji, Ochiai, Taku, Matsunaga, Risa, Higashiyama, Hiroyuki, Hiramatsu, Hidetaka, Kim, Ji Hyun“…OBJECTIVE: Our study assessed perampanel monotherapy in patients (aged ≥12 years) with focal‐onset seizures (FOS) with or without focal to bilateral tonic‐clonic seizures (FBTCS) in Japan and South Korea. METHODS: Study 342 (NCT03201900; FREEDOM) is a single‐arm, open‐label, Phase III study. …”
Publicado 2020
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46482por Ushida, Takafumi, Kotani, Tomomi, Hayakawa, Masahiro, Hirakawa, Akihiro, Sadachi, Ryo, Nakamura, Noriyuki, Moriyama, Yoshinori, Imai, Kenji, Nakano-Kobayashi, Tomoko, Kikkawa, Fumitaka“…This population-based retrospective study was conducted based on an analysis of data collected by the Neonatal Research Network of Japan on 21,014 singleton neonates weighing ≤1,500 g between 24 and 31 weeks’ gestation during 2003–2016. …”
Publicado 2020
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46483por Berenbaum, Francis, Blanco, Francisco J, Guermazi, Ali, Miki, Kenji, Yamabe, Takaharu, Viktrup, Lars, Junor, Rod, Carey, William, Brown, Mark T, West, Christine R, Verburg, Kenneth M“…METHODS: This double-blind, randomised, phase III study enrolled adults in Europe and Japan with moderate-to-severe OA who had not responded to or could not tolerate standard-of-care analgesics. …”
Publicado 2020
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46484por Wada, Eri, Onoue, Takeshi, Kobayashi, Tomoko, Handa, Tomoko, Hayase, Ayaka, Ito, Masaaki, Furukawa, Mariko, Okuji, Takayuki, Okada, Norio, Iwama, Shintaro, Sugiyama, Mariko, Tsunekawa, Taku, Takagi, Hiroshi, Hagiwara, Daisuke, Ito, Yoshihiro, Suga, Hidetaka, Banno, Ryoichi, Kuwatsuka, Yachiyo, Ando, Masahiko, Goto, Motomitsu, Arima, Hiroshi“…RESEARCH DESIGN AND METHODS: In this 24-week, multicenter, open-label, randomized (1:1), parallel-group study, patients with non-insulin-treated type 2 diabetes at five hospitals in Japan were randomly assigned to the FGM (n=49) or SMBG (n=51) groups and were provided each device for 12 weeks. …”
Publicado 2020
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46485por Miyoshi, Yasuo, Yoshimura, Yuta, Saito, Kenichi, Muramoto, Kenzo, Sugawara, Michiko, Alexis, Karenza, Nomoto, Kenichi, Nakamura, Seigo, Saeki, Toshiaki, Watanabe, Junichiro, Perez-Garcia, Jose Manuel, Cortes, JavierEnlace del recurso
Publicado 2020
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46486“…We compared the dynamic format containing the three functions with the basic format in a randomized comparative study in 2803 children and 6289 caregivers in Japan. RESULTS: We found that the non-response alert lowered the item non-response rate (0.338% to 0.046%, t = − 4.411, p < 0.001 by generalized linear mixed model analysis). …”
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46487por Sakai, Yoshio, Fukunishi, Shinya, Takamura, Masayuki, Inoue, Oto, Takashima, Shinichiro, Usui, Soichiro, Seki, Akihiro, Nasti, Alessandro, Ho, Tuyen Thuy Bich, Kawaguchi, Kazunori, Asai, Akira, Tsuchimoto, Yusuke, Yamashita, Taro, Yamashita, Tatsuya, Mizukoshi, Eishiro, Honda, Masao, Imai, Yasuhito, Yoshimura, Kenichi, Murayama, Toshinori, Wada, Takashi, Harada, Kenichi, Higuchi, Kazuhide, Kaneko, Shuichi“…METHODS: Through consultation with the Japan Pharmaceuticals and Medical Devices Agency, we designed a clinical trial to assess a therapy for liver cirrhosis based on autologous adipose tissue-derived regenerative (stem) cells, which are extracted using an adipose tissue dissociation device. …”
Publicado 2020
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46488“…METHODS: In this cross-sectional study of 342 people with T2D, the Japan National Health and Wellness Survey (NHWS) database 2016 were used. …”
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46489por Merino, Nancy, Kawai, Mikihiko, Boyd, Eric S., Colman, Daniel R., McGlynn, Shawn E., Nealson, Kenneth H., Kurokawa, Ken, Hongoh, Yuichi“…In this study, we investigated the microbiota of Hakuba Happo hot springs (∼50°C; pH∼10.5–11), located in Nagano (Japan), which are impacted by the serpentinization process. …”
Publicado 2020
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46490por Miyake, Makito, Tanaka, Nobumichi, Asakawa, Isao, Yamaki, Kaori, Inoue, Takashi, Suzuki, Shota, Hori, Shunta, Nakai, Yasushi, Anai, Satoshi, Torimoto, Kazumasa, Toritsuka, Michihiro, Nakagawa, Hitoshi, Tsukamoto, Shinji, Fujii, Tomomi, Ohbayashi, Chiho, Hasegawa, Masatoshi, Kasahara, Masato, Fujimoto, Kiyohide“…TRIAL REGISTRATION: This clinical trial was prospectively registered with the Japan Registry of Clinical Trials on 5 December 2019. …”
Publicado 2020
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46491“…METHODS: We used the primers and single-quencher probes recommended by the CDC (N1, N2 and N3) in the USA and the NIID (N1 and N2) in Japan. In addition, we designed double-quencher probes according to the virus sequence provided by the NIID to develop a further assay (termed the YCH assay [N1 and N2]). …”
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46492por Wai, Kyi Mar, Sawada, Kaori, Kumagai, Mika, Itai, Kazuyoshi, Tokuda, Itoyo, Murashita, Koichi, Nakaji, Shigeyuki, Ihara, Kazushige“…Participants were 1176 community dwellers (>18 years) residing in the Iwaki District, Aomori Prefecture, Japan. We assessed the data of serum trace elements concentrations of cadmium (Cd), cobalt (Co), copper (Cu), selenium (Se), zinc (Zn), and iron (Fe) as well as the hematological parameters of red blood cells (RBC) counts, hemoglobin, packed cells volume (PCV), mean corpuscular volume (MCV), and mean corpuscular hemoglobin (MCH). …”
Publicado 2020
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46493“…The psychometric properties of the COHIP-SF 19 JP were assessed in 379 public school students between 7 and 18 years of age in Fukuoka, Japan. Internal consistency (Cronbach’s alpha) and test-retest reliability (intraclass correlation coefficient, ICC) were the metrics used for evaluation of this questionnaire. …”
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46494por Torimoto, Kazumasa, Miyake, Makito, Nakai, Yasushi, Aoki, Katsuya, Tanaka, Nobumichi, Fujimoto, Kiyohide“…TRIAL REGISTRATION: The Japan Registry of Clinical Trials (jRCTs051190080). …”
Publicado 2020
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46495por Tsekrekos, Andrianos, Triantafyllou, Tania, Klevebro, Fredrik, Hayami, Masaru, Lindblad, Mats, Nilsson, Magnus, Lundell, Lars, Rouvelas, Ioannis“…This process was facilitated by a close collaboration with two high-volume centers in Japan, as well as exchanging fellowships and observerships between the Karolinska University Hospital and other European centers. …”
Publicado 2020
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46496por Moreno-Agostino, Darío, Daskalopoulou, Christina, Wu, Yu-Tzu, Koukounari, Artemis, Haro, Josep Maria, Tyrovolas, Stefanos, Panagiotakos, Demosthenes B., Prince, Martin, Prina, A. Matthew“…METHODS: Based on a harmonised dataset of eight ageing cohorts in Australia, USA, Mexico, Japan, South Korea, and Europe, comprising 130,521 older adults (M(age) = 62.81, SD(age) = 10.06) followed-up up to 10 years (M(follow-up) = 5.47, SD(follow-up) = 3.22), we employed growth mixture modelling to identify latent classes of people with different trajectories of healthy ageing scores, which incorporated 41 items of health and functioning. …”
Publicado 2020
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46497“…Results With the NanoPass® 32.5-gauge, 6-mm needle (Terumo Corp., Tokyo, Japan), patients had significantly lower glycated hemoglobin (HbA1c) compared to 8-mm needles (7.9% vs. 8.3%; p<0.001). …”
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46498por Tekedar, Hasan C., Arick, Mark A., Hsu, Chuan-Yu, Thrash, Adam, Blom, Jochen, Lawrence, Mark L., Abdelhamed, Hossam“…Phylogenetic analysis showed a close relationship between MS-17-88 and strain Ae5 isolated from fish in China and ARB3 strain isolated from pond water in Japan, indicating a common ancestor of these strains. …”
Publicado 2020
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46499“…Second, the completion rate of non-cardiac surgery and interval between the two cardiac and non-cardiac operations were compared between surgical aortic valve replacement (AVR) patients before the introduction of TAVR (pre-AVR group (n = 10)), in AVR patients after the introduction of TAVR (post-AVR (n = 12)), and in TAVR patients (TAVR group (n = 12)). RESULTS: Age and Japan score were higher in the post-TAVR group than in the pre-TAVR group. …”
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46500por Izumi, Motohiro, Suzumura, Tomohiro, Ogawa, Koichi, Matsumoto, Yoshiya, Sawa, Kenji, Yoshimoto, Naoki, Tani, Yoko, Watanabe, Tetsuya, Kaneda, Hiroyasu, Mitsuoka, Shigeki, Asai, Kazuhisa, Kawaguchi, Tomoya“…METHODS: To clarify the differences in genetic mutation profiles between Caucasian and Japanese subjects, we compared data from The Cancer Genome Atlas, which mainly included Caucasians, with results from the Japan Molecular Epidemiology for lung cancer study, which is an epidemiological study only involving Japanese subjects. …”
Publicado 2020
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