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46661por Tokunaga, Mamoru, Okimoto, Kenichiro, Akizue, Naoki, Ishikawa, Kentaro, Hirotsu, Yosuke, Amemiya, Kenji, Ota, Masayuki, Matsusaka, Keisuke, Nishimura, Motoi, Matsushita, Kazuyuki, Ishikawa, Tsubasa, Nagashima, Ariki, Shiratori, Wataru, Kaneko, Tatsuya, Oura, Hirotaka, Kanayama, Kengo, Ohta, Yuki, Taida, Takashi, Saito, Keiko, Matsumura, Tomoaki, Chiba, Tetsuhiro, Mochizuki, Hitoshi, Arai, Makoto, Kato, Jun, Ikeda, Jun-ichiro, Omata, Masao, Kato, Naoya“…This study aims to investigate the genetic characteristics from nondysplastic BE (NDBE) to early EAC in Japan. Clinical information was collected. Moreover, the genetic profile of NDBE without concurrent dysplasia, early EAC, and surrounding BE were also investigated using endoscopic biopsy samples and formalin-fixed, paraffin-embedded specimens from Japanese patients by targeted next-generation sequencing. …”
Publicado 2021
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46662por Takeda, Koichi, Harada, Sohei, Hayama, Brian, Hoashi, Kosuke, Enokida, Taisuke, Sasaki, Toshiharu, Okamoto, Koh, Nakano, Kenji, Ohkushi, Daisuke“…METHODS: We retrospectively reviewed the medical records of patients with solid tumors diagnosed with PCP between 2006 and 2018 at a cancer center in Tokyo, Japan. Demographic and clinical data were collected, which included malignancy types, total lymphocyte count, coexisting pulmonary disease, chemotherapy, radiation therapy, corticosteroid use, and PCP-attributable mortality. …”
Publicado 2021
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46663por Taira, Naruto, Kashiwabara, Kosuke, Tsurutani, Junji, Kitada, Masahiro, Takahashi, Masato, Kato, Hiroaki, Kikawa, Yuichiro, Sakata, Eiko, Naito, Yoichi, Hasegawa, Yoshie, Saito, Tsuyoshi, Iwasa, Tsutomu, Takashima, Tsutomu, Aihara, Tomohiko, Mukai, Hirofumi, Hara, Fumikata“…TRIAL REGISTRATION: The protocol was registered at the website of the University Hospital Medical Information Network (UMIN), Japan (protocol ID: UMIN000015516), on 01/11/2014. …”
Publicado 2021
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46664“…The types of adverse events in both studies were similar to those in the preceding 8-week randomized, active-controlled studies in Japan, which were included in the application package for the approval of oral blonanserin for patients with schizophrenia. …”
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46665por Yan, Weihui, Xiao, Yongtao, Zhang, Yunyi, Tao, Yijing, Cao, Yi, Liu, Kunhui, Cai, Wei, Wang, Ying“…A review of the genetic variants of SLC26A3 reported in East Asia revealed that c.269_270 dupAA (p.G91Kfs*3) is the most frequent SLC26A3 mutation in China, compared with c.2063-1 G > T in Japan and Korea. EPCAM and MYO5B genetic variants were only sporadically reported in East Asia. …”
Publicado 2021
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46666“…All subjects underwent OCTA (DRI OCT Triton; Topcon Corporation, Tokyo, Japan) and peripapillary retinal nerve fiber layer (RNFL) thickness imaging with swept-source optical coherence tomography (OCT). …”
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46667por Yoshimura, Akihiro, Yamada, Tadaaki, Okuma, Yusuke, Fukuda, Akito, Watanabe, Satoshi, Nishioka, Naoya, Takeda, Takayuki, Chihara, Yusuke, Takemoto, Shinnosuke, Harada, Taishi, Hiranuma, Osamu, Shirai, Yukina, Nishiyama, Akihiro, Yano, Seiji, Goto, Yasuhiro, Shiotsu, Shinsuke, Kunimasa, Kei, Morimoto, Yoshie, Iwasaku, Masahiro, Kaneko, Yoshiko, Uchino, Junji, Kenmotsu, Hirotsugu, Takahashi, Toshiaki, Takayama, Koichi“…METHODS: We prospectively assessed advanced NSCLC patients with EGFR mutations who were treated with osimertinib at 14 institutions in Japan between September 2019 and December 2020. Relationships between outcomes of osimertinib monotherapy and patients’ characteristics were reviewed. …”
Publicado 2021
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46668por Kuroda, Shunsuke, Matsumoto, Shingo, Sano, Takahide, Kitai, Takeshi, Yonetsu, Taishi, Kohsaka, Shun, Torii, Sho, Kishi, Takuya, Komuro, Issei, Hirata, Ken-ichi, Node, Koichi, Matsue, Yuya“…SETTING AND PARTICIPANTS: Hospitalised patients with COVID-19 and cardiovascular disease or coronary risk factors from January to May 2020 in 49 hospitals in Japan. MAIN OUTCOME MEASURES: Two different types of outcomes, in-hospital mortality and a composite outcome, defined as the need for invasive mechanical ventilation and mortality. …”
Publicado 2021
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46669por Xu, Wei, Liu, Wentao, Wang, Lingquan, He, Changyu, Lu, Sheng, Ni, Zhentian, Hua, Zichen, Zhu, Zhenglun, Sah, Birendra Kumar, Yang, Zhongyin, Zheng, Yanan, Feng, Runhua, Li, Chen, Yao, Xuexin, Chen, Mingmin, Yan, Chao, Yan, Min, Zhu, Zhenggang“…BACKGROUND: For gastric cancer (GC) with extensive lymph node metastasis (bulky N2 and/or para-aortic lymph node metastases), there is no standard therapy worldwide. In Japan, preoperative chemotherapy (PCT) followed by D2 gastrectomy plus para-aortic lymph node dissection (PAND) is considered the standard treatment for these patients. …”
Publicado 2021
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46670por Oeun, Bolrathanak, Hikoso, Shungo, Nakatani, Daisaku, Mizuno, Hiroya, Suna, Shinichiro, Kitamura, Tetsuhisa, Okada, Katsuki, Dohi, Tomoharu, Sotomi, Yohei, Kida, Hirota, Sunaga, Akihiro, Sato, Taiki, Nakagawa, Akito, Nakagawa, Yusuke, Hayashi, Takaharu, Yano, Masamichi, Tamaki, Shunsuke, Yasumura, Yoshio, Yamada, Takahisa, Sakata, Yasushi“…PARTICIPANTS AND SETTING: We assessed 851 discharged-alive patients in the PURSUIT-HFpEF registry who were initially hospitalised due to an acute decompensated HFpEF (EF≥50%) and elevated N-terminal-pro-brain natriuretic peptide (≥400 ng/L) at Osaka University Hospital and other 30 affiliated hospitals in the Kansai region of Japan. Patients received a urine dipstick test, and were divided into two groups according to the absence or presence of proteinuria. …”
Publicado 2021
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46671por Asai, Nobuhiro, Nakamura, Akiko, Sakanashi, Daisuke, Koita, Isao, Ohashi, Wataru, Kawamoto, Yuzuka, Miyazaki, Narimi, Ohno, Tomoko, Yamada, Atsuko, Chida, Sumie, Shibata, Yuichi, Shiota, Arufumi, Kato, Hideo, Hagihara, Mao, Yamagishi, Yuka, Ohta, Hirotoshi, Mikamo, Hiroshige“…A new SARS-CoV-2 diagnostic test (SmartAmp) was licensed in Japan in July 2021. This method, which enables us to diagnose COVID-19 as well as a gene mutation on the virus, is promising to reduce medical costs and staff labor. …”
Publicado 2022
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46672por Ramstad, Silje N., Wasteson, Yngvild, Lindstedt, Bjørn-Arne, Taxt, Arne M., Bjørnholt, Jørgen V., Brandal, Lin T., Bohlin, Jon“…We observed high sequence identity (>98%) and coverage (≥94%) between Norwegian O145:H25 Stx2a phages and publicly available Stx2a phages from O145:H25 and O145:H28 STEC, isolated from HUS cases in the USA and a hemorrhagic diarrhea case from Japan, respectively. However, low similarity was seen when comparing the Norwegian O145:H25 Stx2a phage to Stx2a phages from STEC of other serotypes. …”
Publicado 2021
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46673“…The study included 37 pairs of patients with cancer who received treatment in the cancer department of a university hospital in Japan and their family caregivers (n = 74). The primary end-point was the change in HRV before and during the intervention. …”
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46674por Akiyama, Nobu, Okamura, Takuho, Yoshida, Minoru, Kimura, Shun-ichi, Yano, Shingo, Yoshida, Isao, Kusaba, Hiroyuki, Takahashi, Kosuke, Fujita, Hiroyuki, Fukushima, Keitaro, Iwasaki, Hiromichi, Tamura, Kazuo, Saeki, Toshiaki, Takamatsu, Yasushi, Zenda, Sadamoto“…CONCLUSION: GL is estimated to be widely utilized, but some recommendations were not followed, presumably due to a mismatch with actual clinical practices in Japan.…”
Publicado 2021
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46675por Wang, Ziheng, Sato, Keizo, Nawrin, Saida Salima, Widatalla, Namareq Salah, Kimura, Yoshitaka, Nagatomi, Ryoichi“…Method: Office chairs installed with pressure sensors were provided to a total of 22 office workers (age = 43.4 ± 8.3 years) in Japan. Pressure sensors data were collected during working days and hours (from morning to evening). …”
Publicado 2021
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46676por Ye, Huizhen, Chen, Youyuan, Ye, Peiyi, Zhang, Yu, Liu, Xiaoyi, Xiao, Guanqing, Zhang, Zhe, Kong, Yaozhong, Liang, Gehao“…METHODS: The development and internal validation of prediction models used data from the CKD-ROUTE study in Japan, while the external validation set used data collected at the First People’s Hospital of Foshan in southern China from January 2013 to December 2018. …”
Publicado 2021
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46677por Hassan, Meher, Israr, Muhammad, Mansoor, Simeen, Hussain, Syeda Amna, Basheer, Faiza, Azizullah, Azizullah, Ur Rehman, Shafiq“…For cytological studies, 48 h grown mung bean seedlings root tips were used to prepare slides and studied for percent mitotic index (MI%) and to calculate percent C-mitosis, laggard, sticky and fragmented chromosomes, pictures were captured by a Nikon camera (DS-Fi 1 Japan) attached with a microscope. One-week grown mung seedlings were studied for growth traits, malondialdehyde (MDA), protein, proline and antioxidant enzymes. …”
Publicado 2021
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46678“…BACKGROUND: Japan has the largest population of older adults in the world; it is only growing as life expectancy increases worldwide. …”
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46679por Torii, Shotaro, Oishi, Wakana, Zhu, Yifan, Thakali, Ocean, Malla, Bikash, Yu, Zaizhi, Zhao, Bo, Arakawa, Chisato, Kitajima, Masaaki, Hata, Akihiko, Ihara, Masaru, Kyuwa, Shigeru, Sano, Daisuke, Haramoto, Eiji, Katayama, Hiroyuki“…The present study compared five PEG precipitation procedures, with different operational parameters, for the RT-qPCR-based whole process recovery efficiency of murine hepatitis virus (MHV), bacteriophage phi6, and pepper mild mottle virus (PMMoV), and molecular process recovery efficiency of murine norovirus using 34 raw wastewater samples collected in Japan. The five procedures yielded significantly different whole process recovery efficiency of MHV (0.070%–2.6%) and phi6 (0.071%–0.51%). …”
Publicado 2022
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46680por Ayabe, Kengo, Komiyama, Tomoyoshi, Hasegawa, Misaki, Sakai, Tetsuri, Morise, Masahiro, Sakama, Susumu, Yagishita, Atsuhiko, Amino, Mari, Ikari, Yuji, Yoshioka, Koichiro“…We reviewed the charts of 101 patients who underwent HUTT at Tokai University Hospital in Japan between January 2016 and March 2019. During the HUTT, 72 patients (69.2%) experienced syncope. …”
Publicado 2021
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