Combined IL-2, agonistic CD3 and 4-1BB stimulation preserve clonotype hierarchy in propagated non-small cell lung cancer tumor-infiltrating lymphocytes

por Shah, Parin, Forget, Marie-Andrée, Frank, Meredith L, Jiang, Peixin, Sakellariou-Thompson, Donastas, Federico, Lorenzo, Khairullah, Roohussaba, Neutzler, Chantal Alexia, Wistuba, Ignacio, Chow, Chi-Wan B, Long, Yan, Fujimoto, Junya, Lin, Shiaw-Yih, Maitra, Anirban, Negrao, Marcelo V, Mitchell, Kyle Gregory, Weissferdt, Annikka, Vaporciyan, Ara A, Cascone, Tina, Roth, Jack A, Zhang, Jianjun, Sepesi, Boris, Gibbons, Don L, Heymach, John V, Haymaker, Cara L, McGrail, Daniel J, Reuben, Alexandre, Bernatchez, Chantale
Publicado 2022

Acidosis significantly alters immune checkpoint expression profiles of T cells from oesophageal adenocarcinoma patients

por Davern, Maria, Donlon, Noel E., O’Connell, Fiona, Gaughan, Caoimhe, O’Donovan, Cillian, Habash, Mohammed, Sheppard, Andrew D., MacLean, Michael, Dunne, Margaret R., Moore, Jenny, Temperley, Hugo, Conroy, Melissa J., Butler, Christine, Bhardwaj, Anshul, Ravi, Narayanasamy, Donohoe, Claire L., Reynolds, John V., Lysaght, Joanne
Publicado 2022

First-in-human phase I study of the OX40 agonist GSK3174998 with or without pembrolizumab in patients with selected advanced solid tumors (ENGAGE-1)

por Postel-Vinay, Sophie, Lam, Vincent K, Ros, Willeke, Bauer, Todd M, Hansen, Aaron R, Cho, Daniel C, Stephen Hodi, F, Schellens, Jan H M, Litton, Jennifer K, Aspeslagh, Sandrine, Autio, Karen A, Opdam, Frans L, McKean, Meredith, Somaiah, Neeta, Champiat, Stephane, Altan, Mehmet, Spreafico, Anna, Rahma, Osama, Paul, Elaine M, Ahlers, Christoph M, Zhou, Helen, Struemper, Herbert, Gorman, Shelby A, Watmuff, Maura, Yablonski, Kaitlin M, Yanamandra, Niranjan, Chisamore, Michael J, Schmidt, Emmett V, Hoos, Axel, Marabelle, Aurelien, Weber, Jeffrey S, Heymach, John V
Publicado 2023

Energy Metabolism, Metabolite, and Inflammatory Profiles in Human Ex Vivo Adipose Tissue Are Influenced by Obesity Status, Metabolic Dysfunction, and Treatment Regimes in Patients...

por O’Connell, Fiona, Mylod, Eimear, Donlon, Noel E., Heeran, Aisling B., Butler, Christine, Bhardwaj, Anshul, Ramjit, Sinead, Durand, Michael, Lambe, Gerard, Tansey, Paul, Welartne, Ivan, Sheahan, Kevin P., Yin, Xiaofei, Donohoe, Claire L., Ravi, Narayanasamy, Dunne, Margaret R., Brennan, Lorraine, Reynolds, John V., Roche, Helen M., O’Sullivan, Jacintha
Publicado 2023

Nutrient deprivation and hypoxia alter T cell immune checkpoint expression: potential impact for immunotherapy

por Davern, Maria, Donlon, Noel E., O’Connell, Fiona, Gaughan, Caoimhe, O’Donovan, Cillian, McGrath, Jason, Sheppard, Andrew D., Hayes, Conall, King, Ross, Temperley, Hugo, MacLean, Michael, Bulter, Christine, Bhardwaj, Anshul, Moore, Jenny, Donohoe, Claire, Ravi, Narayanasamy, Conroy, Melissa J., Reynolds, John V., Lysaght, Joanne
Publicado 2022

Visceral adipose tissue secretome from early and late-stage oesophageal cancer patients differentially affects effector and regulatory T cells

por Davern, Maria, Bracken-Clarke, Dara, Donlon, Noel E., Sheppard, Andrew D., Connell, Fiona O’, Heeran, Aisling B., Majcher, Klaudia, Conroy, Melissa J., Mylod, Eimear, Butler, Christine, Donohoe, Claire, Donnell, Dearbhaile O’, Lowery, Maeve, Bhardwaj, Anshul, Ravi, Narayanasamy, Melo, Ashanty A., Sullivan, Jacintha O’, Reynolds, John V., Lysaght, Joanne
Publicado 2023

Incidence and Transmission of SARS-CoV-2 in US Child Care Centers After COVID-19 Vaccines

por Shope, Timothy R., Chedid, Khalil, Hashikawa, Andrew N., Martin, Emily T., Sieber, Mary Ann, Des Ruisseau, Gabrielle, Williams, John V., Wheeler, Sarah E., Johnson, Monika, Stiegler, Myla, D’Agostino, Helen, Balasubramani, G. K., Yahner, Kristin A., Wang-Erickson, Anna F.
Publicado 2023

Polymorphisms Near TBX5 and GDF7 Are Associated With Increased Risk for Barrett’s Esophagus

por Palles, Claire, Chegwidden, Laura, Li, Xinzhong, Findlay, John M., Farnham, Garry, Castro Giner, Francesc, Peppelenbosch, Maikel P., Kovac, Michal, Adams, Claire L., Prenen, Hans, Briggs, Sarah, Harrison, Rebecca, Sanders, Scott, MacDonald, David, Haigh, Chris, Tucker, Art, Love, Sharon, Nanji, Manoj, deCaestecker, John, Ferry, David, Rathbone, Barrie, Hapeshi, Julie, Barr, Hugh, Moayyedi, Paul, Watson, Peter, Zietek, Barbara, Maroo, Neera, Gay, Laura, Underwood, Tim, Boulter, Lisa, McMurtry, Hugh, Monk, David, Patel, Praful, Ragunath, Krish, Al Dulaimi, David, Murray, Iain, Koss, Konrad, Veitch, Andrew, Trudgill, Nigel, Nwokolo, Chuka, Rembacken, Bjorn, Atherfold, Paul, Green, Elaine, Ang, Yeng, Kuipers, Ernst J., Chow, Wu, Paterson, Stuart, Kadri, Sudarshan, Beales, Ian, Grimley, Charles, Mullins, Paul, Beckett, Conrad, Farrant, Mark, Dixon, Andrew, Kelly, Sean, Johnson, Matthew, Wajed, Shahjehan, Dhar, Anjan, Sawyer, Elinor, Roylance, Rebecca, Onstad, Lynn, Gammon, Marilie D., Corley, Douglas A., Shaheen, Nicholas J., Bird, Nigel C., Hardie, Laura J., Reid, Brian J., Ye, Weimin, Liu, Geoffrey, Romero, Yvonne, Bernstein, Leslie, Wu, Anna H., Casson, Alan G., Fitzgerald, Rebecca, Whiteman, David C., Risch, Harvey A., Levine, David M., Vaughan, Tom L., Verhaar, Auke P., van den Brande, Jan, Toxopeus, Eelke L., Spaander, Manon C., Wijnhoven, Bas P.L., van der Laan, Luc J.W., Krishnadath, Kausilia, Wijmenga, Cisca, Trynka, Gosia, McManus, Ross, Reynolds, John V., O’Sullivan, Jacintha, MacMathuna, Padraic, McGarrigle, Sarah A., Kelleher, Dermot, Vermeire, Severine, Cleynen, Isabelle, Bisschops, Raf, Tomlinson, Ian, Jankowski, Janusz
Publicado 2015

Respiratory Syncytial Virus-Associated Hospitalizations in Young Children in the United States, 2015–2016

por Rha, Brian, Campbell, Angela P, McDaniel, Darius, Weinberg, Geoffrey A, Staat, Mary A, Selvarangan, Rangaraj, Halasa, Natasha B, Englund, Janet, Boom, Julie A, Azimi, Parvin H, Williams, John V, Szilagyi, Peter G, Singer, Monica N, Munoz, Flor M, Mcneal, Monica, Klein, Eileen J, Harrison, Christopher J, Figueroa-Downing, Daniella, Yu, Joana, Prill, Mila M, Whitaker, Brett L, Curns, Aaron T, Payne, Daniel C, Gerber, Susan I
Publicado 2017

751. Acute Respiratory Illness Hospitalizations Among Young Children: Multi-Center Viral Surveillance Network, United States, 2015–2016

por Rha, Brian, Campbell, Angela P, McDaniel, Darius, Selvarangan, Rangaraj, Halasa, Natasha, Englund, Janet, Boom, Julie A, Azimi, Parvin H, Weinberg, Geoffrey A, Staat, Mary A, Singer, Monica N, Sahni, Leila C, McNeal, Monica, Klein, Eileen J, Harrison, Christopher J, Williams, John V, Yu, Joana, Figueroa-Downing, Daniella, Prill, Mila M, Whitaker, Brett L, Curns, Aaron T, Langley, Gayle E, Payne, Daniel C, Gerber, Susan I
Publicado 2018

Association of Long-term Outcomes and Survival With Multidisciplinary Salvage Treatment for Local and Regional Recurrence After Stereotactic Ablative Radiotherapy for Early-Stage L...

por Brooks, Eric D., Sun, Bing, Feng, Lei, Verma, Vivek, Zhao, Lina, Gomez, Daniel R., Liao, Zhongxing, Jeter, Melenda, O’Reilly, Michael, Welsh, James W., Nguyen, Quynh-Nhu, Erasmus, Jeremy J., Eapen, George, Ahrar, Kamran, Antonoff, Mara B., Hahn, Stephen M., Heymach, John V., Rice, David C., Chang, Joe Y.
Publicado 2018

Contextual Factors Associated With County-Level Suicide Rates in the United States, 1999 to 2016

por Steelesmith, Danielle L., Fontanella, Cynthia A., Campo, John V., Bridge, Jeffrey A., Warren, Keith L., Root, Elisabeth D.
Publicado 2019

Expert consensus statements for the management of COVID-19-related acute respiratory failure using a Delphi method

por Nasa, Prashant, Azoulay, Elie, Khanna, Ashish K., Jain, Ravi, Gupta, Sachin, Javeri, Yash, Juneja, Deven, Rangappa, Pradeep, Sundararajan, Krishnaswamy, Alhazzani, Waleed, Antonelli, Massimo, Arabi, Yaseen M., Bakker, Jan, Brochard, Laurent J., Deane, Adam M., Du, Bin, Einav, Sharon, Esteban, Andrés, Gajic, Ognjen, Galvagno, Samuel M., Guérin, Claude, Jaber, Samir, Khilnani, Gopi C., Koh, Younsuck, Lascarrou, Jean-Baptiste, Machado, Flavia R., Malbrain, Manu L. N. G., Mancebo, Jordi, McCurdy, Michael T., McGrath, Brendan A., Mehta, Sangeeta, Mekontso-Dessap, Armand, Mer, Mervyn, Nurok, Michael, Park, Pauline K., Pelosi, Paolo, Peter, John V., Phua, Jason, Pilcher, David V., Piquilloud, Lise, Schellongowski, Peter, Schultz, Marcus J., Shankar-Hari, Manu, Singh, Suveer, Sorbello, Massimiliano, Tiruvoipati, Ravindranath, Udy, Andrew A., Welte, Tobias, Myatra, Sheila N.
Publicado 2021

Genetic and non-genetic factors affecting the expression of COVID-19-relevant genes in the large airway epithelium

por Kasela, Silva, Ortega, Victor E., Martorella, Molly, Garudadri, Suresh, Nguyen, Jenna, Ampleford, Elizabeth, Pasanen, Anu, Nerella, Srilaxmi, Buschur, Kristina L., Barjaktarevic, Igor Z., Barr, R. Graham, Bleecker, Eugene R., Bowler, Russell P., Comellas, Alejandro P., Cooper, Christopher B., Couper, David J., Criner, Gerard J., Curtis, Jeffrey L., Han, MeiLan K., Hansel, Nadia N., Hoffman, Eric A., Kaner, Robert J., Krishnan, Jerry A., Martinez, Fernando J., McDonald, Merry-Lynn N., Meyers, Deborah A., Paine, Robert, Peters, Stephen P., Castro, Mario, Denlinger, Loren C., Erzurum, Serpil C., Fahy, John V., Israel, Elliot, Jarjour, Nizar N., Levy, Bruce D., Li, Xingnan, Moore, Wendy C., Wenzel, Sally E., Zein, Joe, Langelier, Charles, Woodruff, Prescott G., Lappalainen, Tuuli, Christenson, Stephanie A.
Publicado 2021

Effects of Dietary Supplementation with Mushroom or Vitamin D(2)-Enriched Mushroom Powders on Gastrointestinal Health Parameters in the Weaned Pig

por Dowley, Alison, Sweeney, Torres, Conway, Eadaoin, Vigors, Stafford, Yadav, Supriya, Wilson, Jude, Gabrielli, William, O’Doherty, John V.
Publicado 2021

Phase I clinical trial evaluating the safety and efficacy of ADP-A2M10 SPEAR T cells in patients with MAGE-A10(+) advanced non-small cell lung cancer

por Blumenschein, George R, Devarakonda, Siddhartha, Johnson, Melissa, Moreno, Victor, Gainor, Justin, Edelman, Martin J, Heymach, John V, Govindan, Ramaswamy, Bachier, Carlos, Doger de Spéville, Bernard, Frigault, Matthew J, Olszanski, Anthony J, Lam, Vincent K, Hyland, Natalie, Navenot, Jean-Marc, Fayngerts, Svetlana, Wolchinsky, Zohar, Broad, Robyn, Batrakou, Dzmitry, Pentony, Melissa M, Sanderson, Joseph P, Gerry, Andrew, Marks, Diane, Bai, Jane, Holdich, Tom, Norry, Elliot, Fracasso, Paula M
Publicado 2022

Limited Benefit from the Addition of Immunotherapy to Chemotherapy in TKI-Refractory EGFR-Mutant Lung Adenocarcinoma

por Hong, Lingzhi, Lewis, Whitney E., Nilsson, Monique, Patel, Sonia, Varghese, Susan, Rivera, Melvin J., Du, Robyn R., Chen, Pingjun, Kemp, Haley N., Rinsurongkawong, Waree, Heeke, Simon, Spelman, Amy R., Elamin, Yasir Y., Negrao, Marcelo V., Sepesi, Boris, Gibbons, Don L., Lee, J. Jack, Wu, Jia, Vokes, Natalie I., Heymach, John V., Zhang, Jianjun, Le, Xiuning
Publicado 2022

The effects of dietary supplementation with mushroom or selenium enriched mushroom powders on the growth performance and intestinal health of post-weaned pigs

por Dowley, Alison, Sweeney, Torres, Conway, Eadaoin, Vigors, Stafford, Ryan, Marion T., Yadav, Supriya, Wilson, Jude, O’Doherty, John V.
Publicado 2023

Circulation of Rhinoviruses and/or Enteroviruses in Pediatric Patients With Acute Respiratory Illness Before and During the COVID-19 Pandemic in the US

por Rankin, Danielle A., Spieker, Andrew J., Perez, Ariana, Stahl, Anna L., Rahman, Herdi K., Stewart, Laura S., Schuster, Jennifer E., Lively, Joana Y., Haddadin, Zaid, Probst, Varvara, Michaels, Marian G., Williams, John V., Boom, Julie A., Sahni, Leila C., Staat, Mary A., Schlaudecker, Elizabeth P., McNeal, Monica M., Harrison, Christopher J., Weinberg, Geoffrey A., Szilagyi, Peter G., Englund, Janet A., Klein, Eileen J., Gerber, Susan I., McMorrow, Meredith, Rha, Brian, Chappell, James D., Selvarangan, Rangaraj, Midgley, Claire M., Halasa, Natasha B.
Publicado 2023

2098: Endogenous reverse transcriptase (LINE-1) in human platelets regulates cell morphology and protein synthetic events

por Schwertz, Hansjorg, Rowley, Jesse W., Kraiss, Larry W., Moran, John V., Campbell, Robert A., Zimmerman, Guy A., Weyrich, Andrew S., Thomas Rondina, Matthew, Schumann, Gerald G., Thorack, Ulrike
Publicado 2018