Safety, tolerability, pharmacokinetics, and activity of the novel long-acting antimalarial DSM265: a two-part first-in-human phase 1a/1b randomised study

por McCarthy, James S, Lotharius, Julie, Rückle, Thomas, Chalon, Stephan, Phillips, Margaret A, Elliott, Suzanne, Sekuloski, Silvana, Griffin, Paul, Ng, Caroline L, Fidock, David A, Marquart, Louise, Williams, Noelle S, Gobeau, Nathalie, Bebrevska, Lidiya, Rosario, Maria, Marsh, Kennan, Möhrle, Jörg J
Publicado 2017

Outcome of acute respiratory distress syndrome in university and non-university hospitals in Germany

por Raymondos, Konstantinos, Dirks, Tamme, Quintel, Michael, Molitoris, Ulrich, Ahrens, Jörg, Dieck, Thorben, Johanning, Kai, Henzler, Dietrich, Rossaint, Rolf, Putensen, Christian, Wrigge, Hermann, Wittich, Ralph, Ragaller, Maximilian, Bein, Thomas, Beiderlinden, Martin, Sanmann, Maxi, Rabe, Christian, Schlechtweg, Jörn, Holler, Monika, Frutos-Vivar, Fernando, Esteban, Andres, Hecker, Hartmut, Rosseau, Simone, von Dossow, Vera, Spies, Claudia, Welte, Tobias, Piepenbrock, Siegfried, Weber-Carstens, Steffen
Publicado 2017

A randomized phase II study of paclitaxel alone versus paclitaxel plus sorafenib in second- and third-line treatment of patients with HER2-negative metastatic breast cancer (PASO)

por Decker, Thomas, Overkamp, Friedrich, Rösel, Siegfried, Nusch, Arnd, Göhler, Thomas, Indorf, Martin, Sahlmann, Jörg, Trarbach, Tanja
Publicado 2017

Treatment outcome in early diffuse cutaneous systemic sclerosis: the European Scleroderma Observational Study (ESOS)

por Herrick, Ariane L, Pan, Xiaoyan, Peytrignet, Sébastien, Lunt, Mark, Hesselstrand, Roger, Mouthon, Luc, Silman, Alan, Brown, Edith, Czirják, László, Distler, Jörg H W, Distler, Oliver, Fligelstone, Kim, Gregory, William J, Ochiel, Rachel, Vonk, Madelon, Ancuţa, Codrina, Ong, Voon H, Farge, Dominique, Hudson, Marie, Matucci-Cerinic, Marco, Balbir-Gurman, Alexandra, Midtvedt, Øyvind, Jordan, Alison C, Jobanputra, Paresh, Stevens, Wendy, Moinzadeh, Pia, Hall, Frances C, Agard, Christian, Anderson, Marina E, Diot, Elisabeth, Madhok, Rajan, Akil, Mohammed, Buch, Maya H, Chung, Lorinda, Damjanov, Nemanja, Gunawardena, Harsha, Lanyon, Peter, Ahmad, Yasmeen, Chakravarty, Kuntal, Jacobsen, Søren, MacGregor, Alexander J, McHugh, Neil, Müller-Ladner, Ulf, Riemekasten, Gabriela, Becker, Michael, Roddy, Janet, Carreira, Patricia E, Fauchais, Anne Laure, Hachulla, Eric, Hamilton, Jennifer, İnanç, Murat, McLaren, John S, van Laar, Jacob M, Pathare, Sanjay, Proudman, Susannah, Rudin, Anna, Sahhar, Joanne, Coppere, Brigitte, Serratrice, Christine, Sheeran, Tom, Veale, Douglas J, Grange, Claire, Trad, Georges-Selim, Denton, Christopher P
Publicado 2017

Proteomic profiling of breast cancer metabolism identifies SHMT2 and ASCT2 as prognostic factors

por Bernhardt, Stephan, Bayerlová, Michaela, Vetter, Martina, Wachter, Astrid, Mitra, Devina, Hanf, Volker, Lantzsch, Tilmann, Uleer, Christoph, Peschel, Susanne, John, Jutta, Buchmann, Jörg, Weigert, Edith, Bürrig, Karl-Friedrich, Thomssen, Christoph, Korf, Ulrike, Beissbarth, Tim, Wiemann, Stefan, Kantelhardt, Eva Johanna
Publicado 2017

Translational evidence for two distinct patterns of neuroaxonal injury in sepsis: a longitudinal, prospective translational study

por Ehler, Johannes, Barrett, Lucinda K., Taylor, Valerie, Groves, Michael, Scaravilli, Francesco, Wittstock, Matthias, Kolbaske, Stephan, Grossmann, Annette, Henschel, Jörg, Gloger, Martin, Sharshar, Tarek, Chretien, Fabrice, Gray, Francoise, Nöldge-Schomburg, Gabriele, Singer, Mervyn, Sauer, Martin, Petzold, Axel
Publicado 2017

The effect of guided self-determination on self-management in persons with type 1 diabetes mellitus and HbA(1c) ≥64 mmol/mol: a group-based randomised controlled trial

por Mohn, Jannike, Graue, Marit, Assmus, Jõrg, Zoffmann, Vibeke, Thordarson, Hrafnkell, Peyrot, Mark, Rokne, Berit
Publicado 2017

Interest in Integrative Medicine Among Postmenopausal Hormone Receptor–Positive Breast Cancer Patients in the EvAluate-TM Study

por Hack, Carolin C., Fasching, Peter A., Fehm, Tanja, de Waal, Johann, Rezai, Mahdi, Baier, Bernd, Baake, Gerold, Kolberg, Hans-Christian, Guggenberger, Martin, Warm, Mathias, Harbeck, Nadia, Wuerstlein, Rachel, Deuker, Jörg-Uwe, Dall, Peter, Richter, Barbara, Wachsmann, Grischa, Brucker, Cosima, Siebers, Jan W., Fersis, Nikos, Kuhn, Thomas, Wolf, Christopher, Vollert, Hans-Walter, Breitbach, Georg-Peter, Janni, Wolfgang, Landthaler, Robert, Kohls, Andreas, Rezek, Daniela, Noesslet, Thomas, Fischer, Gunnar, Henschen, Stefan, Praetz, Thomas, Heyl, Volker, Kühn, Thorsten, Krauss, Thomas, Thomssen, Christoph, Hohn, Andre, Tesch, Hans, Mundhenke, Christoph, Hein, Alexander, Rauh, Claudia, Bayer, Christian M., Jacob, Adib, Schmidt, Katja, Belleville, Erik, Hadji, Peyman, Brucker, Sara Y., Wallwiener, Diethelm, Kümmel, Sherko, Beckmann, Matthias W., Paepke, Daniela
Publicado 2016

Habitat properties are key drivers of Borrelia burgdorferi (s.l.) prevalence in Ixodes ricinus populations of deciduous forest fragments

por Ehrmann, Steffen, Ruyts, Sanne C., Scherer-Lorenzen, Michael, Bauhus, Jürgen, Brunet, Jörg, Cousins, Sara A. O., Deconchat, Marc, Decocq, Guillaume, De Frenne, Pieter, De Smedt, Pallieter, Diekmann, Martin, Gallet-Moron, Emilie, Gärtner, Stefanie, Hansen, Karin, Kolb, Annette, Lenoir, Jonathan, Lindgren, Jessica, Naaf, Tobias, Paal, Taavi, Panning, Marcus, Prinz, Maren, Valdés, Alicia, Verheyen, Kris, Wulf, Monika, Liira, Jaan
Publicado 2018

Lorlatinib in ALK- or ROS1-rearranged non-small cell lung cancer: an international, multicenter, open-label phase 1 trial

por Shaw, Alice T., Felip, Enriqueta, Bauer, Todd M., Besse, Benjamin, Navarro, Alejandro, Postel-Vinay, Sophie, Gainor, Justin F., Johnson, Melissa, Dietrich, Jorg, James, Leonard P., Clancy, Jill S., Chen, Joseph, Martini, Jean-François, Abbattista, Antonello, Solomon, Benjamin J.
Publicado 2017

Patterns and predictors of skin score change in early diffuse systemic sclerosis from the European Scleroderma Observational Study

por Herrick, Ariane L, Peytrignet, Sebastien, Lunt, Mark, Pan, Xiaoyan, Hesselstrand, Roger, Mouthon, Luc, Silman, Alan J, Dinsdale, Graham, Brown, Edith, Czirják, László, Distler, Jörg H W, Distler, Oliver, Fligelstone, Kim, Gregory, William J, Ochiel, Rachel, Vonk, Madelon C, Ancuţa, Codrina, Ong, Voon H, Farge, Dominique, Hudson, Marie, Matucci-Cerinic, Marco, Balbir-Gurman, Alexandra, Midtvedt, Øyvind, Jobanputra, Paresh, Jordan, Alison C, Stevens, Wendy, Moinzadeh, Pia, Hall, Frances C, Agard, Christian, Anderson, Marina E, Diot, Elisabeth, Madhok, Rajan, Akil, Mohammed, Buch, Maya H, Chung, Lorinda, Damjanov, Nemanja S, Gunawardena, Harsha, Lanyon, Peter, Ahmad, Yasmeen, Chakravarty, Kuntal, Jacobsen, Søren, MacGregor, Alexander J, McHugh, Neil, Müller-Ladner, Ulf, Riemekasten, Gabriela, Becker, Michael, Roddy, Janet, Carreira, Patricia E, Fauchais, Anne Laure, Hachulla, Eric, Hamilton, Jennifer, İnanç, Murat, McLaren, John S, van Laar, Jacob M, Pathare, Sanjay, Proudman, Susanna M, Rudin, Anna, Sahhar, Joanne, Coppere, Brigitte, Serratrice, Christine, Sheeran, Tom, Veale, Douglas J, Grange, Claire, Trad, Georges-Selim, Denton, Christopher P
Publicado 2018

Association genetics studies on frost tolerance in wheat (Triticum aestivum L.) reveal new highly conserved amino acid substitutions in CBF-A3, CBF-A15, VRN3 and PPD1 genes

por Babben, Steve, Schliephake, Edgar, Janitza, Philipp, Berner, Thomas, Keilwagen, Jens, Koch, Michael, Arana-Ceballos, Fernando Alberto, Templer, Sven Eduard, Chesnokov, Yuriy, Pshenichnikova, Tatyana, Schondelmaier, Jörg, Börner, Andreas, Pillen, Klaus, Ordon, Frank, Perovic, Dragan
Publicado 2018

Rationale and Plan for Vitamin D Food Fortification: A Review and Guidance Paper

por Pilz, Stefan, März, Winfried, Cashman, Kevin D., Kiely, Mairead E., Whiting, Susan J., Holick, Michael F., Grant, William B., Pludowski, Pawel, Hiligsmann, Mickael, Trummer, Christian, Schwetz, Verena, Lerchbaum, Elisabeth, Pandis, Marlene, Tomaschitz, Andreas, Grübler, Martin R., Gaksch, Martin, Verheyen, Nicolas, Hollis, Bruce W., Rejnmark, Lars, Karras, Spyridon N., Hahn, Andreas, Bischoff-Ferrari, Heike A., Reichrath, Jörg, Jorde, Rolf, Elmadfa, Ibrahim, Vieth, Reinhold, Scragg, Robert, Calvo, Mona S., van Schoor, Natasja M., Bouillon, Roger, Lips, Paul, Itkonen, Suvi T., Martineau, Adrian R., Lamberg-Allardt, Christel, Zittermann, Armin
Publicado 2018

Improved lung recruitment and oxygenation during mandatory ventilation with a new expiratory ventilation assistance device: A controlled interventional trial in healthy pigs

por Schmidt, Johannes, Wenzel, Christin, Mahn, Marlene, Spassov, Sashko, Cristina Schmitz, Heidi, Borgmann, Silke, Lin, Ziwei, Haberstroh, Jörg, Meckel, Stephan, Eiden, Sebastian, Wirth, Steffen, Buerkle, Hartmut, Schumann, Stefan
Publicado 2018

Tracking Five Millennia of Horse Management with Extensive Ancient Genome Time Series

por Fages, Antoine, Hanghøj, Kristian, Khan, Naveed, Gaunitz, Charleen, Seguin-Orlando, Andaine, Leonardi, Michela, McCrory Constantz, Christian, Gamba, Cristina, Al-Rasheid, Khaled A.S., Albizuri, Silvia, Alfarhan, Ahmed H., Allentoft, Morten, Alquraishi, Saleh, Anthony, David, Baimukhanov, Nurbol, Barrett, James H., Bayarsaikhan, Jamsranjav, Benecke, Norbert, Bernáldez-Sánchez, Eloísa, Berrocal-Rangel, Luis, Biglari, Fereidoun, Boessenkool, Sanne, Boldgiv, Bazartseren, Brem, Gottfried, Brown, Dorcas, Burger, Joachim, Crubézy, Eric, Daugnora, Linas, Davoudi, Hossein, de Barros Damgaard, Peter, de los Ángeles de Chorro y de Villa-Ceballos, María, Deschler-Erb, Sabine, Detry, Cleia, Dill, Nadine, do Mar Oom, Maria, Dohr, Anna, Ellingvåg, Sturla, Erdenebaatar, Diimaajav, Fathi, Homa, Felkel, Sabine, Fernández-Rodríguez, Carlos, García-Viñas, Esteban, Germonpré, Mietje, Granado, José D., Hallsson, Jón H., Hemmer, Helmut, Hofreiter, Michael, Kasparov, Aleksei, Khasanov, Mutalib, Khazaeli, Roya, Kosintsev, Pavel, Kristiansen, Kristian, Kubatbek, Tabaldiev, Kuderna, Lukas, Kuznetsov, Pavel, Laleh, Haeedeh, Leonard, Jennifer A., Lhuillier, Johanna, Liesau von Lettow-Vorbeck, Corina, Logvin, Andrey, Lõugas, Lembi, Ludwig, Arne, Luis, Cristina, Arruda, Ana Margarida, Marques-Bonet, Tomas, Matoso Silva, Raquel, Merz, Victor, Mijiddorj, Enkhbayar, Miller, Bryan K., Monchalov, Oleg, Mohaseb, Fatemeh A., Morales, Arturo, Nieto-Espinet, Ariadna, Nistelberger, Heidi, Onar, Vedat, Pálsdóttir, Albína H., Pitulko, Vladimir, Pitskhelauri, Konstantin, Pruvost, Mélanie, Rajic Sikanjic, Petra, Rapan Papeša, Anita, Roslyakova, Natalia, Sardari, Alireza, Sauer, Eberhard, Schafberg, Renate, Scheu, Amelie, Schibler, Jörg, Schlumbaum, Angela, Serrand, Nathalie, Serres-Armero, Aitor, Shapiro, Beth, Sheikhi Seno, Shiva, Shevnina, Irina, Shidrang, Sonia, Southon, John, Star, Bastiaan, Sykes, Naomi, Taheri, Kamal, Taylor, William, Teegen, Wolf-Rüdiger, Trbojević Vukičević, Tajana, Trixl, Simon, Tumen, Dashzeveg, Undrakhbold, Sainbileg, Usmanova, Emma, Vahdati, Ali, Valenzuela-Lamas, Silvia, Viegas, Catarina, Wallner, Barbara, Weinstock, Jaco, Zaibert, Victor, Clavel, Benoit, Lepetz, Sébastien, Mashkour, Marjan, Helgason, Agnar, Stefánsson, Kári, Barrey, Eric, Willerslev, Eske, Outram, Alan K., Librado, Pablo, Orlando, Ludovic
Publicado 2019

Seroprevalence and Current Infections of Canine Vector-Borne Diseases in Costa Rica

por Springer, Andrea, Montenegro, Víctor M., Schicht, Sabine, Globokar Vrohvec, Majda, Pantchev, Nikola, Balzer, Jörg, Strube, Christina
Publicado 2019

Noninvasive assessment and quantification of tumor vascularization using [18F]FDG-PET/CT and CE-CT in a tumor model with modifiable angiogenesis—an animal experimental prospective...

por Mirus, Martin, Tokalov, Sergey V., Abramyuk, Andrij, Heinold, Jessica, Prochnow, Vincent, Zöphel, Klaus, Kotzerke, Jörg, Abolmaali, Nasreddin
Publicado 2019

Perioperative redistribution of regional ventilation and pulmonary function: a prospective observational study in two cohorts of patients at risk for postoperative pulmonary compli...

por Bauer, Maria, Opitz, Anne, Filser, Jörg, Jansen, Hendrik, Meffert, Rainer H., Germer, Christoph T., Roewer, Norbert, Muellenbach, Ralf M., Kredel, Markus
Publicado 2019

The Scales Project, a cross-national dataset on the interpretation of thermal perception scales

por Schweiker, Marcel, Abdul-Zahra, Amar, André, Maíra, Al-Atrash, Farah, Al-Khatri, Hanan, Alprianti, Rea Risky, Alsaad, Hayder, Amin, Rucha, Ampatzi, Eleni, Arsano, Alpha Yacob, Azadeh, Montazami, Azar, Elie, Bahareh, Bannazadeh, Batagarawa, Amina, Becker, Susanne, Buonocore, Carolina, Cao, Bin, Choi, Joon-Ho, Chun, Chungyoon, Daanen, Hein, Damiati, Siti Aisyah, Daniel, Lyrian, Vecchi, Renata De, Dhaka, Shivraj, Domínguez-Amarillo, Samuel, Dudkiewicz, Edyta, Edappilly, Lakshmi Prabha, Fernández-Agüera, Jesica, Folkerts, Mireille, Frijns, Arjan, Gaona, Gabriel, Garg, Vishal, Gauthier, Stephanie, Jabbari, Shahla Ghaffari, Harimi, Djamila, Hellwig, Runa T., Huebner, Gesche M., Jin, Quan, Jowkar, Mina, Kania, Renate, Kim, Jungsoo, King, Nelson, Kingma, Boris, Koerniawan, M. Donny, Kolarik, Jakub, Kumar, Shailendra, Kwok, Alison, Lamberts, Roberto, Laska, Marta, Lee, M. C. Jeffrey, Lee, Yoonhee, Lindermayr, Vanessa, Mahaki, Mohammadbagher, Marcel-Okafor, Udochukwu, Marín-Restrepo, Laura, Marquardsen, Anna, Martellotta, Francesco, Mathur, Jyotirmay, McGill, Gráinne, Mino-Rodriguez, Isabel, Mou, Di, Moujalled, Bassam, Nakajima, Mia, Ng, Edward, Okafor, Marcellinus, Olweny, Mark, Ouyang, Wanlu, Papst de Abreu, Ana Ligia, Pérez-Fargallo, Alexis, Rajapaksha, Indrika, Ramos, Greici, Rashid, Saif, Reinhart, Christoph F., Rivera, Ma. Isabel, Salmanzadeh, Mazyar, Schakib-Ekbatan, Karin, Schiavon, Stefano, Shooshtarian, Salman, Shukuya, Masanori, Soebarto, Veronica, Suhendri, Tahsildoost, Mohammad, Tartarini, Federico, Teli, Despoina, Tewari, Priyam, Thapa, Samar, Trebilcock, Maureen, Trojan, Jörg, Tukur, Ruqayyatu B., Voelker, Conrad, Yam, Yeung, Yang, Liu, Zapata-Lancaster, Gabriela, Zhai, Yongchao, Zhu, Yingxin, Zomorodian, Zahra Sadat
Publicado 2019

RBP2 stabilizes slow Cav1.3 Ca(2+) channel inactivation properties of cochlear inner hair cells

por Ortner, Nadine J., Pinggera, Alexandra, Hofer, Nadja T., Siller, Anita, Brandt, Niels, Raffeiner, Andrea, Vilusic, Kristina, Lang, Isabelle, Blum, Kerstin, Obermair, Gerald J., Stefan, Eduard, Engel, Jutta, Striessnig, Jörg
Publicado 2019