Mostrando 21 - 40 Resultados de 122 Para Buscar '"KLC"', tiempo de consulta: 0.09s Limitar resultados
  1. 21
    “…A 2.1-kb plasmid was previously isolated from Weissella cibaria KLC140 in kimchi and cloned into pUC19 along with the slpA and gfp genes, resulting in an 8.6-kb pKWCSLGFP construct for use as a novel surface display vector. …”
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    Characterization of a minimal pKW2124 replicon from Weissella cibaria KLC140 and its application for the construction of the Weissella expression vector pKUCm1
  2. 22
    por Klc, Daniel
    Publicado 2013
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    Work report on summer student project
  3. 23
    “…Finally, we found that the patient had both hepatocyte growth factor receptor (MET) gene amplification and kinesin light chain 1-anaplastic lymphoma kinase fusion (KLC1-ALK) through next-generation sequencing and showed sensitivity to the targeted therapy of crizotinib. …”
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    Rapid response of brain metastasis to crizotinib in a patient with KLC1-ALK fusion and MET gene amplification positive non-small cell lung cancer: a case report
  4. 24
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    Direct measurement of fission barrier height of unstable heavy nuclei at ISOL facilities
  5. 25
    “…Conventional kinesin, kinesin-I, is a heterotetramer of two kinesin heavy chain (KHC) subunits (KIF5A, KIF5B, or KIF5C) and two kinesin light chain (KLC) subunits. While KHC contains the motor activity, the role of KLC remains unknown. …”
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    Defective Kinesin Heavy Chain Behavior in Mouse Kinesin Light Chain Mutants
  6. 26
    “…Kinesin light chain‐2 (KLC2) has been found to be upregulated in lung cancer and also to be associated with poor prognosis. …”
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    The kinesin light chain‐2, a target of mRNA stabilizing protein HuR, inhibits p53 protein phosphorylation to promote radioresistance in NSCLC
  7. 27
    por Biedler, James K, Tu, Zhijian
    Publicado 2010
    “…Unlike AaKLC2, AaKLC1 is expressed in all life stages and tissues tested, which is consistent with the expression pattern of the An. gambiae and D. melanogaster KLC genes. …”
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    Evolutionary analysis of the kinesin light chain genes in the yellow fever mosquito Aedes aegypti: gene duplication as a source for novel early zygotic genes
  8. 28
    “…Despite a high sequence identity between their TPR domains (87%), KLC1 and KLC2 isoforms exhibit differential binding properties towards some cargos. …”
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    Crystal Structures of the Tetratricopeptide Repeat Domains of Kinesin Light Chains: Insight into Cargo Recognition Mechanisms
  9. 29
    “…F12/E2 displaces 14‐3‐3 from KLC and, unlike 14‐3‐3, does not require phosphorylation of KLC for its binding. …”
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    Vaccinia virus proteins A36 and F12/E2 show strong preferences for different kinesin light chain isoforms
  10. 30
    “…Three treatment groups were given KLC (3.6 g/kg), KLC (7.2 g/kg), and finasteride (0.9 mg/kg), respectively, for 28 days after establishing the animal model. …”
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    Anti-Inflammatory and Antioxidant Effects of Kelong-Capsule on Testosterone-Induced Benign Prostatic Hyperplasia in Rats
  11. 31
    “…KLC4 was upregulated in human lung cancer cell lines. …”
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    Kinesin light chain-4 depletion induces apoptosis of radioresistant cancer cells by mitochondrial dysfunction via calcium ion influx
  12. 32
    “…Lastly, the enhancement of plaque size resulting from loss of KLC isoform 1 was abrogated by removal of KLC isoforms 1 and 2 simultaneously. …”
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    Vaccinia Virus Protein Complex F12/E2 Interacts with Kinesin Light Chain Isoform 2 to Engage the Kinesin-1 Motor Complex
  13. 33
    “…Mutations were generated in the Drosophila gene Kinesin light chain (Klc), and the phenotypic consequences of loss of Klc function were analyzed at the behavioral and cellular levels. …”
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    Kinesin Light Chains Are Essential for Axonal Transport in Drosophila
  14. 34
    “…Despite reduction of KLC1, undifferentiated hESC exhibited apparently normal colony morphology and pluripotency marker expression. …”
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    Kinesin Light Chain 1 Suppression Impairs Human Embryonic Stem Cell Neural Differentiation and Amyloid Precursor Protein Metabolism
  15. 35
    “…In addition, KLC4 and CHEK2 expression levels showed negative correlation in lung tumor samples from patients, and KLC4 overexpression correlated negatively with survival. …”
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    Kinesin light chain 4 as a new target for lung cancer chemoresistance via targeted inhibition of checkpoint kinases in the DNA repair network
  16. 36
    “…Keratosis lichenoides chronica (KLC) is a rare keratotic disorder of unknown origin. …”
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    A Mild Case of Adult-Onset Keratosis Lichenoides Chronica Successfully Treated with Narrow-Band UVB Monotherapy
  17. 37
    por Wang, M, Zhu, X, Sha, Z, Li, N, Li, D, Chen, L
    Publicado 2015
    “…Kinesin-1 light chain (KLC)-2 was predicted as one of miR-125b's targets by bioinformatics analysis. …”
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    High expression of kinesin light chain-2, a novel target of miR-125b, is associated with poor clinical outcome of elderly non-small-cell lung cancer patients
  18. 38
    “…Here we demonstrate that in Alzheimer’s disease frontal cortex, KLC1 levels are reduced and the relative levels of KLC1 serine-460 phosphorylation are increased; these changes occur relatively early in the disease process. …”
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    Kinesin light chain-1 serine-460 phosphorylation is altered in Alzheimer’s disease and regulates axonal transport and processing of the amyloid precursor protein
  19. 39
    “…Here, we show that LMTK2 regulates a known pathway that controls phosphorylation of kinesin-1 light chain-2 (KLC2) by glycogen synthase kinase-3β (GSK3β). KLC2 phosphorylation by GSK3β induces release of cargo from KLC2. …”
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    Lemur tyrosine kinase-2 signalling regulates kinesin light chain-2 phosphorylation and binding of Smad2 cargo
  20. 40
    “…We demonstrate that bristle mitochondria transport requires Khc but not Klc as a competing force to dynein heavy chain (Dhc). …”
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    Dynamic microtubule organization and mitochondrial transport are regulated by distinct Kinesin-1 pathways
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