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2101por Wen, Daxing, Xu, Haicheng, Xie, Liuyong, He, Mingrong, Hou, Hongcun, Wu, Chenglai, Li, Yan, Zhang, Chunqing“…Among these genes, the top three involved linoleate 9S-lipoxygenase (Traes_2DL_D4BCDAA76, Traes_2DL_CE85DC5C0, and Traes_2DL_B5B62EE11). Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis revealed that pathways involved in nutrient mobilization and the antioxidant system showed enhanced expression under N240. …”
Publicado 2018
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2102“…Each gene was encoded using the gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment scores. …”
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2103“…The DEGs and DEMs were then validated using data from The Cancer Genome Atlas and subjected to gene ontology and Kyoto Encyclopedia of Genes and Genomes pathway analysis. …”
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2104“…Drug resistance is a major problem in the treatment of non-small-cell lung cancer (NSCLC). In this study, Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis was performed to identify the differentially expressed genes in Adriamycin (ADR)-resistant NSCLC A549/ADR cells compared with parental A549 cells. …”
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2105por Tharehalli, Umesh, Svinarenko, Michael, Kraus, Johann M., Kühlwein, Silke D., Szekely, Robin, Kiesle, Ute, Scheffold, Annika, Barth, Thomas F.E., Kleger, Alexander, Schirmbeck, Reinhold, Kestler, Hans A., Seufferlein, Thomas, Oswald, Franz, Katz, Sarah-Fee, Lechel, André“…Deregulation of the biliary compartment and cholestasis are associated with the change of several signalling pathways including a Kyoto Encyclopedia of Genes and Genomes (KEGG) gene set representing the Hippo pathway, further yes-associated protein (YAP) activation and upregulation of SRY (sex determining region Y)-box 9 (SOX9), which is associated with transdifferentiation of hepatocytes. …”
Publicado 2018
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2106“…KEGG (Kyoto Encyclopedia of Genes and Genomes; https://www.kegg.jp/ or https://www.genome.jp/kegg/) is a reference knowledge base for biological interpretation of genome sequences and other high-throughput data. …”
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2107The study of blood transcriptome profiles in Holstein cows with miscarriage during peri-implantationpor Zhao, Guoli, Li, Yanyan, Kang, Xiaolong, Huang, Liang, Li, Peng, Zhou, Jinghang, Shi, Yuangang“…METHODS: Total transcriptomes were checked by RNA sequencing, and the analyzed by bioinformatics methods, the differentially expressed genes (DEGs) were analysed with hierarchical clustering and Kyoto encyclopedia of genes and genomes (KEGG) pathway analysis. …”
Publicado 2019
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2108por Zhang, Guojun, Sun, Zhenzhen, Zhou, Di, Xiong, Min, Wang, Xian, Yang, Junming, Wei, Zunzheng“…Totally, 634 non-redundant unigenes including 145 contigs and 489 singletons were finally identified and mainly involved in biosynthetic, metabolic processes and response to stress according to BLASTX results, gene ontology (GO) categories and Kyoto Encyclopedia of Genes and Genomes (KEGG) maps. …”
Publicado 2015
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2109“…The therapeutic implications of the proteomic findings are estimated by gene ontology enrichment analysis (GO) and the Kyoto Encyclopedia of Genes and Genomes (KEGG)-based bioinformatic analyses and further elucidated by exosome co-incubating. …”
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2110“…An up-expression in oncogenic microRNAs, which belong to broadly conserved seed families, were observed in untreated control and EGCG-treated A549 cells. Kyoto Encyclopedia of Genes and Genomes and Protein Analysis Through Evolutionary Relationships pathway analyses of the validated microRNA targeting genes strengthened the hypothesis that EGCG treatment can modulate microRNAs that play a significant role in the MAPK signaling pathway. …”
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2111“…The aim of this study was to examine whether the changes in PVAT properties could participate in progression of vascular abnormalities in developing spontaneously hypertensive rats (SHR). Normotensive Wistar-Kyoto (WKY) rats and SHR, both in 5th and in 12th week of age, were used. …”
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2112por Cheng, Liyun, Shi, Guijun, Fang, Chunxiao, Li, Guanghua, Zheng, Yong, Chen, Weigang“…The most highly enriched Kyoto Encyclopedia of Genes and Genomes pathway for the differentially-expressed miRNAs was ‘Endocrine and other factor-regulated calcium reabsorption’. …”
Publicado 2019
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2113por He, Jiafa, Deng, Li, Liu, Heping, Chen, Taiying, Chen, Shengying, Xia, Shangzhou, Liu, Yubin“…ELISA and co-immunoprecipitation suggested that the combination between BCL2L10 and Beclin 1 reduced the bond between Beclin 1 and PI3KC3. Based on Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis, the PI3K/AKT signaling pathway was significantly upregulated in HCC. …”
Publicado 2019
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2114por Yang, Liangjun, Liu, Wei, Hu, Zhipeng, Yang, Maoyi, Li, Jiali, Fan, Xiangzhen, Pan, Huafeng“…The mechanisms underlying the therapeutic effect of WPX were investigated with gene ontology (GO) enrichment analysis and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis. …”
Publicado 2019
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2115por Zhao, Bin, Baloch, Zulqarnain, Ma, Yunhan, Wan, Zheng, Huo, Yani, Li, Fujun, Zhao, Yilin“…The gene ontology functional enrichment analysis and the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis were accomplished to view the biological process, cellular components, molecular function, and the KEGG pathways of DEGs. …”
Publicado 2019
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2116por Wang, Yuan, Cong, Yuting, Wang, Yonghua, Guo, Zihu, Yue, Jinrong, Xing, Zhenyu, Gao, Xiangnan, Chai, Xiaojie“…DAPs were annotated and classified into gene ontology functional groups. The Kyoto Encyclopedia of Genes and Genomes pathway analysis linked DAPs to tricarboxylic acid cycle, photosynthesis and oxidative phosphorylation. …”
Publicado 2019
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2117por Li, Lihui, Huang, Qiangmin, Barbero, Marco, Liu, Lin, Nguyen, Thitham, Xu, Anle, Ji, Lijuan“…Hierarchical clustering, Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment and protein-protein interaction network analyses were performed for the general characterization of overall enriched proteins. …”
Publicado 2019
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2118por Zhu, Naiqiang, Hou, Jingyi, Wu, Yuanhao, Li, Geng, Liu, Jinxin, Ma, GuiYun, Chen, Bin, Song, Youxin“…Gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes pathway (KEGG) enrichment analyses were performed to identify functional categories and associated molecular and biochemical pathways, respectively, for the identified DEGs, and a protein-protein interaction (PPI) network of the DEGs was constructed using Cytoscape software. …”
Publicado 2018
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2119por Hakim, Joseph A., Schram, Julie B., Galloway, Aaron W. E., Morrow, Casey D., Crowley, Michael R., Watts, Stephen A., Bej, Asim K.“…Predicted functional profiles showed Kyoto Encyclopedia of Genes and Genomes (KEGG) Level-2 categories of energy metabolism, membrane transport, cell motility, and signal transduction in the gut tissue, and the gut digesta represented amino acid, carbohydrate, vitamin and cofactor metabolisms, and replication and repair. …”
Publicado 2019
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2120“…We found that there were a total of 7192 genes (5720 upregulated and 1472 downregulated, fold-change ≥ 2 or ≤ 0.5 for upregulation or downregulation, q-value < 0.05) differentially expressed in NaB-treated cells as compared with the untreated controls. Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway analysis demonstrated that the differentially expressed genes were enriched in DNA replication, cell cycle, homologous recombination, pyrimidine metabolism, mismatch repair, and other signaling pathways and may take part in NaB-induced cell death. …”
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