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721“…Our analysis identified 125 proteins with expression levels that were significantly upregulated or downregulated in 12-week-old spontaneously hypertensive rats compared to normotensive Wistar Kyoto rats. Using an angiogenesis enrichment analysis, we further identified a critical imbalance in angiogenic proteins that promoted an anti-angiogenic profile in cerebral arteries at early onset of hypertension. …”
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722por Khromov, Tatjana, Dihazi, Gry Helene, Brockmeyer, Phillipp, Fischer, Andreas, Streit, Frank“…Conclusion: The CLAM-2000 (Shimadzu, Kyoto, Japan) provides reproducible results as an established routine instrument and is a useful tool for 24/7 TDM of beta-lactam antibiotics in routine clinical diagnostics.…”
Publicado 2023
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723por Dai, Jing, Dong, Xiang, Chen, Yuxin, Xue, Wanying, Wang, Qingqing, Shang, Feifei, Zhao, Yunxia, Li, Shujing, Gao, Yu, Wang, Yuanyuan“…The gene ontology analysis and Kyoto Encyclopedia of Genes and Genomes functional pathway analysis were used to further predict the function of DEGs after the overexpression of SPOP. …”
Publicado 2023
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724“…METHODS: We reanalyzed differentially expressed genes in the gene expression dataset GSE114990 and predicted their target genes, followed by experimental Gene Ontology (GO) analysis and (Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis. …”
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725“…By identifying statistically significant enrichment of GO terms, Kyoto Encyclopedia of Genes and Genomes pathways, and TRANSFAC transcription factor binding sites, users can gain substantial insight into the physiological significance of sets of differentially expressed genes. …”
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726“…We describe metabolic MANET, a database that links information in the Structural Classification of Proteins (SCOP), the Kyoto Encyclopedia of Genes and Genomes (KEGG), and phylogenetic reconstructions depicting the evolution of protein fold architecture. …”
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727“…The meeting set the tone for next the Annual meeting in Kyoto, Japan for the year 2008 with the theme "Tobacco free future".…”
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728“…Motivation: KEGG PATHWAY is a service of Kyoto Encyclopedia of Genes and Genomes (KEGG), constructing manually curated pathway maps that represent current knowledge on biological networks in graph models. …”
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729Can the envisaged reductions of fossil fuel CO(2) emissions be detected by atmospheric observations?“…This perspective constitutes the urgently needed tool for validation of fossil fuel CO(2) emissions changes in the framework of the Kyoto protocol and successive climate initiatives.…”
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730por Yamagata, Kazuo, Kitazawa, Takuya, Shinoda, Masahiro, Tagawa, Chika, Chino, Makoto, Matsufuji, Hiroshi“…We examined the possibility that the expression of adhesion molecules is regulated differently in cultured astrocytes from stroke-prone spontaneously hypertensive rats (SHRSP/IZM) rats than in those from Wistar Kyoto rats (WKY/IZM) by tumor necrosis factor-alpha (TNF-α) or hypoxia and reoxygenation (H/R) and the inhibitory effects of apigenin. …”
Publicado 2009
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731por Zhu, Qiang, Qin, Tao, Jiang, Ying-Ying, Ji, Cong, Kong, De-Xin, Ma, Bin-Guang, Zhang, Hong-Yu“…In this paper, chemoinformatic analyses on metabolic networks of Kyoto Encyclopedia of Genes and Genomes (KEGG), Escherichia coli and Saccharomyces cerevisiae were performed. …”
Publicado 2011
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732“…The increasing trends and large interannual variations in soil GHG fluxes seem to substantially affect Japan's Kyoto accounting and future GHG mitigation strategies.…”
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733“…Two gordiid worms were collected in the vomit and excreta of an 80-year-old woman in November 2009 in Kyoto city, and in the mouth of 1-year-old boy in December 2009 in Nara city, Japan, respectively. …”
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734por Almon, Richard R., DuBois, Debra C., Sukumaran, Siddharth, Wang, Xi, Xue, Bai, Nie, Jing, Jusko, William J.“…In this report, we characterized the response of Goto-Kakizaki (GK) rats, a spontaneous polygenic model for lean diabetes and healthy Wistar-Kyoto (WKY) controls, to high fat feeding from weaning to 20 weeks of age. …”
Publicado 2012
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735“…Furthermore, gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes(KEGG) pathway analysis revealed enrichment of biological processes associated with energy metabolism and signal transduction events, including the peroxisome proliferator-activated receptor gamma (PPARγ) signaling pathway, and mitogen-activated protein kinases(MAPK) and Ras homolog gene family, member A (RhoA) signaling. …”
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736por Crasto, Chiquito, Narne, Chandrahas, Kawai, Mikako, Wilson, Landon, Barnes, Stephen“…MRMPath utilizes publicly available information related to biological pathways in the Kyoto Encyclopedia of Genes and Genomes (KEGG) database. …”
Publicado 2013
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737por Moisá, Sonia J., Shike, Daniel W., Graugnard, Daniel E., Rodriguez-Zas, Sandra L., Everts, Robin E., Lewin, Harris A., Faulkner, Dan B., Berger, Larry L., Loor, Juan J.“…Bioinformatic analysis was performed using the dynamic impact approach (DIA) by means of Kyoto Encyclopedia of Genes and Genomes (KEGG) and Database for Annotation, Visualization and Integrated Discovery (DAVID) databases. …”
Publicado 2013
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738por Sontag, Thomas-A., Fuermaier, Anselm B. M., Hauser, Joachim, Kaunzinger, Ivo, Tucha, Oliver, Lange, Klaus W.“…In comparison to Wistar-Kyoto (WKY) rats, SHRs did not have any impairment in spatial working memory and reference memory. …”
Publicado 2013
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739por Wang, Panwen, Lai, Wing-Fu, Li, Mulin Jun, Xu, Feng, Yalamanchili, Hari Krishna, Lovell-Badge, Robin, Wang, Junwen“…By applying our method to two human representative diseases, Type 2 Diabetes and Breast Cancer, we demonstrated that our method is able to identify related Gene Ontology terms and Kyoto Encyclopedia of Genes and Genomes pathways. …”
Publicado 2013
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740por Guo, Min, Zhou, Qian, Zhou, Yizhuang, Yang, Linfeng, Liu, Tianxiang, Yang, Jinlong, Chen, Yanling, Su, Longxiang, Xu, Jin, Chen, Jing, Liu, Feng, Chen, Jiapeng, Dai, Wenkui, Ni, Peixiang, Fang, Chengxiang, Yang, Ruifu“…Moreover, we predicted and reconstructed their core/pan metabolic pathways using the KEGG (Kyoto Encyclopedia of Genes and Genomes) orthology system. …”
Publicado 2014
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