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761“…RNA-seq profiling indicated that 1,854 lncRNAs were differentially expressed (log2 fold change ≥ 1 or ≤−1, p < 0.05), in which 1,530 could potentially target 6,386 genes via cis-regulatory effects. Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis for these target genes suggested that lncRNAs were involved in diverse pathways, such as lysosome, focal adhesion, and MAPK signaling. …”
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762por Xing, Dongxu, Yang, Qiong, Jiang, Liang, Li, Qingrong, Xiao, Yang, Ye, Mingqiang, Xia, Qingyou“…DEGs and the enriched Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways of the two strains exhibited an obvious difference. …”
Publicado 2017
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763“…We mapped 4,329 unigenes onto 317 pathways using the Kyoto Encyclopedia of Genes and Genomes Pathway database. …”
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764“…In the present report, we examined the responses of diabetic Goto-Kakizaki (GK) rats and control Wistar-Kyoto (WKY) rats fed either a standard chow or high-fat diet (HFD) from weaning to 20 weeks of age. …”
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765“…Many of the significant Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways, including these differentially expressed proteins, were closely related to muscle growth, including apoptosis, thyroid hormone signaling, regulation of the actin cytoskeleton, and viral myocarditis (p < 0.05). …”
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766“…Pathways were obtained from the database of Kyoto Encyclopedia of Genes and Genomes and Retrieval of Interacting Genes was used to download protein-protein interaction sets. …”
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767“…In addition, a pathway analysis showed that these DEGs were significantly enriched in 33 Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways, including cell adhesion molecules, ECM-receptor interaction, and cytokine-cytokine receptor interaction. …”
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768“…The 30th summer school of the Research Community for Mechanisms of Mutations was held on September 2nd-3rd, 2017 at the Kyoto Prefecture Seminar House. The Community celebrated the 30th anniversary of the school this year. …”
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769por He, Wen, Wang, Yan, Chen, Qing, Sun, Bo, Tang, Hao-Ru, Pan, Dong-Ming, Wang, Xiao-Rong“…A total of 1950 significant differentially-expressed genes (DEGs) were identified and analyzed. The Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis revealed that genes involved in carbohydrate metabolism, energy metabolism, amino acid metabolism, and plant hormone signal transduction were significantly enriched. …”
Publicado 2018
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770por Ikarashi, Nobutomo, Toda, Takahiro, Hatakeyama, Yusuke, Kusunoki, Yoshiki, Kon, Risako, Mizukami, Nanaho, Kaneko, Miho, Ogawa, Sosuke, Sugiyama, Kiyoshi“…Spontaneously hypertensive rats (SHR) with hypertension and control Wistar Kyoto rats (WKY) were used. WKY and SHR were fed AP-containing food or AP-free food (control group) ad libitum for 4 weeks, and their blood pressures were measured. …”
Publicado 2018
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771por Chuard, Nicolas, Poblador-Bahamonde, Amalia I., Zong, Lili, Bartolami, Eline, Hildebrandt, Jana, Weigand, Wolfgang, Sakai, Naomi, Matile, Stefan“…This 1,2-diselenolane delivers fluorophores efficiently to the cytosol of HeLa Kyoto cells, without detectable endosomal capture as with 1,2-dithiolanes or dominant escape into the nucleus as with epidithiodiketopiperazines. …”
Publicado 2018
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772por Won, Harim I., Schulze, Thomas T., Clement, Emalie J., Watson, Gabrielle F., Watson, Sean M., Warner, Rosalie C., Ramler, Elizabeth A. M., Witte, Elias J., Schoenbeck, Mark A., Rauter, Claudia M., Davis, Paul H.“…Validation of the assembly was performed by functional characterization using Gene Ontology (GO), Eukaryotic Orthologous Groups (KOG), and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses. …”
Publicado 2018
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773“…Therefore, the effects of AGPS silencing and knockout on circRNA expression in the thyroid cancer cell line FRO were investigated using circRNAs microarray, and Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analyses were performed in order to investigate the underlying molecular mechanism of AGPS for the regulation of thyroid cancer through circRNAs.…”
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774“…RESULTS: This approach successfully helped to identify 12 active ingredients of CN, interacting with 13 key targets (Akt1, STAT3, TNFsf13, TP53, EPHB2, IL-10, IL-6, TNF, MAPK8, IL-8, RELA, ROS1 and STAT4). Kyoto Encyclopedia of Genes and Genomes pathway enrichment analysis indicated that CN-regulated pathways were mainly classified into signal transduction and immune system. …”
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775por Muraoka, Yuki, Iida, Yuto, Ikeda, Hanako O., Iwai, Sachiko, Hata, Masayuki, Iwata, Takeshi, Nakayama, Mao, Shimozawa, Nobuhiro, Katakai, Yuko, Kakizuka, Akira, Yoshimura, Nagahisa, Tsujikawa, Akitaka“…We have created small chemicals (Kyoto University Substances; KUSs) that act as ATP regulators inside cells. …”
Publicado 2018
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776“…Based on the Gene Ontology and Kyoto Encyclopedia of Genes and Genomes databases, functional and pathway enrichment analysis were processed and a pathway relation network was constructed. …”
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777“…However, international policies like the United Nations Framework Convention on Climate Change and Kyoto Protocol do not address the matter under deliberation. …”
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778“…To facilitate further research, we used label-free quantitation method to analyze the associated differences in Kyoto Encyclopaedia of Genes and Genomes (KEGG) pathways and biological processes. …”
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779“…The function and pathway enrichment of these genes were analysed through Gene Ontology and Kyoto Encyclopedia of Genes and Genomes analyses. …”
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780“…Therefore the extracellular region, extracellular matrix, and collagen trimer might be involved in glucocorticoid-induced osteoporosis. Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis revealed that the focal adhesion signaling pathway is the most enriched signaling pathway in terms of differentially expressed genes (DEGs). …”
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