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8501“…Further, RNA sequencing detected 1,192 differentially expressed genes (DEGs) in CCE-treated fibroblasts, among which 417 were upregulated and 775 were downregulated. Kyoto Encyclopedia of Genes (KEGG) and Genomes pathway (GO) analysis based on RNA sequencing revealed that CCE mainly affected cytokine-cytokine receptor interaction regulated by HA synthesis-related genes. …”
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8502por Tao, Dan, Tan, Jueling, Zhang, Ningning, Yang, Dingyi, Jiang, Yong, Zhou, Wei, Wang, Ying, Wu, Yongzhong“…The Database for Annotation, Visualization, and Integrated Discovery (DAVID) was used to perform the enrichment of the Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways. …”
Publicado 2023
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8503“…Protein interactions and functions were predicted using Cytoscape-generated networks and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment, while the proportions of 22 immune cell types were examined with CIBERSORT. …”
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8504por Yao, Weijie, Yao, Yanrong, He, Wen, Zhao, Chengsi, Liu, Di, Wang, Genwang, Wang, Zuozheng“…After silencing PABPC1, messenger RNA sequencing and Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses were performed. …”
Publicado 2023
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8505por Xu, Yaozheng, Huo, Jiawen, Nie, Ruili, Ge, Lili, Xie, Chonghong, Meng, Yuan, Liu, Jianhua, Wu, Lina, Qin, Xiaosong“…A total of 113 potential VVA-binding glycoproteins were identified by mass spectrometry and classified by gene ontology (GO) and Kyoto encyclopedia of genes and genomes (KEGG) analyses. …”
Publicado 2023
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8506por Zhang, Shan, Liu, Jian, Shi, Lian, Wang, Qianchao, Zhang, Ping, Wang, Hongxin, Liu, Junna, Li, Hanxue, Li, Li, Li, Xinyi, Huang, Liubin, Qin, Peng“…Gene ontology and assessments of the Kyoto Encyclopedia of Genes and Genomes have uncovered important biological processes and metabolic pathways that are involved in the phosphorus level response. …”
Publicado 2023
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8507“…Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses were performed on the shared genes. …”
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8508“…In addition, differential analysis, transcription factor (TF) enrichment analysis, Gene ontology (GO) analysis and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses, and target gene prediction were used to identify specifically expressed miRNAs and their potential mechanisms of action. …”
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8509por Wang, Zhen, Zou, Jing, Zhang, Le, Liu, Hongru, Jiang, Bei, Liang, Yi, Zhang, Yuzhe“…Differentially expressed genes (DEGs) in CRPC were identified for further analyses, including Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG), and gene set enrichment analysis (GSEA). …”
Publicado 2023
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8510por Chen, Yusi, Tang, Yi, Hou, Sitong, Luo, Jun, Chen, Jingyuan, Qiu, Haihua, Chen, Wenjie, Li, Kexing, He, Jin, Li, Jiang“…It is disclosed that potential target genes of verified tsRNAs are widely involved in PAH pathways by Kyoto Encyclopedia of Genes and Genomes. Conclusion: This study investigated tsRNA profiles in idiopathic PAH and found that the dysregulated tsRNAs may become a novel type of biomarkers and possible targets for PAH.…”
Publicado 2023
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8511por Zhou, JiangFei, Huang, Jian, Li, ZhiWu, Song, QiHe, Yang, ZhenYu, Wang, Lu, Meng, QingQi“…METHODS: Normal and OA synovial gene expression profile microarrays were obtained from the Gene Expression Omnibus (GEO) database and aging-related genes (ARGs) from the Human Aging Genomic Resources database (HAGR). Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG), Disease Ontology (DO), and Gene set variation analysis (GSVA) enrichment analysis were used to uncover the underlying mechanisms. …”
Publicado 2023
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8512por Jiang, Yuting, Yang, Xiao, Li, Linlin, Lv, Xin, Wang, Ruixue, Zhang, Hongguo, Liu, Ruizhi“…In addition, functional enrichment analysis including the Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) was performed. …”
Publicado 2023
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8513por Wang, Ruye, Zhao, Ying, Miao, Chenyun, Chen, Yun, Ren, Ning, Yang, Liuqin, Cheng, Wei, Zhang, Qin, Fang, Xiaohong“…The primary targets and pathways of YLF to reduce DOR were predicted using studies of functional enrichment from the Kyoto Encyclopedia of Genes and Genomes (KEGG), Gene Ontology (GO), and Protein-Protein Interaction (PPI) networks. …”
Publicado 2023
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8514por Yang, Youzhualamu, Peng, Wei, Su, Xiaolong, Yue, Binglin, Shu, Shi, Wang, Jikun, Fu, Changqi, Zhong, Jincheng, Wang, Hui“…Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses were performed in order to identify the functional annotation of common genes. …”
Publicado 2023
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8515por Tang, Tao, He, Zhongyuan, Zhu, Zhengya, Wang, Fuan, Chen, Hongkun, Zhang, Fu, Zhou, Jiaxiang, Wang, Jianmin, Li, Baoliang, Liu, Xizhe, Zhou, Zhiyu, Liu, Shaoyu“…The potentially involved lncRNA/circRNA–miRNA–mRNA networks and protein-protein interaction networks were constructed by miRNet, circBank, STRING, and the Cytoscape database. Gene ontology, Kyoto Encyclopaedia of Genes and Genomes Analysis, Gene Set Enrichment Analysis, Gene Set Variation Analysis, Immune Infiltration Analysis, and Drug-Gene Interaction were used to analyse the top 20 hub genes. …”
Publicado 2023
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8516por He, Tianwen, Muhetaer, Muheremu, Wu, Jiahe, Wan, Jingjing, Hu, Yushuang, Zhang, Tong, Wang, Yunxiang, Wang, Qiongxin, Cai, Huanhuan, Lu, Zhibing“…Gene ontology annotation, Kyoto Encyclopedia of Genes and Genomes pathway enrichment analysis and weighted gene co-expression network analysis were performed on the common significantly differentially expressed genes (DEGs) of these three data sets, and the most relevant module genes for CAD obtained. …”
Publicado 2023
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8517por Zhang, Qi, Feng, Xiao, Zhang, Mingming, Sun, Wenjing, Zhai, Yuqing, Qing, Shuangshuang, Liu, Ying, Zhao, Haoran, Sun, Jing, Zhang, Yi, Ma, Chaoqun“…Clinical samples were obtained from the TCGA (The Cancer Genome Atlas) databases. Gene ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG), GSVA, and the MAlignant Tumors using Expression data (ESTIMATE) algorithm were employed to research the potential mechanism and pathways. …”
Publicado 2023
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8518“…Gene Ontology (GO) functional annotation, Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway functional enrichment, and protein–protein interaction analyses of DEPs were conducted to identify their relevant biological processes, cellular components, and related pathways. …”
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8519“…We combined the GEO with the GeneCards database and performed Gene Ontology and Kyoto Encyclopedia of Genes and Genome analyses; then, the least absolute shrinkage and selection operator (LASSO) algorithm was used to identify the characteristic genes, and a predictive risk score was established. …”
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8520“…The results of Gene Ontology analysis suggested a significant enrichment of DEGs in ‘organic anion transport’ and ‘small molecule catabolic process’ in biological processes, in ‘apical plasma membrane’ and ‘apical part of the cell’ in cell components, and in ‘anion transmembrane transporter activity’ and ‘active transmembrane transporter activity’ in molecular functions. Kyoto Encyclopedia of Genes and Genomes pathway enrichment analysis indicated that the DEGs were significantly enriched in the ‘phagosome’, the ‘PPAR signaling pathway’, ‘complement and coagulation cascades’, the ‘HIF-1 signaling pathway’ and ‘carbon metabolism’. …”
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