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9281por Nguyen, Thong Ba, Do, Duy Ngoc, Nguyen-Thanh, Tung, Tatipamula, Vinay Bharadwaj, Nguyen, Ha Thi“…Based on the results of protein–protein interaction, gene co-expression network, and survival analyses, DNA topoisomerase II alpha (TOP2A), ribonucleotide reductase regulatory subunit M2 (RRM2), never in mitosis-related kinase 2 (NEK2), cyclin-dependent kinase 1 (CDK1), and cyclin B1 (CCNB1) were identified as the hub genes. Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analyses showed that the differentially expressed genes (DEGs) were enriched in the immune-associated pathways. …”
Publicado 2021
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9282“…The serum levels of Ang II and expression of AT1R in the muscle were higher in SHRs than in normotensive animals of Wistar–Kyoto rats (2.4 and 1.8 times higher than WKY, respectively). …”
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9283por Hou, Xuemei, Qi, Nana, Wang, Chunlei, Li, Changxia, Huang, Dengjing, Li, Yihua, Wang, Ni, Liao, Weibiao“…The sucrose and starch metabolism, cysteine and methionine metabolism and phenylalanine metabolism were significantly enriched in the analysis of the Kyoto encyclopedia of genes and genomes (KEGG). In addition, the genes involved in carbohydrate metabolism were significantly upregulated or downregulated (upregulated 22 DEGs, downregulated 15 DEGs), indicating that starch and sucrose metabolism held a central position. …”
Publicado 2021
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9284por Zhao, Yuanyuan, Tao, Jiahao, Chen, Zhuangzhong, Li, Suihui, Liu, Zeyu, Lin, Lizhu, Zhai, Linzhu“…The protein–protein interaction (PPI) network of curcumin-mediated proteins was visualized using Cytoscape. Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis was performed for all curcumin-mediated proteins. …”
Publicado 2021
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9285“…To identify the molecular role of RASGRF2 in STAD, gene ontology (GO) term, Kyoto Encyclopedia of Genes and Genomes (KEGG) biological pathway, and gene set enrichment analysis (GSEA)-mediated functional module enrichment analyses were conducted. …”
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9286por Lu, Yanjiao, Chen, Jinkun, Wang, Shanshan, Tian, Zhen, Fan, Yan, Wang, Meijia, Zhao, Jianping, Tang, Kun, Xie, Jungang“…The differently expressed genes (DEGs) were systemically analyzed using Gene Ontology (GO) functional, Kyoto Encyclopedia of Genes and Genomes (KEGG), and hub genes analysis. …”
Publicado 2021
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9287por Zhang, PeiPei, Ma, KeXin, Ke, XiaoFei, Liu, Liu, Li, Ying, Liu, YaJuan, Wang, YouJun“…Functional enrichment analysis was performed using the Kyoto Encyclopedia of Genes and Genomes and gene ontology databases. …”
Publicado 2021
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9288“…IGFBP3/5/6/7 were associated with clinical cancer stage. Gene ontology and Kyoto Encyclopedia of Genes and Genome analyses showed that IGFBP3/5/7 were mainly enriched in focal adhesion, extracellular matrix structural constituent, cell-substratist junction, extracellular structure, and matrix organization. …”
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9289por Luo, Shu, Wang, Lina, Li, Shuming, Wang, Hongwei, Huang, Sujing, Zhang, Zhongxia, Wang, Ru, Guan, Hongqiong, Huang, Yuanhua“…In addition, we performed Geno ontology (GO) and Kyoto encyclopedia of genes and genomes (KEGG) on DEGs and DELs-target genes to explore their function. …”
Publicado 2021
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9290por Huang, Shan-Shan, Guo, Dong-Yang, Jia, Bing-Bing, Cai, Guo-Long, Yan, Jing, Lu, Yan, Yang, Zhou-Xin“…In addition, Gene Ontology (GO) enrichment analysis showed that differential genes were associated with transcript levels and DNA replication. Kyoto encyclopedia of genes and genomes (KEGG) enrichment showed that signaling pathways, such as tumor necrosis factor (TNF), Jak, Toll-like receptor and IL-17, were altered after DI treatment. …”
Publicado 2021
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9291por Xu, Jia, Zhang, Ming-Ying, Jiao, Wei, Hu, Cong-Qi, Wu, Dan-Bin, Yu, Jia-Hui, Chen, Guang-Xing“…Functional annotation of DEGs was performed, including Gene Ontology (GO) analysis and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis. …”
Publicado 2021
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9292“…The intersection of the DEPs in both the TYP group and IGT model group underwent Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses to identify the related biological functions and signal transduction pathways. …”
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9293por Tang, Lili, Chen, Ping, Yang, Liu, Liu, Jiyuan, Zheng, Yuanfang, Lin, Jincai, Chen, Senhua, Luo, Yinzhu, Chen, Yanyan, Ma, Xiaoying, Zhang, Liyan“…Differential enrichment peaks (DEPs) and regions of interest (ROIs) were identified, based on which Gene Ontology (GO) enrichment, Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway, and reactome pathway enrichments were analyzed. …”
Publicado 2021
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9294por Liu, Xiaoming, Zou, Yao, Zhang, Yingchi, Liu, Lipeng, Duan, Yongjuan, Zhang, Aoli, Zhang, Xiaoyan, Zhang, Ranran, Zhao, Beibei, Li, Xiaolan, Wei, Tong, He, Hongrui, Gan, Yu, Wang, Kejian, Zhu, Xiaofan“…A receiver operating characteristic (ROC) curve yielded the area under the curve (AUC) of 0.773 for classification between the two groups. In addition, the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways involved in the bacterial secretion system were more enriched in the affected group than in the control group. …”
Publicado 2021
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9295por Li, Jiansheng, Zhao, Peng, Tian, Yange, Li, Kangchen, Zhang, Lanxi, Guan, Qingzhou, Mei, Xiaofeng, Qin, Yanqin“…ECC targets and COPD genes and targets were identified from multiple databases, and then used for an analysis of protein–protein interaction (PPI) networks, Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways, and biological functioning. …”
Publicado 2021
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9296por Pu, Wenyuan, Zhao, Chen, Wazir, Junaid, Su, Zhonglan, Niu, Mengyuan, Song, Shiyu, Wei, Lulu, Li, Li, Zhang, Xia, Shi, Xudong, Wang, Hongwei“…To assess the transcriptional differences between the expressed genes, the bioinformatics analysis was performed using a standard pipeline of quality control, reference mapping, differential expression analysis, protein‐protein interaction (PPI) networks, gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis. …”
Publicado 2021
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9297“…Gene Ontology (GO) function and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis for DEGs were performed using the DAVID to present the most visibly enriched pathways. …”
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9298por Jin, Meiling, Ren, Wenwen, Zhang, Weiguang, Liu, Linchang, Yin, Zhiwei, Li, Diangeng“…Then, the clusterProfiler package of R was used for Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis. …”
Publicado 2021
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9299“…Besides, with the coexpression analysis, Gene Ontology (GO), Gene Set Enrichment Analysis (GSEA), and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis, the molecular pathomechanisms that were mediated by FAM57A in HCC were elucidated. …”
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9300“…Univariate and multivariate Cox regression analyses were employed to identify the prognostic circadian genes. Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG) and Gene Set Enrichment Analysis (GSEA) were performed to study the biological functions of ARNTL2. …”
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