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10421“…Subsequently, Gene Ontology (GO) and Kyoto encyclopedia of genes and genomes (KEGG) pathway enrichment analyses, Gene set enrichment analysis (GSEA), Gene set variation analysis (GSVA), competitive endogenous RNA (ceRNA) (lncRNA-miRNA-mRNA) network, protein–protein interaction (PPI) network, and gene transcription factors (TFs) network analyses were performed to identify hub genes and associated pathways. …”
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10422“…The overlapping targets of DHJSD and AS were identified, and then Gene Ontology functional enrichment and Kyoto Encyclopedia of Genes and Genomes enrichment analyses were performed. …”
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10423por Zeng, Taofei, Chen, Guanglei, Qiao, Xinbo, Chen, Hui, Sun, Lisha, Ma, Qingtian, Li, Na, Wang, Junqi, Dai, Chaoliu, Xu, Feng“…Subsequently, Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways enrichment analysis, protein-protein interaction (PPI) network were integrated to explore the potential function of the DEGs and hub genes. …”
Publicado 2022
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10424“…Functional enrichment of differentially expressed genes was explored using Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway analyses. …”
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10425por Tian, Minghui, Gao, Hua, Jiao, Hongfei, Tian, Hongbin, Han, Lulu, Lin, Xiaowan, Cheng, Gong, Sun, Fenglei, Feng, Bo“…The gene annotation and analysis were performed with the Metascape database via functional databases, such as the Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG), and Autodock and PyMOL were used for the molecular docking. …”
Publicado 2022
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10426“…Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis was performed on the differential genes. …”
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10427por Li, Qing, Liu, Yuntao, Yang, Min, Jin, Lianshun, Wu, Yali, Tang, Lijuan, He, Liuyun, Wu, Dinghong, Zhang, Zhongde“…Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) were applied for the above genes. …”
Publicado 2022
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10428por Li, Yongang, Gu, Jiachen, Mao, Youbing, Wang, Xijia, Li, Zongshan, Xu, Xiaomin, Chen, Huimin, Gui, Yaxing“…Eight miRNAs were found to be lower expressed in anti-NMDAR encephalitis CSF-derived exosomes. Furthermore, Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways enriched by AE differential expressed exosomic miRNAs demonstrated that AE-related exosomic miRNAs may participate as a feedback regulation in cancer development. …”
Publicado 2022
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10429por Ghignatti, Paola Victória da Costa, Russo, Mariana Kras Borges, Becker, Tiago, Guecheva, Temenouga Nikolova, Teixeira, Luciele Varaschini, Lehnen, Alexandre Machado, Schaun, Maximiliano Isoppo, Leguisamo, Natalia Motta“…To evaluate the effect of preventive aerobic exercise training on sympathovagal function, cardiac function, and DNA repair capacity in a preclinical model of doxorubicin (DOX)-induced cardiomyopathy. Forty male Wistar-Kyoto rats were allocated into four groups (n = 10/group): D (DOX-treated) and C (controls) remained sedentary, and DT (DOX-trained) and CT (control-trained) performed aerobic training 4 days/week, during 4 weeks before exposure to DOX (4 mg/kg/week during 4 weeks) or saline solution. …”
Publicado 2022
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10430por Wu, Yanze, Jiang, Ting, Hua, Jinghai, Xiong, Zhiping, Chen, Hui, Li, Lei, Peng, Jingtian, Xiong, Wenjun“…Furthermore, DEGs were performed via gene ontology (GO) functional and kyoto encyclopedia of genes and genome (KEGG) pathway analyses. …”
Publicado 2022
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10431por Yang, Kun, Wang, Fengyan, Li, Ke, Peng, Guoxuan, Yang, Hua, Xu, Hong, Xiang, Yang, Sun, Hong“…Gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses were performed to analyze the function of genes involved in the ceRNA network. …”
Publicado 2022
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10432“…Gene Ontology (GO) functional term and Kyoto Encyclopedia of Genes and Genomes (KEGG) signaling pathway enrichment analyses were also performed. …”
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10433por Zhang, Lingyu, Guo, Qiuping, Duan, Yehui, Lin, Xue, Ni, Hengjia, Zhou, Chuanshe, Li, Fengna“…Meanwhile, the protein expression levels of the mammalian target of rapamycin pathways were up-regulated after treatment with 25 μM ZnMet (P < 0.05), which is consistent with the results of the enriched Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway in the transcriptome analysis. …”
Publicado 2022
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10434por Gao, Yahui, Feng, Jing, Wu, Jiafa, Wang, Kun, Wu, Shuang, Liu, Hongcun, Jiang, Mingguo“…The downregulated genes were involved in six biological processes, namely cell redox homeostasis, cellular homeostasis, carbohydrate metabolic process, homeostatic process, obsolete electron transport, and regulation of biological quality. Kyoto encyclopedia of genes and genomes (KEGG) pathway analysis showed that 190 upregulated differentially expressed genes were mainly involved in plant hormone signal transduction, phenylpropyl biosynthesis, plant–pathogen interaction, and flavonoid biosynthesis. …”
Publicado 2022
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10435por Qian, Dongdong, Tian, Jing, Wang, Sining, Shan, Xiaoli, Zhao, Pei, Chen, Huihua, Xu, Ming, Guo, Wei, Zhang, Chen, Lu, Rong“…In neonatal rat cardiomyocytes (NRCMs), RNA sequencing and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis were carried out to identify potential pathways of TCA. …”
Publicado 2022
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10436por Han, Miao, Li, Heng, Ke, Dan, Tian, Li-Ming, Hong, Yi, Zhang, Chong, Tian, Dai-Zhi, Chen, Long, Zhan, Li-Rui, Zong, Shi-Qin“…Finally, we performed Gene Ontology (GO) enrichment analysis and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis by Metascape database. …”
Publicado 2022
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10437por Wang, Wen, Liu, Xiaojing, Wei, Peiyao, Ye, Feng, Chen, Yunru, Shi, Lei, Zhang, Xi, Li, Jianzhou, Lin, Shumei, Yang, Xueliang“…“Lipid metabolism,” “inflammatory response,” and “lymphocyte activation” were the most significant biological functions in GSE48452, GSE58979, and GSE151158, respectively. Kyoto Encyclopedia of Genes and Genomes pathway analysis showed that the toll-like receptor signaling pathway was significantly enriched in NASH patients. …”
Publicado 2022
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10438por Yamamoto, Erika, Kato, Takao, Yaku, Hidenori, Morimoto, Takeshi, Inuzuka, Yasutaka, Tamaki, Yodo, Ozasa, Neiko, Yoshikawa, Yusuke, Kitai, Takeshi, Taniguchi, Ryoji, Iguchi, Moritake, Kato, Masashi, Takahashi, Mamoru, Jinnai, Toshikazu, Ikeda, Tomoyuki, Nagao, Kazuya, Kawai, Takafumi, Komasa, Akihiro, Nishikawa, Ryusuke, Kawase, Yuichi, Morinaga, Takashi, Kawato, Mitsunori, Seko, Yuta, Shiba, Masayuki, Toyofuku, Mamoru, Furukawa, Yutaka, Nakagawa, Yoshihisa, Ando, Kenji, Kadota, Kazushige, Shizuta, Satoshi, Ono, Koh, Sato, Yukihito, Kuwahara, Koichiro, Kimura, Takeshi“…However, the association between appetite loss at discharge and long-term outcome remains unclear. METHODS: The Kyoto Congestive Heart Failure registry is a prospective cohort study that enrolled consecutive patients hospitalized for acute decompensated heart failure (ADHF) in Japan. …”
Publicado 2022
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10439por Yao, Ninghua, Zuo, Ling, Yan, Xiaodi, Qian, Jing, Sun, Jie, Xu, Huawei, Zheng, Feifei, Efird, Jimmy T., Kawagoe, Izumi, Wang, Yan, Ni, Sujie“…The biological functions of the characterized lncRNAs were analyzed by Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG). We evaluated the prognostic power of this model using Kaplan-Meier analysis, receiver operating characteristic (ROC), and decision curve analysis (DCA). …”
Publicado 2022
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10440por Liu, Chuan, Wang, Ting, Yang, Jiahui, Zhang, Jixiang, Wei, Shuchun, Guo, Yingyun, Yu, Rong, Tan, Zongbiao, Wang, Shuo, Dong, Weiguo“…The gene chip GSE41258 was downloaded from the GEO database, and differentially expressed genes (DEGs) were screened by the GEO2R online tool (p < 0.05, |logFC|>1.5). The Kyoto Encyclopedia of Genes and Genomes (KEGG) Pathway and Gene Ontology (GO) annotation and String website were used for enrichment analysis and protein–protein interaction (PPI) analysis of DEGs, respectively, and Cytoscape software was used to construct PPI network and screen function modules and hub genes. …”
Publicado 2022
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