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10921por Domingues, William B., Silveira, Tony L. R., Nunes, Leandro S., Blodorn, Eduardo B., Schneider, Augusto, Corcine, Carine D., Varela Junior, Antônio S., Acosta, Izani B., Kütter, Mateus T., Greif, Gonzalo, Robello, Carlos, Pinhal, Danillo, Marins, Luís F., Campos, Vinicius F.“…In this study, an average of 134 differentially expressed miRNAs-targeted genes were predicted using the in silico approach. Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis demonstrated that the genes of affected pathways were primarily related to spermatogenesis, sperm motility, and cell apoptosis. …”
Publicado 2021
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10922“…Then, the gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses were performed to explore the biological functions and signaling pathways. …”
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10923por Ge, Yanzhi, Chen, Zuxiang, Fu, Yanbin, Xiao, Xiujuan, Xu, Haipeng, Shan, Letian, Tong, Peijian, Zhou, Li“…The Gene Ontology (GO) functional annotation, Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways and protein–protein interaction (PPI) network analysis of DEGs were conducted to determine hub genes and pathways. …”
Publicado 2021
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10924“…Gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) were performed for pathway analysis based on the selected genes with significant differences in expression. …”
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10925por Luo, Jieyan, Hu, Qipeng, Gou, Maling, Liu, Xiaoke, Qin, Yi, Zhu, Jiao, Cai, Chengzhi, Tian, Tian, Tu, Zegui, Du, Yijia, Deng, Hongxin“…Meanwhile, we performed Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis on the expression data of MAPs and their 50 frequently altered neighbor genes in NSCLC tissues. …”
Publicado 2021
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10926“…In addition, the biological functions of genes in the ceRNA network were also annotated by Gene Ontology and Kyoto Encyclopedia of Genes and Genomes. Our study promotes exploration of the molecular mechanisms associated with tumorigenesis and provide potential targets for GBC diagnosis and treatment. …”
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10927“…METHODS: The transcriptome data of colon cancer and clinical characteristics were downloaded from The Cancer Genome Atlas (TCGA) database. Gene ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis, and Gene Set Enrichment Analysis (GSEA) were performed to elucidate the gene functions and relative pathways. …”
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10928por Heinrich, Maria, Sieg, Miriam, Kruppa, Jochen, Nürnberg, Peter, Schreier, Peter H., Heilmann-Heimbach, Stefanie, Hoffmann, Per, Nöthen, Markus M., Janke, Jürgen, Pischon, Tobias, Slooter, Arjen J. C., Winterer, Georg, Spies, Claudia D.“…We aim to investigate the association between genetic variants in cholinergic candidate genes according to the Kyoto encyclopedia of genes and genomes - pathway: cholinergic neurotransmission with the development of POD or POCD in elderly patients. …”
Publicado 2021
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10929por Olech, Monika, Ropka-Molik, Katarzyna, Szmatoła, Tomasz, Piórkowska, Katarzyna, Kuźmak, Jacek“…DEGs detected between LPL and HPL groups were found to have significantly enriched regulation of signaling receptor activity, the response to toxic substances, nicotinamide adenine dinucleotide (NADH) dehydrogenase complex assembly, cytokine production, vesicle, and vacuole organization. In turn, the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway tool classified DEGs that enrich molecular processes such as B and T-cell receptor signaling pathways, natural killer cell-mediated cytotoxicity, Fc gamma R-mediated phagocytosis, toll-like receptor signaling pathways, TNF, mammalian target of rapamycin (mTOR) signaling and forkhead box O (Foxo) signaling pathways, etc. …”
Publicado 2021
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10930por Zhang, Mi, Zhao, Wei, Liu, Shanshan, Liu, Haichuan, Liu, Liang, Peng, Qiling, Du, Chengyou, Jiang, Ning“…Survival analysis, Gene Ontology (GO), and Kyoto Encyclopedia of Genes and Genomes enrichment pathway (KEGG) analyses were performed using R software. …”
Publicado 2021
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10931por Wang, Mingqiang, Yang, Dan, Hu, Zhao, Shi, Yunke, Ma, Yiming, Cao, Xingyu, Guo, Tao, Cai, Hongbo, Cai, Hongyan“…Nitric oxide (NO) levels were measured using an NO assay kit. Results: Kyoto encyclopedia of genes and genomes (KEGG) enrichment analysis showed that differentially expressed genes were enriched in cancer signaling, PI3K-Akt signaling, and Rap1 signaling pathways. …”
Publicado 2021
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10932por Li, Yanxin, Ma, Ke, Xie, Qi, Zhang, Xianwei, Zhang, Xiulei, Chen, Kui, Kong, Lingfei, Qian, Rongjun“…Based on the mRNA expression of HOXD10, GBM patients from TCGA database were divided into low- and high-HOXD10 expression groups to analyze the Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways, and construct a lncRNA-miRNA-mRNA network and a protein–protein interaction (PPI) network. …”
Publicado 2021
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10933por Chen, Liang, Lin, Yunhua, Liu, Guoqing, Xu, Rubin, Hu, Yiming, Xie, Jiaheng, Yu, Hongzhu“…KM survival analysis, univariate and multivariate COX regression analyses were employed to explore the prognostic impact of SSR1. Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis and Gene set enrichment analysis (GSEA) were implemented to reveal the underlying mechanism of SSR1. …”
Publicado 2021
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10934por Yuan, Zehu, Ge, Ling, Sun, Jingyi, Zhang, Weibo, Wang, Shanhe, Cao, Xiukai, Sun, Wei“…Protein protein interaction (PPI) network, Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses were implemented to investigate the potential functions of DETs. …”
Publicado 2021
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10935“…The gene ontology (GO) analysis of SRMS-associated immunomodulators and immune cell marker genes showed that they were mainly enriched in the immune microenvironment molecule-related signals. Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis of these genes indicated that they are involved in multiple cancer-related pathways. …”
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10936“…Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses were conducted to predict biological functions. …”
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10937por Lin, Jing, Zeng, Jing, Liu, Sha, Shen, Xin, Jiang, Nan, Wu, Yue-Song, Li, Hong, Wang, Long, Wu, Jian-Ming“…Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses were performed to elucidate the underling mechanism of DMAG against thrombocytopenia. …”
Publicado 2021
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10938“…Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) were used for the functional analysis. …”
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10939por Li, Jia-xin, Cao, Xun-jie, Huang, Yuan-yi, Li, Ya-ping, Yu, Zi-yuan, Lin, Min, Li, Qiu-ying, Chen, Ji-chun, Guo, Xu-guang“…METHODS: We downloaded the GSE33341 dataset from the GEO database and applied the weighted gene co-expression network analysis (WGCNA), from which we obtained some critical modules. Kyoto Encyclopedia of Genes and Genomes (KEGG) and Gene Ontology (GO) were applied to illustrate the biological functions of genes in these modules. …”
Publicado 2021
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10940por Wang, Yuehua, Gu, Wenwen, Kui, Fuguang, Gao, Fan, Niu, Yuji, Li, Wenwen, Zhang, Yaru, Guo, Zhenzhen, Du, Gangjun“…David database was used for gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis. …”
Publicado 2021
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