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1941por Kong, Lingjia, Tuomela, Soile, Hahne, Lauri, Ahlfors, Helena, Yli-Harja, Olli, Fadeel, Bengt, Lahesmaa, Riitta, Autio, Reija“…With NanoMiner it is possible to 1) search and plot the expression profiles of one or several genes of interest, 2) cluster the samples within the datasets, 3) find differentially expressed genes in various nanoparticle studies, 4) detect the nanoparticles causing differential expression of selected genes, 5) analyze enriched Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways and Gene Ontology (GO) terms for the detected genes and 6) search the expression values and differential expressions of the genes belonging to a specific KEGG pathway or Gene Ontology. …”
Publicado 2013
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1942por Bai, Xiaodong, Adams, Byron J., Ciche, Todd A., Clifton, Sandra, Gaugler, Randy, Kim, Kwi-suk, Spieth, John, Sternberg, Paul W., Wilson, Richard K., Grewal, Parwinder S.“…The 134 proteins contained mariner transposase domains, of which there are none in C. elegans, suggesting an invasion and expansion of mariner transposons in H. bacteriophora. Fewer Kyoto Encyclopedia of Genes and Genomes Orthologies in almost all metabolic categories were detected in the genome compared with 9 other sequenced nematode genomes, which may reflect dependence on the symbiont or insect host for these functions. …”
Publicado 2013
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1943por Kochi, Takahiro, Shimizu, Masahito, Ohno, Tomohiko, Baba, Atsushi, Sumi, Takafumi, Kubota, Masaya, Shirakami, Yohei, Tsurumi, Hisashi, Tanaka, Takuji, Moriwaki, Hisataka“…Male 6-week-old SHRSP, SHRSP-ZF, and control non-diabetic/normotensive Wister Kyoto/Izm (WKY) rats were given 2 weekly intraperitoneal injections of AOM (20 mg/kg body weight). …”
Publicado 2013
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1944por Sekimoto, Miho, Asai, Atsushi, Ohnishi, Motoki, Nishigaki, Etsuyo, Fukui, Tsuguya, Shimbo, Takuro, Imanaka, Yuichi“…METHODS: The subjects were diabetic patients at a single outpatient clinic in Kyoto. One of three case study vignettes (pneumonia, gangrene or cancer) was randomly assigned to each subject and, employing face-to-face interviews, the subjects were asked what their wishes would be as patients, for treatment information, participation in decision-making and family involvement. …”
Publicado 2004
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1945por Xu, Yahong, Luo, Shunwen, Liu, Yang, Li, Jian, Lu, Yi, Jia, Zhigang, Zhao, Qihua, Ma, Xiaoping, Yang, Minghui, Zhao, Yue, Chen, Ping, Guo, Yu“…RESULTS: There are two relationship types between bladder cancer and its related miRNAs: causal and unspecified. The Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment test showed that there were three pathways related to four miRNA targeted genes. …”
Publicado 2013
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1946“…The metabolic network datasets have been collected from the Kyoto Encyclopedia of Genes and Genomes (KEGG).…”
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1947por Liu, Rongning, Dong, Yanpeng, Fan, Guoqiang, Zhao, Zhenli, Deng, Minjie, Cao, Xibing, Niu, Suyan“…Eukaryotic clusters of orthologous groups, gene orthology, and the Kyoto Encyclopedia of Genes and Genomes annotations were performed of these unigenes. …”
Publicado 2013
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1948por Yoshida, Naohisa, Hosokawa, Toyoshi, Ishikawa, Takeshi, Yagi, Nobuaki, Kokura, Satoshi, Naito, Yuji, Nakanishi, Masayoshi, Kokuba, Yukihito, Otsuji, Eigo, Kuroboshi, Haruo, Taniwaki, Masafumi, Taguchi, Tetsuya, Hosoi, Hajime, Nakamura, Terukazu, Miki, Tsuneharu“…Colorectal cancer patients (N = 29) who received ≥4 weeks of Goshajinkigan for oxaliplatin-induced peripheral neuropathy during chemotherapy at Kyoto Prefectural University of Medicine were (Goshajinkigan group) compared to 44 patients who had not received Goshajinkigan during the same period (non-Goshajinkigan group). …”
Publicado 2013
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1949“…Administration of the UT antagonist SB-706375 evoked marked increases in GFR (baseline 0.38 ± 0.07 vs antagonist 0.76 ± 0.05 ml. min(-1). 100 g body weight(-1), P<0.05), urine flow and sodium excretion (baseline 2.5 ± 0.4 vs antagonist 9.1 ± 2.1 µmol. min(-1). 100 g body weight(-1), P<0.05) in the SHR. Normotensive Wistar-Kyoto rats showed little response to UT antagonism. …”
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1950por Carroll, Siobhan Yvonne, O’Mahony, Siobhain Mary, Grenham, Susan, Cryan, John Francis, Hyland, Niall Patrick“…Moreover, stress-sensitive Wistar Kyoto (WKY) rats, which display anxiety- and depressive-like behaviors, exhibit GI disturbances akin to those observed in stress-related GI disorders. …”
Publicado 2013
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1951por Kim, Sung-Eun, Ko, Il-Gyu, Hwang, Lakkyong, Choi, In-Young, Shin, Mal-Soon, Kim, Chang-Ju, Kim, Khae-Hawn“…RESULTS: The cystometric parameters, the basal pressure and duration of bladder contraction, were significantly increased in the SHR group as compared with the Wistar-Kyoto (WKY) group. The intercontraction interval also significantly decreased in the SHR group. …”
Publicado 2013
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1952“…Rats aged 4 weeks were assigned into 3 groups (n = 8/group): control Wistar Kyoto rats (WKY), SHR, and SHR receiving 2% NAC in drinking water. …”
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1953“…AESP and met-AESP (20 to 100 mg/kg) were intravenously administered into anaesthetized Wistar-Kyoto (WKY) and spontaneously hypertensive (SHR) rats. …”
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1954por Chang, Tzu-Hao, Wu, Shih-Lin, Wang, Wei-Jen, Horng, Jorng-Tzong, Chang, Cheng-Wei“…Three microarray data sets of breast cancer were collected from the Gene Expression Omnibus, and pathway information from the Kyoto Encyclopedia of Genes and Genomes was applied for discovering meaningful biological correlations. …”
Publicado 2014
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1955por Tseliou, Eleni, de Couto, Geoffrey, Terrovitis, John, Sun, Baiming, Weixin, Liu, Marbán, Linda, Marbán, Eduardo“…METHODS: Four groups were studied: 1) “Sham” (Wistar Kyoto rats with thoracotomy and ligature without infarction); 2) “MI” (proximal LAD ligation with peri-infarct injection of vehicle); 3) “MI+CSp” (MI with cardiospheres injected in the peri-infarct area); 4) “Small MI” (mid-LAD ligation only). …”
Publicado 2014
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1956“…Lewis rats are susceptible to AA following immunization with heat-killed Mycobacterium tuberculosis H37Ra, whereas Wistar-Kyoto (WKY) rats of the same MHC (major histocompatibility complex) haplotype are resistant. …”
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1957“…We mapped 9,125 unigenes onto 163 pathways using the Kyoto Encyclopedia of Genes and Genomes Pathway database. …”
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1958por Kanehisa, Minoru, Goto, Susumu, Sato, Yoko, Kawashima, Masayuki, Furumichi, Miho, Tanabe, Mao“…In the hierarchy of data, information and knowledge, computational methods play a major role in the initial processing of data to extract information, but they alone become less effective to compile knowledge from information. The Kyoto Encyclopedia of Genes and Genomes (KEGG) resource (http://www.kegg.jp/ or http://www.genome.jp/kegg/) has been developed as a reference knowledge base to assist this latter process. …”
Publicado 2014
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1959“…The assembled sequences were further annotated with gene ontology, cluster of orthologous group terms, and Kyoto encyclopedia of genes and genomes. In depth analysis was performed to identify genes putatively involved in immunity, detoxification, and energy metabolism. …”
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1960por Li, Meng-Yao, Wang, Feng, Xu, Zhi-Sheng, Jiang, Qian, Ma, Jing, Tan, Guo-Fei, Xiong, Ai-Sheng“…Potential miRNA-target genes were predicted and annotated by screening diverse protein databases, including Gene Ontology, Cluster of Orthologous Groups and Kyoto Encyclopedia of Genes and Genomes. Significant differential expression between the two varieties was seen for 221 miRNAs. qRT-PCR was used to analyze the abundance of six miRNAs under cold and heat stress conditions. …”
Publicado 2014
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