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20681
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20682por Leone, Ludovica, Mazzocchi, Alessandra, Maffeis, Laura, De Cosmi, Valentina, Agostoni, CarloEnlace del recurso
Publicado 2023
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20683
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20684
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20685por Kumar, Chirag K., Sands, Kirsty, Walsh, Timothy R., O’Brien, Seamus, Sharland, Mike, Lewnard, Joseph A., Hu, Hao, Srikantiah, Padmini, Laxminarayan, Ramanan“…The largest relative benefits are in Africa (Sierra Leone, Mali, Niger) and South-East Asia (Bangladesh) where vaccination could avert over 6% of all neonatal deaths. …”
Publicado 2023
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20686por Whitlock, Alexander O. B., Bird, Brian H., Ghersi, Bruno, Davison, Andrew J., Hughes, Joseph, Nichols, Jenna, Vučak, Matej, Amara, Emmanuel, Bangura, James, Lavalie, Edwin G., Kanu, Marilyn C., Kanu, Osman T., Sjodin, Anna, Remien, Christopher H., Nuismer, Scott L.“…Using a combination of phylogenetically structured simulations and Lassa virus sequences collected from humans and rodents in Sierra Leone, we demonstrate that existing methods do not fully correct for stratification, leading to elevated error rates. …”
Publicado 2023
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20687por Marchini, Mia, Paciulli, Maria, Broccardo, Lorenza, Tuccio, Maria Grazia, Scazzina, Francesca, Cirlini, Martina, Carini, Eleonora“…Three of them were chosen based on the best textural, nutritional (highest intake of energy, proteins, and micronutrients—iron, zinc and vitamin A), and economic (cheapest in Sierra Leone, Tanzania, Burundi, and Togo) features. The physicochemical properties, in vitro starch digestibility, total phenolic content, antioxidant capacity, and sensory acceptability were also measured for the samples. …”
Publicado 2023
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20688por Boubour, Jean, Jenson, Katherine, Richter, Hannah, Yarbrough, Josiah, Oden, Z. Maria, Schuler, Douglas A.“…Inspired by our sterile processing fieldwork at a district hospital in Sierra Leone in 2013, we built an autonomous, shipping-container-based sterile processing unit to address these deficiencies. …”
Publicado 2016
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20689“…Trends reveal that overweight and obesity are a growing problem among women and children in LMIC; as in Ghana, Kenya, Niger, Sierra Leone, Tanzania and Zimbabwe, where the prevalence among urban women is approaching 50 %. …”
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20690por Domi, Arban, Feldmann, Friederike, Basu, Rahul, McCurley, Nathanael, Shifflett, Kyle, Emanuel, Jackson, Hellerstein, Michael S., Guirakhoo, Farshad, Orlandi, Chiara, Flinko, Robin, Lewis, George K., Hanley, Patrick W., Feldmann, Heinz, Robinson, Harriet L., Marzi, Andrea“…Ebola virus (EBOV), isolate Makona, was the causative agent of the West African epidemic devastating predominantly Guinea, Liberia and Sierra Leone from 2013–2016. While several experimental vaccine and treatment approaches have been accelerated through human clinical trials, there is still no approved countermeasure available against this disease. …”
Publicado 2018
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20691por Boisen, Matthew L., Hartnett, Jessica N., Shaffer, Jeffrey G., Goba, Augustine, Momoh, Mambu, Sandi, John Demby, Fullah, Mohamed, Nelson, Diana K. S., Bush, Duane J., Rowland, Megan M., Heinrich, Megan L., Koval, Anatoliy P., Cross, Robert W., Barnes, Kayla G., Lachenauer, Anna E., Lin, Aaron E., Nekoui, Mahan, Kotliar, Dylan, Winnicki, Sarah M., Siddle, Katherine J., Gbakie, Michael, Fonnie, Mbalu, Koroma, Veronica J., Kanneh, Lansana, Kulakosky, Peter C., Hastie, Kathryn M., Wilson, Russell B., Andersen, Kristian G., Folarin, Onikepe O., Happi, Christian T., Sabeti, Pardis C., Geisbert, Thomas W., Saphire, Erica Ollmann, Khan, S. Humarr, Grant, Donald S., Schieffelin, John S., Branco, Luis M., Garry, Robert F.“…The field performance of recombinant antigen-based Lassa fever immunoassays was compared to that of quantitative polymerase chain assays (qPCRs) using samples from subjects meeting the case definition of Lassa fever presenting to Kenema Government Hospital in Sierra Leone. The recombinant Lassa virus (ReLASV) enzyme-linked immunosorbant assay (ELISA) for detection of viral antigen in blood performed with 95% sensitivity and 97% specificity using a diagnostic standard that combined results of the immunoassays and qPCR. …”
Publicado 2018
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20692por Scribante, Andrea, Montasser, Mona A., Radwan, Eman Saad, Bernardinelli, Luisa, Alcozer, Roberto, Gandini, Paola, Sfondrini, Maria Francesca“…Ti-6Al-4V titanium and stainless steel TADs of different manufacturers (Spider ScrewHDC; Mini Implants–Leone; Benefit–Orteam; Storm–Kristal) were evaluated. …”
Publicado 2018
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20693“…Drawing from examples in our health systems research in Tanzania and Sierra Leone, we elucidate how debriefings have allowed us to: enhance the skills of data collectors; gain immediate insights into the content of data; correct course amid unforeseen changes and challenges in the local context; strengthen the quality and trustworthiness of data in real time; and quickly share emerging data with stakeholders in programmatic, policy and academic spheres. …”
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20694por Rudge, Thomas L., Sankovich, Karen A., Niemuth, Nancy A., Anderson, Michael S., Badorrek, Christopher S., Skomrock, Nick D., Cirimotich, Chris M., Sabourin, Carol L.“…The need for an efficacious vaccine against highly pathogenic filoviruses was reinforced by the recent and devastating 2014–2016 outbreak of Ebola virus (EBOV) disease in Guinea, Sierra Leone, and Liberia that resulted in more than 10,000 casualties. …”
Publicado 2019
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20695“…WHO-coordinated multi-partner protocols to test investigational treatments, diagnostics, and vaccines are needed, by analogy to such protocols for Ebola during the unanticipated pan-epidemic in Guinea, Liberia, and Sierra Leone. Anticipating and preparing now for urban and rural Nipah outbreaks in nations with no experience with Nipah will help avoid the potential for what the United Nations 2016 report on Ebola in West Africa called a “preventable tragedy”.…”
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20696por Elfiky, Abdo A.“…In the 2014 and 2015 outbreak, more than 28,000 infections were reported by the World Health Organization, with about 11,300 deaths in Guinea, Liberia, and Sierra Leone. Heat shock protein A5 (HSPA5), termed also GRP78, is a host cell chaperone protein responsible for the unfolded protein response in the endoplasmic reticulum. …”
Publicado 2020
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20697por Boisen, Matthew L., Uyigue, Eghosa, Aiyepada, John, Siddle, Katherine J., Oestereich, Lisa, Nelson, Diana K. S., Bush, Duane J., Rowland, Megan M., Heinrich, Megan L., Eromon, Philomena, Kayode, Adeyemi T., Odia, Ikponmwosa, Adomeh, Donatus I., Muoebonam, Ekene B., Akhilomen, Patience, Okonofua, Grace, Osiemi, Blessing, Omoregie, Omigie, Airende, Michael, Agbukor, Jacqueline, Ehikhametalor, Solomon, Aire, Chris Okafi, Duraffour, Sophie, Pahlmann, Meike, Böhm, Wiebke, Barnes, Kayla G., Mehta, Samar, Momoh, Mambu, Sandi, John Demby, Goba, Augustine, Folarin, Onikepe A., Ogbaini-Emovan, Ephraim, Asogun, Danny A., Tobin, Ekaete A., Akpede, George O., Okogbenin, Sylvanus A., Okokhere, Peter O., Grant, Donald S., Schieffelin, John S., Sabeti, Pardis C., Günther, Stephan, Happi, Christian T., Branco, Luis M., Garry, Robert F.“…LF is endemic in Nigeria, Sierra Leone and other West African countries. Diagnosis of LASV infection is challenged by the genetic diversity of the virus, which is greatest in Nigeria. …”
Publicado 2020
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20698por Pavlin, Boris I., Hall, Andrew, Hajek, Jan, Raja, Muhammad Ali, Sharma, Vikas, Ramadan, Otim Patrick, Mishra, Sharmistha, Rangel, Audrey, Kitching, Aileen, Roper, Katrina, O’Dempsey, Tim, Starkulla, Judith, Parry, Amy Elizabeth, Kamara, Rashida, Wurie, Alie H.“…METHODS: We conducted a review of medical records and EVD investigation reports from three districts in Sierra Leone. We report the clinical presentations and maternal and fetal outcomes of six pregnant women with atypical EVD, and subsequent transmission events from perinatal care. …”
Publicado 2020
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20699“…METHODS: Off-label treated fractures, the implant used instead, and the reason for off-label treatment were investigated in 367 injuries over a three month period in an NGO hospital in Sierra Leone. RESULTS: Twenty-seven fractures were treated off-label with mostly K-wires (88.89%) and external fixators (51.85%). …”
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20700por Seytre, Bernard, Barros, Cristano, Bona, Philip, Fall, Babacar, Konaté, Blahima, Rodrigues, Amabelia, Varela, Octávio, Blé Yoro, Marcel“…We conducted a quantitative socio-anthropological study of the knowledge of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and perception of the prevention messages in Burkina Faso, Cabo Verde, Guinea-Bissau, Ivory Coast, and Sierra Leone. There are widespread erroneous ideas regarding the transmission of and the protection against COVID-19. …”
Publicado 2021
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