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  1. 381
    por Antinori, Andrea, Mazzotta, Valentina, Vita, Serena, Carletti, Fabrizio, Tacconi, Danilo, Lapini, Laura Emma, D’Abramo, Alessandra, Cicalini, Stefania, Lapa, Daniele, Pittalis, Silvia, Puro, Vincenzo, Rivano Capparuccia, Marco, Giombini, Emanuela, Gruber, Cesare Ernesto Maria, Garbuglia, Anna Rosa, Marani, Alessandra, Vairo, Francesco, Girardi, Enrico, Vaia, Francesco, Nicastri, Emanuele, Agresta, Alessandro, Baldini, Francesco, Bartoli, Tommaso Ascoli, Beccacece, Alessia, Bellagamba, Rita, Bettini, Aurora, Bevilacqua, Nazario, Camici, Marta, Colavita, Francesca, Corpolongo, Angela, De Carli, Gabriella, De Zottis, Federico, Faraglia, Francesca, Francalancia, Massimo, Fusco, Concetta Maria, Gagliardini, Roberta, Gebremeskel, Saba, Giancola, Maria Letizia, Gramigna, Giulia, Grilli, Elisabetta, Grisetti, Susanna, Lanini, Simone, Maffongelli, Gaetano, Mariano, Andrea, Mastrorosa, Ilaria, Matusali, Giulia, Meschi, Silvia, Minosse, Claudia, Moccione, Martina, Mondi, Annalisa, Mondillo, Vanessa, Orchi, Nicoletta, Ottou, Sandrine, Pinnetti, Carmela, Rosati, Silvia, Rueca, Martina, Scorzolini, Laura, Specchiarello, Eliana, Vergori., Alessandra
    Publicado 2022
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    Epidemiological, clinical and virological characteristics of four cases of monkeypox support transmission through sexual contact, Italy, May 2022
  2. 382
    por De Carli, Gabriella, Carletti, Fabrizio, Spaziante, Martina, Gruber, Cesare Ernesto Maria, Rueca, Martina, Spezia, Pietro Giorgio, Vantaggio, Valentina, Barca, Alessandra, De Liberato, Claudio, Romiti, Federico, Scicluna, Maria Teresa, Vaglio, Stefania, Feccia, Mariano, Di Rosa, Enrico, Gianzi, Francesco Paolo, Giambi, Cristina, Scognamiglio, Paola, Nicastri, Emanuele, Girardi, Enrico, Maggi, Fabrizio, Vairo, Francesco, Di Donato, Michele, Baldin, Gianmaria, Giovannenze, Francesca, Raffaelli, Francesca, Salvatore, Lucia, Sestito, Luisa, Taddei, Eleonora, Cingolani, Antonella, Fantoni, Massimo, Vita, Serena, Al Moghazi, Samir, Boumis, Evangelo, Corpolongo, Angela, Rianda, Alessia, Furino, Ermenegildo, Gianni, Cristiana, Barletta, Cinzia, Pendenza, Alessio, Esterini, Giorgio, Mellace, Flavio, Vivaldi, Fabio, Gentile, Adele, Torchia, Saul L., Mormone, Federica, Barbato, Domenico, Mangiagli, Franca, Giammattei, Roberto, Zerbetto, Alessandro, Ruta, Amilcare, Malatesta, Giorgio Nicolò, Tonziello, Gilda, Fusco, Maria Concetta, Agresta, Alessandro, De Santis, Claudia, D’Amato, Maurizio, Pitti, Giovanni, Matusali, Giulia, Colavita, Francesca, Lalle, Eleonora, Bordi, Licia, Meschi, Silvia, Lapa, Daniele, Garbuglia, Anna Rosa, Mariotti, Davide
    Publicado 2023
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    Outbreaks of autochthonous Dengue in Lazio region, Italy, August to September 2023: preliminary investigation
  3. 383
    por Nicolau, José Carlos, Feitosa, Gilson Soares, Petriz, João Luiz, Furtado, Remo Holanda de Mendonça, Précoma, Dalton Bertolim, Lemke, Walmor, Lopes, Renato Delascio, Timerman, Ari, Marin, José A., Bezerra, Luiz, Gomes, Bruno Ferraz de Oliveira, Santos, Eduardo Cavalcanti Lapa, Piegas, Leopoldo Soares, Soeiro, Alexandre de Matos, Negri, Alexandre Jorge de Andrade, Franci, Andre, Markman, Brivaldo, Baccaro, Bruno Mendonça, Montenegro, Carlos Eduardo Lucena, Rochitte, Carlos Eduardo, Barbosa, Carlos José Dornas Gonçalves, Virgens, Cláudio Marcelo Bittencourt das, Stefanini, Edson, Manenti, Euler Roberto Fernandes, Lima, Felipe Gallego, Monteiro, Francisco das Chagas, Correa, Harry, Pena, Henrique Patrus Mundim, Pinto, Ibraim Masciarelli Francisco, Falcão, João Luiz de Alencar Araripe, Sena, Joberto Pinheiro, Peixoto, José Maria, de Souza, Juliana Ascenção, da Silva, Leonardo Sara, Maia, Lilia Nigro, Ohe, Louis Nakayama, Baracioli, Luciano Moreira, Dallan, Luís Alberto de Oliveira, Dallan, Luis Augusto Palma, Mattos, Luiz Alberto Piva e, Bodanese, Luiz Carlos, Ritt, Luiz Eduardo Fonteles, Canesin, Manoel Fernandes, Rivas, Marcelo Bueno da Silva, Franken, Marcelo, Magalhães, Marcos José Gomes, de Oliveira, Múcio Tavares, Filgueiras, Nivaldo Menezes, Dutra, Oscar Pereira, Coelho, Otávio Rizzi, Leães, Paulo Ernesto, Rossi, Paulo Roberto Ferreira, Soares, Paulo Rogério, Lemos, Pedro Alves, Farsky, Pedro Silvio, Cavalcanti, Rafael Rebêlo C., Alves, Renato Jorge, Kalil, Renato Abdala Karam, Esporcatte, Roberto, Marino, Roberto Luiz, Giraldez, Roberto Rocha Corrêa Veiga, Meneghelo, Romeu Sérgio, Lima, Ronaldo de Souza Leão, Ramos, Rui Fernando, Falcão, Sandra Nivea dos Reis Saraiva, Dalçóquio, Talia Falcão, Lemke, Viviana de Mello Guzzo, Chalela, William Azem, Mathias, Wilson
    Publicado 2021
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    Diretrizes da Sociedade Brasileira de Cardiologia sobre Angina Instável e Infarto Agudo do Miocárdio sem Supradesnível do Segmento ST – 2021
  4. 384
    por Mondi, Annalisa, Lorenzini, Patrizia, Castilletti, Concetta, Gagliardini, Roberta, Lalle, Eleonora, Corpolongo, Angela, Valli, Maria Beatrice, Taglietti, Fabrizio, Cicalini, Stefania, Loiacono, Laura, Di Gennaro, Francesco, D’Offizi, Gianpiero, Palmieri, Fabrizio, Nicastri, Emanuele, Agrati, Chiara, Petrosillo, Nicola, Ippolito, Giuseppe, Vaia, Francesco, Girardi, Enrico, Capobianchi, Maria Rosaria, Antinori, Andrea, Zito, Sara, Abbonizio, Maria Alessandra, Abdeddaim, Amina, Agostini, Elisabetta, Agrati, Chiara, Albarello, Fabrizio, Amadei, Gioia, Amendola, Alessandra, Antinori, Andrea, Antonica, Maria Assunta, Antonini, Mario, Bartoli, Tommaso Ascoli, Baldini, Francesco, Barbaro, Raffaella, Bartolini, Barbara, Bellagamba, Rita, Benigni, Martina, Bevilacqua, Nazario, Biava, Gianluigi, Bibas, Michele, Bordi, Licia, Bordoni, Veronica, Boumis, Evangelo, Branca, Marta, Buonomo, Rosanna, Busso, Donatella, Camici, Marta, Campioni, Paolo, Canichella, Flaminia, Capobianchi, Maria Rosaria, Capone, Alessandro, Caporale, Cinzia, Caraffa, Emanuela, Caravella, Ilaria, Carletti, Fabrizio, Castilletti, Concetta, Cataldo, Adriana, Cerilli, Stefano, Cerva, Carlotta, Chiappini, Roberta, Chinello, Pierangelo, Cianfarani, Maria Assunta, Ciaralli, Carmine, Cimaglia, Claudia, Cinicola, Nicola, Ciotti, Veronica, Cicalini, Stefania, Colavita, Francesca, Corpolongo, Angela, Cristofaro, Massimo, Curiale, Salvatore, D’Abramo, Alessandra, Dantimi, Cristina, De Angelis, Alessia, De Angelis, Giada, De Palo, Maria Grazia, De Zottis, Federico, Di Bari, Virginia, Di Lorenzo, Rachele, Di Stefano, Federica, D’Offizi, Gianpiero, Donno, Davide, Evangelista, Francesca, Faraglia, Francesca, Farina, Anna, Ferraro, Federica, Fiorentini, Lorena, Frustaci, Andrea, Fusetti, Matteo, Galati, Vincenzo, Gagliardini, Roberta, Gallì, Paola, Garotto, Gabriele, Gaviano, Ilaria, Tekle, Saba Gebremeskel, Giancola, Maria Letizia, Giansante, Filippo, Giombini, Emanuela, Granata, Guido, Greci, Maria Cristina, Grilli, Elisabetta, Grisetti, Susanna, Gualano, Gina, Iacomi, Fabio, Iaconi, Marta, Iannicelli, Giuseppina, Inversi, Carlo, Ippolito, Giuseppe, Lalle, Eleonora, Lamanna, Maria Elena, Lanini, Simone, Lapa, Daniele, Lepore, Luciana, Libertone, Raffaella, Lionetti, Raffaella, Liuzzi, Giuseppina, Loiacono, Laura, Lucia, Andrea, Lufrani, Franco, Macchione, Manuela, Maffongelli, Gaetano, Marani, Alessandra, Marchioni, Luisa, Mariano, Andrea, Marini, Maria Cristina, Maritti, Micaela, Mastrobattista, Annelisa, Mastrorosa, Ilaria, Matusali, Giulia, Mazzotta, Valentina, Mencarini, Paola, Meschi, Silvia, Messina, Francesco, Micarelli, Sibiana, Mogavero, Giulia, Mondi, Annalisa, Montalbano, Marzia, Montaldo, Chiara, Mosti, Silvia, Murachelli, Silvia, Musso, Maria, Nardi, Michela, Navarra, Assunta, Nicastri, Emanuele, Nocioni, Martina, Noto, Pasquale, Noto, Roberto, Oliva, Alessandra, Onnis, Ilaria, Ottou, Sandrine, Palazzolo, Claudia, Pallini, Emanuele, Palmieri, Fabrizio, Palombi, Giulio, Pareo, Carlo, Passeri, Virgilio, Pelliccioni, Federico, Penna, Giovanna, Petrecchia, Antonella, Petrone, Ada, Petrosillo, Nicola, Pianura, Elisa, Pinnetti, Carmela, Pisciotta, Maria, Piselli, Pierluca, Pittalis, Silvia, Pontarelli, Agostina, Proietti, Costanza, Puro, Vincenzo, Ramazzini, Paolo Migliorisi, Rianda, Alessia, Rinonapoli, Gabriele, Rosati, Silvia, Rubino, Dorotea, Rueca, Martina, Ruggeri, Alberto, Sacchi, Alessandra, Sampaolesi, Alessandro, Sanasi, Francesco, Santagata, Carmen, Scarabello, Alessandra, Scarcia, Silvana, Schininà, Vincenzo, Scognamiglio, Paola, Scorzolini, Laura, Stazi, Giulia, Strano, Giacomo, Taglietti, Fabrizio, Taibi, Chiara, Taloni, Giorgia, Nardi, Tetaj, Tonnarini, Roberto, Topino, Simone, Tozzi, Martina, Vaia, Francesco, Vairo, Francesco, Valli, Maria Beatrice, Vergori, Alessandra, Vincenzi, Laura, Visco-Comandini, Ubaldo, Vita, Serena, Vittozzi, Pietro, Zaccarelli, Mauro, Zanetti, Antonella, Zito, Sara
    Publicado 2021
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    Risk and predictive factors of prolonged viral RNA shedding in upper respiratory specimens in a large cohort of COVID-19 patients admitted to an Italian reference hospital
  5. 385
    “…-LAPA_LBNP. All these findings suggested that the developed modified LBNP could potentiate anti-Survivin siRNA and LAPA anti-cancer activity.…”
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    Formulation of Lipid-Based Nanoparticles for Simultaneous Delivery of Lapatinib and Anti-Survivin siRNA for HER2+ Breast Cancer Treatment
  6. 386
    “…Here we report how LapD differentially controls maintenance and release of LapA: c-di-GMP binding to LapD promotes interaction with and inhibition of the periplasmic protease LapG, which targets the N-terminus of LapA. …”
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    A c-di-GMP Effector System Controls Cell Adhesion by Inside-Out Signaling and Surface Protein Cleavage
  7. 387
    “…Analysis demonstrated increased operative times in the OpenA [OpenA: 96.4 ± 37.2 vs LapA 88.47 ± 33 min, p = 0.035], with shorter overall length of stay in the LapA group [OpenA 13 ± 12 vs LapA 10.3 ± 11.4 days p = 0.038]. …”
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    Perforated peptic ulcer (PPU) treatment: an Italian nationwide propensity score-matched cohort study investigating laparoscopic vs open approach
  8. 388
    “…The released SOD-Fe(0) and Lapa were further endocytosed by tumor cells and the Lapa produces superoxide anion (O(2)(-•)) through the catalysis of NQO1 that is overexpressed in tumor cells, while O(2)(-•) is converted to H(2)O(2) via SOD. …”
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    Advanced biomimetic nanoreactor for specifically killing tumor cells through multi-enzyme cascade
  9. 389
    “…US: p > 0.05) than with air polishing (LAPA-1/LAPA-2: 34.06 ± 29.48%/17.09 ± 18.85%; LAPA-1 vs. …”
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    Results of an experimental study of subgingival cleaning effectiveness in the furcation area
  10. 390
    “…Mean operative time was shorter in lapa-group (215.5 ± 121.84 minutes vs. 282.30 ± 80.34 minutes, P = 0.001), mean intraoperative transfusion rate and total amount were small in lapa-group (24.28%, 148.57 ± 3,354.98 mL vs. 40.78%, 311.71 ± 477.01 mL). …”
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    The comparison of oncologic and clinical outcomes of laparoscopic liver resection for hepatocellular carcinoma
  11. 391
    “…Here, we demonstrate that the master regulator FleQ modulates biofilm formation by post-transcriptionally regulating the production of LapA and MapA. We find that a ΔfleQ mutant has a biofilm formation defect compared to the WT strain, which is attributed in part to a decrease in LapA and MapA production, despite the ΔfleQ mutant having increased levels of lapA and mapA transcripts compared to the WT strain. …”
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    The Regulator FleQ Post-Transcriptionally Regulates the Production of RTX Adhesins by Pseudomonas fluorescens
  12. 392
    “…In vivo gene expression analysis showed that (p)ppGpp positively regulates transcription of bifA, and negatively regulates transcription of lapA and the lapBC, and lapE operons, encoding a LapA-specific secretion system. …”
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    The stringent response promotes biofilm dispersal in Pseudomonas putida
  13. 393
    “…Here composite nanocrystals of PTX and LAPA (cNC) were designed with a ratio of 2:1 (w/w), which was their intracellular ratio at the best synergistic efficacy on a drug-resistant cancer cell line (MCF-7/ADR). …”
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    Synergistic Antitumor Effects on Drug-Resistant Breast Cancer of Paclitaxel/Lapatinib Composite Nanocrystals
  14. 394
    “…The Lapa-Her-Closure was removed after the PDS thread was grasped with robotic forceps. …”
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    A safe, reliable, and efficient robot-assisted port site closure for robot-assisted gastrectomy
  15. 395
    “…LapA would serve as potential target to monitor chronic wound infections by P. aeruginosa biofilms. …”
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    Transcriptional analysis and target genes discovery of Pseudomonas aeruginosa biofilm developed ex vivo chronic wound model
  16. 396
    por Li, Xin, Jia, Xiaoqian, Niu, Hu
    Publicado 2018
    “…PATIENTS AND METHODS: Lapa and DOX were loaded into NLC to prepare LDNLC using melted ultrasonic dispersion method. …”
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    Nanostructured lipid carriers co-delivering lapachone and doxorubicin for overcoming multidrug resistance in breast cancer therapy
  17. 397
    “…Herein, we report a self-amplified nanocatalytic system (ZIF67/Ola/Lapa) to co-deliver the PARP inhibitor Olaparib (Ola) and NQO1-bioactivatable drug Lapa for sustainable H(2)O(2) production and augmented CDT (“1 + 1 + 1 > 3”). …”
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    A self-amplified nanocatalytic system for achieving “1 + 1 + 1 > 3” chemodynamic therapy on triple negative breast cancer
  18. 398
    “…Furthermore, whitefly infestation of transgenic LapA1:GUS tomato plants showed that whitefly feeding did not activate the LapA1 promoter, although crushing of the leaf lamina increased GUS activity up to 40 fold. …”
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    Tomato Pathogenesis-related Protein Genes are Expressed in Response to Trialeurodes vaporariorum and Bemisia tabaci Biotype B Feeding
  19. 399
    “…While most of the changes in gene expression after wounding in LapA-SI leaves were similar to WT, overall responses were delayed in the LapA-SI leaves. …”
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    Microarray Analysis of Tomato’s Early and Late Wound Response Reveals New Regulatory Targets for Leucine Aminopeptidase A
  20. 400
    por Chang, Na, Zhao, Yufei, Ge, Ning, Qian, Liting
    Publicado 2020
    “…Within the acidic endo-lysosomal environment, PHis protonation facilitated the escape of the PLP-NPs from the lysosome and release of Lapa. The released Lapa generated a large amount of ROS, consumed ATP, and downregulated P-glycoprotein (P-gp) production through the activity of NQO1, an enzyme that is specifically overexpressed in tumor cells. …”
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    A pH/ROS cascade-responsive and self-accelerating drug release nanosystem for the targeted treatment of multi-drug-resistant colon cancer
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