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321“…Here, by using Drosophila melanogaster NHEJ mutants, we show that linear intron RNA retrohoming occurs by major Lig4-dependent and minor Lig4-independent mechanisms, which appear to be related to classical and alternate NHEJ, respectively. …”
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322por Kukshal, Vandna, Khanam, Taran, Chopra, Deepti, Singh, Nidhi, Sanyal, Sabyasachi, Ramachandran, Ravishankar“…Overall the results suggest that other as-yet-unidentified factors may mediate interactions between the clamp, LigA and DNA in mycobacteria.…”
Publicado 2012
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323por Qi, Yiping, Zhang, Yong, Zhang, Feng, Baller, Joshua A., Cleland, Spencer C., Ryu, Yungil, Starker, Colby G., Voytas, Daniel F.“…We achieved a fivefold to 16-fold enhancement in HR-based GT in a ku70 mutant and a threefold to fourfold enhancement in GT in the lig4 mutant. Although the NHEJ mutagenesis frequency was not significantly changed in ku70 or lig4, DNA repair was shifted to microhomology-dependent alternative NHEJ. …”
Publicado 2013
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324por Soni, Aashish, Siemann, Maria, Grabos, Martha, Murmann, Tamara, Pantelias, Gabriel E., Iliakis, George“…Parp-1, DNA-ligases 1 (Lig1) and 3 (Lig3), and Xrcc1 are implicated in B-NHEJ. …”
Publicado 2014
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325por Johnston, V. E., Borsato, A., Frisia, S., Spötl, C., Dublyansky, Y., Töchterle, P., Hellstrom, J. C., Bajo, P., Edwards, R. L., Cheng, H.“…This anomaly is significantly higher than any low-altitude reconstructions for the LIG in Europe, implying elevation-dependent warming during the LIG. …”
Publicado 2018
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326“…The transport of PF in A→B direction significantly increased when co-administrated with increasing concentrations of LIG, SENI and SENA. An increased cellular accumulation of Rho 123 and Western blot analysis indicated that LIG, SENI and SENA had increased the transport of PF in the BBB models attribute to down-regulate P-gp expression. …”
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327“…Disruption of the Lig4 gene in CH12F3 cells severely inhibits the initial rate of CSR and causes a late cell proliferation defect under cytokine stimulation. …”
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328“…S. solfataricus PCNA is a heterotrimer, with each subunit having a distinct specificity for binding PolB1, Fen1 or Lig1. Our data demonstrate that the most efficient coupling of activities occurs when a single PCNA ring organises PolB1, Fen1 and Lig1 into a complex.…”
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329por Jian, Jhih-Wei, Elumalai, Pavadai, Pitti, Thejkiran, Wu, Chih Yuan, Tsai, Keng-Chang, Chang, Jeng-Yih, Peng, Hung-Pin, Yang, An-Suei“…The prediction accuracy of the ISMBLab-LIG predictors is comparable to that of the best LBS predictors benchmarked on several well-established testing datasets. …”
Publicado 2016
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330por Jiao, Lishi, Chua, Zhong Yang, Moon, Seung Ki, Song, Jie, Bi, Guijun, Zheng, Hongyu, Lee, Byunghoon, Koo, Jamyeong“…An interdigital electrode capacitor was written on the AM parts to demonstrate the capability of LIG. Cyclic voltammetry, galvanostatic charge-discharge, and cyclability testing demonstrated good electrochemical performance of the LIG capacitor. …”
Publicado 2019
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331por Dai, Peng, Liang, Mengke, Ma, Xiaofeng, Luo, Yanlong, He, Ming, Gu, Xiaoli, Gu, Qun, Hussain, Imtiaz, Luo, Zhenyang“…Each lignin-based flame retardant (Lig) was quantitatively added to a fixed amount of epoxy resin (EP), to make a Lig/EP composite. …”
Publicado 2020
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332“…The synergistic effect of bimetallic Ni–Co–S and the LIG with the 2D structure results in the excellent electrochemical performance. …”
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333“…Moreover, lignin in the form of nanoparticles (LigNPs) presents advantages over bulk lignin, such as higher reactivity due to its larger surface-to-volume ratio. …”
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334por Qu, Chenkai, Lu, Meilan, Zhang, Ziyan, Chen, Shangbi, Liu, Dewen, Zhang, Dawei, Wang, Jing, Sheng, Bin“…In this work, we propose a flexible capacitive pressure sensor made entirely of thermoplastic polyurethane (TPU) and laser-induced graphene (LIG) derived from wood. The capacitive pressure sensor consisted of a flexible LIG/TPU electrode (LTE), an LIG/TPU electrode with a microhole array, and a dielectric layer of TPU with microcone array molded from a laser-engraved hole array on wood, which provided high sensitivity (0.11 kPa(−1)), an ultrawide pressure detection range (20 Pa to 1.4 MPa), a fast response (~300 ms), and good stability (>4000 cycles, at 0–35 kPa). …”
Publicado 2023
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335por Ochi, Takashi, Sibanda, Bancinyane Lynn, Wu, Qian, Chirgadze, Dimitri Y., Bolanos-Garcia, Victor M., Blundell, Tom L.“…A ring-shaped Ku70/Ku80 heterodimer forms first at broken DNA ends, DNA-dependent protein kinase catalytic subunit (DNA-PKcs) binds to mediate synapsis and nucleases process DNA overhangs. DNA ligase IV (LigIV) is recruited as a complex with XRCC4 for ligation, with XLF/Cernunnos, playing a role in enhancing activity of LigIV. …”
Publicado 2010
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336por Cerqueira, Gustavo M., Souza, Natalie M., Araújo, Eduardo R., Barros, Aline T., Morais, Zenaide M., Vasconcellos, Sílvio A., Nascimento, Ana L. T. O.“…The results obtained are in agreement with LigA expression from the L. interrogans Fiocruz L1-130 strain. …”
Publicado 2011
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337por Li, Zhongdao, Wen, Jikai, Lin, Yaning, Wang, Shihua, Xue, Peng, Zhang, Zhiping, Zhou, Ying, Wang, Xiao, Sui, Li, Bi, Li-Jun, Zhang, Xian-En“…Our results suggest that Sir2 may function closely together with Ku and LigD in the nonhomologous end-joining pathway in mycobacteria.…”
Publicado 2011
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338por Erakovic, Sanja, Jankovic, Ana, Tsui, Gary C. P., Tang, Chak-Yin, Miskovic-Stankovic, Vesna, Stevanovic, Tatjana“…The antimicrobial efficiency of Ag/HAP/Lig was confirmed by its higher reduction of bacteria Staphylococcus aureus TL (S. aureus TL) than of HAP/Lig coating. …”
Publicado 2014
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339por Normanno, Davide, Négrel, Aurélie, de Melo, Abinadabe J, Betzi, Stéphane, Meek, Katheryn, Modesti, Mauro“…Independently of LIG4, XLF also associates with XRCC4 to form filaments that bridge DNA. …”
Publicado 2017
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340por Pereira, Sónia O., Santos, Nuno F., Carvalho, Alexandre F., Fernandes, António J. S., Costa, Florinda M.“…More recently, laser-induced graphene (LIG), a graphene derivative, appears as a great candidate due to its superior electron transfer characteristics, high surface area and simplicity in its synthesis. …”
Publicado 2021
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