“…A compound heterozygous variant L19W/K635fs in the LIG4 gene was identified. Patient 2 presented at the age of 16 with recurrent infections. …”
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“…The retention time for LIG, HYD, and KET were 1.54, 2.57, and 5.78 min, correspondingly. …”
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“…The subjects were police trainees [18 in a moderate intensity exercise group (MIG) and 19 in a low intensity exercise group (LIG)] recruited for a 6-month physical training course (261.8 Kcalorie, 3.6 metabolic equivalent in MIG and 153.6 Kcalorie, 2.1 metabolic equivalent in LIG). …”
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“…Forty-five male Iranian adults aged 65–80 years were selected according to the eligibility criteria and randomly assigned to a low-intensity group (LIG) (40–50% of maximum heart rate), moderate-intensity group (MIG) (60–70% of maximum heart rate) and control group (CG). …”
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“…Further, CON and CON + LIG treatments were distinguishable using F50 and F95 measures (p = 0.02, p = 0.04, respectively). …”
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“…Genetic modification of Rhodococcus jostii RHA1 was carried out in order to optimise the production of pyridine-2,4-dicarboxylic acid and pyridine-2,5-dicarboxylic acid bioproducts from lignin or lignocellulose breakdown, via insertion of either the Sphingobium SYK-6 ligAB genes or Paenibacillus praA gene respectively. …”
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“…In contrast, anti-β(2)GPI/oxLig-1 autoantibodies were generated only in APS and were strongly associated with arterial thrombosis. …”
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“…We report here the cloning, expression and purification of NAD(+)-dependent DNA ligase of Wolbachia endosymbiont of B. malayi (wBm-LigA) for its molecular characterization. wBm-LigA has all the domains that are present in nearly all the eubacterial NAD(+)-dependent DNA ligases such as N-terminal adenylation domain, OB fold, helix-hairpin-helix (HhH) and BRCT domain except zinc-binding tetracysteine domain. …”
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“…Mechanistically, telomere fusions require either the classical non-homologous end-joining (C-NHEJ) pathway dependent on Ku70/80 and LIG4, or the alternative non-homologous end-joining (A-NHEJ), which relies on PARP1 and LIG3. …”
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“…In healthy neurons, FUS protects the genome by facilitating PARP1-dependent recruitment of XRCC1/DNA Ligase IIIα (LigIII) to oxidized genome sites and activating LigIII via direct interaction. …”
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“…The first method employs the 3′-exonuclease activity of T4 DNA polymerase (T4 pol), Taq DNA polymerase (Taq pol), and Taq DNA ligase (Taq lig) in a two-step thermocycled reaction. The second method uses 3′-exonuclease III (ExoIII), antibody-bound Taq pol, and Taq lig in a one-step thermocycled reaction. …”
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“…In this work, we introduce DeepLigBuilder, a novel deep learning-based method for de novo drug design that generates 3D molecular structures in the binding sites of target proteins. …”
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“…In this work, the optimization and fabrication of micro-supercapacitors (MSCs) by means of laser-induced interdigital structured graphene electrodes (LIG) has been reported. The flexible and scalable MSCs are fabricated by CO(2)-laser structuring of polyimide-based Kapton (®) HN foils at ambient temperature yielding interdigital LIG-electrodes and using polymer gel electrolyte (PGE) produced by polypropylene carbonate (PPC) embedded ionic liquid of 1-ethyl-3-methyl-imidazolium-trifluoromethansulphonate [EMIM][OTf]. …”
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“…Our data indicate that LIG3-mediated telomere fusion is important in facilitating clonal evolution.…”
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“…Herein, simultaneous patterning and microstructuring of laser-induced graphene (LIG) on a renewable biomass resource, bamboo, by a laser-based graphitization technique was demonstrated. …”
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“…Manufacturing an entire LIG array takes less than one minute and costs about 0.11 yuan in materials, making it suitable for mass production. …”
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“…The photochemically synthesized spherical laser-induced MXene (Ti(3)C(2)T(x))-derived oxide nanoparticles uniformly attached to laser-induced graphene (LIG) act as active electrode materials for micro-SCs. …”
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“…Most of this effect resides within the CD103(+) subset of the E-lig(+) Th population, in which donor CCR4(+/+) cells can outnumber CCR4(−/−) cells by >12-fold. …”
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“…Although each β-etherase cleaves β-guaiacyl and β-syringyl substrates, we have found that each is stereospecific for a given β-enantiomer in a racemic substrate; LigE and LigP β-etherase homologues exhibited stereospecificity toward β(R)-enantiomers whereas LigF and its homologues exhibited β(S)-stereospecificity. …”
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