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321por Manichaikul, Ani, Wang, Xin-Qun, Li, Li, Erdmann, Jeanette, Lettre, Guillaume, Bis, Joshua C., Waterworth, Dawn, Cushman, Mary, Jenny, Nancy S., Post, Wendy S., Palmas, Walter, Tsai, Michael Y., Wallentin, Lars, White, Harvey, Schunkert, Heribert, O’Donnell, Christopher J., Herrington, David M., Rich, Stephen S., O’Donoghue, Michelle L., Rodriguez, Annabelle“…SUMMARY: SCARB1 rs10846744 is significantly associated with Lp-PLA(2) activity, atherosclerosis, and CVD events, but Lp-PLA(2) activity is not a mediator in the association of rs10846744 with cIMT in MESA.…”
Publicado 2018
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322por Kathad, Umesh, Kulkarni, Aditya, McDermott, Joseph Ryan, Wegner, Jordan, Carr, Peter, Biyani, Neha, Modali, Rama, Richard, Jean-Philippe, Sharma, Panna, Bhatia, Kishor“…In agreement with the perceived mechanism of action of LP-184, PTGR1 emerged as the top weighted gene. …”
Publicado 2021
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323por Robson, Emma, Kamper, Steven J., Hall, Alix, Lee, Hopin, Davidson, Simon, da Silva, Priscilla Viana, Gleadhill, Connor, Williams, Christopher M.“…A total of 346 adults with low back pain were recruited from the Newcastle and Hunter region between September 2017 and November 2019 and randomised to either HeLP or usual care. HeLP is a 6-month intervention with participant outcomes measured at weeks 6, 12, 26 and 52 post randomisation. …”
Publicado 2021
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324por Fidilio, Annamaria, Grasso, Margherita, Turnaturi, Rita, Caruso, Giuseppe, Spitale, Federica Maria, Vicario, Nunzio, Parenti, Rosalba, Spoto, Salvatore, Musso, Nicolò, Marrazzo, Agostino, Chiechio, Santina, Caraci, Filippo, Pasquinucci, Lorella, Parenti, Carmela“…In the present study, we examined the correlation between anti-allodynic effect of LP2, a dual-target MOPr/DOPr agonist, and TGF-β1 signalling in the chronic constriction injury (CCI) model. …”
Publicado 2021
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325“…The levels of serum LP-PLA2 and sST2 are closely related to the degree of patients' illness, among which the combined prediction of AHF patients with LP-PLA2 and sST2 has the highest value, which is worthy of promotion.…”
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326“…We found that patients with poor prognosis had higher mean serum levels of sLOX‐1 and Lp‐PLA2. The level of sLOX‐1 and Lp‐PLA2 could predict the functional outcome of ACI. …”
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327“…In Logistic regression analysis, MGP, Fetuin-A and Lp(a) were all independently associated with occurrence of CAVD (P<0.05). …”
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328por Ibrahim, Mahmoud A. A., Moussa, Nayra A. M., Saad, Sherif M. A., Ahmed, Muhammad Naeem, Shawky, Ahmed M., Soliman, Mahmoud E. S., Mekhemer, Gamal A. H., Rady, Al-shimaa S. M.“…[Image: see text] σ-Hole and lone-pair (lp)-hole interactions within σ-hole···σ-hole, σ-hole···lp-hole, and lp-hole···lp-hole configurations were comparatively investigated on the pnicogen···pnicogen homodimers (PCl(3))(2), for the first time, under field-free conditions and the influence of the external electric field (EEF). …”
Publicado 2022
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329por Zhang, Changliang, Zhang, Yu, Ma, Kai, Wang, Guangxian, Tang, Min, Wang, Runxin, Xia, Ziyue, Xu, Zhiyan, Sun, Miao, Bao, Xiaofeng, Gui, Hongxing, Wang, Hui“…Whole genome sequencing (WGS) of L. plantarum Lp3a was also performed. RESULTS: Lp3a-treated mice showed significantly improved intestinal motion, reduced time to first defecation, and increased stool amounts. …”
Publicado 2022
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333por Tang, Jia‐lin, Zhang, Bo, Xu, Jian‐ping, Qi, Ling, Xin, Dao, Wang, Lin, Wang, Bing‐zhi, Tian, Yan‐tao, Li, Yong, Huang, Jing“…We conducted a phase 1 trial to assess the safety and efficacy of LP002, an anti‐PD‐L1 antibody, plus chemotherapy as perioperative treatment in patients with gastric or GEJ cancer. …”
Publicado 2022
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334por Park, Junsun, Kim, Hyunmin, Gestaut, Daniel, Lim, Seyeon, Leitner, Alexander, Frydman, Judith, Roh, Soung-Hun“…Using cryoEM and biochemical analyses, we determine the ATP-driven cycle of TRiC-PFD-PhLP2A interaction. In the open TRiC state, PhLP2A binds to the chamber's equator while its N-terminal H3-domain binds to the apical domains of CCT3/4, thereby displacing PFD from TRiC. …”
Publicado 2023
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335por Samuvel, Devadoss J, Krishnasamy, Yasodha, Li, Li, Lemasters, John J, Chou, C James, Zhong, Zhi“…Here, we examined whether LP342, the lead candidate of a new generation of hydrazide-based HDAC inhibitors (HDACi), decreases hepatic IRI. …”
Publicado 2023
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338por Forte, Flavia Pilar, Malinowska, Marta, Nagy, Istvan, Schmid, Jan, Dijkwel, Paul, Hume, David E., Johnson, Richard D., Simpson, Wayne R., Asp, Torben“…In this study, we employed reduced representation bisulfite sequencing method (epiGBS) to investigate the impact of the Epichloë sp. LpTG-3 strain AR37 on the methylome of L. perenne across multiple grass generations and under drought stress conditions. …”
Publicado 2023
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340“…In this study, mouse MLN cells and thymocytes from advanced stages of LP(-)BM5 retrovirus infection were studied. A decrease in the percentage of IL-7(+) cells and an increase in the percentage of IL-16(+) cells in the MLN indicated that secretion of these cytokines was also altered after LP-BM5 infection. …”
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