“…The proportion of total regulatory T cells was not changed by IRT5 administration; however, the proportion of CCR9(+) regulatory T (Treg) cells expressing gut-homing receptor was significantly increased in pancreatic lymph nodes (PLNs) and lamina propria of the small intestine (SI-LP). Type 1 T helper (Th1) skewing was reduced in PLNs by IRT5 administration. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In this study, we used Lactobacillus plantarum HNU082 (Lp082) as a model probiotic to examine the impact of the continuous or pulsed supplementation of galactooligosaccharide (GOS) on the gut microbiome stability in mice using shotgun metagenomic sequencing. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Statistical analysis was performed using RevMan 5.3 (Cochrane, London, UK) and Stata 14.0 software (StataCorp LP, College Station, TX, USA). RESULTS: Eight studies involving 732 patients with HCC were included. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Use of this strategy to analyze purified subsets of normal human mammary cells showed that both the luminal progenitor-containing (LP) subset and the basal cells (BCs) display highly variable but overall similar autophagic flux activity despite differences suggested by measurements of the proteins responsible (i.e., LC3B, ATG7 and BECLIN1) in bulk lysates. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Further, we identify (V)LDL receptor LpR2, expressed in the BBB, as a host receptor for Blr, allowing GBS translocation through endocytosis. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…For comparison with the PUT safety results, conventional laser photocoagulation (LP) treatment was performed with standard clinical parameters: 532-nm continuous-wave (CW) laser with 0.1-second pulse duration, 450-mW power, and 75-µm spot size. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Lastly, we evaluated the effect of selective 5-HT7 receptor agonist LP-211 and antagonist (inverse agonist) SB-269970 on mitochondrial respiratory chain (MRC) cytochrome c oxidase activity on mitochondria from SH-SY5Y cells. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Compared with the HC group, the GM morphological networks of PKD patients showed significant abnormalities at the global level, including an increase in characteristic path length (Lp) and decreases in local efficiency (E (loc)), clustering coefficient (Cp), normalized clustering coefficient (γ), and small‐worldness (σ). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In this model, we used Mixed Integer Linear Programming (MILP) and Linear Programming (LP) optimization for different categories with different constraints for various loads. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This work aims to evaluate a probiotic combination of Lacticaseibacillus rhamnosus LR04 (DSM 16605), Lactiplantibacillus pentosus LPS01 (DSM 21980), Lactiplantibacillus plantarum LP01 (LMG P-21021), and Lactobacillus delbrueckii subsp. delbruekii LDD01 (DMS 22106), alone or together with other pharmacological therapies, for clinical improvement of symptoms associated with FD. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Lichen planus (L.P.) is a long-standing mucocutaneous inflammatory condition. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This interaction is dependent on the C-terminal EB homology region of EB1 and partially dependent on an SxLP motif of Arl4D. We found that Arl4D colocalized with γ-tubulin in centrosomes and the depletion of Arl4D resulted in a centrosomal MT nucleation defect. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Then, a hybrid solution approach is provided by combining the LP-metrics method with a heuristic algorithm. Furthermore, a real case study is investigated to evaluate the application of the model. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Here we show that a condensed benzo[b]thiazine derivative small molecule with an arylthiazine backbone (ADA-409-052) inhibits tert-Butyl hydroperoxide (TBHP)-induced lipid peroxidation (LP) and protects against ferroptotic cell death triggered by glutathione (GSH) depletion or glutathione peroxidase 4 (GPx4) inhibition in neuronal cell lines. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In this study, we tested the influence of four strains of E. festucae var. lolii (E+ (also known as Lp19), AR1, AR37, NEA2), and uninfected controls (E−), on L. perenne growth and the composition of root exudate metabolites. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Here, using the immunoprecipitation-mass spectrometry approach, we identify the flavodoxin-like protein (Fld-LP), CgPst2, to be an interactor of one of the aspartyl protease CgYps1. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…METHOD: Detailed structural and ultrastructural histopathological studies were performed on the kidneys of rats fed different amounts of fat and P: low (4%) fat (LF) and normal (0.6%) P (NP), LF and high (1.2%) P (HP), high (35%) fat (HF) and NP, HF and HP, and HF with low (0.2%) P (LP) for 28 weeks. RESULTS: Glomeruli of the HF groups showed segmental areas of retraction, sclerosis and thickening of the Bowman’s capsule and basal membranes, which were more accentuated in the HF–HP group. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Amphipathic α-helix bundles form a common motif that is shared between cytosolic LD binding proteins (e.g., perilipins 2, 3, and 5) and apolipoproteins, such as apoE and apoLp-III, found on lipoprotein particles. Here, we use pendant drop tensiometry to expand our previous work on the C-terminal α-helix bundle of perilipin 3 and the full-length protein. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In one proband, we identified a likely pathogenic (LP), de novo L1-mediated insertion in CDKL5 that results in duplication of exon 3, leading to a frameshift. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Analyses were conducted using Stata version 12.0 (StataCorp LP). RESULTS: A total of nine studies consisting of 1166 patients were included. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso