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7241por Kubben, Pieter L., Scholtes, Felix, Schijns, Olaf E.M.G., ter Laak-Poort, Mariël P., Teernstra, Onno P.M., Kessels, Alfons G. H., van Overbeeke, Jacobus J., Martin, Didier H., van Santbrink, HenkEnlace del recurso
Publicado 2014
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7242“…A series of serotonergic agonists established in their use of receptor characterization was tested, and the following rank order of potency found for agonist-induced relaxation (receptor selectivity): 5-CT (5-HT(1)/5-HT(7))>5-HT = LP-44 (5-HT(7))>PNU109291 (5-HT(1D)) = BW723C86 (5-HT(2B)). 8-OH-DPAT (5-HT(1A/7)), CP93129 (5-HT(1B)), mCPBG (5-HT(3/4)), AS19 (5-HT(7)) and TCB-2 (5-HT(2A)) did not relax the isolated vein. …”
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7243“…METHODS: We used two independent MM cell lines (RPMI 8226 and LP1) to generate several clones stably expressing either the green fluorescent protein (GFP) or a GFP-cyclin D1 fusion protein, and we analyzed the properties acquired following cyclin D1 expression. …”
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7244por Jain, Rajeev“…Results from ongoing CV outcome trials with other DPP-4 inhibitors may provide additional data on how best to manage patients with T2DM who are at risk for heart failure. FUNDING: AstraZeneca LP. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s12325-015-0262-9) contains supplementary material, which is available to authorized users.…”
Publicado 2015
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7245por Krantz, Mori J., Havranek, Edward P., Pereira, Rocio I., Beaty, Brenda, Mehler, Philip S., Long, Carlin S.“…Non-significant reductions in lipoprotein-associated phospholipase A2 (LpPLA2) mass and high sensitivity C-reactive protein (hsCRP) relative to placebo were also observed (p = 0.08, and 0.21, respectively). …”
Publicado 2015
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7246por Krauss, Scott, Stucker, Karla M, Schobel, Seth A, Danner, Angela, Friedman, Kimberly, Knowles, James P, Kayali, Ghazi, Niles, Lawrence J, Dey, Amanda D, Raven, Garnet, Pryor, Paul, Lin, Xudong, Das, Suman R, Stockwell, Timothy B, Wentworth, David E, Webster, Robert G“…Phylogenetic analysis of whole-genome sequences of the H7N3 influenza viruses from wild birds and HP H7N3 outbreaks in the Americas indicate that each HP outbreak was an independent emergence event and that the low pathogenic (LP) avian influenza precursors were most likely from dabbling ducks. …”
Publicado 2015
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7247“…Of total 4.5% had glaucoma, 3.3% macular degeneration and 21.7% had hypertension. 0.6% of population had macular degeneration, 0.4% of population had glaucoma Of 892 eyes (446 individuals), 36.2% had visual acuity less than 7/10, 1.7% light perception (LP) and 0.22% no light perception (NLP) and 2.7% finger count. …”
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7248“…During oral picture naming, activation in neurologically intact individuals is found in “classic” language regions involved with retrieval of lexical concepts [e.g., left middle temporal gyrus (LMTG)], word form encoding [e.g., left posterior superior temporal gyrus, (LpSTG)], and controlled retrieval of semantic and phonological information [e.g., left inferior frontal gyrus (LIFG)] as well as domain-general regions within the multiple demands network [e.g., left middle frontal gyrus (LMFG)]. …”
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7249“…Crude odds ratios (ORs) with 95% confidence intervals (CIs) were assessed for association using a random-effects or fixed-effects model using STATA version 10 (StataCorp LP, College Station, TX, USA). RESULTS: Overall, the analysis showed that carriers of APOE ε2 allele decreased risk for CHD (ε2 allele vs. ε3 allele: OR = 0.82, 95% CI: 0.75–0.90, P < 0.001; ε2 carriers vs. ε3 carriers: OR = 0.81, 95% CI: 0.73–0.89, P < 0.001), compared with those carrying ε3 allele, especially in Caucasian population. …”
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7250“…There were no differences in improvement of the visual analog scale back and leg pain (VAS-BP, VAS-LP) scores and Oswestry Disability Index (ODI) scores at 2 weeks, 3 months, 6 months, and 12 months after operation between the experimental and control groups. …”
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7251por Ferreira, Magda R. A., Fernandes, Mônica T. M., da Silva, Wliana A. V., Bezerra, Isabelle C. F., de Souza, Tatiane P., Pimentel, Maria F., Soares, Luiz A. L.“…BACKGROUND: Libidibia ferrea (Mart. ex Tul.) L.P. Queiroz (Fabaceae) is a tree which is native to Brazil, widely known as “Jucá,” where its herbal derivatives are used in folk medicine with several therapeutic properties. …”
Publicado 2016
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7252“…Compared to subjects without CHD, subjects with CHD were older, had higher frequencies of males and smokers, had higher heart rate, serum LDL cholesterol, Lp(a) and Hs-CRP levels. Percentages of subjects with hypertension, diabetes, gastrointestinal bleeding, and HP infection were also considerably higher in CHD group (P < 0.05 for all comparison). …”
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7253por Ortiz-Bustos, Carmen M., Pérez-Bueno, María L., Barón, Matilde, Molinero-Ruiz, Leire“…Significant differences between inoculated and control plants depended on the LP that was considered at any time. Measurements of Chl contents and final total Chl content supported the results of MCFI, but they were less sensitive in differentiating healthy from inoculated plants. …”
Publicado 2016
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7254“…Trabectedin (ET743, Yondelis(®), manufactured by Baxter Oncology GmbH, Halle/Westfalen, Germany, for Janssen Products, LP, Horsham, PA), derived from the marine ascidian, Ecteinascidia turbinata, is a natural alkaloid with multiple complex mechanisms of action. …”
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7255“…BACKGROUND: Mutations in the solute carrier family 22 member 3 (SLC22A3), lipoprotein (a)-like 2 (LPAL2), and the lipoprotein (a) (LPA) gene cluster, which encodes apolipoprotein (a) [apo (a)] of the lipoprotein (a) [Lp (a)] lipoprotein particle, have been suggested to contribute to the risk of coronary artery disease (CAD), but the precise variants of this gene cluster have not yet been identified in Chinese populations. …”
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7256por Rossell, Susan L., Francis, Paul S., Galletly, Cherrie, Harris, Anthony, Siskind, Dan, Berk, Michael, Bozaoglu, Kiymet, Dark, Frances, Dean, Olivia, Liu, Dennis, Meyer, Denny, Neill, Erica, Phillipou, Andrea, Sarris, Jerome, Castle, David J.“…Secondary outcome measures will include: changes in quality of life (QoL) as measured by the Lancashire Quality of Life Profile (LQoLP) and cognitive functioning as measured by the total score on the MATRICS. …”
Publicado 2016
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7257por Andrade, Ricardo, Wannagat, Martin, Klein, Cecilia C., Acuña, Vicente, Marchetti-Spaccamela, Alberto, Milreu, Paulo V., Stougie, Leen, Sagot, Marie-France“…CONCLUSIONS: The results show that the second approach efficiently enumerates minimal precursor sets taking stoichiometry into account, and allows for broad in silico studies of strains or species interactions that may help to understand e.g. pathotype and niche-specific metabolic capabilities. sasita is written in Java, uses cplex as LP solver and can be downloaded together with all networks and input files used in this paper at http://www.sasita.gforge.inria.fr. …”
Publicado 2016
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7258por Liu, Xiaowei, Li, Zhan, Wang, Xiaodong, Chen, Yujuan, Wu, Fengbo, Men, Ke, Xu, Ting, Luo, Yan, Yang, Li“…In this study, a new antibacterial peptide DP7-C (Chol-suc-VQWRIRVAVIRK-NH2) and DP7-C-modified azithromycin (AZT)-loaded liposomes (LPs) are developed for the treatment of MRSA infection, and it was found that DP7-C inserted into the LP lipid bilayer not only functioned as a carrier to encapsulate the antibiotic AZT but also synergized the antibacterial effect of the encapsulated AZT. …”
Publicado 2016
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7259“…Patients with non-dialysis-dependent CKD have low high-density lipoproteins (HDL), normal or low total cholesterol (TC) and low-density lipoprotein (LDL) cholesterol, increased triglycerides as well as increased apolipoprotein B (apoB), lipoprotein(a) (Lp (a)), intermediate- and very-low-density lipoprotein (IDL, VLDL; “remnant particles”), and small dense LDL particles. …”
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7260por Swe, Pearl M., Christian, Lindsay D., Lu, Hieng C., Sriprakash, Kadaba S., Fischer, Katja“…We investigated the relative role of classical (CP), lectin (LP) and alternative pathways (AP) towards a pyodermic GAS isolate 88/30 in the presence of a scabies mite complement inhibitor, SMSB4. …”
Publicado 2017
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