“…We wish to test the hypothesis that both autologous bone marrow expanded mesenchymal stem cells and autologous leukocyte-poor platelet-rich plasma (LP-PRP) implanted into the area of the disrupted tendinopathic patellar tendon will restore function, but tendon regeneration tissue will only be observed in the subjects treated with autologous bone marrow expanded mesenchymal stem cells. …”
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“…AVAILABILITY: The source code for this paper is available at: https://github.com/ruoqi-liu/LP-SDA.…”
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“…The results showed that MD of total cholesterol, triglyceride, LDL, VLDL, HDL, Lp(a), Apo A1, and Apo B levels in the patients compared with the controls were (MD = 13.74 mg/dl; 95% CI: 7.72–19.75; p< 0.00001), (MD = 26.04 mg/dl; 95% CI: 20.77–31.31; p< 0.00001), (MD = 11.41 mg/dl; 95% CI: 6.26–16.57; p< 0.0001), (MD = 4.82 mg/dl; 95% CI: 3.63–6.00; p< 0.00001), (MD = –2.78 mg/dl; 95% CI: –4.53 – –1.03; p< 0.002), (MD = 8.51 mg/dl; 95% CI: 4.86–12.17; p< 0.0001), (MD = –6.60 mg/dl; 95% CI: –13.96 – 0.75; p< 0.08), and (MD = 9.70 mg/dl; 95% CI: 3.02–16.39; p< 0.004), respectively. …”
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“…We found that blocking T cell homing increased colitis severity in the context of CTLA-4 blockade and that gut-trafficking blockade had different effects on different Th subsets and could facilitate the proliferation of Th17 cells in the lamina propria (LP). CONCLUSIONS: Our data reveals the fundamental mechanism underlying trafficking-blocking antibody therapy for CTLA-4 blockade-induced colitis and provide a caution in regard to apply trafficking-blocking antibody treatment under CTLA-4 blockade condition.…”
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“…Four EBV latency programs have been described with distinct sets of expressed proteins and viral RNAs: (1) Latency 0: EBER1 and EBER2 but no expression of proteins; (2) Latency 1 (true latency program): EBER1 and EBER2, EBNA1; (3) Latency 2 (default program): EBER1 and EBER2 and expression of EBNA1, latent membrane protein (LMP)-1, LMP2A, LMP2B; and (4) Latency 3 (growth program): EBER1 and EBER2 and expression of EBNA-leader protein (LP), EBNA 2–6, LMP1, LMP2A, LMP2B. The role of most EBV proteins has been characterized mainly in vitro using lymphoblastoid cell lines.…”
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“…Regarding the DMN, the posterior parietal cortex and lateral parietal (LP; R) were more strongly connected in the older group than in the younger group. …”
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“…Cumulative evidence suggests that MASP-2, and even other components of the LP, are largely redundant in human defenses and that individuals with MASP-2 deficiency do not seem to be particularly prone to infectious or autoimmune diseases.…”
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“…All NMR-HDL measures were correlated between themselves and with other HDL markers (HDL-C, apoA-I and LpA-I). In a multivariate model adjusted for cardiovascular risk factors and bioclinical variables, HDL-P and SHDL-P displayed the strongest inverse association with all-cause and cardiovascular mortality. …”
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“…Here we report that expression cloning followed by antigen screening identifies DNA-directed RNA polymerase beta’ (RpoC) from Moraxella catarrhalis as frequent antigen of BCRs of IgD(+) LP cells. Patients show predominance of HLA-DRB1*04/07 and the IgVH genes encode extraordinarily long CDR3s. …”
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“…RESULTS: Visual acuity on presentation included light perception (LP) in 18 eyes (29%) and hand motion (HM) in 23 eyes (37%). …”
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“…The plant height, RWC, TC, MI, LP, proline, Fv/Fm and Na/K ratio significantly reduced by salinity stress in pearl millet and both water and salinity stress in wheat. …”
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“…TREM1 siRNA knockdown in induced macrophages reduced their ability to promote migration and vascular mimicry in GBM cells in vitro, and treatment of mice with LP-17 peptide, which blocks TREM1, inhibited growth of GL261 orthotopic xenografts. …”
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“…Data analysis was conducted in R software version 3.4.2. and Stata version 12.0 (College Station, TX: Stata Corp LP). RESULTS: Ten studies including 963 cancer patients were selected as suitable for this study. …”
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“…As compared with un-transfected cells, transfected cells exhibited higher uptake of transferrin-modified liposomes (Tf-LP), which was due to the specific interaction between Tf and TfR overexpressed on the transfected cells. …”
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“…Results: In diabetes patients, B1B1 homozygotes of the CETP TaqIB polymorphism compared with B2 carriers (B1B2 + B2B2) had significantly lower diastolic blood pressure, apoB and apoB: apoA-1,and higher Lp(a) after the intake of sesame-canola oil, as well as lower insulin and HOMA-IR after the intake of sesame oil. …”
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“…Methods: Plasma total cholesterol, direct LDL-C, sdLDL-C, LDL-triglycerides (LDL-TG), high-density lipoprotein cholesterol (HDL-C), HDL2-C, HDL3-C, triglycerides, Lp(a), and adiponectin were measured in 2,030 men and women (median age 59 years, free of cardiovascular disease (CVD) and off cholesterol lowering medication). …”
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“…We find that PD-1 expression was high on T cells in polyps and lamina propria (LP) of Apc(Min/+) mice compared to polyp free (Apc+/+) littermates. …”
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“…ABSTRACT: Thirty Assaf male lambs (30 ± 1.9 kg of body weight) were allocated to three groups fed diets differing in their crude protein (CP) contents (low protein (LP), 134 g CP/kg dry matter (DM); medium protein (MP), 157 g CP/kg DM; and high protein (HP), 173 g CP/kg DM) to test the effect of dietary protein content on animal performance, rumen function, animal health, and carcass and meat quality. …”
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“…To reveal the involved mechanism, Ribo-zero RNA sequencing was employed to profile the lncRNA transcriptome in mammary tissue samples from yak at two physiological stages, namely lactation (LP) and dry period (DP). Notably, 1,599 lncRNA transcripts were identified through four rigorous steps and filtered through protein-coding ability. …”
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“…Each plant was infected with one of four strains of the endophyte: AR1, AR37, NEA2, and Lp19 (the “common strain”). We outcrossed the Alto mothers with pollen from a number of individuals from different ryegrass cultivars to create more genetic diversity in the hosts. …”
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