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541por Neamat-Allah, Ahmed N. F.“…AIM: Lumpy skin disease (LSD) is an infectious viral disease of cattle caused by LSD virus (LSDV) of the family Poxviridae characterized by skin nodules covering all parts of the body. …”
Publicado 2015
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542“…In this review, we provide an overview of LSD1 function in normal hematopoiesis and leukemia, and of the current clinical application of LSD1 inhibitors for the treatment of patients with AML.…”
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543por Smitheman, Kimberly N., Severson, Tesa M., Rajapurkar, Satyajit R., McCabe, Michael T., Karpinich, Natalie, Foley, James, Pappalardi, Melissa B., Hughes, Ashley, Halsey, Wendy, Thomas, Elizabeth, Traini, Christopher, Federowicz, Kelly E., Laraio, Jenny, Mobegi, Fredrick, Ferron-Brady, Geraldine, Prinjha, Rabinder K., Carpenter, Christopher L., Kruger, Ryan G., Wessels, Lodewyk, Mohammad, Helai P.“…The anti-tumor activity of GSK2879552 and GSK-LSD1, potent, selective irreversible inactivators of LSD1, has previously been described. …”
Publicado 2019
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544por Liu, Zhiyong, Yang, Li, Li, Longxue, Wei, Rongrui, Luo, Xiaoquan, Xu, Tingting, Huang, Yun, Mu, Zejing, He, Junwei“…On the contrary, LS and its four fractions can suppress the renin-angiotensin-aldosterone system (RAAS), including ADH arrest by LSB-H, LSB-L, LSC-L, LSD-L, and LSD-H and ALD arrest by LSD-L, as well as promote ANP release by LS-M, LSB-H, LSC-H, and LSD-H, while furosemide can suppress only arrest of ADH within 24 h compared with the control group. …”
Publicado 2019
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545por Binh, Tran Duy, Nguyen, Yen D. H., Pham, Tuan L. A., Komori, Kenichi, Nguyen, Thanh Q. C., Taninaka, Masahide, Kamei, Kaeko“…The function of LSD-2 as a regulator of lipolysis has also been demonstrated. …”
Publicado 2022
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546por Manea, Simona-Adriana, Vlad, Mihaela-Loredana, Lazar, Alexandra-Gela, Muresian, Horia, Simionescu, Maya, Manea, Adrian“…We hypothesize that lysine-specific demethylase 1A (LSD1/KDM1A) regulates key molecular effectors and pathways linked to atherosclerotic plaque formation. …”
Publicado 2022
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547por Hino, Shinjiro, Sakamoto, Akihisa, Nagaoka, Katsuya, Anan, Kotaro, Wang, Yuqing, Mimasu, Shinya, Umehara, Takashi, Yokoyama, Shigeyuki, Kosai, Ken-ichiro, Nakao, Mitsuyoshi“…The lysine-specific demethylase-1 (LSD1) is a unique nuclear protein that utilizes flavin adenosine dinucleotide (FAD) as a cofactor. …”
Publicado 2012
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548por Gasser, Peter, Holstein, Dominique, Michel, Yvonne, Doblin, Rick, Yazar-Klosinski, Berra, Passie, Torsten, Brenneisen, Rudolf“…The participants received either 200 μg of LSD (n = 8) or 20 μg of LSD with an open-label crossover to 200 μg of LSD after the initial blinded treatment was unmasked (n = 4). …”
Publicado 2014
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549“…Lysine-specific histone demethylase 1 (LSD1), also known as KDM1A, can remove the methyl group from lysine 4 and 9 at histone H3, which regulates transcriptional suppression and activation. …”
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550por Aerts, Laetitia, Haegeman, Andy, De Leeuw, Ilse, Philips, Wannes, Van Campe, Willem, Behaeghel, Isabelle, Mostin, Laurent, De Clercq, Kris“…Lumpy skin disease (LSD) diagnosis is primarily based on clinical surveillance complemented by PCR of lesion crusts or nodule biopsies. …”
Publicado 2021
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551por de Vasconcelos, Diego Protasio, Aidar, Felipe J., Lima, Tarcisio Brandao, Filho, Flavio Martins do Nascimento, Mendonça, Igor Leonardo Alves, Díaz-de-Durana, Alfonso López, Garrido, Nuno Domingos, Santiago, Michael Silveira, Junior, Walderi Monteiro da Silva“…There was a small (r < 0.3) and non-significant (p > 0.05) correlation in FPPAs between the LSD test and running in both groups. According to our results, DKV was not similar during the LSD test and running, and there was no significant correlation in FPPA values between the LSD test and running in both groups. …”
Publicado 2022
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552por Chen, Hsiao-Yun, Durmaz, Yavuz T., Li, Yixiang, Sabet, Amin H., Vajdi, Amir, Denize, Thomas, Walton, Emily, Laimon, Yasmin Nabil, Doench, John G., Mahadevan, Navin R., Losman, Julie-Aurore, Barbie, David A., Tolstorukov, Michael Y., Rudin, Charles M., Sen, Triparna, Signoretti, Sabina, Oser, Matthew G.“…Some small cell lung cancers (SCLCs) are highly sensitive to inhibitors of the histone demethylase LSD1. LSD1 inhibitors are thought to induce their anti-proliferative effects by blocking neuroendocrine differentiation, but the mechanisms by which LSD1 controls the SCLC neuroendocrine phenotype are not well understood. …”
Publicado 2022
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553por El Mansouri, Fatima Ezzahra, Nebbaki, Salwa-Sarah, Kapoor, Mohit, Afif, Hassan, Martel-Pelletier, Johanne, Pelletier, Jean-Pierre, Benderdour, Mohamed, Fahmi, Hassan“…The LSD1 level in cartilage was determined by RT-PCR and immunohistochemistry. …”
Publicado 2014
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554por Ochwo, Sylvester, VanderWaal, Kimberly, Munsey, Anna, Ndekezi, Christian, Mwebe, Robert, Okurut, Anna Rose Ademun, Nantima, Noelina, Mwiine, Frank Norbert“…BACKGROUND: Lumpy skin disease (LSD) is a devastating transboundary viral disease of cattle which causes significant loss in production. …”
Publicado 2018
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555por Novakovic, Daniel, Sheth, Meet, Stewart, Thomas, Sandham, Katrina, Madill, Catherine, Chacon, Antonia, Nguyen, Duy Duong“…Laryngeal sensory dysfunction (LSD) encompasses disorders of the vagal sensory pathways. …”
Publicado 2021
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556“…In this review, we compiled what is known about the LSD1 function in various sarcomas, to determine where knowledge is lacking and to find what theme emerge to characterize how LSD1 is a key molecular driver in bone and soft tissue sarcoma. …”
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557por Kumar, SG Prem, Ranpise, Dhanaji, Vishwakarma, Pankaj, Gend, Pravin B, Chavan, Shobhana, Kurian, Elizabeth“…Interviews were performed using standardized scales to assess ES, LSD, and SE. Variations in the intensity of ES, LSD, and SE were assessed using multiple classification analysis (MCA). …”
Publicado 2023
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558“…Interestingly, miR-137 was increased and its target genes Lsd1 and Lsd1 + 8a were decreased in the AIE adult amygdala. …”
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559por Calistri, Paolo, DeClercq, Kris, De Vleeschauwer, Annebel, Gubbins, Simon, Klement, Eyal, Stegeman, Arjan, Cortiñas Abrahantes, José, Antoniou, Sotiria‐Eleni, Broglia, Alessandro, Gogin, Andrey“…The duration of the vaccination campaign sufficient to eliminate lumpy skin disease (LSD) mainly depends on the vaccination effectiveness and coverage achieved. …”
Publicado 2018
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560por Calistri, Paolo, De Clercq, Kris, Gubbins, Simon, Klement, Eyal, Stegeman, Arjan, Cortiñas Abrahantes, José, Marojevic, Drago, Antoniou, Sotiria‐Eleni, Broglia, Alessandro“…In 2019, no lumpy skin disease (LSD) outbreaks were reported in South‐Eastern Europe, the mass vaccination regional campaign with homologous LSD vaccine continued for the fourth year with over 1.8 million bovines vaccinated in the region, preventing further outbreaks since 2016. …”
Publicado 2020
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