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Mostrando 41 - 60 Resultados de 1,917 Para Buscar '"LSD"', tiempo de consulta: 0.18s Limitar resultados
  1. 41
    “…Lysergic acid diethylamide (LSD) is a potent hallucinogenic drug affecting the mood and perception of an individual. …”
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    Suicidal cut‐throat wound during LSD intoxication
  2. 42
    “…In this review, we summarize current knowledge about LSD1 and the molecular mechanism by which LSD1 influences the stem cells state, including the regulatory circuitry underlying self-renewal and pluripotency.…”
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    LSD1: Expanding Functions in Stem Cells and Differentiation
  3. 43
    “…LSD administrations were matched to dose groups according to measured LSD peak plasma concentrations to adjust for uncertainties in the correct LSD dose in some studies. …”
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    Safety pharmacology of acute LSD administration in healthy subjects
  4. 44
    “…Pharmacological inhibition of LSD1 has shown promising therapeutic benefits for AD treatment. …”
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    Biological and therapeutic role of LSD1 in Alzheimer’s diseases
  5. 45
    “…PURPOSE: Many analogs of lysergic acid diethylamide (LSD) have recently appeared as designer drugs around the world. …”
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    Identification of LSD analogs, 1cP-AL-LAD, 1cP-MIPLA, 1V-LSD and LSZ in sheet products
  6. 46
    “…BACKGROUND: Genetic studies of the Arabidopsis mutant lsd1 highlight the important role of LSD1 in the negative regulation of plant programmed cell death (PCD). …”
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    The LSD1-Type Zinc Finger Motifs of Pisum sativa LSD1 Are a Novel Nuclear Localization Signal and Interact with Importin Alpha
  7. 47
    “…This review focuses on recent advances in LSD1 and tumor immunity and discusses a potential therapeutic strategy for combining LSD1 inhibition with immunotherapy.…”
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    Targeting LSD1 in tumor immunotherapy: rationale, challenges and potential
  8. 48
    “…Lysergic acid diethylamide (LSD) is a potent classic serotonergic psychedelic, which facilitates a variety of altered states of consciousness. …”
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    Dose-response relationships of LSD-induced subjective experiences in humans
  9. 49
    “…BACKGROUND: The non-selective serotonin 2A (5-HT(2A)) receptor agonist lysergic acid diethylamide (LSD) holds promise as a treatment for some psychiatric disorders. …”
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    Effect of lysergic acid diethylamide (LSD) on reinforcement learning in humans
  10. 50
    por Carstairs, Catherine
    Publicado 2010
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    Book Reviews: Psychedelic psychiatry: LSD from clinic to campus
  11. 51
    “…Here we show that these stimuli increase the levels of lysine-specific demethylase 1 (LSD1) in WAT of mice and that elevated LSD1 levels induce mitochondrial activity. …”
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    LSD1 promotes oxidative metabolism of white adipose tissue
  12. 52
    “…METHODS: LSD1 inhibitors were examined for their biochemical and biological activities against LSD1 and MLL-rearranged leukemia as well as other cancer cells. …”
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    Pharmacological inhibition of LSD1 for the treatment of MLL-rearranged leukemia
  13. 53
    “…LSD is an ambiguous substance, said to mimic psychosis and to improve mental health in people suffering from anxiety and depression. …”
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    Altered network hub connectivity after acute LSD administration
  14. 54
    “…As such, the purpose of this study was to determine the role of LSD2 in the epigenetic regulation of Ewing sarcoma, characterize genes regulated by LSD2, and examine the impact of SP-2509 drug treatment on LSD2 gene regulation. …”
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    Investigating the role of LSD2 as an epigenetic regulator in Ewing sarcoma
  15. 55
    “…Though LSD1 is implicated in heterochromatin regulation, its function is inconsistent across different systems; orthologs of LSD1 have been shown to either promote or antagonize heterochromatin expansion by removing H3K4me or H3K9me respectively. …”
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    LSD1 prevents aberrant heterochromatin formation in Neurospora crassa
  16. 56
    “…Lysine-specific histone demethylase 1 (LSD1) represents the first example of an identified nuclear protein with histone demethylase activity. …”
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    LSD1: more than demethylation of histone lysine residues
  17. 57
    “…In addition, no individual traits which would make the patient particularly susceptible to adverse LSD effects have subsequently been identified. This suggests that LSD may confer toxic effects in previously healthy individuals.…”
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    Severe Neurological Sequelae after a Recreational Dose of LSD
  18. 58
    “…As selective inhibitors of LSD1 are being exploited as potential cancer therapeutics, our study supports the importance of leveraging an appropriate level of LSD1 to curb the side effects of anti-LSD1 therapy.…”
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    LSD1 is required for euchromatic origin firing and replication timing
  19. 59
    “…RATIONALE: LSD is the prototypical psychedelic. Despite a clear central role of the 5HT(2a) receptor in its mechanism of action, the contributions of additional receptors for which it shows affinity and agonist activity remain unclear. …”
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    Differential contributions of serotonergic and dopaminergic functional connectivity to the phenomenology of LSD
  20. 60
    “…Multiple components of the epigenetically repressive lysine-specific demethylase 1 (LSD1)/nucleosome remodeling and histone deacetylase (NuRD) complex, most notably LSD1 and histone deacetylase 2 (HDAC2), were found to be associated with Prox1 and GST pulldown assay demonstrated that Prox1 directly interacts with LSD1. …”
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    Prox1 Directly Interacts with LSD1 and Recruits the LSD1/NuRD Complex to Epigenetically Co-Repress CYP7A1 Transcription
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