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861por Cavalera, Simone, Pezzoni, Giulia, Grazioli, Santina, Brocchi, Emiliana, Baselli, Stefano, Lelli, Davide, Colitti, Barbara, Serra, Thea, Nardo, Fabio Di, Chiarello, Matteo, Testa, Valentina, Rosati, Sergio, Baggiani, Claudio, Anfossi, Laura“…Lumpy skin disease (LSD) is an infectious disease affecting bovine with severe symptomatology. …”
Publicado 2022
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862por Hecker, Dietmar J., Scherer, Hans, Schönfeld, Uwe, Jerono, Laura, Koch, Armand, Rink, Anna-Katharina, Schulte-Goebel, Lisa, Linxweiler, Maximilian, Fousse, Mathias, Bozzato, Alessandro, Schick, Bernhard“…The new value of late shift difference (LSD) was 0.01 ms. The test retest-reliability showed good to excellent ICC results in 9 out of 10 measurements. …”
Publicado 2022
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863por Vélez Pinos, Paola Jacqueline, Saavedra Palacios, Michell Susan, Colina Arteaga, Paolo Andrés, Arevalo Cordova, Tania Diciana“…Niemann-Pick disease (NPD) A/B is a lysosomal storage disease (LSD), caused by an autosomal recessive disorder that causes variation in sphingomyelin phosphodiesterase-1 (SMPD1). …”
Publicado 2023
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864por Zhang, Tejia, Alonzo, Ivy, Stubben, Chris, Geng, Yijie, Herdman, Chelsea, Chandler, Nancy, Doane, Kim P., Pluimer, Brock R., Trauger, Sunia A., Peterson, Randall T.“…Given the role of myelin loss as a major contributor toward LSD-associated neurodegeneration, we investigated the pathways contributing to demyelination in a CRISPR-Cas9-generated zebrafish model of combined saposin (psap) deficiency. psap knockout (KO) zebrafish recapitulated major LSD pathologies, including reduced lifespan, reduced lipid storage, impaired locomotion and severe myelin loss; loss of myelin basic protein a (mbpa) mRNA was progressive, with no changes in additional markers of oligodendrocyte differentiation. …”
Publicado 2023
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865“…We used recent data from the National Survey on Drug Use and Health (2015–2020) and multivariable logistic regression to test the relationships that lifetime use of seven individual hallucinogens (MDMA/ecstasy, PCP, ketamine, psilocybin, LSD, peyote, and mescaline) shares with hallucinogen dependence and abuse among individuals who initiated hallucinogen use within the past two years (N = 5,252). …”
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866por Poupětová, Helena, Ledvinová, Jana, Berná, Linda, Dvořáková, Lenka, Kožich, Viktor, Elleder, Milan“…Gaucher disease was the most frequent LSD with a birth prevalence of 1.13 per 100,000 births. …”
Publicado 2010
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867por Wang, Quan, Xu, Xinxiu, Li, Jun, Liu, Jing, Gu, Haifeng, Zhang, Ru, Chen, Jiekai, Kuang, Yin, Fei, Jian, Jiang, Cong, Wang, Ping, Pei, Duanqing, Ding, Sheng, Xie, Xin“…We also found that Li exerts its effect by promoting epigenetic modifications via downregulation of LSD1, a H3K4-specific histone demethylase. Knocking down LSD1 partially mimics Li's effect in enhancing reprogramming. …”
Publicado 2011
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868“…To gain insight into abnormal functions occurring secondary to a single gene defect, whole transcriptome analysis was used to identify molecular and cellular pathways that are dysregulated in the brain in a mouse model of a lysosomal storage disorder (LSD) (mucopolysaccharidosis [MPS] VII). We assayed multiple anatomical regions separately, in a large cohort of normal and diseased mice, which greatly increased the number of significant changes that could be detected compared to past studies in LSD models. …”
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869por Altarescu, Gheona, Beeri, Rachel, Eiges, Rachel, Epsztejn-Litman, Silvina, Eldar-Geva, Talia, Elstein, Deborah, Zimran, Ari, Margalioth, Ehud J., Levy-Lahad, Ephrat, Renbaum, Paul“…We present the strategy and outcome of PGD for four lysosomal storage disorders (LSD): Tay-Sachs disease (TSD), Gaucher disease (GD), Fabry disease (FD), and Hunter syndrome (HS), and subsequent development of stem cell lines. …”
Publicado 2012
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870por Andrisani, Ourania M.“…Znf198, stabilizes the LSD1-CoREST-HDAC complex that removes, via lysine demethylase1 (LSD1), the activating trimethylation of H3 on lysine-4 (H3K4me3). …”
Publicado 2013
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871por Lv, Longwei, Ge, Wenshu, Liu, Yunsong, Lai, Guanyou, Liu, Hao, Li, Wenyue, Zhou, Yongsheng“…Here, we investigated pargyline, an inhibitor of lysine-specific demethylase 1 (LSD1), which mainly catalyzes the demethylation of the di- and mono-methylation of H3K4. …”
Publicado 2016
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872por Torres, Sandra, Balboa, Elisa, Zanlungo, Silvana, Enrich, Carlos, Garcia-Ruiz, Carmen, Fernandez-Checa, Jose C.“…Lysosomal storage disorders (LSD) are characterized by the accumulation of diverse lipid species in lysosomes. …”
Publicado 2017
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873por Sprygin, Alexander, Babin, Yurii, Pestova, Yana, Kononova, Svetlana, Wallace, David B., Van Schalkwyk, Antoinette, Byadovskaya, Olga, Diev, Vyacheslav, Lozovoy, Dmitry, Kononov, Alexander“…These findings provide evidence for the first time of genetic exchanges between closely related strains of capripoxviruses in the field and a vaccine strain, and prompt a revisiting of the vaccination issue for a safe and efficacious prevention and control strategy of LSD.…”
Publicado 2018
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874por Casal, Jordi, Saegerman, Claude, Bertagnoli, Stéphane, Meyer, Gilles, Ganière, Jean Pierre, Caufour, Philippe, De Clercq, Kris, Jacquiet, Philippe, Hautefeuille, Claire, Etore, Florence, Napp, Sebastián“…Assuming a 7-weeks period to vaccinate all the animals and a spread of the disease of 7.3 km/week, the vaccination of 740 716 cattle would be enough to control an epidemic of LSD in France in 90% of the simulations (608 196 cattle would cover 75% of the simulations). …”
Publicado 2019
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875por Feng, Yaling, Wang, Jianxia, He, Yue, Zhang, Heng, Jiang, Minhui, Cao, Dandan, Wang, Aiping“…Chromatin immunoprecipitation assays determined that DIAPH2-AS1 recruited LSD1 to histone 3, increasing DNMT1 stability at H3. …”
Publicado 2019
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876“…However, evidence showing that classic or serotonergic hallucinogens/psychedelics such as psilocybin and lysergic acid diethylamide (LSD) could be effective treatments for depressive and anxiety disorders in end-stage cancer was not included. …”
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877por Sohier, C., Haegeman, A., Mostin, L., De Leeuw, I., Campe, W. Van, De Vleeschauwer, A., Tuppurainen, E. S. M., van den Berg, T., De Regge, N., De Clercq, K.“…Lumpy skin disease (LSD) is a devastating disease of cattle characterized by fever, nodules on the skin, lymphadenopathy and milk drop. …”
Publicado 2019
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878por Subramaniyan, Boopathi, Sridharan, Sangita, M. Howard, Cory, M.C. Tilley, Augustus, Basuroy, Tupa, de la Serna, Ivana, Butt, Elke, Raman, Dayanidhi“…The CXCR4-LASP1 axis may directly regulate the stabilization of nuclear Snail1, by upregulating nuclear levels of pS473-Akt, pS9-GSK-3β, A20, and LSD1. Furthermore, the activation of CXCR4 induced association of LASP1 with Snail1, A20, GSK-3β, and LSD1 endogenously. …”
Publicado 2020
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879por Zheng, Lian, Guan, Zhen-Jie, Pan, Wen-Ting, Du, Tian-Feng, Zhai, Yu-Jia, Guo, Jia“…Furthermore, we identified that LSD1 could epigenetically activate TP53 by recruiting H3K27me1 and H3K4m2 to its promoter. …”
Publicado 2018
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880por Bamouh, Zahra, Hamdi, Jihane, Fellahi, Siham, Khayi, Slimane, Jazouli, Mohammed, Tadlaoui, Khalid Omari, Fihri, Ouafaa Fassi, Tuppurainen, Eeva, Elharrak, Mehdi“…The aim of this work was to compare the safety of two lumpy skin disease (LSD) vaccine strains, Kenyan (Kn) Sheep and Goat Pox (KSGP O-240) and LSDV Neethling (Nt) strain, and to determine the etiology of the post-vaccination (pv) reactions observed in cattle. …”
Publicado 2021
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