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Abuso de drogas
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1041“…The goal of this review is to summarize the neurodegenerative murine LSD models available that recapitulate human disease, and the pre-clinical studies previously conducted. …”
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1042por Issimov, Arman, Taylor, David B., Shalmenov, Malik, Nurgaliyev, Birzhan, Zhubantayev, Izimgali, Abekeshev, Nurzhan, Kushaliyev, Kaissar, Kereyev, Abzal, Kutumbetov, Lespek, Zhanabayev, Assylbek, Zhakiyanova, Yasmin, White, Peter J.“…Lumpy skin disease (LSD) is an emerging disease of cattle in Kazakhstan and the means of transmission remains uncertain. …”
Publicado 2021
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1043“…Genetic analyses have revealed further examples, notably GRN, TREM2, EIF2AK3, and several other LSD and mitochondria function genes. In this Review, we discuss the evidence supporting the strikingly distinct allele-dependent clinical phenotypes observed in carriers of such gene mutations and its impact on the wider field of neurodegeneration.…”
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1044por Vidanović, Dejan, Tešović, Bojana, Šekler, Milanko, Debeljak, Zoran, Vasković, Nikola, Matović, Kazimir, Koltsov, Andrey, Krstevski, Kiril, Petrović, Tamaš, De Leeuw, Ilse, Haegeman, Andy“…Lumpy skin disease (LSD) is an important animal disease with significant health and economic impacts. …”
Publicado 2021
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1045“…Aiming at the automatic registration problem of multi-angle optical images for ground scenes, a registration method combining point features and line features to register images is proposed. Firstly, the LSD (Line Segment Detector) algorithm is used to extract line features of images. …”
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1046por Oster, Ena, Čudina, Nikola, Pavasović, Hrvoje, Prevendar Crnić, Andreja, Božić, Frane, Fadel, Charbel, Giorgi, Mario“…In this paper we gathered information about the most common recreational drugs such as amphetamines, methamphetamine, 3,4-methylenedioxy-methamphetamine (MDMA), phencyclidine (PCP), lysergic acid diethylamide (LSD), psilocybin mushrooms and cocaine in terms of toxicokinetic properties, mechanism of toxic action, clinical presentation and treatment in dogs and cats.…”
Publicado 2023
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1047“…Finally, we find that lysine-specific demethylase 1 (LSD1) interacts with PRC2 and contributes to the H3K27me3-H3K4me1 transition in mESCs. …”
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1048por Bonny-Noach, Hagit, Shapira, Barak, Baumol, Pinchas, Tadmor, Nir, Rosca, Paola, Shoshan, Stacy, Harel-Fisch, Yossi, Caduri, Ariel“…RESULTS: The most common illicit substances used at Israeli nature rave parties in the past year were cannabis (62.2%), followed by LSD (41.4%), MDMA (31.7%), mushrooms/psilocybin (23.9%), ketamine (19.6%) and cocaine (17.2%). …”
Publicado 2023
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1049por Hennermann, Julia B., Raebel, Eva M., Donà, Francesca, Jacquemont, Marie-Line, Cefalo, Graziella, Ballabeni, Andrea, Malm, Dag“…BACKGROUND: Alpha-mannosidosis is a rare autosomal recessive lysosomal storage disorder (LSD) caused by reduced activity of alpha-mannosidase. …”
Publicado 2022
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1050“…It is well understood that usage of psychedelics/hallucinogens, such as lysergic acid diethylamide (LSD), ecstasy, phencyclidine (PCP), and psilocybin-containing mushrooms, has increased significantly over the last few decades, particularly in adolescents and young adults, yet the effects of these recreational drugs are poorly understood. …”
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1051por Kuypers, K. P.“…ABSTRACT: Decades ago, the classical psychedelics psilocybin and LSD entered the therapeutic setting and already then showed their therapeutic potential in the treatment of psychiatric disorders. …”
Publicado 2023
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1052“…Hallucinations may follow consumption of LSD, amphetamines, or cocaine. MDMA is a major cause of acute severe hyponatraemia and also has been linked with hepatic syndromes. …”
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1053“…RESULTS: A repeated measures multivariate analysis of variance (RMANOVA) with LSD post-hoc tests were used to analyze the data. …”
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1054“…Gaucher disease (GD), the most common lysosomal storage disorder (LSD), is caused by the defective activity of the lysosomal hydrolase glucocerebrosidase, which is encoded by the GBA gene. …”
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1055“…The results of multiple one way repeated measures ANOVAs and post hoc LSD tests demonstrated that the moving direction had effects on average velocity, movement time, movement unit and peak velocity. …”
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1056por Hadianfard, Habib“…Descriptive statistics, one-way multivariate analysis of variance (MANOVA) and Least Significant Difference (LSD) was performed by using SPSS software. Result: The result of the research showed that almost 60% of participants had experienced neglect and 35% psychological abuse. …”
Publicado 2014
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1057“…Analysis of the data involved analysis of covariance (ANCOVA) with the Fisher's Least Significant Difference (LSD) as post-hoc test plus the Pearson correlation. …”
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1058“…In this review, we describe those enzymes and their inhibitors that have already reached the first stages of clinical trials in cancer therapy, namely the histone methyltransferases DOT1L and EZH2 as well as the demethylase LSD1.…”
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1059por Piao, Lianhua, Nakakido, Makoto, Suzuki, Takehiro, Dohmae, Naoshi, Nakamura, Yusuke, Hamamoto, Ryuji“…Automethylation of SUV39H2 led to impairment of its binding affinity to substrate proteins such as histone H3 and LSD1. Furthermore, we observed that hyper-automethylated SUV39H2 reduced methylation activities to substrates through affecting the binding affinity to substrate proteins. …”
Publicado 2016
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1060“…Besides, we also uncovered that FEZF1-AS1 could suppress p57 expression through recruiting EZH2 and LSD1 to the promoter of p57, thus influenced the cell cycle and proliferation. …”
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