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Abuso de drogas
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1161por Al-Hemoud, Ali, AlSaraf, Manar, Malak, Mariam, Al-Shatti, Musab, Al-Jarba, Meshael, Othman, Ahmad, Al-Shammari, Hanadi, Al-Shatti, Alya“…Five animal diseases were identified in Kuwait; namely, HPAI, FMD, glanders, LSD and MERS-CoV. The highest numbers of outbreaks were recorded for HPAI, followed by FMD. …”
Publicado 2021
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1162“…Statistical analyses, ANOVA analysis, and multiple comparisons (with least significant difference, LSD) were applied to the collected data. It has been found that boys and girls have similar self-efficacy of adolescent sports health. …”
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1163por Daher, René, Krejci, Ivo, Mekki, Mustapha, Marin, Charlotte, Di Bella, Enrico, Ardu, Stefano“…Results: Bond-strength values ranged from 8.2 MPa for 15 s etched unground enamel with primer application to 19.6 MPa for 30 s etched ground enamel without primer application. ANOVA and Fisher’s LSD post hoc tests revealed significant differences between the groups. …”
Publicado 2021
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1164por Zhou, Zhuolong, Van der Jeught, Kevin, Fang, Yuanzhang, Yu, Tao, Li, Yujing, Ao, Zheng, Liu, Sheng, Zhang, Lu, Yang, Yang, Eyvani, Haniyeh, Cox, Mary L., Wang, Xiyu, He, Xiaoming, Ji, Guang, Schneider, Bryan P., Guo, Feng, Wan, Jun, Zhang, Xinna, Lu, Xiongbin“…We show that the epigenetic inhibitors GSK-LSD1, CUDC-101 and BML-210, identified by the screen, display antitumour activities in orthotopic mammary tumours in mice, that they upregulate antigen presentation mediated by the major histocompatibility complex class I on breast tumour cells, and that treatment with BML-210 substantially sensitized breast tumours to the checkpoint inhibitor programmed-death-1. …”
Publicado 2021
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1165“…The objective of this study was to validate a new ultra-high performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS) method for quantification of six R and six S-epimers of ergot alkaloids in hard red spring wheat utilizing deuterated lysergic acid diethylamide (LSD-D(3)) as an internal standard. Validation parameters such as linearity, limit of detection (LOD), limit of quantification (LOQ), matrix effects, recovery and precision were investigated. …”
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1166“…Niemann-Pick disease (NPD) is a rare lysosomal storage disease (LSD) with multisystemic involvement. The disease is heterogeneous and classified into three subtypes: type A and B result from deficient acid sphingomyelinase activity and leads to the accumulation of sphingomyelin and type C is a genetically different disease resulting from defective intracellular trafficking of cholesterol with accumulation of glycosphingolipids. …”
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1167“…In this review, we introduce the roles of epigenetic modifiers, focusing on LSD1, BMI1, G9a, and SETDB1, in contributing to CSC characteristics and discussing the interplay between CSCs and interferon response. …”
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1168“…The elderly present with progressive degenerative osteoarthritis of the knee and lumbar spine degeneration (LSD). The coexistent conditions when presented concurrently become challenging for the clinicians and surgeons, as well as determining the predominant source of the underlying pain generation factor. …”
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1169por Liu, Yingmeng, Zhang, Shiming, Sakran, Karim Ahmed, Yin, Jiayi, Lan, Min, Yang, Chao, Wang, Yan, Zeng, Ni, Huang, Hanyao, Shi, Bing“…One-way ANOVA with least significant difference (LSD) post-test was used to evaluate the statistical significance. …”
Publicado 2022
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1170por Xiao, Changrui, Koziura, Mary, Cope, Heidi, Spillman, Rebecca, Tan, Khoon, Hisama, Fuki M., Tifft, Cynthia J., Toro, Camilo“…OBJECTIVES: To review the referral and clinical characteristics of adult patients diagnosed with lysosomal storage diseases (LSD) through the Undiagnosed Diseases Network (UDN). …”
Publicado 2022
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1171“…Transcriptional levels of key genes associated with glycolipid metabolism were further evaluated, including dilp, InR, and downstream dAKT-dFOXO-PEPCK, together with E78, SREBP, FAS, and LSD genes, were all downregulated after BLPs-exposure, suggesting the ameliorative effect of BLPs on dysbiosis associated with the insulin signaling pathway. …”
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1172por Ao, Zheng, Cai, Hongwei, Wu, Zhuhao, Hu, Liya, Nunez, Asael, Zhou, Zhuolong, Liu, Hongcheng, Bondesson, Maria, Lu, Xiongbin, Lu, Xin, Dao, Ming, Guo, Feng“…By screening a drug library using this technology, we identified an epigenetic drug (lysine-specific histone demethylase 1 inhibitor, LSD1i) that effectively promoted T cell tumor infiltration and enhanced treatment efficacy in combination with an immune checkpoint inhibitor (anti-PD1) in vivo. …”
Publicado 2022
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1173por Haegeman, Andy, De Leeuw, Ilse, Mostin, Laurent, Van Campe, Willem, Philips, Wannes, Elharrak, Mehdi, De Regge, Nick, De Clercq, Kris“…Vaccines have proven themselves as an efficient way to control and eradicate lumpy skin disease (LSD). In addition to the safety and efficacy aspects, it is important to know the duration for which the vaccines confer protective immunity, as this impacts the design of an efficient control and eradication program. …”
Publicado 2023
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1174“…Earlier, we discovered such properties of the stem cell–supporting small molecule UM171 and identified that members of the CoREST complex (RCOR1 and LSD1) are targeted for degradation. UM171 supports the in vitro propagation of hematopoietic stem cells by transiently perturbing the differentiation-promoting effects of CoREST. …”
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1175por Bernacki, Maciej Jerzy, Mielecki, Jakub, Antczak, Andrzej, Drożdżek, Michał, Witoń, Damian, Dąbrowska-Bronk, Joanna, Gawroński, Piotr, Burdiak, Paweł, Marchwicka, Monika, Rusaczonek, Anna, Dąbkowska-Susfał, Katarzyna, Strobel, Wacław Roman, Mellerowicz, Ewa J., Zawadzki, Janusz, Szechyńska-Hebda, Magdalena, Karpiński, Stanisław“…The cell death regulatory genes, LESION SIMULATING DISEASE 1 (LSD1), PHYTOALEXIN DEFICIENT 4 (PAD4) and ENHANCED DISEASE SUSCEPTIBILITY 1 (EDS1) conditionally regulate the cell wall when suppressed in transgenic aspen. …”
Publicado 2023
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1176“…Dates were compared using analysis of variance (ANOVA) and the least significant difference (LSD) test. Furthermore, optical microscopy and scanning electron microscopy (SEM) were used to examine the failure modes and observe the cross-sectional structures, respectively. …”
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1177por Luque-Vilca, Olivia Magaly, Pampa-Quispe, Noe Benjamin, Pumacahua-Ramos, Augusto, Pilco-Quesada, Silvia, Cabel Moscoso, Domingo Jesús, Choque-Rivera, Tania Jakeline“…The proximal composition, amylose content, and morphological, thermal, and rheological properties that SEM, DSC, and a rheometer determined, respectively, were evaluated, and the data obtained were statistically analyzed using a completely randomized design and then a comparison of means using Tukey’s LSD test. The results show a significant difference in the proximal composition (p ≤ 0.05) concerning moisture content, proteins, fat, ash, and carbohydrates. …”
Publicado 2023
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1178“…LSDs were diagnosed in 74/248 patients (30%), and mucopolysaccharidosis was the most frequently observed LSD (28/74; 38%). CONCLUSION: We believe that our data underestimate the true incidence of IEM in the region. …”
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1179por Arabaci, Taner, Cicek, Yasin, Canakci, Varol, Canakci, Cenk Fatih, Ozgoz, Mehmet, Albayrak, Mevlut, Keles, Osman Nuri“…A one-way analysis of variance (ANOVA) and a multiple range least significant difference (LSD) were used for intergroup comparisons (P=0.05). …”
Publicado 2010
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1180“…Multivariate analysis (generalized Procrustes analysis, Mahalanobis distances, multivariate regression) and complementary dimensions of size were evaluated with ANOVA and post hoc LSD. Results suggest that important cranial shape differentiation does occur between pygmies and non-pygmies but also between Eastern and Western populations and that size changes and allometries do not affect similarly Eastern and Western pygmies. …”
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