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Abuso de drogas
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1781por Vallersnes, Odd Martin, Dines, Alison M., Wood, David M., Yates, Christopher, Heyerdahl, Fridtjof, Hovda, Knut Erik, Giraudon, Isabelle, Dargan, Paul I.“…Psychosis was frequent in those ED presentations involving tryptamines (4/7; 57.1 %), methylenedioxypyrovalerone (MDPV) (6/22; 27.3 %), methylphenidate (6/26; 23.1 %), lysergic acid diethylamide (LSD) (18/86; 20.9 %), psilocybe mushrooms (3/16; 18.8 %), synthetic cannabinoid receptor agonists (4/26; 15.4 %) and amphetamine (87/593; 14.7 %), but less common in those involving mephedrone (14/245; 5.7 %), methylenedioxymethamphetamine (MDMA) (20/461; 4.3 %) and methedrone (3/92; 3.3 %). …”
Publicado 2016
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1782por Pinkerneil, Maria, Hoffmann, Michèle J., Kohlhof, Hella, Schulz, Wolfgang A., Niegisch, Günter“…Class I HDACs are often deregulated in urothelial cancer. 4SC-202, a novel oral benzamide type HDAC inhibitor (HDACi) specific for class I HDACs HDAC1, HDAC2 and HDAC3 and the histone demethylase LSD1, shows substantial anti-tumor activity in a broad range of cancer cell lines and xenograft tumor models. …”
Publicado 2016
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1783“…Comparison among multiple sets used analysis of variance and LSD method or Kruskal-Wallis test and Nemenyi method. …”
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1784por Cong, Peifang, Liu, Yunen, Liu, Nannan, Zhang, Yubiao, Tong, Changci, Shi, Lin, Liu, Xuelei, Shi, Xiuyun, Liu, Ying, Tong, Zhou, Hou, Mingxiao“…One-way analysis of variance, followed by LSD-t test, was used to compare each variable for differences among the groups. …”
Publicado 2018
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1785por Zhou, Chao, Ma, Jie, Su, Mengyuan, Shao, Dan, Zhao, Jianan, Zhao, Tongjian, Song, Zhuoyao, Meng, Yan, Jiao, Ping“…The data were analyzed with two-sample Student’s t test and ANOVA followed by the LSD post hoc test. RESULTS: Our results showed that knockdown of STAT3 in ECA109 cells induced noticeable apoptotic morphological changes like cell shrinkage, apoptotic vacuoles, membrane blebbing time-dependently. …”
Publicado 2018
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1786por Jia, Lin, Wu, Dinglan, Wang, Yuliang, You, Wenxing, Wang, Zhu, Xiao, Lijia, Cai, Ganhui, Xu, Zhenyu, Zou, Chang, Wang, Fei, Teoh, Jeremy Yuen-Chun, Ng, Chi-Fai, Yu, Shan, Chan, Franky L.“…We also characterized that TLX could bind directly to AR promoter and repress AR transcription by recruitment of histone modifiers, including HDAC1, HDAC3, and LSD1. Together, our present study shows, for the first time, that TLX can contribute to androgen insensitivity in CRPC via repression of AR gene transcription and signaling, and also implicates that targeting the druggable TLX may have a potential therapeutic significance in CRPC management, particularly in NEPC and PCSCs.…”
Publicado 2018
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1787“…For inter-group comparisons ANOVA test followed by post hoc LSD test (when P < 0.05) were used. Significance level (α) was set to 0.05 in all cases. …”
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1788“…In adult OVX PNA mice, DHT increased firing rate of GnRH neurons relative to OVX PNA, but firing rate was still less than in sham-operated PNA animals (two-way ANOVA/Fisher’s LSD, n= 7-11 cells/group). In adult OVX control mice, preliminary data indicate that DHT replacement alone does not alter firing rate, in contrast to previous results with DHT plus estradiol. …”
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1789por Mohamed, Noha-Ehssan, Hay, Trevor, Reed, Karen R., Smalley, Matthew J., Clarke, Alan R.“…When more were compared, ANOVA test was used, followed by a post-hoc test (LSD or Games-Howell). P-values of < 0.05 were considered statistically significant. …”
Publicado 2019
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1790por Verri, Patrizia, Rustichelli, Cecilia, Ferrari, Anna, Marchesi, Filippo, Baraldi, Carlo, Licata, Manuela, Vandelli, Daniele, Palazzoli, Federica, Potì, Francesco, Silingardi, Enrico“…Especially from 2014, the range of seized substances increased and started to include synthetic cathinones, phenylethylamines, UR-144, LSD, psilocybe, prescription opioid and hypnotics. …”
Publicado 2019
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1791por Moyano, Javier, Mases, Laia, Izeta, Telmo, Flores, Teresa, Fernández-Bozal, Javier, Gil, Javier, Puigdollers, Andreu“…Each bracket model analysis—with the different wires, use of the FRA, and comparison among brackets in similar conditions—was done using an ANOVA test with a confidence interval of 95% and comparative Post-Hoc tests (LSD). In this in vitro simulation we found higher static friction values in CL compared to ASL and PSL. …”
Publicado 2019
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1792por Ebaid, Hossam, Bashandy, Samir A. E., Abdel-Mageed, Ahmad M., Al-Tamimi, Jameel, Hassan, Iftekhar, Alhazza, Ibrahim M.“…One-way ANOVA was used to compare those five subfields ability followed by LSD multiple comparisons. RESULTS: The data indicated that diabetes significantly altered the body weight, lipids and kidney function. …”
Publicado 2020
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1793por Anusuya, V., Nagar, Amit, Tandon, Pradeep, Singh, G. K., Singh, Gyan Prakash, Mahdi, A. A.“…Collected data were analyzed in SPSS software with a test of normalcy, unpaired t test, and one-way analysis of variance (ANOVA) followed by the least significant difference (LSD) post hoc comparison test and univariate regression analysis. …”
Publicado 2020
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1794por Specka, Michael, Kuhlmann, Thomas, Sawazki, Jürgen, Bonnet, Udo, Steinert, Renate, Cybulska-Rycicki, Monika, Eich, Helmut, Zeiske, Benita, Niedersteberg, Antje, Schaaf, Luzia, Scherbaum, Norbert“…The interview comprised classical substances of abuse, NPS, and rarely used substances such as LSD. In addition, participating sites had the opportunity to analyze their patients’ routine drug screenings by means of gas chromatography/mass spectrometry (GC/MS), which permitted detection of NPS. …”
Publicado 2020
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1795“…CONCLUSION: Differential atrophy patterns in the bilateral hippocampal subfield volumes could serve the differential diagnosis in patients with different causes of mild dementia: left CA1 for tAD; left presubiculum for LSD; right CA4/DG, right presubiculum, and right subiculum for RSD; CA4/DG and right CA2/3 for DLB; right CA2/3 and right CA4/DG for PCA. …”
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1796por Kong, Dejun, Hu, Yonghao, Li, Xiang, Yu, Dingding, Li, Hongyue, Zhao, Yiming, Qin, Yafei, Jin, Wang, Zhang, Baoren, Wang, Bo, Wang, Hongda, Li, Guangming, Wang, Hao“…Data were analyzed by one-way analysis of variance (ANOVA) after the normality test and followed by post hoc analysis with the least significant difference (LSD) test. RESULTS: IL-37-MSCs were able to migrate to the damaged tissue and significantly inhibit intestinal IRI. …”
Publicado 2020
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1797por Breeksema, Joost J., Niemeijer, Alistair R., Krediet, Erwin, Vermetten, Eric, Schoevers, Robert A.“…Substances included psilocybin, lysergic acid diethylamide (LSD), ibogaine, ayahuasca, ketamine and 3,4-methylenedioxymethamphetamine (MDMA). …”
Publicado 2020
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1798por Vardi, Ayelet, Ben-Dor, Shifra, Cho, Soo Min, Kalinke, Ulrich, Spanier, Julia, Futerman, Anthony H.“…However, this pathway is also induced in sterile inflammation such as that which occurs in a number of neurodegenerative diseases, including neuronopathic Gaucher disease (nGD), a lysosomal storage disorder (LSD) caused by mutations in GBA. METHODS: Mice were injected with conduritol B-epoxide, an irreversible inhibitor of acid beta-glucosidase, the enzyme defective in nGD. …”
Publicado 2020
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1799por Huang, Zhenlin, Ding, Yinghui, Zhang, Lu, He, Siyuan, Jia, Zhankui, Gu, Chaohui, Wang, Tao, Li, Hao, Li, Xiang, Jin, Zhibo, Ding, Yafei, Yang, Jinjian“…Student’s t-test, one-way ANOVA, Cox regression, an LSD-t-test, Pearson’s chi-squared test, a Log-rank test, and linear regression analyses were used to evaluate the group differences. …”
Publicado 2020
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1800por Heradstveit, Ove, Skogen, Jens Christoffer, Edland-Gryt, Marit, Hesse, Morten, Vallentin-Holbech, Lotte, Lønning, Kari-Jussie, Sivertsen, Børge“…The most commonly used illicit drugs during the past 12 months in 2018 were cannabis (15.2%), followed by MDMA (4.0%), cocaine (3.0%), and LSD/psilocybin (2.1%). Illicit drug use showed both linear increase with age, and inverted U-shaped relationships that peaked in the age span from 23 to 28 years of age. …”
Publicado 2020
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