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Mostrando 841 - 860 Resultados de 1,366 Para Buscar '"Leiden"', tiempo de consulta: 0.29s Limitar resultados
  1. 841
    “…This study aims to establish whether brain connectivity during rest is different in premanifest and manifest HD as compared to controls. METHODS: At the Leiden University Medical Centre study site of the TRACK-HD study, 20 early HD patients (disease stages 1 and 2), 28 premanifest gene carriers and 28 healthy controls underwent 3 T MRI scanning. …”
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    Reduced functional brain connectivity prior to and after disease onset in Huntington's disease()()
  2. 842
    “…METHODS: This retrospective cohort study included 108 patients with primary vulvar squamous cell carcinoma who were treated at the Leiden University Medical Center during 2000–2009. …”
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    Spindle cell morphology is related to poor prognosis in vulvar squamous cell carcinoma
  3. 843
    “…To determine if the deep vein thrombosis was of genetic origin, a peripheral blood DNA sample was analysed for the presence of the three most frequent mutations associated with thrombotic events: factor V Leiden (1691G>A), prothrombin (20210G>A) and methylene tetrahydrofolate reductase (677C>T). …”
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    A deep vein thrombosis caused by 20209C>T mutation in homozygosis of the prothrombin gene in a Caucasian patient
  4. 844
    “…There were (2) cases with factor V Leiden, (6) prothrombin gene mutation, (1) antithrombin III deficiency, (2) protein C deficiency, (3) protein S deficiency, (10) MTHFR mutation, (7) anti-cardiolipin antibodies, and (1) lupus anticoagulant. …”
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    Review of Management and Outcomes in Women with Thrombophilia Risk during Pregnancy at a Single Institution
  5. 845
    “…HbVar content was also inter-connected with two other established genetic databases, namely FINDbase (http://www.findbase.org) and Leiden Open-Access Variation database (http://www.lovd.nl), which allows comparative data querying and analysis. …”
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    Updates of the HbVar database of human hemoglobin variants and thalassemia mutations
  6. 846
    por Verschoor, Arie J, Gelderblom, Hans
    Publicado 2014
    “…This case series presents the incidence and clinic of this complication in the Leiden University Medical Centre. CASES: Forty-three patients were treated with pazopanib of which six patients (14.0%) developed a pneumothorax. …”
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    Pneumothorax as adverse event in patients with lung metastases of soft tissue sarcoma treated with pazopanib: a single reference centre case series
  7. 847
    “…The aim of this study was to investigate the prevalence of thromogenic gene mutations such as factor V Leiden (FVL, G1691T), prothrombin (G20210A), and the methylene tetrahydrofolate reductase (MTHFR, C677T) mutation in women with recurrent pregnancy loss. …”
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    Prevalence of thromogenic gene mutations in women with recurrent miscarriage: A retrospective study of 1,507 patients
  8. 848
    “…Here we show that BAT activation by β3-adrenergic receptor stimulation protects from atherosclerosis in hyperlipidemic APOE*3-Leiden.CETP mice, a well-established model for human-like lipoprotein metabolism that unlike hyperlipidemic Apoe(−/−) and Ldlr(−/−) mice expresses functional apoE and LDLR. …”
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    Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development
  9. 849
    “…All subjects were included from the Leiden Longevity Study and underwent 3 Tesla MTI of the brain. …”
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    An In Vivo Study on Brain Microstructure in Biological and Chronological Ageing
  10. 850
    “…Perceived age and skin wrinkling grade were assessed in a random sample from the Leiden Longevity Study with non-fasted (N = 579) and fasted blood sampling (N = 219). …”
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    Disentangling the effects of circulating IGF-1, glucose, and cortisol on features of perceived age
  11. 851
    “…Participants were: (1) patients with unprovoked VTE with either factor V Leiden mutation or G20210A prothrombin gene mutation or not; and (2) their first-degree relatives. …”
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    A Qualitative Study to Appraise Patients and Family Members Perceptions, Knowledge, and Attitudes towards Venous Thromboembolism Risk
  12. 852
    “…BACKGROUND: Recurrent pregnancy loss (RPL) is caused by different factors, including genetics and thrombophilia. Beside Factor V Leiden, another nucleotide change in a factor V (FV) gene (A4070G; His1299Arg) has been identified linking to hereditary thrombophilia. …”
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    H1299R in coagulation Factor V and Glu429Ala in MTHFR genes in recurrent pregnancy loss in Sari, Mazandaran
  13. 853
    “…In the current paper, we aim to classify a group of older people into those with longevity potential or controls. METHODS: In the Leiden Longevity Study participated 1671 offspring of nonagenarian siblings, as the group with longevity potential, and 744 similarly aged controls. …”
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    Classification for Longevity Potential: The Use of Novel Biomarkers
  14. 854
    “…CASE PRESENTATION: Five patients with unresectable or metastatic chordoma were treated with VEGFR inhibitors pazopanib or sunitinib in the Leiden University Medical Centre (LUMC) between 2008 and 2015. …”
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    Efficacy of pazopanib and sunitinib in advanced axial chordoma: a single reference centre case series
  15. 855
    “…METHODS: We analyzed the prevalence of 13 hemostatic polymorphisms [PAI-1, PLAT, F5 (including factor V Leiden and HR2 haplotype), F2, F7, F13A, FGB, TFPI, THBD, MTHFR, ACE, and ITGA2] in patients referred to a tertiary referral center. …”
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    A Prothrombotic Score Based on Genetic Polymorphisms of the Hemostatic System Differs in Patients with Ischemic Stroke, Myocardial Infarction, or Peripheral Arterial Occlusive Disease
  16. 856
    “…The Female Cancer Program from Jakarta Regional collaborated with Leiden University in 2007 to 2011 has done cervical cancer screening using VIA method, involving 25,406 women spreading across several primary health centers in Jakarta. …”
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    Prevalence, Age Distribution, and Risk Factors of Visual Inspection With Acetic Acid-Positive From 2007 to 2011 in Jakarta
  17. 857
    “…Compared with nonusers, the CHC users experienced more frequently pulmonary embolism: odds ratio (OR) = 1.28 (1.06–1.55; 95% confidence interval [CI]), factor V Leiden mutations were more frequent in this group (OR = 1.41 [1.11–1.80; 95% CI]). …”
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    First venous thromboembolism and hormonal contraceptives in young French women
  18. 858
    “…METHODS: Quality of life was assessed using the Short-Form 36 item Health Survey (SF-36) in patients visiting the Leiden NPSLE clinic at baseline and at follow-up. …”
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    Neuropsychiatric symptoms in systemic lupus erythematosus: impact on quality of life
  19. 859
    “…The influence of thrombosis on the prognosis of patients with hepatocellular carcinoma (HCC) after liver transplantation (LT) and the role of the commonest inherited thrombophilia abnormalities factor V Leiden and prothrombin G20210A in the development of thrombosis are unknown. …”
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    Thrombosis after liver transplantation for hepatocellular carcinoma
  20. 860
    por Abdi, Abshir Ali, Osman, Abdimajid
    Publicado 2017
    “…As expected, we found no existence of factor V Leiden (rs6025) and prothrombin G20210A (rs1799963) in the Somali population. …”
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    Prevalence of common hereditary risk factors for thrombophilia in Somalia and identification of a novel Gln544Arg mutation in coagulation factor V
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