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5961por Cazan, Cristina Daniela, Ionică, Angela Monica, Matei, Ioana Adriana, D’Amico, Gianluca, Muñoz, Clara, Berriatua, Eduardo, Dumitrache, Mirabela Oana“…The travel of infected dogs may introduce the infection to areas where leishmaniasis is not present.…”
Publicado 2020
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5962por Castelli, Germano, Bruno, Federica, Caputo, Valentina, Fiorella, Santi, Sammarco, Ignazio, Lupo, Tiziana, Migliazzo, Antonella, Vitale, Fabrizio, Reale, Stefano“…BACKGROUND: Leishmaniasis is one of the most important vector-borne diseases and it represents a serious world health problem affecting millions of people. …”
Publicado 2020
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5963por Aramin, Samar, Fassler, Rosi, Chikne, Vaibhav, Goldenberg, Mor, Arian, Tal, Kolet Eliaz, Liat, Rimon, Oded, Ram, Oren, Michaeli, Shulamit, Reichmann, Dana“…Using a bioinformatic analysis, we describe novel eukaryotic homologs of Hsp33 identified in eukaryotic pathogens belonging to the kinetoplastids, a family responsible for lethal human diseases such as Chagas disease as caused by Trypanosoma cruzi, African sleeping sickness caused by Trypanosoma brucei spp., and leishmaniasis pathologies delivered by various Leishmania species. …”
Publicado 2020
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5964por Resende, Lucilene Aparecida, Aguiar-Soares, Rodrigo Dian de Oliveira, Moreira, Nádia das Dores, Ferreira, Sidney de Almeida, Lanna, Mariana Ferreira, Cardoso, Jamille Mirelle de Oliveira, Mathias, Fernando Augusto Siqueira, Coura-Vital, Wendel, Mariano, Reysla Maria da Silveira, Leite, Jaqueline Costa, Silveira, Patricia, de Carvalho, Tatiane Furtado, Santos, Renato Lima, da Silveira-Lemos, Denise, Martins-Filho, Olindo Assis, Dutra, Walderez Ornelas, Reis, Alexandre Barbosa, Giunchetti, Rodolfo Cordeiro“…Visceral leishmaniasis (VL) is a severe disease caused by Leishmania infantum. …”
Publicado 2020
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5965por de Goes, Tayná C., de Morais, Rayana C. S., de Melo, Maria G. N., e Silva, Rômulo P., Rezende, Antônio M., de Paiva-Cavalcanti, Milena“…The causative species is an important factor influencing the evolution of American cutaneous leishmaniasis (ACL). Due to its wide distribution in endemic areas, Leishmania (V.) braziliensis is considered one of the most important species in circulation in Brazil. …”
Publicado 2020
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5966por González, Mikel A., Bell, Melissa, Souza, Cristian F., Maciel-de-Freitas, Rafael, Brazil, Reginaldo P., Courtenay, Orin, Hamilton, James G. C.“…BACKGROUND: In South America the sand fly Lutzomyia longipalpis is the predominant vector of Leishmania infantum, the parasite that causes canine and human visceral leishmaniasis. Co-location of synthetic male sex-aggregation pheromone with an insecticide provided protection against canine seroconversion, parasite infection, reduced tissue parasite loads, and female sand fly densities at households. …”
Publicado 2020
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5967Synthesis and antileishmanial effect of a few cyclic and non-cyclic n-aryl enamino amide derivatives“…BACKGROUND AND PURPOSE: The prevalence of leishmaniasis is reported in more than 98 countries and Iran is one of the endemic areas. …”
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5968por Yu, Baozhong, Zhang, Jiandong, Sun, Zejia, Cao, Peng, Zheng, Xiang, Gao, Zihao, Cao, Haoyuan, Zhang, Feilong, Wang, Wei“…Functional enrichment analysis by gene ontology and Kyoto Encyclopedia of Genes and Genomes highlighted enrichment of neutrophil degranulation, phagocytosis and vesicle-mediated transport regulation, and pathways including tuberculosis, toxoplasmosis, phagosome, leishmaniasis, and Fc gamma R-mediated. CONCLUSIONS: IFI16 is overexpressed in RCC and may be an important oncogene in the progression of kidney. …”
Publicado 2021
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5969por Merdekios, Behailu, Pareyn, Myrthe, Tadesse, Dagimawie, Eligo, Nigatu, Kassa, Mekibib, Jacobs, Bart K. M., Leirs, Herwig, Van Geertruyden, Jean-Pierre, van Griensven, Johan, Caljon, Guy, Cnops, Lieselotte“…In most low-resource settings, microscopy still is the standard method for diagnosis of cutaneous leishmaniasis, despite its limited sensitivity. In Ethiopia, the more sensitive molecular methods are not yet routinely used. …”
Publicado 2021
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5970por Ilaghi, Mozhde, Sharifi, Iraj, Sharififar, Fariba, Sharifi, Fatemeh, Oliaee, Razieh Tavakoli, Babaei, Zahra, Meimamandi, Manzume Shamsi, Keyhani, Alireza, Bamorovat, Mehdi“…INTRODUCTION: Treatment of leishmaniasis with conventional synthetic drugs is a major global challenge. …”
Publicado 2021
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5971por Ohms, Mareike, Ferreira, Carolina, Busch, Hauke, Wohlers, Inken, Guerra de Souza, Ana Cristina, Silvestre, Ricardo, Laskay, Tamás“…Visceral leishmaniasis (VL) is a fatal parasitic disease if untreated. …”
Publicado 2021
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5972por Bamra, Tanvir, Shafi, Taj, Das, Sushmita, Kumar, Manjay, Dikhit, Manas Ranjan, Kumar, Ajay, Kumar, Ashish, Abhishek, Kumar, Pandey, Krishna, Sen, Abhik, Das, Pradeep“…Cellular functions of one such novel protein: mevalonate kinase is discussed here; signifying its importance in Leishmania infection. Visceral Leishmaniasis is a persistent infection, caused by Leishmania donovani in Indian subcontinent. …”
Publicado 2021
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5973por Zorrilla, Victor O., Lozano, Marisa E., Espada, Liz J., Kosoy, Michael, McKee, Clifton, Valdivia, Hugo O., Arevalo, Heriberto, Troyes, Mario, Stoops, Craig A., Fisher, Michael L., Vásquez, Gissella M.“…BACKGROUND: In Peru, the information regarding sand fly vectors of leishmaniasis and bartonellosis in the Amazon region is limited. …”
Publicado 2021
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5974por Silva-Silva, João Victor, Moragas-Tellis, Carla Junqueira, Chagas, Maria do Socorro dos Santos, de Souza, Paulo Victor Ramos, de Souza, Celeste da Silva Freitas, Hardoim, Daiana de Jesus, Taniwaki, Noemi Nosomi, Moreira, Davyson de Lima, Dutra Behrens, Maria, Calabrese, Kátia da Silva, Almeida-Souza, Fernando“…Acknowledging the need of identifying new compounds for the treatment of leishmaniasis, this study aimed to evaluate, from in vitro trials, the activity of flavones from Arrabidaea chica against L. amazonensis. …”
Publicado 2021
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5975por Montoya, Alba L., Austin, Victoria M., Portillo, Susana, Vinales, Irodiel, Ashmus, Roger A., Estevao, Igor, Jankuru, Sohan R., Alraey, Yasser, Al-Salem, Waleed S., Acosta-Serrano, Álvaro, Almeida, Igor C., Michael, Katja“…This method was tested here seeking to identify as-yet unknown glycotopes specific for Leishmania major, the causative agent of Old-World cutaneous leishmaniasis (OWCL). Neoglycoproteins decorated with synthetic α-Gal-containing oligosaccharides derived from L. major glycoinositolphospholipids served as antigens in a chemiluminescent enzyme-linked immunosorbent assay using sera from OWCL patients and noninfected individuals. …”
Publicado 2021
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5976por de Oliveira, Beatriz C. D., Shiburah, Mark E., Paiva, Stephany C., Vieira, Marina R., Morea, Edna Gicela O., da Silva, Marcelo Santos, Alves, Cristiane de Santis, Segatto, Marcela, Gutierrez-Rodrigues, Fernanda, Borges, Júlio C., Calado, Rodrigo T., Cano, Maria Isabel N.“…The disruption of this cycle is critical for discovering new therapies to eradicate leishmaniasis, a neglected disease that affects millions worldwide. …”
Publicado 2021
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5977por Espada, Caroline R., Quilles, José Carlos, Albuquerque-Wendt, Andreia, Cruz, Mario C., Beneke, Tom, Lorenzon, Lucas B., Gluenz, Eva, Cruz, Angela K., Uliana, Silvia R. B.“…In South America, and especially in Brazil, Leishmania (Viannia) braziliensis is the most frequent etiological agent of tegumentary leishmaniasis. The L. braziliensis β-tubulin locus presents significant sequence divergence in comparison with Leishmania major, which precludes the efficient integration of pTB007 and the stable expression of Cas9. …”
Publicado 2021
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5978por da Silva, Raíssa Bernardes, Bertoldo, Willian dos Reis, Naves, Lucila Langoni, de Vito, Fernanda Bernadelli, Damasceno, Jeziel Dener, Tosi, Luiz Ricardo Orsini, Machado, Carlos Renato, Pedrosa, André Luiz“…Leishmania parasites are the causative agents of a group of neglected tropical diseases known as leishmaniasis. The molecular mechanisms employed by these parasites to adapt to the adverse conditions found in their hosts are not yet completely understood. …”
Publicado 2022
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5979por Dias, Bruna T., Goundry, Amy, Vivarini, Aislan C., Costa, Tatiana F. R., Mottram, Jeremy C., Lopes, Ulisses G., Lima, Ana Paula C. A.“…Leishmania donovani is a protozoan parasite that causes visceral leishmaniasis, provoking liver and spleen tissue destruction that is lethal unless treated. …”
Publicado 2022
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5980por Anuntasomboon, Pornchai, Siripattanapipong, Suradej, Unajak, Sasimanas, Choowongkomon, Kiattawee, Burchmore, Richard, Leelayoova, Saovanee, Mungthin, Mathirut, E-kobon, Teerasak“…ABSTRACT: (1) Background: Autochthonous leishmaniasis, a sandfly-borne disease caused by the protozoan parasites Leishmania orientalis (formerly named Leishmania siamensis) and Leishmania martiniquensis, has been reported for immunocompromised and immunocompetent patients in the southern province of Thailand. …”
Publicado 2022
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