Mechanistic and structural insight into the functional dichotomy between interleukin-2 and interleukin-15

por Ring, Aaron M., Lin, Jian-Xin, Feng, Dan, Mitra, Suman, Rickert, Mathias, Bowman, Gregory R., Pande, Vijay S., Li, Peng, Moraga, Ignacio, Spolski, Rosanne, Özkan, Engin, Leonard, Warren J., Garcia, K. Christopher
Publicado 2012

Stat5 Synergizes with T Cell Receptor/Antigen Stimulation in the Development of Lymphoblastic Lymphoma

por Kelly, John A., Spolski, Rosanne, Kovanen, Panu E., Suzuki, Takeshi, Bollenbacher, Julie, Pise-Masison, Cynthia A., Radonovich, Michael F., Lee, Stephen, Jenkins, Nancy A., Copeland, Neal G., Morse, Herbert C., Leonard, Warren J.
Publicado 2003

Transient expression of ZBTB32 in anti-viral CD8(+) T cells limits the magnitude of the effector response and the generation of memory

por Shin, Hyun Mu, Kapoor, Varun N., Kim, Gwanghun, Li, Peng, Kim, Hang-Rae, Suresh, M., Kaech, Susan M., Wherry, E. John, Selin, Liisa K., Leonard, Warren J., Welsh, Raymond M., Berg, Leslie J.
Publicado 2017

Crosstalk between ILC2s and Th2 cells varies among mouse models

por Gurram, Rama K., Wei, Danping, Yu, Qiao, Butcher, Matthew J., Chen, Xi, Cui, Kairong, Hu, Gangqing, Zheng, Mingzhu, Zhu, Xiaoliang, Oh, Jangsuk, Sun, Bing, Urban, Joseph F., Zhao, Keji, Leonard, Warren J., Zhu, Jinfang
Publicado 2023

Synergy of IL-21 and IL-15 in regulating CD8(+) T cell expansion and function

por Zeng, Rong, Spolski, Rosanne, Finkelstein, Steven E., Oh, SangKon, Kovanen, Panu E., Hinrichs, Christian S., Pise-Masison, Cynthia A., Radonovich, Michael F., Brady, John N., Restifo, Nicholas P., Berzofsky, Jay A., Leonard, Warren J.
Publicado 2005

IFNγ regulates NAD(+) metabolism to promote the respiratory burst in human monocytes

por McCann, Katelyn J., Christensen, Stephen M., Colby, Devon H., McGuire, Peter J., Myles, Ian A., Zerbe, Christa S., Dalgard, Clifton L., Sukumar, Gauthaman, Leonard, Warren J., McCormick, Beth A., Holland, Steven M.
Publicado 2022

Atopic Dermatitis-Like Disease and Associated Lethal Myeloproliferative Disorder Arise from Loss of Notch Signaling in the Murine Skin

por Dumortier, Alexis, Durham, André-Dante, Di Piazza, Matteo, Vauclair, Sophie, Koch, Ute, Ferrand, Gisèle, Ferrero, Isabel, Demehri, Shadmehr, Song, Lynda Li, Farr, Andrew G., Leonard, Warren J., Kopan, Raphael, Miele, Lucio, Hohl, Daniel, Finke, Daniela, Radtke, Freddy
Publicado 2010

Engineered cytokine/antibody fusion proteins improve delivery of IL-2 to pro-inflammatory cells and promote antitumor activity

por Leonard, Elissa K., Tomala, Jakub, Gould, Joseph R., Leff, Michael I., Lin, Jian-Xin, Li, Peng, Porter, Mitchell J., Johansen, Eric R., Thompson, Ladaisha, Cao, Shanelle D., Henclova, Tereza, Huliciak, Maros, Vaněk, Ondřej, Kovar, Marek, Leonard, Warren J., Spangler, Jamie B.
Publicado 2023

IL-21 Is an Antitolerogenic Cytokine of the Late-Phase Alloimmune Response

por Petrelli, Alessandra, Carvello, Michele, Vergani, Andrea, Lee, Kang Mi, Tezza, Sara, Du, Ming, Kleffel, Sonja, Chengwen, Liu, Mfarrej, Bechara G., Hwu, Patrick, Secchi, Antonio, Leonard, Warren J., Young, Deborah, Sayegh, Mohamed H., Markmann, James F., Zajac, Allan J., Fiorina, Paolo
Publicado 2011

Investigation of the causal etiology in a patient with T-B+NK+ immunodeficiency

por Sertori, Robert, Lin, Jian-Xin, Martinez, Esteban, Rana, Sadhna, Sharo, Andrew, Kazemian, Majid, Sunderam, Uma, Andrake, Mark, Shinton, Susan, Truong, Billy, Dunbrack, Roland M., Liu, Chengyu, Srinivasan, Rajgopol, Brenner, Steven E., Seroogy, Christine M., Puck, Jennifer M., Leonard, Warren J., Wiest, David L.
Publicado 2022

Calibration of cell-intrinsic interleukin-2 response thresholds guides design of a regulatory T cell biased agonist

por Glassman, Caleb R, Su, Leon, Majri-Morrison, Sonia S, Winkelmann, Hauke, Mo, Fei, Li, Peng, Pérez-Cruz, Magdiel, Ho, Peggy P, Koliesnik, Ievgen, Nagy, Nadine, Hnizdilova, Tereza, Picton, Lora K, Kovar, Marek, Bollyky, Paul, Steinman, Lawrence, Meyer, Everett, Piehler, Jacob, Leonard, Warren J, Garcia, K Christopher
Publicado 2021

Act1 is a negative regulator in T and B cells via direct inhibition of STAT3

por Zhang, Cun-Jin, Wang, Chenhui, Jiang, Meiling, Gu, Chunfang, Xiao, Jianxin, Chen, Xing, Martin, Bradley N., Tang, Fangqiang, Yamamoto, Erin, Xian, Yibo, Wang, Han, Li, Fengling, Sartor, R. Balfour, Smith, Howard, Husni, M. Elaine, Shi, Fu-Dong, Gao, Ji, Carman, Julie, Dongre, Ashok, McKarns, Susan C., Coppieters, Ken, Jørgensen, Trine N., Leonard, Warren J., Li, Xiaoxia
Publicado 2018

Potentiating adoptive cell therapy using synthetic IL-9 receptors

por Kalbasi, Anusha, Siurala, Mikko, Su, Leon L., Tariveranmoshabad, Mito, Picton, Lora K., Ravikumar, Pranali, Li, Peng, Lin, Jian-Xin, Escuin-Ordinas, Helena, Da, Tong, Kremer, Sarah V., Sun, Amy L., Castelli, Sofia, Agarwal, Sangya, Scholler, John, Song, Decheng, Rommel, Philipp C., Radaelli, Enrico, Young, Regina M., Leonard, Warren J., Ribas, Antoni, June, Carl H., Garcia, K. Christopher
Publicado 2022

Publisher Correction: Potentiating adoptive cell therapy using synthetic IL-9 receptors

por Kalbasi, Anusha, Siurala, Mikko, Su, Leon L., Tariveranmoshabad, Mito, Picton, Lora K., Ravikumar, Pranali, Li, Peng, Lin, Jian-Xin, Escuin-Ordinas, Helena, Da, Tong, Kremer, Sarah V., Sun, Amy L., Castelli, Sofia, Agarwal, Sangya, Scholler, John, Song, Decheng, Rommel, Philipp C., Radaelli, Enrico, Young, Regina M., Leonard, Warren J., Ribas, Antoni, June, Carl H., Garcia, K. Christopher
Publicado 2022

Compensatory dendritic cell development mediated by BATF-IRF interactions

por Tussiwand, Roxane, Lee, Wan-Ling, Murphy, Theresa L., Mashayekhi, Mona, Wumesh, KC, Albring, Jörn C., Satpathy, Ansuman T., Rotondo, Jeffrey A., Edelson, Brian T., Kretzer, Nicole M., Wu, Xiaodi, Weiss, Leslie A., Glasmacher, Elke, Li, Peng, Liao, Wei, Behnke, Michael, Lam, Samuel S.K., Aurthur, Cora T., Leonard, Warren J., Singh, Harinder, Stallings, Christina L., Sibley, L. David, Schreiber, Robert D., Murphy, Kenneth M.
Publicado 2012

Design of cell-type-specific hyperstable IL-4 mimetics via modular de novo scaffolds

por Yang, Huilin, Ulge, Umut Y., Quijano-Rubio, Alfredo, Bernstein, Zachary J., Maestas, David R., Chun, Jung-Ho, Wang, Wentao, Lin, Jian-Xin, Jude, Kevin M., Singh, Srujan, Orcutt-Jahns, Brian T., Li, Peng, Mou, Jody, Chung, Liam, Kuo, Yun-Huai, Ali, Yasmin H., Meyer, Aaron S., Grayson, Warren L., Heller, Nicola M., Christopher Garcia, K., Leonard, Warren J., Silva, Daniel-Adriano, Elisseeff, Jennifer H., Baker, David, Spangler, Jamie B.
Publicado 2023

BACH2 regulates CD8(+) T cell differentiation by controlling access of AP-1 factors to enhancers

por Roychoudhuri, Rahul, Clever, David, Li, Peng, Wakabayashi, Yoshiyuki, Quinn, Kylie M., Klebanoff, Christopher A., Ji, Yun, Sukumar, Madhusudhanan, Eil, Robert L., Yu, Zhiya, Spolski, Rosanne, Palmer, Douglas C., Pan, Jenny H., Patel, Shashank J., Macallan, Derek C, Fabozzi, Giulia, Shih, Han-Yu, Kanno, Yuka, Muto, Akihiko, Zhu, Jun, Gattinoni, Luca, O’Shea, John J., Okkenhaug, Klaus, Igarashi, Kazuhiko, Leonard, Warren J., Restifo, Nicholas P.
Publicado 2016

NetPath: a public resource of curated signal transduction pathways

por Kandasamy, Kumaran, Mohan, S Sujatha, Raju, Rajesh, Keerthikumar, Shivakumar, Kumar, Ghantasala S Sameer, Venugopal, Abhilash K, Telikicherla, Deepthi, Navarro, J Daniel, Mathivanan, Suresh, Pecquet, Christian, Gollapudi, Sashi Kanth, Tattikota, Sudhir Gopal, Mohan, Shyam, Padhukasahasram, Hariprasad, Subbannayya, Yashwanth, Goel, Renu, Jacob, Harrys KC, Zhong, Jun, Sekhar, Raja, Nanjappa, Vishalakshi, Balakrishnan, Lavanya, Subbaiah, Roopashree, Ramachandra, YL, Rahiman, B Abdul, Prasad, TS Keshava, Lin, Jian-Xin, Houtman, Jon CD, Desiderio, Stephen, Renauld, Jean-Christophe, Constantinescu, Stefan N, Ohara, Osamu, Hirano, Toshio, Kubo, Masato, Singh, Sujay, Khatri, Purvesh, Draghici, Sorin, Bader, Gary D, Sander, Chris, Leonard, Warren J, Pandey, Akhilesh
Publicado 2010

De novo sequencing, assembly and analysis of eight different transcriptomes from the Malayan pangolin

por Mohamed Yusoff, Aini, Tan, Tze King, Hari, Ranjeev, Koepfli, Klaus-Peter, Wee, Wei Yee, Antunes, Agostinho, Sitam, Frankie Thomas, Rovie-Ryan, Jeffrine Japning, Karuppannan, Kayal Vizi, Wong, Guat Jah, Lipovich, Leonard, Warren, Wesley C., O’Brien, Stephen J., Choo, Siew Woh
Publicado 2016