“…Purified Pif1 protein strongly stimulates Polδ-mediated DNA synthesis from a D-loop made by the Rad51 recombinase. Importantly, Pif1 liberates the newly synthesized strand to prevent the accumulation of topological constraint and to facilitate extensive DNA synthesis via the establishment of a migrating D-loop structure. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This undersupply is concurrent with globalization and the resulting liberalization of markets, which allow health workers to offer their services in countries other than those of their origin. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The effects of the CO liberator tricarbonylchloro(glycinato)ruthenium (II) (CORM-3) on the induction of RAR were examined by transferring the irradiated embryos to freshly prepared medium with the chemical at different time points after the application of the priming dose. …”
Enlace del recurso
Enlace del recurso

“…With the environmental pH being reduced from pH 7.4 to 4.7, the drug liberation was appreciably promoted by the massive disruption of the ionic γ-GA/DOX complexes along with the significant swelling of nanogel layers upon the increased protonation of chitosan chain segments. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Upon satisfaction of both pathways, the APC/C(Cdc20) elicits the degradation of securin and cyclin B [3]. This liberates separase triggering sister chromatid disjunction and inactivates cyclin-dependent kinase 1 (Cdk1) causing mitotic exit. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…After internalization into cells, the GN3-ASO conjugate is metabolized to liberate the parent ASO in the liver. No metabolism of the GN3-ASO conjugate was detected in plasma suggesting that GN3 acts as a hepatocyte targeting prodrug that is detached from the ASO by metabolism after internalization into the liver. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…However, entrapped S. pyogenes can circumvent the antimicrobial effect of the clot by sequestering host plasminogen on the bacterial cell surface that, after conversion into its active proteolytic form, plasmin, degrades the fibrin network and facilitates the liberation of S. pyogenes from the clot. Furthermore, the surface-localized fibrinolytic activity also cleaves a variety of extracellular matrix proteins, thereby enabling S. pyogenes to migrate across barriers and disseminate within the host. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Z. filipendulae and L. corniculatus both contain the two cyanogenic glucosides linamarin and lotaustralin, which are defense compounds that can be hydrolyzed to liberate toxic hydrogen cyanide. The overall amounts and ratios of linamarin and lotaustralin in Z. filipendulae are tightly regulated, and only to a low extent reflect the ratio in the ingested food-plant. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…There is reduced vascularity as the disease advances and this denies the systemic absorption of carcinogens, which affects the already compromised epithelium. Consequently, liberation of angiogenic factors occurs because of malignant transformation, which explains the neoangiogenesis and increased vascularity in OSMF turning towards malignancy. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Fucosylated proteins are shed into the lumen and fucose is liberated and metabolized by the gut microbiota, as shown by reporter bacteria and community-wide analysis of microbial gene expression. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Cellular degeneration in MS lesions leads to waves of iron liberation, which may propagate neurodegeneration together with inflammatory oxidative burst.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Geochemical reactions associated with serpentinization alter the composition of dissolved organic compounds in circulating fluids and potentially liberate mantle-derived carbon and reducing power to support subsurface microbial communities. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In SSc anti-endothelial cell antibodies impair vascular endothelium and liberation of vasoconstrictors leads to BP increasing and disruption of blood-brain barrier autoregulation mechanisms. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…METHODS: Clinical data from 39 patients with LD-SCEC treated in the Chinese People’s Liberation Army General Hospital, Beijing, China between 2000 and 2013 were retrospectively collected with regard to pathologic characteristics, overall survival (OS), and relevant prognostic factors. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…RESULTS: Two LC-MS/MS methods were developed and validated and successfully applied to analyze the parent drug molecules and aglycones liberated from plasma samples via β-glucuronidase hydrolysis. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In vitro drug delivery studies demonstrated initial burst liberation of FA within 24 h followed by a sustained release for the subsequent time. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…ES was significantly associated with an individual's egalitarianism and political liberalism, having illness/disability, having no additional private health insurance, and their perception of health insurance coverage. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Hence, we posit that in addition to its well-known role in stimulating cellular metabolism in response to nutrients, TOR also promotes wing growth by liberating Yki from nuclear seclusion, a parallel pathway that we propose contributes to the scaling of wing size with nutrient availability.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Finally, constraints burdened on our cognition with language and the possibility of liberation from them are discussed. Main arguments: (1) Maturana’s ‘coordination’ and Sartre’s ‘reflection’ are operationally equivalent concepts; (2) Sartre can complement Maturana’s languaging theory of naming by providing both the domain for naming (the domain for the synthesis of identification, or for universalizing synthesis) and a mediator of naming (the cogito, namely the consciousness, of a languaging person).…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…As the sepsis resolved, arterial ECMO support was weaned under echocardiographic guidance; subsequent resolution of intrinsic respiratory function allowed the weaning of VV-ECMO support. The patient was liberated from ECMO 7 days after hospital admission.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso