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5161por Gennari, Arianna, Rios de la Rosa, Julio M, Hohn, Erwin, Pelliccia, Maria, Lallana, Enrique, Donno, Roberto, Tirella, Annalisa, Tirelli, Nicola“…The nanoparticles are composed of hyaluronic acid (HA) and chitosan; the former can address a nanoparticle to cell surface receptors such as CD44, the second allows both for entrapment of nucleic acids and for an endosomolytic activity that facilitates their liberation in the cytoplasm. Here, we have systematically compared nanoparticles prepared either A) through a two-step process based on intermediate (template) particles produced via ionotropic gelation of chitosan with triphosphate (TPP), which are then incubated with HA, or B) through direct polyelectrolyte complexation of chitosan and HA. …”
Publicado 2019
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5162por Neyer, Peter, Bernasconi, Luca, Fuchs, Jens A., Allenspach, Martina D., Steuer, Christian“…Four hundred microliters of Li‐heparin plasma and urine were analyzed after liberation of volatile amines under heated conditions in an aqueous alkaline and saline environment. …”
Publicado 2019
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5163por Galli, Ubaldina, Colombo, Giorgia, Travelli, Cristina, Tron, Gian Cesare, Genazzani, Armando A., Grolla, Ambra A.“…On the other hand, the nicotinamide that is liberated by NAD-consuming enzymes can be salvaged to re-form NAD. …”
Publicado 2020
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5164por Hassan, Noor, Anesio, Alexandre M., Rafiq, Muhammad, Holtvoeth, Jens, Bull, Ian, Haleem, Abdul, Shah, Aamer Ali, Hasan, Fariha“…In the present study, 42 bacterial strains were isolated from the Ghulmet, Ghulkin, and Hopar glaciers of the Hunza Valley in the Karakoram Mountain Range, Pakistan and their cell membrane fatty acid distributions studied, using gas chromatography/mass spectrometry (GC-MS) for the analysis of fatty acid methyl esters (FAMEs) liberated by acid-catalyzed methanolysis. Furthermore, Gram-negative and Gram-positive groups were grown under different temperature settings (5, 15, 25, and 35°C) in order to determine the effect of temperature on cell membrane (CM) fatty acid distribution. …”
Publicado 2020
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5165“…The glucometer manufacturers have an active role to play in liberalizing QC settings and also enhancing the middleware to facility patient-based QC practices.…”
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5166por Cenens, William, Andrade, Maxuel O., Llontop, Edgar, Alvarez-Martinez, Cristina E., Sgro, Germán G., Farah, Chuck S.“…This capability represents an obvious fitness benefit since it can eliminate competition while the liberated contents of the lysed bacteria could provide an increase in the local availability of nutrients. …”
Publicado 2020
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5167“…Method: We identified retrospectively those diagnosed with pulmonary cryptococcosis in the first medical center of Chinese People’s Liberation Army General Hospital since 2009 to 2019. …”
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5168“…In this study, chemical pulping was the chosen process for liberating the fibres as it is effective in dissolving lignin embedded within the cellulose. …”
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5169por Hazbun, Munir E., Faust, Andrew C., Ortegon, Anthony L., Sheperd, Lyndsay A., Weinstein, Gary L., Doebele, Rebecca L., Weinmeister, Kenney D., Liddell, Allison M., Feldman, Mark“…Twenty of 21 patients (95%) have been liberated from mechanical ventilation after a median duration of 8 days (range, 4–30 d). …”
Publicado 2020
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5170por Spriewald, Stefanie, Stadler, Eva, Hense, Burkhard A., Münch, Philipp C., McHardy, Alice C., Weiss, Anna S., Obeng, Nancy, Müller, Johannes, Stecher, Bärbel“…While group A colicins employ a division of labor strategy to liberate the toxin into the environment via colicin-specific lysis, group B colicin systems lack cognate lysis genes. …”
Publicado 2020
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5171por Cui, Pengfei, Li, Ruixin, Huang, Ziwei, Wu, Zhaozhen, Tao, Haitao, Zhang, Sujie, Hu, Yi“…This study included patients with recurrent or advanced NSCLC diagnosed between September 1, 2015 and August 31, 2019, who were treated with programmed cell death 1 (PD-1) inhibitors at the Cancer Center of the Chinese People’s Liberation Army. PFS was estimated for each treatment group using Kaplan–Meier curves and log-rank tests. …”
Publicado 2020
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5172por Shuman, Stewart“…Because eukaryal genomes are liberally interspersed with transcription units specifying long non-coding (lnc) RNAs, there are many opportunities for lncRNA synthesis to negatively affect a neighboring protein-coding gene. …”
Publicado 2020
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5173por Knott, Brandon C., Erickson, Erika, Allen, Mark D., Gado, Japheth E., Graham, Rosie, Kearns, Fiona L., Pardo, Isabel, Topuzlu, Ece, Anderson, Jared J., Austin, Harry P., Dominick, Graham, Johnson, Christopher W., Rorrer, Nicholas A., Szostkiewicz, Caralyn J., Copié, Valérie, Payne, Christina M., Woodcock, H. Lee, Donohoe, Bryon S., Beckham, Gregg T., McGeehan, John E.“…Specifically, the I. sakaiensis PETase depolymerizes PET, liberating soluble products, including mono(2-hydroxyethyl) terephthalate (MHET), which is cleaved to terephthalic acid and ethylene glycol by MHETase. …”
Publicado 2020
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5174por Norton, Dustin L., Ceppe, Agathe, Tune, Miriya K., McCravy, Matthew, Devlin, Thomas, Drummond, M. Bradley, Carson, Shannon S., Vincent, Benjamin G., Hagan, Robert S., Dang, Hong, Doerschuk, Claire M., Mock, Jason R.“…We hypothesized that patients whose lung injury resolves quickly, as measured by time to liberation from mechanical ventilation, have a higher percentage of Tregs amongst CD4(+) T cells in either airway, bronchoalveolar lavage (BAL) or peripheral blood samples. …”
Publicado 2020
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5175por Friedman, Samuel R., Krawczyk, Noa, Perlman, David C., Mateu-Gelabert, Pedro, Ompad, Danielle C., Hamilton, Leah, Nikolopoulos, Georgios, Guarino, Honoria, Cerdá, Magdalena“…All three of these roots of the crisis—pharmaceutical misconduct and unethical marketing practices, despair based on deindustrialization and increased occupational pain—can be traced back, in part, to what has been called the “one-sided class war” that became prominent in the 1970s, became institutionalized as neo-liberalism in and since the 1980s, and may now be beginning to be challenged. …”
Publicado 2020
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5176“…The current interest in further liberalizing preoperative fluid intake will require more change in anesthesia culture.…”
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5177por Al-Hashimi, Alaa, Venugopalan, Vaishnavi, Rehders, Maren, Sereesongsaeng, Naphannop, Hein, Zeynep, Springer, Sebastian, Weber, Ekkehard, Führer, Dagmar, Bogyo, Matthew S., Scott, Christopher J., Burden, Roberta E., Brix, Klaudia“…The significance of cysteine cathepsins for the liberation of thyroid hormones from the precursor thyroglobulin was previously shown by in vivo and in vitro studies. …”
Publicado 2020
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5178por Surani, Salim, Sharma, Munish, Middagh, Kevin, Bernal, Hector, Varon, Joseph, Ratnani, Iqbal, Anjum, Humayun, Khan, Alamgir“…CONCLUSION: Protocol-driven liberation from mechanical ventilation in LTAC by RT can significantly decrease the duration of a mechanical ventilator, leading to decreased mortality and cost savings.…”
Publicado 2020
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5179por Fite, Brett Z., Wang, James, Kare, Aris J., Ilovitsh, Asaf, Chavez, Michael, Ilovitsh, Tali, Zhang, Nisi, Chen, Weiyu, Robinson, Elise, Zhang, Hua, Kheirolomoom, Azadeh, Silvestrini, Matthew T., Ingham, Elizabeth S., Mahakian, Lisa M., Tam, Sarah M., Davis, Ryan R., Tepper, Clifford G., Borowsky, Alexander D., Ferrara, Katherine W.“…The tumor-specific antigen, cytokines and cell debris liberated by HIFU enhance response to innate immune agonists.…”
Publicado 2021
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5180“…We also review similar considerations for the lysosome where resident hydrolases liberate building blocks from luminal macromolecules and transporters flux these organic solutes to orchestrate trafficking events. …”
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