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  1. 5461
    “…Further studies are needed to detect the source of increased cf-mtDNA and the corresponding increase of suPAR liberation.…”
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    Increased level of circulating cell-free mitochondrial DNA due to a single bout of strenuous physical exercise
  2. 5462
    “…The structurally disordered N-terminal half of the prion protein (PrP(C)) is constitutively released into the extracellular space by an endogenous proteolytic cleavage event. Once liberated, this N1 fragment acts neuroprotective in ischemic conditions and interferes with toxic peptides associated with neurodegenerative diseases, such as amyloid-beta (Aβ) in Alzheimer’s disease. …”
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    Transgenic Overexpression of the Disordered Prion Protein N1 Fragment in Mice Does Not Protect Against Neurodegenerative Diseases Due to Impaired ER Translocation
  3. 5463
    “…The lysis of red blood cells was shown to occur in human ruptured atherosclerotic lesions and intraventricular hemorrhage (IVH) of the brain. Liberated cell-free hemoglobin was found to undergo oxidation in both pathologies. …”
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    Hemoglobin oxidation generates globin-derived peptides in atherosclerotic lesions and intraventricular hemorrhage of the brain, provoking endothelial dysfunction
  4. 5464
    “…Comparison of mean morphine dose utilized as liberation analgesic (in case of patients had VAS >3) between three groups was not significantly different (P = 0.17). …”
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    A Comparative Study of the Analgesic Effects of Intravenous Ketorolac, Paracetamol, and Morphine in Patients Undergoing Video-assisted Thoracoscopic Surgery: A Double-blind, Active-controlled, Randomized Clinical Trial
  5. 5465
    “…However, bearing in mind the rationales and their supporting arguments, economic interests and previous changes within the sector, it could be argued that an underlying rationale behind adopting the policy was to liberalize the Danish pharmacy sector even further.…”
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    Rationales and arguments behind the adoption of self-selection of nonprescription medicines in Denmark
  6. 5466
    “…IL6ri were initially reserved for critically ill patients, but after review, treatment was liberalized to patients with lower oxygen requirements. …”
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    Early administration of interleukin-6 inhibitors for patients with severe COVID-19 disease is associated with decreased intubation, reduced mortality, and increased discharge
  7. 5467
    “…RESULTS: Non-ventilated patients were liberated from supplemental oxygen after TPE. The response was rapid with an 87% average reduction in oxygenation requirements following and average time to return to room air of 5.25 days. …”
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    Efficacy of therapeutic plasma exchange in the treatment of penn class 3 and 4 cytokine release syndrome complicating COVID-19
  8. 5468
    “…Current ICU analgesia/sedation guidelines promote analgesia first and minimization of sedation, wakefulness, delirium prevention and early rehabilitation to facilitate ventilator and ICU liberation. However, these strategies cannot always be applied to patients with ARDS who sometimes require deep sedation and/or paralysis. …”
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    Analgesia and sedation in patients with ARDS
  9. 5469
    “…The consensus produced 36 statements (19 strong recommendations, 6 weak recommendations, 11 no recommendation) regarding airway management, non-invasive respiratory support, strategies for mechanical ventilation, rescue interventions for respiratory failure, ventilator liberation, and tracheostomy in brain-injured patients. …”
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    Mechanical ventilation in patients with acute brain injury: recommendations of the European Society of Intensive Care Medicine consensus
  10. 5470
    “…Chemistry looks back at many decades of publications on chemical compounds, their structures and properties, in scientific articles. Liberating this knowledge (semi-)automatically and making it available to the world in open-access databases is a current challenge. …”
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    DECIMER-Segmentation: Automated extraction of chemical structure depictions from scientific literature
  11. 5471
    “…Using a combination of SHAPE, DMS and enzymatic probing, we show that the disease-causing mutation disrupted a conserved AluJ stem that evolved from helix 3.3 (or 5b) of 7SL RNA, liberating a primordial GC 5ʹ splice site from the paired conformation for interactions with the spliceosome. …”
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    Transposon clusters as substrates for aberrant splice-site activation
  12. 5472
    “…The latter term covers hydrogen cyanide and cyanide compounds which easily liberate hydrogen cyanide under slightly acidic conditions. …”
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    Determination of low environmental free cyanide concentrations in freshwaters
  13. 5473
    “…Concurrently, red blood cell macrocytosis, low‐grade haemolysis and significant haemoglobin liberation from red blood cells were apparent in the peripheral blood of LEWzizi rats. …”
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    Iron accumulation in the choroid plexus, ependymal cells and CNS parenchyma in a rat strain with low‐grade haemolysis of fragile macrocytic red blood cells
  14. 5474
    por Savage, Nathan J, Albano, Joseph
    Publicado 2020
    “…INTRODUCTION: Hydrodissection has been used during injection procedures to liberate median nerve from surrounding adhesions. This investigation examined clinical and neurophysiologic impact of ultrasound-guided injections in patient with bilateral carpal tunnel syndrome (CTS) serving as own control. …”
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    Marrying Tendon and Nerve Gliding Exercises with Hydrodissection Following Injection for Carpal Tunnel Syndrome – A New Treatment Approach?
  15. 5475
    “…Dietary management was liberalized post LT for all patients. CONCLUSIONS: Referral for LT for IEMs has increased over the last 33 years, with the most referrals in the last 10 years. …”
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    Liver transplantation in children with inborn errors of metabolism: 30 years experience in NSW, Australia
  16. 5476
    “…MATERIAL/METHODS: Ninety-two patients who underwent percutaneous argon-helium cryoablation between February 2012 and December 2018 at the Fifth Medical Center of the Chinese People’s Liberation Army General Hospital were included. Treatment efficacy was evaluated by magnetic resonance imaging or triphasic computed tomography scan within 1 week after each cryoablation procedure. …”
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    Percutaneous Argon-Helium Cryoablation for Small Hepatocellular Carcinoma Located Adjacent to a Major Organ or Viscus: A Retrospective Study of 92 Patients at a Single Center
  17. 5477
    “…Some patients develop COVID-related acute respiratory distress syndrome (CARDS) and cannot be liberated from mechanical ventilation. Others may develop post-COVID fibrosis, resulting in substantial disability and need for long-term supplemental oxygen. …”
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    Lung Transplantation for Patients With COVID-19
  18. 5478
    “…BACKGROUND: β-amylase (EC 3.2.1.2) is an exo-enzyme that shows high specificity for cleaving the α-1,4-glucosidic linkage of starch from the non-reducing end, thereby liberating maltose. In this study, we heterologously expressed and characterized a novel β-amylase from Bacillus aryabhattai. …”
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    Expression, biochemical and structural characterization of high-specific-activity β-amylase from Bacillus aryabhattai GEL-09 for application in starch hydrolysis
  19. 5479
    “…HTx teams should consider liberalizing donor criteria and focusing only on evidence‐based selection to improve waitlist outcomes and reduce the recipient–donor disparity.…”
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    Donor Characteristics and Recipient Outcomes After Heart Transplantation in Adult Congenital Heart Disease
  20. 5480
    “…At high temperatures or upon chaperone overexpression, p53(V272M) is excluded from the nucleus and cannot function or perturb wild-type function. Hsp90 inhibition liberates mutant p53 to enter the nucleus. These findings provide new insights into the effects of missense mutations.…”
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    Selective functional inhibition of a tumor-derived p53 mutant by cytosolic chaperones identified using split-YFP in budding yeast
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