Mostrando 181 - 200 Resultados de 152,825 Para Buscar '"Lin An"', tiempo de consulta: 0.79s Limitar resultados
  1. 181
  2. 182
    “…Here we present a comparative analysis of LIN28-pre-let-7 UV-induced crosslinking using a tandem mass spectrometry (MS/MS) and deep sequencing interrogation of in vitro crosslinked complexes. …”
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  3. 183
    “…SpiLinC effectively recognizes a test pattern by combining the spiking activity of the constituent liquids, each of which identifies characteristic input features. …”
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  4. 184
    “…Our results show that a regulatory circuit formed by Wnt, Lin28a and let-7 miRNAs controls the deployment and the subsequent silencing of the multipotency program in a position-dependent manner. …”
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  5. 185
    “…OBJECTIVE: Recent studies have demonstrated that lin-28 homolog B (LIN28B)/miRNA let-7 (let-7) plays a role in the regulation of pubertal onset in mammals. …”
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  6. 186
    “…Here, we unravel a dual role of Mycb in lin28a expression, both as an activator through Ascl1a in MGPCs and a repressor in combination with Hdac1 in neighboring cells. …”
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  7. 187
    “…Our results highlight an important role for the LIN28B/LET-7 axis in human sarcoma pathogenesis and suggest that the therapeutic targeting of LIN28B may be relevant for patients with sarcoma.…”
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  8. 188
    “…Using proteomics and in situ analyses, we found that Lin28b (and its closely related paralog, Lin28a) directly interacted with Igf2bp3, another RBP, and their enforced co-expression in adult HSPCs reactivated fetal-like B-cell development in vivo more efficiently than either factor alone. …”
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  9. 189
  10. 190
    “…We identified a novel nonsense mutation (p.Gln368Ter) in the LINS1 gene which leads to loss of 389 amino acids in the C-terminus of the encoded protein. …”
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  11. 191
    “…Proliferating cells have high LIN28 and low let-7 miRNAs, whereas differentiating cells have low LIN28 and high let-7 miRNAs. …”
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  12. 192
    “…OBJECTIVE: Clinical, neuroimaging, and genetic characterization of 3 patients with LINS1-associated developmental regression, intellectual disability, dysmorphism, and further neurologic deficits. …”
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  13. 193
    “…ABSTRACT: Lin28A and Lin28B are two homologues of the same family of RNA binding proteins (RBPs). …”
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  14. 194
    “…During conservation of the painted ceiling decoration of Lin’xi Pavilion in the Forbidden City, two distinct paint campaigns were isolated as a unique case study into architectural paint materials during both the Ming and Qing dynasties. …”
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  15. 195
    por Lin, Chen, Gao, Shang, Yang, Ding
    Publicado 2021
    “…The dance fly Calohilara tibetensis Ding, He, Lin and Yang, 2020 belongs to the subfamily Empidinae of Empididae. …”
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  16. 196
    “…The occurrence and development of various malignant tumors is closely related with LIN28A gene, but its relationship with glioma susceptibility has not been widely discovered. …”
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  17. 197
    “…A loss-of-function variant in Lin-28 Homolog A gene (LIN28A p. R192G, rs558060339) has been identified in two East Asian ancestry patients with early-onset PD (EOPD). …”
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  18. 198
    “…BACKGROUND: LIN28B plays an important role in early embryonic development, but its role in villous trophoblast implantation and differentiation remains unknown. …”
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  19. 199
    “…Here we find that RNA binding proteins Lin28 and Imp mediate transcript stability of Bowl, a known hub specification factor; Bowl transcripts were reduced in the testis of Lin28 and Imp mutants, and also when RNA-mediated interference against Lin28 or Imp was expressed in hub cells. …”
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  20. 200
    “…Multimodal advances in single-cell sequencing have enabled the simultaneous quantification of cell surface protein expression alongside unbiased transcriptional profiling. Here, we present LinQ-View, a toolkit designed for multimodal single-cell data visualization and analysis. …”
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