Mostrando 141 - 160 Resultados de 152,825 Para Buscar '"Lin An"', tiempo de consulta: 0.73s Limitar resultados
  1. 141
    “…We demonstrate that LIN-12 modulates GABA signaling in this paradigm, as loss of GABA signaling suppresses LIN-12 gain-of-function defects. …”
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  2. 142
    “…Urban soils are strongly related to human health. In this study, Lin’an city was chosen as a typical small-scale city with which to study the spatial variation of potentially hazardous metals (PHMs) in urban soils and their potential ecological risks using multivariate analysis, geostatistics and GIS techniques. …”
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  3. 143
    “…The previous study showed that lin-28 homolog B (LIN28B) might play a role in the development of hepatoblastoma. …”
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  4. 144
    “…Using a murine xenograft model of neuroblastoma dissemination, we show that LIN28B promotes metastasis. We demonstrate that this is in part due to the effects of LIN28B on self-renewal and migration, providing an understanding of how LIN28B shapes the metastatic phenotype. …”
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  5. 145
    “…BACKGROUND: LIN28B is involved in multiple cellular developmental processes, tissue inflammatory response and tumourigenesis. …”
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  6. 146
    “…Embryonal tumor with multilayered rosettes (ETMR), is an aggressive brain tumor primarily occurring in young patients (<4 years of age) and characterized by C19MC amplification and Lin28 overexpression. These genetic hallmarks have been shown to participate in driving ETMR in a C19MC-Lin28-MYCN circuit. …”
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  7. 147
    “…Although it is known that both Lin28a and Lin28b regulate glucose metabolism, other molecular mechanisms that may protect against glucotoxicity are poorly understood. …”
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  8. 148
    “…Structural comparison of AncLinB-DmbA with their closely related descendants LinB and DmbA revealed some differences in overall structure and tunnel architecture. …”
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  9. 149
  10. 150
    “…An RNA-binding protein, LIN28A was initially discovered in nematodes Caenorhabditis elegans and regulated stem cell differentiation and proliferation. …”
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  11. 151
    “…We show that LinDA enjoys asymptotic FDR control and can be extended to mixed-effect models for correlated microbiome data. …”
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  12. 152
    “…METHODS: Using LIN28B knockdown and overexpression in G3 MB cells we test LIN28B’s effect on proliferation, self-renewal and metastasis. …”
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  13. 153
    “…Male reproductive development starts early in the embryogenesis with somatic and germ cell differentiation in the testis. The LIN28 family of RNA-binding proteins promoting pluripotency has two members—LIN28A and LIN28B. …”
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  14. 154
    “…Thus, Lin28 expresses only in the VMH neurons of the tuberal nuclei of the hypothalamus and the Lin 28 expression changes during the development together with the components of PI3K-Akt-mTOR signaling.…”
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  15. 155
  16. 156
    “…In this study, we compared the gene expression profiles of Lin-ckit+Sca-1+ (LKS) cells generated in vitro from mouse ESCs using either static or bioreactor-based cultures, with that of native LKS cells isolated from mouse fetal liver (FL) or bone marrow (BM). …”
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  17. 157
    por Lin, Yuh-Lang
    Publicado 2007
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  18. 158
    “…To better understand lin-39 regulation and function, we aimed to identify transcription factors necessary for lin-39 expression in the VPCs, and in particular sought factors that initiate lin-39 expression in the embryo. …”
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  19. 159
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